Campylobacter jejuni infection and virulence-associated genes in children with moderate to severe diarrhoea admitted to emergency rooms in northeastern Brazil

Journal of Medical Microbiology

Volumn 61, Issue 4, 2012, Pages 507-513

  Quetz, da Josiane S ^a   Lima, Ila F N ^a   Havt, Alexandre ^a   Prata, Mara M G ^a   Cavalcante, Paloma A ^a   Medeiros, Pedro H Q S ^a   Cid, David A C ^a   Moraes, Milena L ^a   Rey, Luís Carlos ^a   Soares, Alberto M ^a   Mota, Rosa M S ^a   Weigl, Bernhard H ^b   Guerrant, Richard L ^c   Lima, Aldo A M ^a  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^b University of Virginia ^*

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; GENOMIC DNA; OLIGONUCLEOTIDE;

ABDOMINAL PAIN; ADOLESCENT; ARTICLE; BACTERIAL GENETICS; BACTERIAL VIRULENCE; BACTERIUM DETECTION; BRAZIL; CAMPYLOBACTER COLI; CAMPYLOBACTER ENTERITIS; CAMPYLOBACTER JEJUNI; CHILD; CHILDHOOD DISEASE; CONTROLLED STUDY; DIARRHEA; DISEASE SEVERITY; DNA EXTRACTION; EMERGENCY WARD; ENZYME LINKED IMMUNOSORBENT ASSAY; FECES ANALYSIS; FEMALE; FEVER; GENE AMPLIFICATION; HOSPITAL ADMISSION; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; MULTIPLEX POLYMERASE CHAIN REACTION; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; QUESTIONNAIRE; SCHOOL CHILD; VOMITING;

ADOLESCENT; BACTERIAL PROTEINS; BRAZIL; CAMPYLOBACTER INFECTIONS; CAMPYLOBACTER JEJUNI; CHILD; CHILD, PRESCHOOL; DIARRHEA; EMERGENCY SERVICE, HOSPITAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION REGULATION, BACTERIAL; HUMANS; INFANT; MALE; VIRULENCE;

EID: 84858127410     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.040600-0     Document Type: Article

References (49)

1. Al-Mahmeed, A., Senok, A. C., Ismaeel, A. Y., Bindayna, K. M., Tabbara, K. S. & Botta, G. A. (2006). Clinical relevance of virulence genes in Campylobacter jejuni isolates in Bahrain. J Med Microbiol 55, 839-843.
2. Allos, B. M. (2001). Campylobacter jejuni infections: update on emerging issues and trends. Clin Infect Dis 32, 1201-1206.
3. Amieva, M. R. (2005). Important bacterial gastrointestinal pathogens in children: a pathogenesis perspective. Pediatr Clin North Am 52, 749-777, vi.
4. Andrzejewska, M., Klawe, J. J., Szczepańska, B. & Spica, D. (2011). Occurrence of virulence genes among Campylobacter jejuni and Campylobacter coli isolates from domestic animals and children. Pol J Vet Sci 14, 207-211.
5. Bacon, D. J., Alm, R. A., Burr, D. H., Hu, L., Kopecko, D. J., Ewing, C. P., Trust, T. J. & Guerry, P. (2000). Involvement of a plasmid in virulence of Campylobacter jejuni 81-176. Infect Immun 68, 4384-4390.
6. Bacon, D. J., Alm, R. A., Hu, L., Hickey, T. E., Ewing, C. P., Batchelor, R. A., Trust, T. J. & Guerry, P. (2002). DNA sequence and mutational analyses of the pVir plasmid of Campylobacter jejuni 81-176. Infect Immun 70, 6242-6250.
7. Beltinger, J., del Buono, J., Skelly, M. M., Thornley, J., Spiller, R. C., Stack, W. A. & Hawkey, C. J. (2008). Disruption of colonic barrier function and induction of mediator release by strains of Campylobacter jejuni that invade epithelial cells. World J Gastroenterol 14, 7345-7352.
8. Brandal, L. T., Lindstedt, B. A., Aas, L., Stavnes, T. L., Lassen, J. & Kapperud, G. (2007). Octaplex PCR and fluorescence-based capillary electrophoresis for identification of human diarrheagenic Escherichia coli and Shigella spp. J Microbiol Methods 68, 331-341.
9. Brás, A. M., Chatterjee, S., Wren, B. W., Newell, D. G. & Ketley, J. M. (1999). A novel Campylobacter jejuni two-component regulatory system important for temperature-dependent growth and colonization. J Bacteriol 181, 3298-3302.
10. da Silva Quetz, J., Lima, I. F., Havt, A., de Carvalho, E. B., Lima, N. L., Soares, A. M., Mota, R. M., Guerrant, R. L. & Lima, A. A. (2010). Campylobacter jejuni and Campylobacter coli in children from communities in Northeastern Brazil: molecular detection and relation to nutritional status. Diagn Microbiol Infect Dis 67, 220-227.
11. Dasti, J. I., Tareen, A. M., Lugert, R., Zautner, A. E. & Gross, U. (2010). Campylobacter jejuni: a brief overview on pathogenicity-associated factors and disease-mediating mechanisms. Int J Med Microbiol 300, 205-211.
12. Datta, S., Niwa, H. & Itoh, K. (2003). Prevalence of 11 pathogenic genes of Campylobacter jejuni by PCR in strains isolated from humans, poultry meat and broiler and bovine faeces. J Med Microbiol 52, 345-348.
13. Dediste, A., Vandenberg, O., Vlaes, L., Ebraert, A., Douat, N., Bahwere, P. & Butzler, J. P. (2003). Evaluation of the ProSpecT microplate assay for detection of Campylobacter: a routine laboratory perspective. Clin Microbiol Infect 9, 1085-1090.
14. Fernández, H. (2011). [Campylobacter and campylobacteriosis: a view from South America]. Rev Peru Med Exp Salud Publica 28, 121-127 (in Spanish).
15. Fernández, H., Vera, F., Villanueva, M. P. & García, A. (2008). Occurrence of Campylobacter species in healthy well-nourished and malnourished children. Braz J Microbiol 39, 56-58.
16. Fitzgerald, C., Helsel, L. O., Nicholson, M. A., Olsen, S. J., Swerdlow, D. L., Flahart, R., Sexton, J. & Fields, P. I. (2001). Evaluation of methods for subtyping Campylobacter jejuni during an outbreak involving a food handler. J Clin Microbiol 39, 2386-2390.
17. Fouts, D. E., Mongodin, E. F., Mandrell, R. E., Miller, W. G., Rasko, D. A., Ravel, J., Brinkac, L. M., DeBoy, R. T., Parker, C. T. & other authors (2005). Major structural differences and novel potential virulence mechanisms from the genomes of multiple Campylobacter species. PLoS Biol 3, e15.
18. Hamidian, M., Sanaei, M., Bolfion, M., Dabiri, H., Zali, M. R. & Walther-Rasmussen, J. (2011). Prevalence of putative virulence markers in Campylobacter jejuni and Campylobacter coli isolated from hospitalized children, raw chicken, and raw beef in Tehran, Iran. Can J Microbiol 57, 143-148.
19. Inglis, G. D., Boras, V. F. & Houde, A. (2011). Enteric campylobacteria and RNA viruses associated with healthy and diarrheic humans in the Chinook health region of Southwestern Alberta, Canada. J Clin Microbiol 49, 209-219.
20. Ivanova, K., Marina, M., Petrov, P. & Kantardjiev, T. (2010). Campylobacteriosis and other bacterial gastrointestinal diseases in Sofia, Bulgaria for the period 1987-2008. Euro Surveill 15, 19474.
21. Jafari, F., Garcia-Gil, L. J., Salmanzadeh-Ahrabi, S., Shokrzadeh, L., Aslani, M. M., Pourhoseingholi, M. A., Derakhshan, F. & Zali, M. R. (2009). Diagnosis and prevalence of enteropathogenic bacteria in children less than 5 years of age with acute diarrhea in Tehran children's hospitals. J Infect 58, 21-27.
22. Kaboré, H., Michel, P., Levallois, P., Déry, P., Payment, P. & Lebel, G. (2010). A descriptive review of selected nonviral enteric illnesses reported in children in Quebec between 1999 and 2006. Can J Infect Dis Med Microbiol 21, e92-e98.
23. Konkel, M. E., Kim, B. J., Klena, J. D., Young, C. R. & Ziprin, R. (1998). Characterization of the thermal stress response of Campylobacter jejuni. Infect Immun 66, 3666-3672.
24. Konkel, M. E., Kim, B. J., Rivera-Amill, V. & Garvis, S. G. (1999). Bacterial secreted proteins are required for the internalization of Campylobacter jejuni into cultured mammalian cells. Mol Microbiol 32, 691-701.
25. Konkel, M. E., Klena, J. D., Rivera-Amill, V., Monteville, M. R., Biswas, D., Raphael, B. & Mickelson, J. (2004). Secretion of virulence proteins from Campylobacter jejuni is dependent on a functional flagellar export apparatus. J Bacteriol 186, 3296-3303.
26. Lara-Tejero, M. & Galán, J. E. (2001). CdtA, CdtB, and CdtC form a tripartite complex that is required for cytolethal distending toxin activity. Infect Immun 69, 4358-4365.
27. Louwen, R. P. L., van Belkum, A., Wagenaar, J. A., Doorduyn, Y., Achterberg, R. & Endtz, H. P. (2006). Lack of association between the presence of the pVir plasmid and bloody diarrhea in Campylobacter jejuni enteritis. J Clin Microbiol 44, 1867-1868.
28. Maher, M., Finnegan, C., Collins, E., Ward, B., Carroll, C. & Cormican, M. (2003). Evaluation of culture methods and a DNA probe-based PCR assay for detection of Campylobacter species in clinical specimens of feces. J Clin Microbiol 41, 2980-2986.
29. Mendes, E. N., Queiroz, D. M. M., Cisalpino, E. O., Peres, J. N., Penna, F., Figueiredo-Filho, P. P. (1987). Occurrence of Campylobacter jejuni in children with and without diarrhea in Belo Horizonte. Rev Microbiol Soc Bras Med 18, 25-30.
30. Moreno, A. C., Filho, A. F., Gomes, T. A., Ramos, S. T., Montemor, L. P., Tavares, V. C., Filho, L. S., Irino, K. & Martinez, M. B. (2010). Etiology of childhood diarrhea in the northeast of Brazil: significant emergent diarrheal pathogens. Diagn Microbiol Infect Dis 66, 50-57.
31. Mortensen, N. P., Schiellerup, P., Boisen, N., Klein, B. M., Locht, H., Abuoun, M., Newell, D. & Krogfelt, K. A. (2011). The role of Campylobacter jejuni cytolethal distending toxin in gastroenteritis: toxin detection, antibody production, and clinical outcome. APMIS 119, 626-634.
32. Podewils, L. J., Mintz, E. D., Nataro, J. P. & Parashar, U. D. (2004). Acute, infectious diarrhea among children in developing countries. Semin Pediatr Infect Dis 15, 155-168.
33. Ripabelli, G., Tamburro, M., Minelli, F., Leone, A. & Sammarco, M. L. (2010). Prevalence of virulence-associated genes and cytolethal distending toxin production in Campylobacter spp. isolated in Italy. Comp Immunol Microbiol Infect Dis 33, 355-364.
34. Sherman, P. M., Ossa, J. C. & Wine, E. (2010). Bacterial infections: new and emerging enteric pathogens. Curr Opin Gastroenterol 26, 1-4.
35. Singh, H., Rathore, R. S., Singh, S. & Cheema, P. S. (2011). Comparative analysis of cultural isolation and PCR based assay for detection of Campylobacter jejuni in food and faecal samples. Braz J Microbiol 42, 181-186.
36. Sinha, S., Prasad, K. N., Pradhan, S., Jain, D. & Jha, S. (2004). Detection of preceding Campylobacter jejuni infection by polymerase chain reaction in patients with Guillain-Barré syndrome. Trans R Soc Trop Med Hyg 98, 342-346.
37. Soofi, S. B., Habib, M. A., von Seidlein, L., Khan, M. J., Muhammad, S., Bhutto, N., Khan, M. I., Rasool, S., Zafar, A. & other authors (2011). A comparison of disease caused by Shigella and Campylobacter species: 24 months community based surveillance in 4 slums of Karachi, Pakistan. J Infect Public Health 4, 12-21.
38. Talukder, K. A., Aslam, M., Islam, Z., Azmi, I. J., Dutta, D. K., Hossain, S., Nur-E-Kamal, A., Nair, G. B., Cravioto, A. & other authors (2008). Prevalence of virulence genes and cytolethal distending toxin production in Campylobacter jejuni isolates from diarrheal patients in Bangladesh. J Clin Microbiol 46, 1485-1488.
39. Tam, C. C., O'Brien, S. J., Adak, G. K., Meakins, S. M. & Frost, J. A. (2003). Campylobacter coli - an important foodborne pathogen. J Infect 47, 28-32.
40. Tracz, D. M., Keelan, M., Ahmed-Bentley, J., Gibreel, A., Kowalewska-Grochowska, K. & Taylor, D. E. (2005). pVir and bloody diarrhea in Campylobacter jejuni enteritis. Emerg Infect Dis 11, 838-843.
41. Vu Nguyen, T., Le Van, P., Le Huy, C., Nguyen Gia, K. & Weintraub, A. (2006). Etiology and epidemiology of diarrhea in children in Hanoi, Vietnam. Int J Infect Dis 10, 298-308.
42. Wang, G., Clark, C. G. & Rodgers, F. G. (2002). Detection in Escherichia coli of the genes encoding the major virulence factors, the genes defining the O157:H7 serotype, and components of the type 2 Shiga toxin family by multiplex PCR. J Clin Microbiol 40, 3613-3619.
43. Wang, S. C., Chang, L. Y., Hsueh, P. R., Lu, C. Y., Lee, P. I., Shao, P. L., Hsieh, Y. C., Yen, F. P., Lee, C. Y. & Huang, L. M. (2008). Campylobacter enteritis in children in northern Taiwan - a 7-year experience. J Microbiol Immunol Infect 41, 408-413.
44. Wassenaar, T. M. (1997). Toxin production by Campylobacter spp. Clin Microbiol Rev 10, 466-476.
45. Weigl, B. H., Gerdes, J., Tarr, P., Yager, P., Dillman, L., Peck, R., Ranachandran, S., Lemba, M., Kokoris, M. & other authors (2006). Fully integrated multiplexed lab-on-a-card assay for enteric pathogens. Proc SPIE 6112, 611202.
46. Yager, P., Edwards, T., Fu, E., Helton, K., Nelson, K., Tam, M. R. & Weigl, B. H. (2006). Microfluidic diagnostic technologies for global public health. Nature 442, 412-418.
47. Yamasaki, S., Asakura, M., Tsukamoto, T., Faruque, S. M., Deb, R. & Ramamurthy, T. (2006). Cytolethal distending toxin (CDT): genetic diversity, structure and role in diarrheal disease. Toxin Rev 25, 61-88.
48. Young, V. B. & Schauer, D. B. (2000). Cytolethal distending toxin: a bacterial toxin which disrupts the eukaryotic cell cycle. Chem Res Toxicol 13, 936-939.
49. Ziprin, R. L., Young, C. R., Byrd, J. A., Stanker, L. H., Hume, M. E., Gray, S. A., Kim, B. J. & Konkel, M. E. (2001). Role of Campylobacter jejuni potential virulence genes in cecal colonization. Avian Dis 45, 549-557.