Mouse model of oropharyngeal candidiasis

Nature Protocols

Volumn 7, Issue 4, 2012, Pages 637-642

  Solis, Norma V ^a   Filler, Scott G ^a,b  

^a HARBOR UCLA MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANDIDA ALBICANS; DISEASE MODEL; DISEASE SEVERITY; HISTOPATHOLOGY; INFECTION SENSITIVITY; NONHUMAN; OROPHARYNX CANDIDIASIS; PRIORITY JOURNAL;

ANIMALS; CANDIDA ALBICANS; CANDIDIASIS, ORAL; CORTISONE; DISEASE MODELS, ANIMAL; IMMUNOSUPPRESSIVE AGENTS; MICE; MICE, INBRED BALB C; PHARYNGEAL DISEASES;

ANIMALIA; CANDIDA ALBICANS; MUS;

EID: 84858129679     PISSN: 17542189     EISSN: 17502799     Source Type: Journal    
DOI: 10.1038/nprot.2012.011     Document Type: Article

References (32)

1. Sangeorzan, J.A. et al. Epidemiology of oral candidiasis in HIV-infected patients: colonization, infection, treatment, and emergence of fluconazole resistance. Am. J. Med. 97, 339-346 (1994).
2. Rhodus, N.L., Bloomquist, C., Liljemark, W. & Bereuter, J. Prevalence, density, and manifestations of oral Candida albicans in patients with Sjogren's syndrome. J. Otolaryngol. 26, 300-305 (1997).
3. Willis, A.M. et al. Oral candidal carriage and infection in insulin-treated diabetic patients. Diabet. Med. 16, 675-679 (1999).
4. Redding, S.W. et al. Epidemiology of oropharyngeal Candida colonization and infection in patients receiving radiation for head and neck cancer.J. Clin. Microbiol. 37, 3896-3900 (1999).
5. Arribas, J.R. et al. Impact of protease inhibitor therapy on HIV-related oropharyngeal candidiasis. AIDS 14, 979-985 (2000).
6. Martins, M.D., Lozano-Chiu, M. & Rex, J.H. Declining rates of oropharyngeal candidiasis and carriage of Candida albicans associated with trends toward reduced rates of carriage of fluconazole-resistant C. albicans in human immunodeficiency virus-infected patients. Clin. Infect. Dis. 27, 1291-1294 (1998).
7. Kerdpon, D. et al. Oral manifestations of HIV infection in relation to clinical and CD4 immunological status in northern and southern Thai patients. Oral Dis. 10, 138-144 (2004).
8. Chidzonga, M.M. HIV/AIDS orofacial lesions in 156 Zimbabwean patients at referral oral and maxillofacial surgical clinics. Oral Dis. 9, 317-322 (2003).
9. Revankar, S.G. et al. Clinical evaluation and microbiology of oropharyngeal infection due to fluconazole-resistant Candida in human immunodeficiency virus-infected patients. Clin. Infect. Dis. 26, 960-963 (1998).
10. Pappas, P.G. et al. Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America. Clin. Infect. Dis. 48, 503-535 (2009).
11. Conti, H.R. et al. Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis. J. Exp. Med. 206, 299-311 (2009).
12. Saunus, J.M. et al. Early activation of the interleukin-23-17 axis in a murine model of oropharyngeal candidiasis. Mol. Oral Microbiol. 25, 343-356 (2010).
13. Ho, A.W. et al. IL-17RC is required for immune signaling via an extended SEF/IL-17R signaling domain in the cytoplasmic tail. J. Immunol. 185, 1063-1070 (2010).
14. Nett, J.E., Marchillo, K., Spiegel, C.A. & Andes, D.R. Development and validation of an in vivo Candida albicans biofilm denture model. Infect. Immun. 78, 3650-3659 (2010).
15. Sun, J.N. et al. Host cell invasion and virulence mediated by Candida albicans Ssa1. PLoS Pathog. 6, e1001181 (2010).
16. Chiang, L.Y. et al. Candida albicans protein kinase CK2 governs virulence during oropharyngeal candidiasis. Cell Microbiol. 9, 233-245 (2007).
17. Park, H. et al. Role of the fungal Ras-protein kinase A pathway in governing epithelial cell interactions during oropharyngeal candidiasis. Cell Microbiol. 7, 499-510 (2005).
18. Kamai, Y., Kubota, M., Hosokawa, T., Fukuoka, T. & Filler, S.G. Contribution of Candida albicans ALS1 to the pathogenesis of experimental oropharyngeal candidiasis. Infect. Immun. 70, 5256-5258 (2002).
19. Dwivedi, P. et al. Role of Bcr1-activated genes Hwp1 and Hyr1 in Candida albicans oral mucosal biofilms and neutrophil evasion. PLoS ONE 6, e16218 (2011).
20. Hao, B. et al. Candida albicans RFX2 encodes a DNA binding protein involved in DNA damage responses, morphogenesis, and virulence. Eukaryot. Cell 8, 627-639 (2009).
21. Marquis, M. et al. CD8+ T cells but not polymorphonuclear leukocytes are required to limit chronic oral carriage of Candida albicans in transgenic mice expressing human immunodeficiency virus type 1. Infect. Immun. 74, 2382-2391 (2006).
22. Sundstrom, P., Balish, E. & Allen, C.M. Essential role of the Candida albicans transglutaminase substrate, hyphal wall protein 1, in lethal oroesophageal candidiasis in immunodeficient mice. J. Infect. Dis. 185, 521-530 (2002).
23. Wolf, J.M., Johnson, D.J., Chmielewski, D. & Davis, D.A. The Candida albicans ESCRT pathway makes Rim101-dependent and -independent contributions to pathogenesis. Eukaryot. Cell 9, 1203-1215 (2010).
24. Spellberg, B.J. et al. Efficacy of the anti-Candida rAls3p-N or rAls1p-N vaccines against disseminated and mucosal candidiasis. J. Infect. Dis. 194, 256-260 (2006).
25. Kamai, Y., Kubota, M., Hosokawa, T., Fukuoka, T. & Filler, S.G. New model of oropharyngeal candidiasis in mice. Antimicrob. Agents Chemother. 45, 3195-3197 (2001).
26. Rahman, D., Mistry, M., Thavaraj, S., Challacombe, S.J. & Naglik, J.R. Murine model of concurrent oral and vaginal Candida albicans colonization to study epithelial host-pathogen interactions. Microbes. Infect. 9, 615-622 (2007).
27. Naglik, J.R., Fidel, P.L. Jr. & Odds, F.C. Animal models of mucosal Candida infection. FEMS Microbiol. Lett. 283, 129-139 (2008).
28. Rachelefsky, G.S., Liao, Y. & Faruqi, R. Impact of inhaled corticosteroid-induced oropharyngeal adverse events: results from a meta-analysis. Ann. Allergy Asthma Immunol. 98, 225-238 (2007).
29. Farah, C.S. et al. Primary role for CD4+ T lymphocytes in recovery from oropharyngeal candidiasis. Infect. Immun. 70, 724-731 (2002).
30. Cantorna, M.T. & Balish, E. Mucosal and systemic candidiasis in congenitally immunodeficient mice. Infect. Immun. 58, 1093-1100 (1990).
31. de Repentigny, L. et al. Mucosal candidiasis in transgenic mice expressing human immunodeficiency virus type 1. J. Infect. Dis. 185, 1103-1114 (2002).
32. Cheng, S. et al. The role of Candida albicans NOT5 in virulence depends upon diverse host factors in vivo. Infect. Immun. 73, 7190-7197 (2005).