Effects of aging on hyperalgesia and spinal dynorphin expression in rats with peripheral inflammation

Brain Research

Volumn 999, Issue 1, 2004, Pages 135-141

  Zhang, Rui Xin ^a   Lao, Lixing ^a   Qiao, Jian Tian ^b   Ruda, M A ^c  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b SHANXI MEDICAL UNIVERSITY   (China)

^c NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

Freund's adjuvant; Inflammation; Persistent pain; Serotonin; Spinal cord; Substance P

Indexed keywords

DYNORPHIN;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HYPERALGESIA; INFLAMMATION; MALE; NOCICEPTION; NONHUMAN; PAIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM; UPREGULATION;

EID: 1642513492     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2003.11.042     Document Type: Article

References (46)

1. Akunne H.C., Soliman K.F. Serotonin modulation of pain responsiveness in the aged rat. Pharmacol. Biochem. Behav. 48:1994;411-416.
2. Anderson C.P., Rozovsky I., Stone D.J., Song Y., Lopez L.M., Finch C.E. Aging and increased hypothalamic glial fibrillary acid protein (GFAP) mRNA in F344 female rats. Dissociation of GFAP inducibility from the luteinizing hormone surge. Neuroendocrinology. 76:2002;121-130.
3. Armbrecht H.J., Nemani P.K., Wongsurawat N. Protein phosphorylation: changes with age and age-related diseases. J. Am. Geriatr. Soc. 41:1993;873-879.
4. Besson J.M., Chaouch A. Peripheral and spinal mechanisms of nociception. Physiol. Rev. 67:1987;67-186.
5. Bhaskaran O., Radha E. Monoamine levels and monoamine oxidase activity in different regions of rat brain as a function of age. Mech. Ageing Dev. 23:1983;151-160.
6. Chan S.H.H., Lai Y.Y. Effects of aging on pain response and analgesic efficacy of morphine and cloninide in rats. Exp. Neurol. 75:1982;112-119.
7. Chirgwin J.M., Przybyla A.E., MacDonald R.J., Rutter W.J. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry. 18:1979;5294-5299.
8. Civelli O., Douglass J., Goldstein A., Herbert E. Sequence and expression of the rat prodynorphin gene. Proc. Natl. Acad. Sci. U. S. A. 82:1985;4291-4295.
9. Cizza G., Calogero A.E., Brady L.S., Bagdy G., Bergamini E., Blackman M.R., Chrousos G.P., Gold P.W. Male Fischer 344/N rats show a progressive central impairment of the hypothalamic-pituitary-adrenal axis with advancing age. Endocrinology. 134:1994;1611-1620.
10. Crisp T., Stafinsky J.L., Hoskins D.L., Dayal B., Chinrock K.M., Uram M. Effects of aging on spinal opioid-induced antinociception. Neurobiol. Aging. 15:1994;169-174.
11. Cruse W.L.R., Lovell J.A., Crisp T., Stuesse S.L. Effect of aging on the substance P receptor, NK-1, in the spinal cord of rats with peripheral nerve injury. Somatosens. Motor Res. 18:2001;66-75.
12. Dubner R., Ruda M.A. Activity-dependent neuronal plasticity following tissue injury and inflammation. Trends Neurosci. 15:1992;96-103.
13. Ferrell B.A. Pain management in elderly people. J. Am. Geriatr. Soc. 39:1991;37-64.
14. Flood D.G., Coleman P.D. Neuron numbers and sizes in aging brain: comparison of human, monkey, and rodent data. Neurobiol. Aging. 9:1988;453-463.
15. Gagliese L., Melzack R. Age differences in the response to the formalin test in rats. Neurobiol. Aging. 20:1999;699-707.
16. Gardell L.R., Burgess S.E., Dogrul A., Ossipov M.H., Malan T.P., Lai J., Porreca F. Pronociceptive effects of spinal dynorphin promote cannabinoid-induced pain and antinociceptive tolerance. Pain. 98:2002;79-88.
17. Goicoechea C., Ormazábal M.J., Alfaro M.J., Martín M.I. Age-related changes in nociception, behavior, and monoamine levels in rats. Gen. Pharmacol. 28:1997;331-336.
18. Hamm R.J., Knisely J.S., Watson A. Environmentally-induced analgesia: age-related differences in a hormonally-mediated, nonopioid system. J. Gerontol. 41:1986;336-341.
19. Hargreaves K., Dubner R., Brown F., Flores C., Joris J. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain. 32:1988;77-88.
20. Harkins S.W., Kwentus J., Price D.D. Pain and suffering in the elderly. Bonica J.J. Management of Pain. 1990;552-559 Lea & Febiger, New York.
21. Hess G.D., Joseph J.A., Roth G.S. Effect of age on sensitivity to pain and brain opiate receptors. Neurobiol. Aging. 2:1981;49-55.
22. Hsu S.M., Raind L., Fanger H. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase technique. A comparison between ABC and unlabeled antibody (PAP) procedures. J. Histochem. Cytochem. 29:1981;577-580.
23. Iadarola M.J., Brady L.S., Draisci G., Dubner R. Enhancement of dynorphin gene expression in spinal cord following experimental inflammation: stimulus specificity, behavioral parameters and opioid receptor binding. Pain. 35:1988;313-326.
24. Iwata K., Kanda K., Tsuboi Y., Kitajima K., Sumino R. Fos induction in the medullary dorsal horn and C1 segment of the spinal cord by acute inflammation in aged rats. Brain Res. 678:1995;127-139.
25. Iwata K., Fukuoka T., Kondo E., Tsuboi Y., Tashiro A., Noguchi K., Masuda Y., Morimoto T., Kanda K. Plastic changes in nociceptive transmission of the rat spinal cord with advancing age. J. Neurophysiol. 87:2002;1086-1093.
26. Kim Y.I., Na H.S., Yoon Y.W., Nahm S.H., Ko K.H., Hong S.K. Mechanical allodynia is more strongly manifested in older rats in an experimental model of peripheral neuropathy. Neurosci. Lett. 199:1995;158-160.
27. Knisely J.S., Hamm R.J. Physostigmine-induced analgesia in young, middle-aged, and senescent rats. Exp. Aging Res. 15:1989;3-11.
28. Knox R.J., Dickenson A.H. Effects of selective and non-selective kappa-opioid receptor agonists on cutaneous c-fiber-evoked response of rat dorsal horn neurons. Brain Res. 415:1987;21-29.
29. Ko M.L., King M.A., Gordon T.L., Crisp T. The effects of aging on spinal neurochemistry in the rat. Brain Res. Bull. 42:1997;95-98.
30. Kramer E., Bodnar R.J. Age-related decrements in morphine analgesia: a parametric analysis. Neurobiol. Aging. 7:1986;185-191.
31. MacArthur L., Ren K., Pfaffenroth E., Ruda M.A. Descending modulation of opioid-containing nociceptive neurons in rats with peripheral inflammation and hyperalgesia. Neuroscience. 88:1998;499-506.
32. Millan M.J. Descending control of pain. Prog. Neurobiol. 66:2002;355-474.
33. Morgan D.G., May P.C., Finch C.E. Dopamine and serotonin systems in human and rodent brain: effects of age and neurodegerative disease. J. Am. Geriatr. Soc. 35:1987;334-345.
34. Nahin R.L., Hylden J.L., Humphrey E. Demonstration of dynorphin A 1-8 immunoreactive axons contacting spinal cord projection neurons in a rat model of peripheral inflammation and hyperalgesia. Pain. 51:1992;135-143.
35. Nicak A. Changes of sensitivity to pain in relation to postnatal development in rats. Exp. Gerontol. 6:1971;111-114.
36. Novak J.C., Lovell J.A., Stuesse S.L., Cruce W.L., McBurney D.L., Crisp T. Aging and neuropathic pain. Brain Res. 833:1999;308-310.
37. Onaivi E.S., Payne S., Brock J.W., Hamdi A., Faroouqui S., Prasad C. Chronic nicotine reverses age-associated increases in tail-flick latency and anxiety in rats. Life Sci. 54:1994;193-202.
38. Pare W.P. Age, sex and strain differences in the aversive threshold to grid shock in the rat. J. Comp. Physiol. Psychol. 69:1969;214-218.
39. Rattan S.I. Sythesis, modifications, and turnover of proteins during aging. Exp. Gerontol. 31:1996;33-47.
40. Rigby P.W., Dieckmann M., Rhodes C., Berg P. Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I. J. Mol. Biol. 113:1977;237-251.
41. Rogue P.J., Ritz M.F., Malviya A.N. Impaired gene transcription and nuclear protein kinase C activation in the brain and liver of aged rats. FEBS Lett. 334:1993;351-354.
42. Roychoudhury R., Wu R. Terminal transferase-catalyzed addition of nucleotides to the 3′ termini of DNA. Methods Enzymol. 65:1980;43-62.
43. Ruda M.A., Iadarola M.J., Cohen L.V., Young W.S. III In situ hybridization histochemistry and immunocytochemistry reveal an increase in spinal dynorphin biosynthesis in a rat model of peripheral inflammation and hyperalgesia. Proc. Natl. Acad. Sci. U. S. A. 85:1988;622-626.
44. Stanfa L., Dickenson A. Spinal opioid systems in inflammation. Inflamm. Res. 44:1995;231-241.
45. Stuesse S.L., Crisp T., McBurney D.L., Schechter J.B., Lovell J.A., Cruse W.L.R. Neuropathic pain in aged rats: behavioral responses and astrocytic activation. Exp. Brain Res. 137:2001;219-227.
46. Wang Z., Gardell L.R., Ossipov M.H., Vanderah T.W., Brennan M.B., Hochgeschwender U., Hruby V.J., Malan T.P. Jr., Lai J., Porreca F. Pronociceptive actions of dynorphin maintain chronic neuropathic pain. J. Neurosci. 21:2001;1779-1786.