β-Amyloid burden in the temporal neocortex is related to hippocampal atrophy in elderly subjects without dementia

Neurology

Volumn 74, Issue 2, 2010, Pages 121-127

  Bourgeat, P ^a   Chetelat G ^b,c   Villemagne, V L ^b,d,e   Fripp, J ^a   Raniga, P ^a   Pike, K ^b,d   Acosta, O ^a   Szoeke, C ^a   Ourselin, S ^a   Ames, D ^g   Ellis, K A ^e   Martins, R N ^h   Masters, C L ^d,e   Rowe, C C ^b,e   Salvado, O ^f  

^a ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^b AUSTIN HEALTH   (Australia)

^c UNIVERSITÉ DE CAEN   (France)

^d Mental Health Research Institute

^e UNIVERSITY OF MELBOURNE   (Australia)

^f UNIVERSITY COLLEGE LONDON   (United Kingdom)

^g NATIONAL AGEING RESEARCH INSTITUTE   (Australia)

^h EDITH COWAN UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; CARBON 11; PITTSBURGH COMPOUND B CARBON 11; TRACER; UNCLASSIFIED DRUG;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN ATROPHY; CONTROLLED STUDY; DEMENTIA; FEMALE; HIPPOCAMPUS; HUMAN; MAJOR CLINICAL STUDY; MALE; MILD COGNITIVE IMPAIRMENT; NEOCORTEX; NERVE CELL DEGENERATION; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; TEMPORAL CORTEX; VOLUMETRY;

EID: 75649106499     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0b013e3181c918b5     Document Type: Article

References (40)

1. Ikonomovic MD, Klunk WE, Abrahamson EE, et al. Postmortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease. Brain 2008;131: 1630-1645.
2. Rowe C, Ng S, Ackermann U, et al. Imaging beta-amyloid burden in aging and dementia. Neurology 2007;68:1718-1725.
3. Fripp J, Bourgeat P, Acosta O, et al. Appearance modeling of 11C PiB PET images: characterizing amyloid deposition in Alzheimer's disease, mild cognitive impairment and healthy aging. Neuroimage 2008;43:430-439.
4. Jack CR, Lowe VJ, Senjem ML, et al. 11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment. Brain 2008;131:665-680.
5. Baron JC, Chételat G, Desgranges B, et al. In vivo mapping of gray matter loss with voxel-based morphometry in mild Alzheimer's disease. Neuroimage 2001;14:298-309.
6. Fleisher AS, Sun S, Taylor C, et al. Volumetric MRI vs clinical predictors of Alzheimer disease in mild cognitive impairment. Neurology 2008;70:191-199.
7. Gosche KM, Mortimer JA, Smith CD, Markesbery WR, Snowdon DA. Hippocampal volume as an index of Alzheimer neuropathology: findings from the Nun Study. Neurology 2002;58:1476-1482.
8. Chetelat G, Baron JC. Early diagnosis of Alzheimer's disease: contribution of structural neuroimaging. Neuroim-age 2003;18:525-541.
9. Price JL, Morris JC. Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease Ann Neurol 1999;45:358-368.
10. Frisoni GB, Lorenzi M, Caroli A, Kemppainen N, Någren K, Rinne JO. In vivo mapping of amyloid toxicity in Alzheimer disease. Neurology 2009;72:1504-1511.
11. Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002;297:353-356.
12. Masters CL, Cappai R, Barnham KJ, Villemagne VL. Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics. J Neurochem 2006;97: 1700-1725. (Pubitemid 43873662)
13. Mormino EC, Kluth JT, Madison CM, et al. Episodic memory loss is related to hippocampal-mediated /3-amyloid deposition in elderly subjects. Brain 2009;132: 1310-1323.
14. Ellis KA, Bush AI, Darby D, et al. The Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging: methodology and baseline characteristics of 1112 individuals recruited for a longitudinal study of Alzheimer's disease. Int Psychogeriatr 2009;21:672-687.
15. Folstein MF, Folstein SE, McHugh PR. "Mini-Mental State": a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189-198.
16. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984;34:939-944.
17. Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E. Mild cognitive impairment: clinical characterization and outcome. Arch Neurol 1999;56:303-308. (Pubitemid 29120227)
18. Delis DC, Kramer JH, Kaplan E, Ober BA. CVLT-II: California Verbal Learning Test Second Edition Adult Version. San Antonio: The Psychological Corporation; 2000.
19. Meyers JE, Meyers KR. Rey Complex Figure Test and Recognition Trial. Odessa: Psychological Assessment Resources Inc.; 1995.
20. Pike K, Savage G, Villemagne V, et al. β-Amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease. Brain 2007;130:2837-2844.
21. Acosta O, Bourgeat P, Zuluaga MA, et al. Automated voxel-based 3D cortical thickness measurement in a combined Lagrangian-Eulerian PDE approach using partial volume maps. Med Image Anal 2009;13:730-743.
22. Ourselin S, Roche A, Subsol G, Pennec X, Ayache N. Reconstructing a 3D structure from serial histological sections. Image Vision Comput 2001;19:25-31.
23. Vercauteren T, Pennec X, Perchant A, Ayache N. Diffeo-morphic demons: efficient non-parametric image registration. Neuroimage 2009;45:S61-S72.
24. Müller-Gartner HW, Links JM, Prince JL, et al. Measurement of radiotracer concentration in brain gray matter using positron emission tomography: MRI-based correction for partial volume effects. J Cereb Blood Flow Metab 1992;12:571-583.
25. Quarantelli M, Berkouk K, Prinster A, et al. Integrated software for the analysis of brain PET/SPECT studies with partial-volume-effect correction. J Nucl Med 2004;45: 192-201.
26. Rousset OG, Ma Y, Wong DF, Evans AC. Pixel-versus region-based partial volume correction in PET. In: Carson RE, Herscovitch P, Daube-Witherspoon M, eds. Quantitative Functional Brain Imaging with Positron Emission Tomography. San Diego: Academic Press; 1998:67-75.
27. Lopresti BJ, Klunk WE, Mathis CA, et al. Simplified quantification of Pittsburgh compound B amyloid imaging PET studies: a comparative analysis. J Nucl Med 2005; 46:1959-1972.
28. Tzourio-Mazoyer N, Landeau B, Papathanassiou D, et al. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage 2002;15:273-289.
29. Villemagne VL, Pike KE, Fodero-Tavoletti MT, et al. Age dependent prevalence of beta-amyloid positive 11C-PIB PET in healthy elderly subjects parallels neuropathology findings. J Nucl Med 2008;49(supp 1):34P. Abstract.
30. Holmes CJ, Hoge R, Collins L, Woods R, Toga AW, Evans AC. Enhancement of MR images using registration for signal averaging. J Comput Assist Tomogr 1998;22: 324-333.
31. Aljabar P, Heckemann RA, Hammers A, Hajnal JV, Rueckert D. Multi-atlas based segmentation of brain images: atlas selection and its effect on accuracy. Neuroimage 2009;46:726-738.
32. Fagan AM, Head D, Shah AR, et al. Decreased cerebrospinal fluid Aβ42 correlates with brain atrophy in cognitively normal elderly. Ann Neurol 2009;65:176-183.
33. Villemagne VL, Pike KE, Darby D, et al. Abeta deposits in older non-demented individuals with cognitive decline are indicative of preclinical Alzheimer's disease. Neuropsycho-logia 2008;46:1688-1697.
34. Jack CR, Lowe VJ, Weigand SD, et al. Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: implications for sequence of pathological events in Alzheimer's disease. Brain 2009;132:1355-1365.
35. Klunk WE, Mathis CA, Price JC, Lopresti BJ, DeKosky ST. Two-year follow-up of amyloid deposition in patients with Alzheimer's disease. Brain 2006;129:2805-2807.
36. Carlson NE, Moore MM, Dame A, et al. Trajectories of brain loss in aging and the development of cognitive impairment. Neurology 2008;70:828-833.
37. Chan D, Janssen JC, Whitwell JL, et al. Change in rates of cerebral atrophy over time in early-onset Alzheimer's disease: longitudinal MRI study. Lancet 2003;362:1121-1122.
38. Miyashita Y. Inferior temporal cortex: where visual perception meets memory. Annu Rev Neurosci 1993;16:245-263.
39. Wang L, Zang Y, He Y, et al. Changes in hippocampal connectivity in the early stages of Alzheimer's disease: evidence from resting state fMRI. Neuroimage 2006;31: 496-504.
40. Smith CD, Chebrolu H, Andersen AH, et al. White matter diffusion alterations in normal women at risk of Alzheimer's disease. Neurobiol Aging Epub 2008 Sep 16.