Interaction of antioxidant flavonoids with calf thymus DNA analyzed by spectroscopic and electrochemical methods

Journal of Pharmaceutical and Biomedical Analysis

Volumn 63, Issue , 2012, Pages 40-46

  Hegde, Ashwini H ^a   Prashanth, S N ^a   Seetharamappa, J ^a  

^a KARNATAK UNIVERSITY   (India)

Author keywords

DNA double helix; Flavonoid; Intercalation; Spectroscopic methods

Indexed keywords

DNA; ETHIDIUM BROMIDE; HESPERETIN; METAL ION; NARINGENIN;

ANISOTROPY; ARTICLE; CALF (BOVINE); CHEMICAL STRUCTURE; CIRCULAR DICHROISM; DIFFERENTIAL PULSE VOLTAMMETRY; DNA DENATURATION; DNA DETERMINATION; DRUG DNA BINDING; DRUG DNA INTERACTION; ELECTROCHEMISTRY; EMISSION ANISOTROPY; FLUORESCENCE; LIGHT ABSORPTION; MELTING POINT; MOLECULAR INTERACTION; PRIORITY JOURNAL; SPECTROSCOPY; THERMODYNAMICS; THYMUS;

ANTIOXIDANTS; CIRCULAR DICHROISM; DNA; ELECTROCHEMICAL TECHNIQUES; ETHIDIUM; FLAVANONES; FLUORESCENCE POLARIZATION; INTERCALATING AGENTS; MOLECULAR STRUCTURE; NUCLEIC ACID CONFORMATION; SPECTROMETRY, FLUORESCENCE; SPECTROPHOTOMETRY, ULTRAVIOLET; SPECTRUM ANALYSIS; THERMODYNAMICS; TRANSITION TEMPERATURE;

EID: 84858074537     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.01.034     Document Type: Article

References (25)

1. Fiebig T., Wan C., Kelley S.O., Barton J.K., Zewail A.H. Femtosecond dynamics of the DNA intercalator ethidium and electron transfer with mononucleotides in water. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:1187-1192.
2. Qu X., Wan C., Becker H.C., Zhong D., Zewail A.H. The anticancer drug-DNA complex: femtosecond primary dynamics for anthracycline antibiotics function. Proc. Natl. Acad. Sci. U.S.A. 2001, 98:14212-14217.
3. Neidle S., Nunn C.M. Crystal structures of nucleic acids and their drug complexes. Nat. Prod. Rep. 1998, 5:1-15.
4. Ziegler R. Vegetables, fruits and carotenoids and the risk of cancer. Am. J. Clin. Nutr. 1991, 53:251S-259S.
5. Seetharamappa J., Noboru M., Mamatha G.P., James N.H. Top Heterocycl. Chem. Chapter:Bioactive Mechanism of Interaction between Anthocyanins and Macromolecules like DNA and proteins 2008, Springer-Verlag, Berlin, Heidelburg, pp. 49-65.
6. Solimani W.R. Quercetin and DNA in solution: analysis of the dynamics of their interaction with a linear dichroism study. Int. J. Biol. Macromol. 1996, 18:287-295.
7. Sun Y., Bi S., Song D., Qiao C., Mu D., Zhang H. Study on the interaction mechanism between DNA and the main active components in Scutellaria baicalensis Georgi. Sens. Actuators B 2008, 129:799-810.
8. Bi S., Qiao C., Song D., Tian Y., Gao D., Sun Y., Zhang H. Study of interactions of flavonoids with DNA using acridine orange as a fluorescence probe. Sens. Actuators B 2006, 119:199-208.
9. Waring M.J. Complex formation between ethidium bromide and nucleic acids. J. Mol. Biol. 1965, 13:269-282.
10. Le Pecq J.B., Paoletti C. A fluorescent complex between ethidium bromide and nucleic acids: physical-chemical characterization. J. Mol. Biol. 1967, 27:87-106.
11. Chen Z.Y., Liu J., Luo D. Biochemistry Experiments 1994, Chinese University of Science and Technology Press, Hefei, p. 111.
12. Charak S., Jangir D.K., Tyagi G., Mehrotra R. Interaction studies of Epirubicin with DNA using spectroscopic techniques. J. Mol. Struct. 2011, 1000:150-154.
13. Olmsted J., Kearns D.R. Mechanism of ethidium bromide fluorescence enhancement on binding to nucleic acids. Biochemistry 1977, 16:3647-3654.
14. Baguley B.C., LeBret M. Quenching of DNA-ethidium fluorescence by amsacrine and other antitumor agents: a possible electron-transfer effect. Biochemistry 1984, 23:937-943.
15. Lakowicz J.R., Weber G. Quenching of fluorescence by oxygen. A probe for structural fluctuations in macromolecules. Biochemistry 1973, 12:4161-4170.
16. Zhang G., Fu P., Wang L., Hu M. Molecular spectroscopic studies of farrerol interaction with calf thymus DNA. J. Agric. Food Chem. 2011, 59:8944-8952.
17. Kashanian S., Askari S., Ahmadi F., Omidfar K., Ghobadi S., Tarighat F.A. In vitro study of DNA interaction with clodinafop-propargyl herbicide. DNA Cell Biol. 2008, 27:581-586.
18. Patel D.J. Nuclear magnetic resonance studies of drug-nucleic acid interactions at the synthetic DNA level in solution. Acc. Chem. Res. 1979, 12:118-125.
19. Kumar C.V., Turner R.S., Asuncion E.H. Groove binding of a styrylcyanine dye to the DNA double helix: the salt effect. J. Photochem. Photobiol. A: Chem. 1993, 74:231-238.
20. Kumar C.K., Asuncion E.H. DNA binding studies and site selective fluorescence sensitization of an anthryl probe. J. Am. Ceram. Soc. 1993, 115:8547-8553.
21. Fasman G.D. Circular Dichroism and Conformational Analysis of Biomolecules 1996, Plenum Press, New York, p. 413.
22. Rich A., Nordheim A., Wang A.H.J. The chemistry and biology of left-handed Z-DNA. Annu. Rev. Biochem. 1984, 53:791-843.
23. Yang Y.Y., Zhang Z.C., Sheng H., Liu F.Y., Qian X.H., Xu Q., Zhang Studies on the binding geometry of intercalation of 4-(2-diethylamino-ethylamino)-8-oxo- 8H-acenaphtho [1,2-b] pyrrole-9-carbonitrile to DNA by molecular spectra. Chem. J. Chin. Univ. 2007, 28:453-457.
24. Wang Y., Ni Y., Kokot S. Voltammetric behaviour of complexation of salbutamol with calf thymus DNA and its analytical application. Anal. Biochem. 2011, 419:76-80.
25. Carter M.T., Rodriguez M., Bard A.J. Voltammetric studies of the interaction of metal chelates with DNA. 2. Tris-chelated complexes of cobalt (III) and iron (II) with 1,10-phenanthroline and 2,2'-bipyridine. J. Am. Chem. Soc. 1989, 111:8901-8911.