Deep brain stimulation reveals a dissociation of consummatory and motivated behaviour in the medial and lateral nucleus accumbens shell of the rat

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  van der Plasse, Geoffrey ^a   Schrama, Regina ^a   van Seters, Sebastiaan P ^a   Vanderschuren, Louk J M J ^a,b   Westenberg, Herman G M ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

SUCROSE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; APPETITE; ARTICLE; BRAIN DEPTH STIMULATION; BRAIN REGION; CONTROLLED STUDY; EATING DISORDER; FEEDING BEHAVIOR; FOOD INTAKE; FOOD PREFERENCE; FUNCTIONAL ANATOMY; LATERAL NUCLEUS ACCUMBENS; MALE; MEDIAL NUCLEUS ACCUMBENS; MOTIVATION; NONHUMAN; NUCLEUS ACCUMBENS; RAT; REINFORCEMENT; REWARD; ANIMAL; COMPARATIVE STUDY; ELECTROSTIMULATION; HISTOLOGY; INSTRUMENTAL CONDITIONING; METHODOLOGY; PHYSIOLOGY; WISTAR RAT;

RATTUS;

ANIMALS; APPETITIVE BEHAVIOR; CONDITIONING, OPERANT; CONSUMMATORY BEHAVIOR; DEEP BRAIN STIMULATION; ELECTRIC STIMULATION; FEEDING BEHAVIOR; HISTOLOGICAL TECHNIQUES; MALE; MOTIVATION; NUCLEUS ACCUMBENS; RATS; RATS, WISTAR;

EID: 84858121271     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033455     Document Type: Article

References (46)

1. Ward HE, Hwynn N, Okun MS, (2010) Update on deep brain stimulation for neuropsychiatric disorders. Neurobiology of Disease 38: 346-353.
2. Benabid AL, Chabardes S, Mitrofanis J, Pollak P, (2009) Deep brain stimulation of the subthalamic nucleus for the treatment of Parkinson's disease. Lancet Neurology 8: 67-81.
3. Denys D, Mantione M, Figee M, van den Munckhof P, Koerselman F, et al. (2010) Deep Brain Stimulation of the Nucleus Accumbens for Treatment-Refractory Obsessive-Compulsive Disorder. Archives of General Psychiatry 67: 1061-1068.
4. Greenberg BD, Gabriels LA, Malone DA Jr, Rezai AR, Friehs GM, et al. (2010) Deep brain stimulation of the ventral internal capsule/ventral striatum for obsessive-compulsive disorder: worldwide experience. Mol Psychiatry 15: 64-79.
5. Schlaepfer TE, Cohen MX, Frick C, Kosel M, Brodesser D, et al. (2008) Deep brain stimulation to reward circuitry alleviates anhedonia in refractory major depression. Neuropsychopharmacology 33: 368-377.
6. Blomstedt P, Sjoberg RL, Hansson M, Bodlund O, Hariz MI, (2011) Deep brain stimulation in the treatment of depression. Acta Psychiatrica Scandinavica 123: 4-11.
7. Hariz MI, Robertson MM, (2010) Gilles de la Tourette syndrome and deep brain stimulation. European Journal of Neuroscience 32: 1128-1134.
8. Lega BC, Halpern CH, Jaggi JL, Baltuch GH, (2010) Deep brain stimulation in the treatment of refractory epilepsy: Update on current data and future directions. Neurobiology of Disease 38: 354-360.
9. Hall W, Carter A, (2011) Is deep brain stimulation a prospective "cure" for addiction? F1000 Med Rep 3: 4.
10. Halpern CH, Wolf JA, Bale TL, Stunkard AJ, Danish SF, et al. (2008) Deep brain stimulation in the treatment of obesity. Journal of Neurosurgery 109: 625-634.
11. Cardinal RN, Parkinson JA, Hall J, Everitt BJ, (2002) Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex. Neurosci Biobehav Rev 26: 321-352.
12. Voorn P, Vanderschuren LJMJ, Groenewegen HJ, Robbins TW, Pennartz CMA, (2004) Putting a spin on the dorsal-ventral divide of the striatum. Trends in Neurosciences 27: 468-474.
13. Kelley AE, Baldo BA, Pratt WE, Will MJ, (2005) Corticostriatal-hypothalamic circuitry and food motivation: Integration of energy, action and reward. Physiology & Behavior 86: 773-795.
14. Meredith GE, Baldo BA, Andrezjewski ME, Kelley AE, (2008) The structural basis for mapping behavior onto the ventral striatum and its subdivisions. Brain Structure & Function 213: 17-27.
15. Yin HH, Ostlund SB, Balleine BW, (2008) Reward-guided learning beyond dopamine in the nucleus accumbens: the integrative functions of cortico-basal ganglia networks. Eur J Neurosci 28: 1437-1448.
16. Zahm DS, Brog JS, (1992) On the Significance of Subterritories in the Accumbens Part of the Rat Ventral Striatum. Neuroscience 50: 751-767.
17. Groenewegen HJ, Wright CI, Beijer AVJ, Voorn P, (1999) Convergence and segregation of ventral striatal inputs and outputs. Advancing from the Ventral Striatum to the Extended Amygdala 877: 49-63.
18. Parkinson JA, Olmstead MC, Burns LH, Robbins TW, Everitt BJ, (1999) Dissociation in effects of lesions of the nucleus accumbens core and shell on appetitive Pavlovian approach behavior and the potentiation of conditioned reinforcement and locomotor activity by D-Amphetamine. Journal of Neuroscience 19: 2401-2411.
19. Ambroggi F, Ghazizadeh A, Nicola SM, Fields HL, (2011) Roles of Nucleus Accumbens Core and Shell in Incentive-Cue Responding and Behavioral Inhibition. Journal of Neuroscience 31: 6820-6830.
20. Shiflett MW, Balleine BW, (2010) At the limbic-motor interface: disconnection of basolateral amygdala from nucleus accumbens core and shell reveals dissociable components of incentive motivation. European Journal of Neuroscience 32: 1735-1743.
21. Corbit LH, Balleine BW, (2011) The general and outcome-specific forms of pavlovian-instrumental transfer are differentially mediated by the nucleus accumbens core and shell. J Neurosci 31: 11786-11794.
22. Corbit LH, Muir JL, Balleine BW, (2001) The role of the nucleus accumbens in instrumental conditioning: Evidence of a functional dissociation between accumbens core and shell. Journal of Neuroscience 21: 3251-3260.
23. Smith KS, Berridge KC, (2007) Opioid limbic circuit for reward: Interaction between hedonic hotspots of nucleus accumbens and ventral pallidum. Journal of Neuroscience 27: 1594-1605.
24. Kelley AE, Swanson CJ, (1997) Feeding induced by blockade of AMPA and kainate receptors within the ventral striatum: a microinfusion mapping study. Behavioural Brain Research 89: 107-113.
25. Stratford TR, Kelley AE, (1997) GABA in the nucleus accumbens shell participates in the central regulation of feeding behavior. Journal of Neuroscience 17: 4434-4440.
26. Zhang M, Balmadrid C, Kelley AE, (2003) Nucleus accumbens opioid, GABAergic, and dopaminergic modulation of palatable food motivation: Contrasting effects revealed by a progressive ratio study in the rat. Behavioral Neuroscience 117: 202-211.
27. Stratford TR, Kelley AE, (1999) Evidence of a functional relationship between the nucleus accumbens shell and lateral hypothalamus subserving the control of feeding behavior. Journal of Neuroscience 19: 11040-11048.
28. Sesia T, Temel Y, Lim LW, Blokland A, Steinbusch HWM, et al. (2008) Deep brain stimulation of the nucleus accumbens core and shell: Opposite effects on impulsive action. Experimental Neurology 214: 135-139.
29. Vassoler FM, Schmidt HD, Gerard ME, Famous KR, Ciraulo DA, et al. (2008) Deep brain stimulation of the nucleus accumbens shell attenuates cocaine priming-induced reinstatement of drug seeking in rats. Journal of Neuroscience 28: 8735-8739.
30. Hodos W, (1961) Progressive ratio as a measure of reward strength. Science 134: 943-944.
31. Richardson NR, Roberts DCS, (1996) Progressive ratio schedules in drug self-administration studies in rats: A method to evaluate reinforcing efficacy. Journal of Neuroscience Methods 66: 1-11.
32. Wang SH, Zhang ZJ, Guo YJ, Zhou H, Teng GJ, et al. (2009) Anhedonia and activity deficits in rats: impact of post-stroke depression. Journal of Psychopharmacology 23: 295-304.
33. Paxinos G, Watson C, (1998) The brain in stereotaxic coordinates Academic, San Diego.
34. Basso AM, Kelley AE, (1999) Feeding induced by GABA(A) receptor stimulation within the nucleus accumbens shell: Regional mapping and characterization of macronutrient and taste preference. Behavioral Neuroscience 113: 324-336.
35. Kandov Y, Israel Y, Kest A, Dostova I, Verasammy J, et al. (2006) GABA receptor subtype antagonists in the nucleus accumbens shell and ventral tegmental area differentially alter feeding responses induced by deprivation, glucoprivation and lipoprivation in rats. Brain Research 1082: 86-97.
36. Wirtshafter D, Stratford TR, (2010) Evidence for motivational effects elicited by activation of GABA-A or dopamine receptors in the nucleus accumbens shell. Pharmacology Biochemistry and Behavior 96: 342-346.
37. Berridge KC, Robinson TE, Aldridge JW, (2009) Dissecting components of reward: 'liking', 'wanting', and learning. Curr Opin Pharmacol 9: 65-73.
38. Faure A, Richard JM, Berridge KC, (2010) Desire and Dread from the Nucleus Accumbens: Cortical Glutamate and Subcortical GABA Differentially Generate Motivation and Hedonic Impact in the Rat. Plos One 5 (6): e11223.
39. Bittar RG, (2006) Neuromodulation for movement disorders. Journal of Clinical Neuroscience 13: 315-318.
40. Maldonado-Irizarry CS, Kelley AE, (1995) Excitotoxic Lesions of the Core and Shell Subregions of the Nucleus-Accumbens Differentially Disrupt Body-Weight Regulation and Motor-Activity in Rat. Brain Research Bulletin 38: 551-559.
41. Pecina S, Smith KS, Berridge KC, (2006) Hedonic hot spots in the brain. Neuroscientist 12: 500-511.
42. Kringelbach ML, Jenkinson N, Owen SLF, Aziz TZ, (2007) Translational principles of deep brain stimulation. Nature Reviews Neuroscience 8: 623-635.
43. Lammel S, Ion DI, Roeper J, Malenka RC, (2011) Projection-Specific Modulation of Dopamine Neuron Synapses by Aversive and Rewarding Stimuli. Neuron 70: 855-862.
44. De Wit H, Wise RA, (1977) Blockade of cocaine reinforcement in rats with the dopamine receptor blocker pimozide, but not with the noradrenergic blockers phentolamine or phenoxybenzamine. Canadian Journal of Psychology 31: 195-203.
45. Roberts DCS, Loh EA, Vickers G, (1989) Self-administration of cocaine on a progressive ratio schedule in rats: dose-response relationship and effect of haloperidol pretreatment. Psychopharmacology 97: 535-538.
46. Veeneman MMJ, van Ast M, Broekhoven MH, Limpens JHW, Vanderschuren LJMJ, (2011) Seeking-taking chain schedules of self-administration to assess the motivational properties of cocaine and sucrose: effects of reward size, reward omission, and alpha-flupenthixol. Psychopharmacology doi:10.1007/s00213-011-2525-8.