Essential role of the Candida albicans transglutaminase substrate, hyphal wall protein 1, in lethal oroesophageal candidiasis in immunodeficient mice

Journal of Infectious Diseases

Volumn 185, Issue 4, 2002, Pages 521-530

  Sundstrom, Paula ^a,b   Balish, Edward ^d,e   Allen, Carl M ^c  

^a 2078 Graves Hall   (United States)

^b Department of Entomology   (United States)

^c OHIO STATE UNIVERSITY   (United States)

^d UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^e MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; GENE PRODUCT; HYPHAL WALL PROTEIN 1; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CANDIDIASIS; ENZYME SUBSTRATE; FEMALE; HYPHEN WALL; IMMUNE DEFICIENCY; INFECTION RISK; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; THRUSH;

ANIMALS; CANDIDA ALBICANS; CANDIDIASIS; CANDIDIASIS, ORAL; DIGESTIVE SYSTEM; ESOPHAGEAL DISEASES; ESOPHAGUS; FEMALE; FUNGAL PROTEINS; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; MICE; SURVIVAL RATE; TONGUE; VIRULENCE;

EID: 0037083242     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/338836     Document Type: Article

References (27)

1. Assessment of therapeutic response of oropharyngeal and esophageal candidiasis in AIDS with use of a new clinical scoring system: Studies with D0870
2. Oral mucositis in myelosuppressive cancer therapy
3. Diseases of the esophagus
4. Esophageal candidiasis in pediatric acquired immunodeficiency syndrome: Clinical manifestations and risk factors
5. The role of gastrointestinal tract in hematogenous candidiasis: From the laboratory to the bedside
6. Relationship between germination of Candida albicans and increased adherence to human buccal epithelial cells
7. Adhesive and mammalian transglutaminase substrate properties of Candida albicans Hwp1
8. Developmental expression of a tandemly repeated, proline- and glutamine-rich amino acid motif on hyphal surfaces on Candida albicans
9. Elevated expression of transglutaminase 1 and keratinization-related proteins in conjunctiva in severe ocular surface disease
10. Facilitated wound healing by activation of the transglutaminase 1 gene
11. Transglutaminase type 1 and its cross-linking activity are concentrated at adherens junctions in simple epithelial cells
12. Initiation of assembly of the cell envelope barrier structure of stratified squamous epithelia
13. Mucosal and systemic candidiasis in congenitally immunodeficient mice
14. A block in both early T lymphocyte and natural killer cell development in transgenic mice with high-copy numbers of the human CD3 ε gene
15. Oroesophageal candidiasis is lethal for transgenic mice with combined natural killer and T-cell defects
16. Isolation of the Candida albicans gene for orotidine-5′-phosphate decarboxylase by complementation of Saccharomyces cerevisiae ura3 and Escherichia coli pyrF mutations
17. Isogenic strain construction and gene mapping in Candida albicans
18. Evidence that two independent host genes influence the severity of tissue damage and susceptibility to acute pyelonephritis in murine systemic candidiasis
19. Host-pathogen interactions: Redefining the basic concepts of virulence and pathogenicity
20. Esophageal candidosis in progressive systemic sclerosis: Occurrence, significance, and treatment with fluconazole
21. Neurobeachin: A protein kinase A-anchoring, beige/Chediak-Higashi protein homolog implicated in neuronal membrane traffic
22. Identification of the homologous beige and Chediak-Higashi syndrome genes
23. Defective killing of Candida albicans hyphae by neutrophils from beige mice
24. Fungal infections in patients with neutropenia: Challenges in prophylaxis and treatment
25. Cellular and cytokine correlates of mucosal protection in murine model of oral candidiasis
26. Requirement for the Candida albicans FAS2 gene for infection in a rat model of oropharyngeal candidiasis