Design and development of a quantitative real time PCR assay for monitoring of HTLV-1 provirus in whole blood

Journal of Clinical Virology

Volumn 53, Issue 4, 2012, Pages 302-307

  Naderi, Mahmood ^a,b,e   Paryan, Mahdi ^b,c,e   Azadmanesh, Kayhan ^c   Rafatpanah, Houshang ^d   Rezvan, Houri ^e   Mirab Samiee, Siamak ^e,f  

^a TARBIAT MODARES UNIVERSITY   (Iran)

^b STEM CELL TECHNOLOGY RESEARCH CENTER   (Iran)

^c PASTEUR INSTITUTE OF IRAN   (Iran)

^d MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^e Day General Hospital Laboratory   (Iran)

^f MINISTRY OF HEALTH AND MEDICAL EDUCATION   (Iran)

Author keywords

HTLV 1; Proviral load; Quantitative real time PCR; Tax

Indexed keywords

TAX PROTEIN;

ARTICLE; GENE SEQUENCE; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HUMAN T CELL LEUKEMIA VIRUS 1; LIMIT OF DETECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; VIRUS LOAD;

CELL LINE; DNA PRIMERS; DNA, VIRAL; GENE PRODUCTS, TAX; HTLV-I INFECTIONS; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMANS; PROVIRUSES; REAL-TIME POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; VIRAL LOAD;

EID: 84858161421     PISSN: 13866532     EISSN: 18735967     Source Type: Journal    
DOI: 10.1016/j.jcv.2011.12.033     Document Type: Article

References (39)

1. Blattner W.A., Takatsuki K., Gallo R.C. Human T-cell leukemia-lymphoma virus and adult T-cell leukemia. JAMA 1983, 250:1074-1080.
2. Furnia A., Lal R., Maloney E., Wiktor S., Pate E., Rudolph D., et al. Estimating the time of HTLV-I infection following mother-to-child transmission in a breast-feeding population in Jamaica. J Med Virol 1999, 59:541-546.
3. Uchiyama T., Yodoi J., Sagawa K., Takatsuki K., Uchino H. Adult T-cell leukemia: clinical and hematologic features of 16 cases. Blood 1977, 50:481-492.
4. Gessain A., Barin F., Vernant J.C., Gout O., Maurs L., Calender A., et al. Antibodies to human T-lymphotropic virus type-I in patients with tropical spastic paraparesis. Lancet 1985, 2:407-410.
5. Gessain A., Mahieux R. Epidemiology, origin and genetic diversity of HTLV-1 retrovirus and STLV-1 simian affiliated retrovirus. Bull Soc Pathol Exot 2000, 93:163-171.
6. Abbaszadegan M.R., Gholamin M., Tabatabaee A., Farid R., Houshmand M., Abbaszadegan M. Prevalence of human T-lymphotropic virus type 1 among blood donors from Mashhad, Iran. J Clin Microbiol 2003, 41:2593-2595.
7. Rezvan H., Ahmadi J., Farhadi M. A cluster of HTLV-I, II infection in north-eastern Iran. Transfusion Today 1996, 27:8-9.
8. Safai B., Huang J.L., Boeri E., Farid R., Raafat J., Schutzer P., et al. Prevalence of HTLV type I infection in Iran: a serological and genetic study. AIDS Res Hum Retroviruses 1996, 12:1185-1190.
9. Take H., Umemoto M., Kusuhara K., Kuraya K. Transmission routes of HTLV-I: an analysis of 66 families. Jpn J Cancer Res 1993, 84:1265-1267.
10. Yao F., Seed C., Farrugia A., Morgan D., Cordner S., Wood D., et al. The risk of HIV, HBV, HCV and HTLV infection among musculoskeletal tissue donors in Australia. Am J Transplant 2007, 7:2723-2726.
11. Zou S., Dodd R.Y., Stramer S.L., Strong D.M. Probability of viremia with HBV, HCV, HIV, and HTLV among tissue donors in the United States. N Engl J Med 2004, 351:751-759.
12. Berini C.A., Eirin M.E., Pando M.A., Biglione M.M. Human T-cell lymphotropic virus types I and II (HTLV-I and -II) infection among seroindeterminate cases in Argentina. J Med Virol 2007, 79:69-73.
13. Yao K., Hisada M., Maloney E., Yamano Y., Hanchard B., Wilks R., et al. Human T lymphotropic virus types I and II western blot seroindeterminate status and its association with exposure to prototype HTLV-I. J Infect Dis 2006, 193:427-437.
14. Cooke F.J., Geretti A.M., Zuckerman M. Human T-cell lymphotropic virus antibody prevalence in HIV-1-infected individuals attending a sexual health clinic in South-East London. J Med Virol 2005, 76:143-145.
15. Thorstensson R., Albert J., Andersson S. Strategies for diagnosis of HTLV-I and -II. Transfusion 2002, 42:780-791.
16. Abbaszadegan M.R., Jafarzadeh N., Sankian M., Varasteh A., Mahmoudi M., Sadeghizadeh M., et al. Truncated MTA-1: a pitfall in ELISA-based immunoassay of HTLV-1 infection. J Biomed Biotechnol 2008, 2008:846371.
17. Yakova M., Lezin A., Dantin F., Lagathu G., Olindo S., Jean-Baptiste G., et al. Increased proviral load in HTLV-1-infected patients with rheumatoid arthritis or connective tissue disease. Retrovirology 2005, 2:4.
18. Kubota R., Nagai M., Kawanishi T., Osame M., Jacobson S. Increased HTLV type 1 tax specific CD8+ cells in HTLV type 1-asociated myelopathy/tropical spastic paraparesis: correlation with HTLV type 1 proviral load. AIDS Res Hum Retroviruses 2000, 16:1705-1709.
19. Kchour G., Makhoul N.J., Mahmoudi M., Kooshyar M.M., Shirdel A., Rastin M., et al. Zidovudine and interferon-alpha treatment induces a high response rate and reduces HTLV-1 proviral load and VEGF plasma levels in patients with adult T-cell leukemia from North East Iran. Leuk Lymphoma 2007, 48:330-336.
20. Vitone F., Gibellini D., Schiavone P., D'Antuono A., Gianni L., Bon I., et al. Human T-lymphotropic virus type 1 (HTLV-1) prevalence and quantitative detection of DNA proviral load in individuals with indeterminate/positive serological results. BMC Infect Dis 2006, 6:41.
21. Iwanaga M., Watanabe T., Utsunomiya A., Okayama A., Uchimaru K., Koh K.R., et al. Human T-cell leukemia virus type I (HTLV-1) proviral load and disease progression in asymptomatic HTLV-1 carriers: a nationwide prospective study in Japan. Blood 2010, 116:1211-1219.
22. Primo J., Siqueira I., Nascimento M.C., Oliveira M.F., Farre L., Carvalho E.M., et al. High HTLV-1 proviral load, a marker for HTLV-1 associated myelopathy/tropical spastic paraparesis, is also detected in patients with infective dermatitis associated with HTLV-1. Braz J Med Biol Res 2009, 42:761-764.
23. Miyoshi I., Kubonishi I., Yoshimoto S., Shiraishi Y.A. T-cell line derived from normal human cord leukocytes by co-culturing with human leukemic T-cells. Gann 1981, 72:978-981.
24. Dehee A., Cesaire R., Desire N., Lezin A., Bourdonne O., Bera O., et al. Quantitation of HTLV-I proviral load by a TaqMan real-time PCR assay. J Virol Methods 2002, 102:37-51.
25. Lee T.H., Chafets D.M., Busch M.P., Murphy E.L. Quantitation of HTLV-I and II proviral load using real-time quantitative PCR with SYBR Green chemistry. J Clin Virol 2004, 31:275-282.
26. Yamano Y., Nagai M., Brennan M., Mora C.A., Soldan S.S., Tomaru U., et al. Correlation of human T-cell lymphotropic virus type 1 (HTLV-1) mRNA with proviral DNA load, virus-specific CD8(+) T cells, and disease severity in HTLV-1-associated myelopathy (HAM/TSP). Blood 2002, 99:88-94.
27. Zhou J., Hu J., Guan H. The association between copy number variations in glutathione S-transferase M1 and T1 and age-related cataract in a Han Chinese population. Invest Ophthalmol Vis Sci 2010, 51:3924-3928.
28. Tamura K., Dudley J., Nei M., Kumar S. MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol Biol Evol 2007, 24:1596-1599.
29. Dimech W., Bowden D.S., Brestovac B., Byron K., James G., Jardine D., et al. Validation of assembled nucleic acid-based tests in diagnostic microbiology laboratories. Pathology 2004, 36:45-50.
30. Rabenau H.F., Kessler H.H., Kortenbusch M., Steinhorst A., Raggam R.B., Berger A. Verification and validation of diagnostic laboratory tests in clinical virology. J Clin Virol 2007, 40:93-98.
31. Van Dooren S., Pybus O.G., Salemi M., Liu H.F., Goubau P., Remondegui C., et al. The low evolutionary rate of human T-cell lymphotropic virus type-1 confirmed by analysis of vertical transmission chains. Mol Biol Evol 2004, 21:603-611.
32. Korn K., Weissbrich B., Henke-Gendo C., Heim A., Jauer C.M., Taylor N., et al. Single-point mutations causing more than 100-fold underestimation of human immunodeficiency virus type 1 (HIV-1) load with the Cobas TaqMan HIV-1 real-time PCR assay. J Clin Microbiol 2009, 47:1238-1240.
33. Brambilla D., Reichelderfer P.S., Bremer J.W., Shapiro D.E., Hershow R.C., Katzenstein D.A., et al. The contribution of assay variation and biological variation to the total variability of plasma HIV-1 RNA measurements. The Women Infant Transmission Study Clinics. Virology Quality Assurance Program. Aids 1999, 13:2269-2279.
34. Madej R. Using standards and controls in molecular assays for infectious diseases. Mol Diagn 2001, 6:335-345.
35. Kira J., Koyanagi Y., Yamada T., Itoyama Y., Goto I., Yamamoto N., et al. Increased HTLV-I proviral DNA in HTLV-I-associated myelopathy: a quantitative polymerase chain reaction study. Ann Neurol 1991, 29:194-201.
36. Nagai M., Usuku K., Matsumoto W., Kodama D., Takenouchi N., Moritoyo T., et al. Analysis of HTLV-I proviral load in 202 HAM/TSP patients and 243 asymptomatic HTLV-I carriers: high proviral load strongly predisposes to HAM/TSP. J Neurovirol 1998, 4:586-593.
37. Goncalves D.U., Proietti F.A., Barbosa-Stancioli E.F., Martins M.L., Ribas J.G., Martins-Filho O.A., et al. HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) inflammatory network. Inflamm Allergy Drug Targets 2008, 7:98-107.
38. Amano M., Kurokawa M., Ogata K., Itoh H., Kataoka H., Setoyama M. New entity, definition and diagnostic criteria of cutaneous adult T-cell leukemia/lymphoma: human T-lymphotropic virus type 1 proviral DNA load can distinguish between cutaneous and smoldering types. J Dermatol 2008, 35:270-275.
39. Besson G., Kazanji M. One-step, multiplex, real-time PCR assay with molecular beacon probes for simultaneous detection, differentiation, and quantification of human T-cell leukemia virus types 1, 2, and 3. J Clin Microbiol 2009, 47:1129-1135.