CD8+ T cells but not polymorphonuclear leukocytes are required to limit chronic oral carriage of Candida albicans in transgenic mice expressing human immunodeficiency virus type 1

Infection and Immunity

Volumn 74, Issue 4, 2006, Pages 2382-2391

  Marquis, Miriam ^a   Lewandowski, Daniel ^a   Dugas, Véronique ^a   Aumont, Francine ^a   Sénéchal, Serge ^a   Jolicoeur, Paul ^a,c,d   Hanna, Zaher ^a,c,d   De Repentigny, Louis ^a,b,e  

^a Department of Microbiology and Immunology ^*  (Canada)

^b UNIVERSITY OF MONTREAL   (Canada)

^c CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^d MCGILL UNIVERSITY   (Canada)

^e UNIVERSITY OF MONTREAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

NEF PROTEIN; REV PROTEIN; VIRUS ENVELOPE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANDIDA ALBICANS; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; HETEROZYGOSITY; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOCOMPETENT CELL; LEUKOCYTE COUNT; MOUSE; NEUTROPHIL; NONHUMAN; OROPHARYNX CANDIDIASIS; PHAGOCYTOSIS; PRIORITY JOURNAL; RESPIRATORY BURST; TRANSGENIC MOUSE;

ANIMALS; ANTIGENS, CD4; ANTIGENS, CD8; CANDIDA ALBICANS; CANDIDIASIS, ORAL; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; FEMALE; HIV INFECTIONS; HIV-1; HUMANS; LEUKOPENIA; MALE; MICE; MICE, INBRED C3H; MICE, KNOCKOUT; MICE, TRANSGENIC; NEUTROPHILS; PHAGOCYTOSIS; RESPIRATORY BURST; TIME FACTORS;

EID: 33645505369     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.74.4.2382-2391.2006     Document Type: Article

References (49)

1. Balish, E., H. Filutowicz, and T. D. Oberley. 1990. Correlates of cell-mediated immunity in Candida albicans-colonized gnotobiotic mice. Infect. Immun. 58:107-113.
2. Balish, E., J. Jensen, T. Warner, J. Brekke, and B. Leonard. 1993. Mucosal and disseminated candidiasis in gnotobiotic SCID mice. J. Med. Vet. Mycol. 31:143-154.
3. Balish, E., F. A. Vazquez-Torres, J. Jones-Carson, R. D. Wagner, and T. Warner. 1996. Importance of β2-microglobulin in murine resistance to mucosal and systemic candidiasis. Infect. Immun. 64:5092-5097.
4. Bandres, J. C., J. Trial, D. M. Musher, and R. D. Rossen. 1993. Increased phagocytosis and generation of reactive oxygen products by neutrophils and monocytes of men with stage 1 human immunodeficiency virus infection. J. Infect. Dis. 168:75-83.
5. Beno, D. W., A. G. Stover, and H. L. Mathews. 1995. Growth inhibition of Candida albicans hyphae by CD8+ lymphocytes. J. Immunol. 154:5273-5281.
6. + lymphocytes in resistance to mucosal candidiasis. Infect. Immun. 59:2447-2455.
7. Cantorna, M. T., and E. Balish. 1990. Mucosal and systemic candidiasis in congenitally immunodeficient mice. Infect. Immun. 58:1093-1100.
8. Cassone, A., C. Palma, J. Y. Djeu, F. Aiuti, and I. Quinti. 1993. Anticandidal activity and interleukin-1β and interleukin-6 production by polymorphonuclear leukocytes are preserved in subjects with AIDS. J. Clin. Microbiol. 31:1354-1357.
9. Cenci, E., A. Mencacci, R. Spaccapelo, L. Tonnetti, P. Mosci, K. H. Enssle, P. Puccetti, L. Romani, and F. Bistoni. 1995. T helper cell type 1 (Th1)- and Th2-like responses are present in mice with gastric candidiasis but protective immunity is associated with Th1 development. J. Infect. Dis. 171:1279-1288.
10. Chakir, J., L. Cote, C. Coulomhe, and N. Deslauriers. 1994. Differential pattern of infection and immune response during experimental oral candidiasis in BALB/c and DBA/2 (H-2d) mice. Oral Microbiol. Immunol. 9:88-94.
11. Chen, T. P., R. L. Roberts, K. G. Wu, B. J. Ank, and E. R. Stiehm. 1993. Decreased superoxide anion and hydrogen peroxide production by neutrophils and monocytes in human immunodeficiency virus-infected children and adults. Pediatr. Res. 34:544-550.
12. Christin, L., D. R. Wysong, T. Meshulam, S. Wang, and R. D. Diamond. 1997. Mechanisms and target sites of damage in killing of Candida albicans hyphae by human polymorphonuclear neutrophils. J. Infect. Dis. 176:1567-1578.
13. de Repentigny, L., F. Aumont, J. S. Ripeau, M. Fiorillo, D. G. Kay, Z. Hanna, and P. Jolicoeur. 2002. Mucosal candidiasis in transgenic mice expressing human immunodeficiency virus type 1. J. Infect. Dis. 185:1103-1114.
14. de Repentigny, L., D. Lewandowski, and P. Jolicoeur. 2004. Immunopathogenesis of oropharyngeal candidiasis in human immunodeficiency virus infection. Clin. Microbiol. Rev. 17:729-759.
15. Deslauriers, N., L. Cote, S. Montplaisir, and L. de Repentigny. 1997. Oral carriage of Candida albicans in murine AIDS. Infect. Immun. 65:661-667.
16. Elbim, C., M. H. Prevot, F. Bouscarat, E. Franzini, S. Chollet-Martin, J. Hakim, and M. A. Gougerot-Pocidalo. 1994. Polymorphonuclear neutrophils from human immunodeficiency virus-infected patients show enhanced activation, diminished fMLP-induced L-selectin shedding, and an impaired oxidative burst after cytokine priming. Blood 84:2759-2766.
17. Ellis, M., S. Gupta, S. Galant, S. Hakim, C. VandeVen, C. Toy, and M. S. Cairo. 1988. Impaired neutrophil function in patients with AIDS or AIDS-related complex: a comprehensive evaluation. J. Infect. Dis. 158:1268-1276.
18. Eversole, L. R., P. A. Reichart, G. Ficarra, A. Schmidt-Westhausen, P. Romagnoli, and N. Pimpinelli. 1997. Oral keratinocyte immune responses in HIV-associated candidiasis. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 84:372-380.
19. + T lymphocytes in recovery from oropharyngeal candidiasis. Infect. Immun. 70:724-731.
20. Farah, C. S., S. Elahi, G. Pang, T. Gotjamanos, G. J. Seymour, R. L. Clancy, and R. B. Ashman. 2001. T cells augment monocyte and neutrophil function in host resistance against oropharyngeal candidiasis. Infect. Immun. 69:6110-6118.
21. Fattorossi, A., R. Nisini, J. G. Pizzolo, and R. D'Amelio. 1989. New, simple flow cytometry technique to discriminate between internalized and membrane-bound particles in phagocytosis. Cytometry 10:320-325.
22. Fidel, P. L., Jr., M. Barousse, T. Espinosa, M. Ficarra, J. Sturtevant, D. H. Martin, A. J. Quayle, and K. Dunlap. 2004. An intravaginal live Candida challenge in humans leads to new hypotheses for the immunopathogenesis of vulvovaginal candidiasis. Infect. Immun. 72:2939-2946.
23. Fleming, T. J., M. L. Fleming, and T. R. Malek. 1993. Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family. J. Immunol. 151:2399-2408.
24. Fung-Leung, W. P., M. W. Schilham, A. Rahemtulla, T. M. Kundig, M. Vollenweider, J. Potter, W. van Ewijk, and T. W. Mak. 1991. CD8 is needed for development of cytotoxic T cells but not helper T cells. Cell 65:443-449.
25. Gabrilovich, D. I., A. T. Kozhich, Z. K. Suvorova, V. S. Ivanov, S. A. Moshnikov, L. D. Chikin, O. V. Kolezonkova, and V. V. Pokrovsky. 1991. Influence of HIV antigens on functional activity of neutrophilic granulocytes. Scand. J. Immunol. 33:549-552.
26. Hanna, Z., D. G. Kay, M. Cool, S. Jothy, N. Rebai, and P. Jolicoeur. 1998. Transgenic mice expressing human immunodeficiency virus type 1 in immune cells develop a severe AIDS-like disease. J. Virol. 72:121-132.
27. Hanna, Z., D. G. Kay, N. Rebai, A. Guimond, S. Jothy, and P. Jolicoeur. 1998. Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice. Cell 95:163-175.
28. Herbein, G., U. Mahlknecht, F. Batliwalla, P. Gregersen, T. Pappas, J. Butler, W. A. O'Brien, and E. Verdin. 1998. Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4. Nature 395:189-194.
29. Jensen, J., T. Warner, and E. Balish. 1993. Resistance of SCID mice to Candida albicans administered intravenously or colonizing the gut: role of polymorphonuclear leukocytes and macrophages. J Infect. Dis. 167:912-919.
30. Jensen, J., T. Warner, and E. Balish. 1994. The role of phagocytic cells in resistance to disseminated candidiasis in granulocytopenic mice. J Infect. Dis. 170:900-905.
31. Kennedy, M. J., and P. A. Volz. 1985. Ecology of Candida albicans gut colonization: inhibition of Candida adhesion, colonization, and dissemination from the gastrointestinal tract by bacterial antagonism. Infect. Immun. 49:654-663.
32. Martins, M. D., M. Lozano-Chiu, and J. H. Rex. 1998. Declining rates of oropharyngeal candidiasis and carriage of Candida albicans associated with trends toward reduced rates of carriage of fluconazole-resistant C. albicans in human immunodeficiency virus-infected patients. Clin. Infect. Dis. 27:1291-1294.
33. Mastroianni, C. M., G. d'Ettorre, G. Forcina, M. Lichtner, F. Mengoni, C. D'Agostino, A. Corpolongo, A. P. Massetti, and V. Vullo. 2000. Interleukin-15 enhances neutrophil functional activity in patients with human immunodeficiency virus infection. Blood 96:1979-1984.
34. Munoz, J. F., S. Salmen, L. R. Berrueta, M. P. Carlos, J. A. Cova, J. H. Donis, M. R. Hernandez, and J. V. Torres. 1999. Effect of human immunodeficiency virus type 1 on intracellular activation and superoxide production by neutrophils. J. Infect. Dis. 180:206-210.
35. Myers, T. A., J. E. Leigh, A. R. Arribas, S. Hager, R. Clark, E. Lilly, and P. L. Fidel, Jr. 2003. Immunohistochemical evaluation of T cells in oral lesions from human immunodeficiency virus-positive persons with oropharyngeal candidiasis. Infect. Immun. 71:956-963.
36. Nagendra, S., and A. J. Schlueter. 2004. Absence of cross-reactivity between murine Ly-6C and Ly-6G. Cytometry 58A:195-200.
37. Pitrak, D. L., P. M. Bak, P. DeMarais, R. M. Novak, and B. R. Andersen. 1993. Depressed neutrophil superoxide production in human immunodeficiency virus infection. J. Infect. Dis. 167:1406-1410.
38. Quaranta, M. G., B. Mattioli, L. Giordani, and M. Viora. 2004. HIV-1 Nef equips dendritic cells to reduce survival and function of CD8+ T cells: a mechanism of immune evasion. FASEB J. 18:1459-1461.
39. Reichart, P. A., H. P. Philipsen, A. Schmidt-Westhausen, and L. P. Samaranayake. 1995. Pseudomembranous oral candidiasis in HIV infection: ultrastructural findings. J. Oral Pathol. Med. 24:276-281.
40. Reichart, P. A., L. P. Samaranayake, and H. P. Philipsen. 2000. Pathology and clinical correlates in oral candidiasis and its variants: a review. Oral Dis. 6:85-91.
41. Roilides, E., H. Katsifa, S. Tsaparidou, T. Stergiopoulou, C. Panteliadis, and T. J. Walsh. 2000. Interleukin 10 suppresses phagocytic and antihyphal activities of human neutrophils. Cytokine 12:379-387.
42. Romagnoli, P., N. Pimpinelli, M. Mori, P. A. Reichart, L. R. Eversole, and G. Ficarra. 1997. Immunocompetent cells in oral candidiasis of HIV-infected patients: an immunohistochemical and electron microscopical study. Oral Dis. 3:99-105.
43. Romani, L. 1999. Immunity to Candida albicans: Th1, Th2 cells and beyond. Curr. Opin. Microbiol. 2:363-367.
44. Romani, L. 2002. Immunology of invasive candidiasis, p. 223-241. In R. Calderone (ed.), Candida and candidiasis. ASM Press, Washington, D.C.
45. Ryder, M. I., J. R. Winkler, and R. N. Weinreb. 1988. Elevated phagocytosis, oxidative burst, and F-actin formation in PMNs from individuals with intraoral manifestations of HIV infection. J. Acquir. Immune Defic. Syndr. 1:346-353.
46. Samaranayake, L. P. 1992. Oral mycoses in HIV infection. Oral Surg. Oral Med. Oral Pathol. 73:171-180.
47. Saresella, M., K. Roda, L. Speciale, D. Taramelli, E. Mendozzi, F. Guerini, and P. Ferrante. 1997. A rapid evaluation of phagocytosis and killing of Candida albicans by CD13+ leukocytes. J. Immunol. Methods 210:227-234.
48. Tascini, C., F. Baldelli, C. Monari, C. Retini, D. Pietrella, D. Francisci, F. Bistoni, and A. Vecchiarelli. 1996. Inhibition of fungicidal activity of polymorphonuclear leukocytes from HIV-infected patients by interleukin (IL)-4 and IL-10. AIDS 10:477-483.
49. Wenisch, C., B. Parschalk, K. Zedwitz-Liebenstein, W. Graninger, and A. Rieger. 1996. Dysregulation of the polymorphonuclear leukocyte-Candida spp. interaction in HIV-positive patients. AIDS 10:983-987.