Drug recrystallization using supercritical anti-solvent (SAS) process with impinging jets: Effect of process parameters

Journal of Crystal Growth

Volumn 342, Issue 1, 2012, Pages 34-41

  Careno, Stéphanie ^a   Boutin, Olivier ^a   Badens, Elisabeth ^a  

^a CNRS   (France)

Author keywords

A2. Recrystallization; B1. Organic compounds

Indexed keywords

ACETONE SOLUTION; FINER PARTICLES; HOMOGENEOUS MORPHOLOGY; IMPINGING JET; MEAN PARTICLE SIZE; MOLAR RATIO; OPERATING CONDITION; ORGANIC SOLUTIONS; POLYMORPHIC FORMS; POORLY WATER-SOLUBLE DRUGS; POWDER CHARACTERISTICS; PROCESS PARAMETERS; SIZE CONTROL; SULFATHIAZOLE; SUPERCRITICAL ANTISOLVENTS;

ACETONE; METHANOL; PARTICLE SIZE; RECRYSTALLIZATION (METALLURGY); SIZE DISTRIBUTION; SOLVENTS;

ORGANIC SOLVENTS;

EID: 84858154825     PISSN: 00220248     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcrysgro.2011.06.059     Document Type: Conference Paper

References (31)

1. S.-D. Yeo, M.-S. Kim, and J.-C. Lee Recrystallization of sulfathiazole and chlorpropamide using the supercritical fluid anti-solvent process Journal of Supercritical Fluids 25 2003 143 154
2. Y. Wang, Y. Wang, J. Yang, R. Pfeffer, R. Dave, and B. Michniak The application of a supercritical anti-solvent process for sustained drug delivery Powder Technology 164 2006 94 102
3. M.-S. Kim, S. Lee, J.-S. Park, J.-S. Woo, and S.-J. Hwang Micronization of cilostazol using supercritical anti-solvent (SAS) process: effect of process parameters Powder Technology 177 2007 64 70 (Pubitemid 47224964)
4. M. Bahrami, and S. Ranjbarian Production of micro- and nano-composite particles by supercritical carbon dioxide Journal of Supercritical Fluids 40 2007 263 283 (Pubitemid 46172528)
5. G. Caputo, and E. Reverchon Use of Urea as Habit Modifier in the Supercritical Anti-solvent Micronization of Sulfathiazole Industrial and Engineering Chemistry Research 46 12 2007 4265 4272 (Pubitemid 46982437)
6. E. Reverchon, R. Adami, G. Caputo, and I. De Marco Spherical microparticles production by supercritical anti-solvent precipitation: Interpretation of results Journal of Supercritical Fluids 47 2008 70 84
7. K. Byrappa, S. Ohara, and T. Adschiri Nanoparticles synthesis using supercritical fluid technology - towards biomedical applications Advanced Drug Delivery Reviews 60 2008 299 327
8. O. Boutin, C. Maruejouls, and G. Charbit A new system for particle formation using the principle of the SAS process: the concentric tube anti-solvent reactor (CTAR) Journal of Supercritical Fluids 40 2007 443 451 (Pubitemid 46330685)
9. H. Steckel, J. Thies, and B.W. Müller Micronizing of steroids for pulmonary delivery by supercritical carbon dioxide International Journal of Pharmaceutics 152 1997 99 110 (Pubitemid 27254966)
10. J. Chua, G. Li, K. Ho Row, H. Kim, and Y.-W. Lee Preparation of cefpodoxime proxetil fine particles using supercritical fluids International Journal of Pharmaceutics 369 2009 85 91
11. A.J. Thote, and R.B. Gupta Formation of nanoparticles of a hydrophilic drug using supercritical carbon dioxide and microencapsulation for sustained release Nanomedicine: Nanotechnology, Biology and Medicine 1 2005 85 90 (Pubitemid 43963611)
12. L.Y. Lee, C.H. Wang, and K.A. Smith Supercritical anti-solvent production of biodegradable micro- and nanoparticles for controlled delivery of paclitaxel Journal of Controlled Release 125 2008 96 106 (Pubitemid 350299604)
13. M. Rehman, B.Y. Shekunov, P. York, D. Lechuga-Ballesteros, D.P. Miller, T. Tan, and P. Colthorpe Optimisation of powders for pulmonary delivery using supercritical fluid technology European Journal of Pharmaceutical Sciences 22 2004 1 17 (Pubitemid 38543009)
14. Q.L. Suo, W.Z. He, Y.C. Huang, C.P. Li, H.L. Hong, Y.X. Li, and M.D. Zhu Micronization of the natural pigment-bixin by the SEDS process through prefilming atomization Powder Technology 154 2005 110 115
15. B.K. Johnson, and R.K. Prudhomme Chemical processing and micro-mixing in confined impinging jets AIChE Journal 49 2003 2264 2282 (Pubitemid 37163187)
16. E. Gavi, L. Rivautella, D.L. Marchisio, M. Vanni, A.A. Barresi, and G. Baldi CFD Modelling of Nano-Particle Precipitation in Confined Impinging Jet Reactors Chemical Engineering Research and Design 85 2007 735 744 (Pubitemid 46979082)
17. E. Gavi, D.L. Marchisio, and A.A. Barresi CFD Modelling and scale-up of Confined Impinging Jet Reactors Chemical Engineering Science 62 2007 2228 2241 (Pubitemid 46399653)
18. F. Lince, D.L. Marchisio, and A.A. Barresi Strategies to control the particle size distribution of poly-ε-caprolactone nanoparticles for pharmaceutical applications Journal of Colloid and Interface Science 322 2008 505 515
19. F. Lince, D.L. Marchisio, and A.A. Barresi Smart mixers and reactors for the production of pharmaceutical nanoparticles: proof of concept Chemical Engineering Research and Design 87 2009 543 549
20. H. Chiou, H.-K. Chan, D. Heng, R.K. Prudhomme, and J.A. Raper A novel production method for inhalable cyclosporine A powders by confined liquid impinging jet precipitation Journal of Aerosol Science 39 2008 500 509
21. N. Bénet, H. Muhr, E. Plasari, and J.M. Rousseaux New technologies for the precipitation of solid particles with controlled properties Powder Technology 128 2002 93 98 (Pubitemid 35365744)
22. M. Midler, E.L. Paul, E.F. Whittington, M. Futran, P.D. Liu, J. Hsu, S.H. Pan, Crystallization method to improve crystal structure and size, US Patent Application No. 5314506, 24 May 1994.
23. A. Tsutsumi, M. Ikeda, W. Chen, and J. Iwatsuki A nano-coating process by the rapid expansion of supercritical suspensions in impinging-stream reactors Powder Technology 138 2003 211 215 (Pubitemid 37491297)
24. B. Calvignac, and O. Boutin The impinging jets technology: A contacting device using a SAS process type Powder Technology 191 2009 200 205
25. D.C. Apperley, R.A. Fletton, R.K. Harris, R.W. Lancaster, S. Tavener, and T.L. Threlfall Sulfathiazole polymorphism studied by magic-angle spinning NMR Journal of Pharmaceutical Sciences 88 1999 1275 1280
26. N. Blagden, R.J. Davey, H.F. Lieberman, L. Williams, R. Payne, R. Roberts, R. Rowe, and R. Docherty Crystal chemistry and solvent effects in polymorphic systems sulfathiazole Journal of the Chemical Society, Faraday Transactions 94 1998 1035 1044 (Pubitemid 128774389)
27. M. Kitamura, M. Yamamoto, Y. Yoshinaga, and H. Masuoka Crystal size control of sulfathiazole using high pressure carbon dioxide Journal of Crystal Growth 178 1997 378 386 (Pubitemid 127392707)
28. T. Petit-Gas, O. Boutin, I. Raspo, and E. Badens Role of hydrodynamics in supercritical anti-solvent processes Journal of Supercritical Fluids 51 2009 248 255
29. 2 Pharmaceutical Research 18 5 2001 682 688 (Pubitemid 32595799)
30. J.C. Hooton, C.S. German, M.C. Davies, and C.J. Roberts A comparison of morphology and surface energy characteristics of sulfathiazole polymorphs based upon single particle studies European Journal of Pharmaceutical Sciences 28 2006 315 324 (Pubitemid 44218738)
31. 2 at elevated pressures Journal of Chemical Engineering Data 41 1996 839 843 (Pubitemid 126544285)