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Volumn 32, Issue 4, 2012, Pages 221-233

Non-steroidal anti-inflammatory drugs and gastroprotection with proton pump inhibitors: A focus on ketoprofen/omeprazole

Author keywords

Fixed combinations; Gastrointestinal ulcer; Ketoprofen; Ketoprofen omeprazole; Nonsteroidal anti inflammatories; Omeprazole; Proton pump inhibitors

Indexed keywords

ACECLOFENAC; AXORID; DICLOFENAC; ESOMEPRAZOLE PLUS NAPROXEN; FLURBIPROFEN; IBUPROFEN; INDOMETACIN; KETOPROFEN; KETOPROFEN PLUS OMEPRAZOLE; KETOPROFEN PLUS SUCRALFATE; MISOPROSTOL; MISOPROSTOL PLUS NAPROXEN; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; OMEPRAZOLE; PHENYLBUTAZONE; PIROXICAM; PIRPROFEN; RANITIDINE; SULINDAC; UNCLASSIFIED DRUG;

EID: 84858066393     PISSN: 11732563     EISSN: 11791918     Source Type: Journal    
DOI: 10.2165/11596670-000000000-00000     Document Type: Review
Times cited : (37)

References (110)
  • 1
    • 0034157957 scopus 로고    scopus 로고
    • Gastrointestinal complications of prescription and over-the-counter nonsteroidal anti-inflammatory drugs: A view from the ARAMIS database. Arthritis, Rheumatism, and Aging Medical Information System
    • Mar
    • Singh G. Gastrointestinal complications of prescription and over-the-counter nonsteroidal anti-inflammatory drugs: a view from the ARAMIS database. Arthritis, Rheumatism, and Aging Medical Information System. Am J Ther 2000 Mar; 7 (2): 115-21
    • (2000) Am J Ther , vol.7 , Issue.2 , pp. 115-121
    • Singh, G.1
  • 2
    • 32244441631 scopus 로고    scopus 로고
    • NSAID-associated adverse effects and acid control aids to prevent them: A review of current treatment options
    • DOI 10.2165/00002018-200629020-00002
    • Naesdal J, Brown K. NSAID-associated adverse effects and acid control aids to prevent them: a review of current treatment options. Drug Saf 2006; 29 (2): 119-32 (Pubitemid 43213886)
    • (2006) Drug Safety , vol.29 , Issue.2 , pp. 119-132
    • Naesdal, J.1    Brown, K.2
  • 3
    • 10844268967 scopus 로고    scopus 로고
    • Current approaches to prevent NSAID-induced gastropathy - COX selectivity and beyond
    • DOI 10.1111/j.1365-2125.2004.02198.x
    • Becker JC, Domschke W, Pohle T. Current approaches to prevent NSAID-induced gastropathy: COX selectivity and beyond. Br J Clin Pharmacol 2004 Dec; 58 (6): 587-600 (Pubitemid 39665146)
    • (2004) British Journal of Clinical Pharmacology , vol.58 , Issue.6 , pp. 587-600
    • Becker, J.C.1    Domschke, W.2    Pohle, T.3
  • 4
    • 0032066149 scopus 로고    scopus 로고
    • NSAID induced gastrointestinal complications: The ARAMIS perspective - 1997
    • Singh G, Rosen Ramey D. NSAID induced gastrointestinal complications: the ARAMIS perspective - 1997. Arthritis, Rheumatism, and Aging Medical Information System. J Rheumatol Suppl. 1998 May; 51: 8-16 (Pubitemid 28210537)
    • (1998) Journal of Rheumatology , vol.25 , Issue.SUPPL. 51 , pp. 8-16
    • Singh, G.1    Ramey, D.R.2
  • 5
    • 0036678344 scopus 로고    scopus 로고
    • Do NSAIDs cause dyspepsia? A meta-analysis evaluating alternative dyspepsia definitions
    • Aug
    • Straus WL, Ofman JJ, MacLean C, et al. Do NSAIDs cause dyspepsia? A meta-analysis evaluating alternative dyspepsia definitions. Am J Gastroenterol 2002 Aug; 97 (8): 1951-8
    • (2002) Am J Gastroenterol , vol.97 , Issue.8 , pp. 1951-1958
    • Straus, W.L.1    Ofman, J.J.2    MacLean, C.3
  • 10
    • 26844442288 scopus 로고    scopus 로고
    • National adherence to evidence-based guidelines for the prescription of nonsteroidal anti-inflammatory drugs
    • DOI 10.1053/j.gastro.2005.08.003, PII S0016508505015787
    • Abraham NS, El-Serag HB, Johnson ML, et al. National adherence to evidence-based guidelines for the prescription of nonsteroidal anti-inflammatory drugs. Gastroenterology 2005 Oct; 129 (4): 1171-8 (Pubitemid 41446857)
    • (2005) Gastroenterology , vol.129 , Issue.4 , pp. 1171-1178
    • Abraham, N.S.1    El-Serag, H.B.2    Johnson, M.L.3    Hartman, C.4    Richardson, P.5    Ray, W.A.6    Smalley, W.7
  • 11
    • 33750496377 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drugs (NSAIDs), cyxlooxygenase-2 selective inhibitors (coxibs) and gastrointestinal harm: Review of clinical trials and clinical practice
    • Moore RA, Derry S, Phillips CJ, et al. Nonsteroidal antiinflammatory drugs (NSAIDs), cyxlooxygenase-2 selective inhibitors (coxibs) and gastrointestinal harm: review of clinical trials and clinical practice. BMC Musculoskelet Disord 2006; 7: 79
    • (2006) BMC Musculoskelet Disord , vol.7 , pp. 79
    • Moore, R.A.1    Derry, S.2    Phillips, C.J.3
  • 12
    • 43049175244 scopus 로고    scopus 로고
    • Co-prescribing of proton pump inhibitors among chronic users of NSAIDs in the UK
    • (Oxford) Apr
    • Suh DC, Hunsche E, Shin HC, et al. Co-prescribing of proton pump inhibitors among chronic users of NSAIDs in the UK. Rheumatology (Oxford) 2008 Apr; 47 (4): 458-63
    • (2008) Rheumatology , vol.47 , Issue.4 , pp. 458-463
    • Suh, D.C.1    Hunsche, E.2    Shin, H.C.3
  • 13
    • 33750796675 scopus 로고    scopus 로고
    • Impact of adherence to concomitant gastroprotective therapy on nonsteroidal-related gastroduodenal ulcer complications
    • Nov
    • Goldstein JL, Howard KB, Walton SM, et al. Impact of adherence to concomitant gastroprotective therapy on nonsteroidal-related gastroduodenal ulcer complications. Clin Gastroenterol Hepatol 2006 Nov; 4 (11): 1337-45
    • (2006) Clin Gastroenterol Hepatol , vol.4 , Issue.11 , pp. 1337-1345
    • Goldstein, J.L.1    Howard, K.B.2    Walton, S.M.3
  • 15
    • 39049165653 scopus 로고    scopus 로고
    • Effectiveness of national provider prescription of PPI gastroprotection among elderly NSAID users
    • DOI 10.1111/j.1572-0241.2007.01595.x
    • Abraham NS, Hartman C, Castillo D, et al. Effectiveness of national provider prescription of PPI gastroprotection among elderly NSAID users. Am J Gastroenterol 2008 Feb; 103 (2): 323-32 (Pubitemid 351248716)
    • (2008) American Journal of Gastroenterology , vol.103 , Issue.2 , pp. 323-332
    • Abraham, N.S.1    Hartman, C.2    Castillo, D.3    Richardson, P.4    Smalley, W.5
  • 16
    • 0025998097 scopus 로고
    • Risk for serious gastrointestinal complications related to use of nonsteroidal anti-inflammatory drugs: A meta-analysis
    • Nov 15
    • Gabriel SE, Jaakkimainen L, Bombardier C. Risk for serious gastrointestinal complications related to use of nonsteroidal anti-inflammatory drugs: a meta-analysis. Ann Intern Med 1991 Nov 15; 115 (10): 787-96
    • (1991) Ann Intern Med , vol.115 , Issue.10 , pp. 787-796
    • Gabriel, S.E.1    Jaakkimainen, L.2    Bombardier, C.3
  • 17
    • 0029162250 scopus 로고
    • Misoprostol reduces serious gastrointestinal complications in patients with rheumatoid arthritis receiving nonsteroidal antiinflammatory drugs: A randomized, double-blind, placebocontrolled trial
    • Aug 15
    • Silverstein FE, Graham DY, Senior JR, et al. Misoprostol reduces serious gastrointestinal complications in patients with rheumatoid arthritis receiving nonsteroidal antiinflammatory drugs: a randomized, double-blind, placebocontrolled trial. Ann Intern Med 1995 Aug 15; 123 (4): 241-9
    • (1995) Ann Intern Med , vol.123 , Issue.4 , pp. 241-249
    • Silverstein, F.E.1    Graham, D.Y.2    Senior, J.R.3
  • 18
    • 0028327671 scopus 로고
    • Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs
    • DOI 10.1016/S0140-6736(94)91843-0
    • Garcia Rodriguez LA, Jick H. Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs. Lancet 1994 Mar 26; 343 (8900): 769-72 (Pubitemid 24098698)
    • (1994) Lancet , vol.343 , Issue.8900 , pp. 769-772
    • Garcia, R.L.A.1    Jick, H.2
  • 19
    • 33847283058 scopus 로고    scopus 로고
    • Inappropriate prevention of NSAID-induced gastrointestinal events among long-term users in the elderly
    • DOI 10.2165/00002512-200724020-00004
    • Lanas A, Ferrandez A. Inappropriate prevention of NSAID-induced gastrointestinal events among long-term users in the elderly. Drugs Aging 2007; 24 (2): 121-31 (Pubitemid 46327571)
    • (2007) Drugs and Aging , vol.24 , Issue.2 , pp. 121-131
    • Lanas, A.1    Ferrandez, A.2
  • 20
    • 0036378168 scopus 로고    scopus 로고
    • Dose-response relationships between individual nonaspirin nonsteroidal anti-inflammatory drugs (NANSAIDs) and serious upper gastrointestinal bleeding: A meta-analysis based on individual patient data
    • Sep
    • Lewis SC, Langman MJ, Laporte JR, et al. Dose-response relationships between individual nonaspirin nonsteroidal anti-inflammatory drugs (NANSAIDs) and serious upper gastrointestinal bleeding: a meta-analysis based on individual patient data. Br J Clin Pharmacol 2002 Sep; 54 (3): 320-6
    • (2002) Br J Clin Pharmacol , vol.54 , Issue.3 , pp. 320-326
    • Lewis, S.C.1    Langman, M.J.2    Laporte, J.R.3
  • 21
    • 0034707105 scopus 로고    scopus 로고
    • Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis
    • VIGOR Study Group. Nov 23
    • Bombardier C, Laine L, Reicin A, et al. Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group. N Engl J Med 2000 Nov 23; 343 (21): 1520-8
    • (2000) N Engl J Med , vol.343 , Issue.21 , pp. 1520-1528
    • Bombardier, C.1    Laine, L.2    Reicin, A.3
  • 22
    • 0034644396 scopus 로고    scopus 로고
    • Gastrointestinal toxicity with celecoxib vs nonsteroidal antiinflammatory drugs for osteoarthritis and rheumatoid arthritis: The CLASS study. A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study
    • Sep 13
    • Silverstein FE, Faich G, Goldstein JL, et al. Gastrointestinal toxicity with celecoxib vs nonsteroidal antiinflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study. A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study. JAMA 2000 Sep 13; 284 (10): 1247-55
    • (2000) JAMA , vol.284 , Issue.10 , pp. 1247-1255
    • Silverstein, F.E.1    Faich, G.2    Goldstein, J.L.3
  • 23
    • 0028353941 scopus 로고
    • Risks of bleeding peptic ulcer associated with individual non-steroidal anti-inflammatory drugs
    • Apr 30
    • Langman MJ, Weil J, Wainwright P, et al. Risks of bleeding peptic ulcer associated with individual non-steroidal anti-inflammatory drugs. Lancet 1994 Apr 30; 343 (8905): 1075-8
    • (1994) Lancet , vol.343 , Issue.8905 , pp. 1075-1078
    • Langman, M.J.1    Weil, J.2    Wainwright, P.3
  • 24
    • 0033026393 scopus 로고    scopus 로고
    • Prophylaxis and treatment of NSAID-induced gastroduodenal disorders
    • DOI 10.2165/00002018-199920060-00006
    • La Corte R, Caselli M, Castellino G, et al. Prophylaxis and treatment of NSAID-induced gastroduodenal disorders. Drug Saf 1999 Jun; 20 (6): 527-43 (Pubitemid 29296598)
    • (1999) Drug Safety , vol.20 , Issue.6 , pp. 527-543
    • La, C.R.1    Caselli, M.2    Castellino, G.3    Bajocchi, G.4    Trotta, F.5
  • 25
    • 0025852139 scopus 로고
    • Corticosteroid use and peptic ulcer disease: Role of nonsteroidal anti-inflammatory drugs
    • May 1
    • Piper JM,RayWA, Daugherty JR, et al.Corticosteroid use and peptic ulcer disease: role of nonsteroidal anti-inflammatory drugs. Ann InternMed 1991 May 1; 114 (9): 735-40
    • (1991) Ann InternMed , vol.114 , Issue.9 , pp. 735-740
    • Piper, J.M.1    Ray, W.A.2    Daugherty, J.R.3
  • 26
    • 33749680192 scopus 로고    scopus 로고
    • Gastroprotective strategies among NSAID users: Guidelines for appropriate use in chronic illness
    • Targownik LE, Thomson PA. Gastroprotective strategies among NSAID users: guidelines for appropriate use in chronic illness. Can Fam Physician 2006 Sep; 52 (9): 1100-5 (Pubitemid 44553332)
    • (2006) Canadian Family Physician , vol.52 , Issue.9 SEPT. , pp. 1100-1105
    • Targownik, L.E.1    Thomson, P.A.2
  • 27
    • 74449093320 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drugs: Adverse effects and their prevention
    • Feb
    • Vonkeman HE, van de Laar MA. Nonsteroidal antiinflammatory drugs: adverse effects and their prevention. Semin Arthritis Rheum 2010 Feb; 39 (4): 294-312
    • (2010) Semin Arthritis Rheum , vol.39 , Issue.4 , pp. 294-312
    • Vonkeman, H.E.1    Van De Laar, M.A.2
  • 28
    • 0026079757 scopus 로고
    • Low-dose antacids and nonsteroidal anti-inflammatory drug-induced gastropathy in humans
    • Sievert W, Stern AI, Lambert JR, et al. Low-dose antacids and nonsteroidal anti-inflammatory drug-induced gastropathy in humans. J Clin Gastroenterol 1991; 13 (Suppl. 1): S145-8
    • (1991) J Clin Gastroenterol , vol.13 , Issue.SUPPL. 1
    • Sievert, W.1    Stern, A.I.2    Lambert, J.R.3
  • 29
    • 0030015717 scopus 로고    scopus 로고
    • Gastrointestinal tract complications of nonsteroidal anti-inflammatory drug treatment in rheumatoid arthritis: A prospective observational cohort study
    • Jul 22
    • Singh G, Ramey DR, Morfeld D, et al. Gastrointestinal tract complications of nonsteroidal anti-inflammatory drug treatment in rheumatoid arthritis: a prospective observational cohort study. Arch Intern Med 1996 Jul 22; 156 (14): 1530-6
    • (1996) Arch Intern Med , vol.156 , Issue.14 , pp. 1530-1536
    • Singh, G.1    Ramey, D.R.2    Morfeld, D.3
  • 30
    • 0025737891 scopus 로고
    • Misoprostol compared with sucralfate in the prevention of nonsteroidal anti-inflammatory drug-induced gastric ulcer: A randomized, controlled trial
    • Aug 1
    • Agrawal NM, Roth S, Graham DY, et al. Misoprostol compared with sucralfate in the prevention of nonsteroidal anti-inflammatory drug-induced gastric ulcer: a randomized, controlled trial. Ann Intern Med 1991 Aug 1; 115 (3): 195-200
    • (1991) Ann Intern Med , vol.115 , Issue.3 , pp. 195-200
    • Agrawal, N.M.1    Roth, S.2    Graham, D.Y.3
  • 31
    • 0022483175 scopus 로고
    • Protective effect of enprostil against aspirin-induced gastroduodenal mucosal injury in man. Comparison with cimetidine and sucralfate
    • Stiel D, Ellard KT, Hills LJ, et al. Protective effect of enprostil against aspirin-induced gastroduodenal mucosal injury in man: comparison with cimetidine and sucralfate. Am J Med 1986 Aug 18; 81 (2A): 54-8 (Pubitemid 16013731)
    • (1986) American Journal of Medicine , vol.81 , Issue.2 A , pp. 54-58
    • Stiel, D.1    Ellard, K.T.2    Hills, L.J.3    Brooks, P.M.4
  • 32
    • 0028077024 scopus 로고
    • Ranitidine in the prevention of non-steroidal anti-inflammatory drug-associated gastric and duodenal ulceration in arthritic patients
    • French PC, Darekar BS,Mills JG, et al. Ranitidine in the prevention of non-steroidal anti-inflammatory drug-associated gastric and duodenal ulceration in arthritic patients. European J Gastroenterol Hepatol 1994; 6 (12): 1141-7 (Pubitemid 24351877)
    • (1994) European Journal of Gastroenterology and Hepatology , vol.6 , Issue.12 , pp. 1141-1147
    • French, P.C.1    Darekar, B.S.2    Mills, J.G.3    Wood, J.S.4
  • 33
    • 0023706934 scopus 로고
    • Prevention of gastroduodenal damage induced by non-steroidal antiinflammatory drugs: Controlled trial of ranitidine
    • Oct 22
    • Ehsanullah RS, Page MC, Tildesley G, et al. Prevention of gastroduodenal damage induced by non-steroidal antiinflammatory drugs: controlled trial of ranitidine. BMJ 1988 Oct 22; 297 (6655): 1017-21
    • (1988) BMJ , vol.297 , Issue.6655 , pp. 1017-1021
    • Ehsanullah, R.S.1    Page, M.C.2    Tildesley, G.3
  • 34
    • 0025911047 scopus 로고
    • Ranitidine prevents duodenal ulcers associated with non-steroidal antiinflammatory drug therapy
    • Apr
    • Robinson M, Mills RJ, Euler AR. Ranitidine prevents duodenal ulcers associated with non-steroidal antiinflammatory drug therapy. Aliment Pharmacol Ther 1991 Apr; 5 (2): 143-50
    • (1991) Aliment Pharmacol Ther , vol.5 , Issue.2 , pp. 143-150
    • Robinson, M.1    Mills, R.J.2    Euler, A.R.3
  • 37
    • 0023697639 scopus 로고
    • Prevention of NSAID-induced gastric ulcer with misoprostol: Multicentre, double-blind, placebo-controlled trial
    • Dec 3
    • Graham DY, Agrawal NM, Roth SH. Prevention of NSAID-induced gastric ulcer with misoprostol: multicentre, double-blind, placebo-controlled trial. Lancet 1988 Dec 3; 2 (8623): 1277-80
    • (1988) Lancet , vol.2 , Issue.8623 , pp. 1277-1280
    • Graham, D.Y.1    Agrawal, N.M.2    Roth, S.H.3
  • 40
    • 0031944317 scopus 로고    scopus 로고
    • Prevention of gastroduodenal damage with omeprazole in patients receiving continuous NSAIDs treatment: A double blind placebo controlled study
    • Feb
    • Bianchi Porro G, Lazzaroni M, Petrillo M, et al. Prevention of gastroduodenal damage with omeprazole in patients receiving continuous NSAIDs treatment: a double blind placebo controlled study. Ital J Gastroenterol Hepatol 1998 Feb; 30 (1): 43-7
    • (1998) Ital J Gastroenterol Hepatol , vol.30 , Issue.1 , pp. 43-47
    • Bianchi Porro, G.1    Lazzaroni, M.2    Petrillo, M.3
  • 41
    • 33645449670 scopus 로고    scopus 로고
    • Prevention of ulcers by esomeprazole in at-risk patients using nonselective NSAIDs and COX-2 inhibitors
    • Apr
    • Scheiman JM, Yeomans ND, Talley NJ, et al. Prevention of ulcers by esomeprazole in at-risk patients using nonselective NSAIDs and COX-2 inhibitors. Am J Gastroenterol 2006 Apr; 101 (4): 701-10
    • (2006) Am J Gastroenterol , vol.101 , Issue.4 , pp. 701-710
    • Scheiman, J.M.1    Yeomans, N.D.2    Talley, N.J.3
  • 44
    • 0032579893 scopus 로고    scopus 로고
    • Progress in prophylaxis against nonsteroidal anti-inflammatory drug-associated ulcers and erosions
    • Omeprazole NSAID Steering Committee. Mar 30; discussion 9S-80S
    • Hawkey CJ. Progress in prophylaxis against nonsteroidal anti-inflammatory drug-associated ulcers and erosions. Omeprazole NSAID Steering Committee. AmJ Med 1998 Mar 30; 104 (3A): 67S-74S; discussion 9S-80S
    • (1998) AmJ Med , vol.104 , Issue.3 A
    • Hawkey, C.J.1
  • 45
    • 46449100969 scopus 로고    scopus 로고
    • Primary prevention of adverse gastroduodenal effects from short-term use of non-steroidal anti-inflammatory drugs by omeprazole 20 mg in healthy subjects: A randomized, double-blind, placebo-controlled study
    • Aug
    • Desai JC, Sanyal SM, Goo T, et al. Primary prevention of adverse gastroduodenal effects from short-term use of non-steroidal anti-inflammatory drugs by omeprazole 20 mg in healthy subjects: a randomized, double-blind, placebo-controlled study. Dig Dis Sci 2008 Aug; 53 (8): 2059-65
    • (2008) Dig Dis Sci , vol.53 , Issue.8 , pp. 2059-2065
    • Desai, J.C.1    Sanyal, S.M.2    Goo, T.3
  • 46
    • 4244046924 scopus 로고    scopus 로고
    • Pantoprazole vs placebo in prevention of NSAID-induced ulcers
    • abstract
    • Bianchi Porro G, Imbesi V, Lazzaroni M. Pantoprazole vs placebo in prevention of NSAID-induced ulcers [abstract]. Gastroenterology 1998; 114: A74
    • (1998) Gastroenterology , vol.114
    • Bianchi Porro, G.1    Imbesi, V.2    Lazzaroni, M.3
  • 47
    • 0037185429 scopus 로고    scopus 로고
    • Ulcer prevention in long-term users of nonsteroidal anti-inflammatory drugs: Results of a double-blind, randomized, multicenter, active- and placebo-controlled study of misoprostol vs lansoprazole
    • Graham DY, Agrawal NM, Campbell DR, et al. Ulcer prevention in long-term users of nonsteroidal anti-inflammatory drugs: results of a double-blind, randomized, multicenter, active- and placebo-controlled study of misoprostol vs lansoprazole. Arch Intern Med 2002 Jan 28; 162 (2): 169-75 (Pubitemid 34098186)
    • (2002) Archives of Internal Medicine , vol.162 , Issue.2 , pp. 169-175
    • Graham, D.Y.1    Agrawal, N.M.2    Campbell, D.R.3    Haber, M.M.4    Collis, C.5    Lukasik, N.L.6    Huang, B.7
  • 49
    • 34548203788 scopus 로고    scopus 로고
    • Comparison of the effects of diclofenac or other non-steroidal anti-inflammatory drugs (NSAIDs) and diclofenac or other NSAIDs in combination with proton pump inhibitors (PPI) on hospitalisation due to peptic ulcer disease
    • DOI 10.1002/pds.1387
    • Hoer A, Gothe H, Schiffhorst G, et al. Comparison of the effects of diclofenac or other non-steroidal antiinflammatory drugs (NSAIDs) and diclofenac or other NSAIDs in combination with proton pump inhibitors (PPIs) on hospitalisation due to peptic ulcer disease. Pharmacoepidemiol Drug Saf 2007 Aug; 16 (8): 854-8 (Pubitemid 47322584)
    • (2007) Pharmacoepidemiology and Drug Safety , vol.16 , Issue.8 , pp. 854-858
    • Hoer, A.1    Gothe, H.2    Schiffhorst, G.3    Sterzel, A.4    Grass, U.5    Haussler, B.6
  • 51
    • 34347398268 scopus 로고    scopus 로고
    • Proton-pump inhibitors are associated with a reduced risk for bleeding and perforated gastroduodenal ulcers attributable to non-steroidal anti-inflammatory drugs: A nested case-control study
    • Vonkeman HE, Fernandes RW, van der Palen J, et al. Proton-pump inhibitors are associated with a reduced risk for bleeding and perforated gastroduodenal ulcers attributable to non-steroidal anti-inflammatory drugs: a nested case-control study. Arthritis Res Ther 2007; 9 (3): R52
    • (2007) Arthritis Res Ther , vol.9 , Issue.3
    • Vonkeman, H.E.1    Fernandes, R.W.2    Van Der Palen, J.3
  • 55
    • 46149097354 scopus 로고    scopus 로고
    • [online]. Available from: [Accessed 2009 Jul 13]
    • National Collaborating Centre for Chronic Conditions. Osteoarthritis: national clinical guideline for care and management in adults. 2008 [online]. Available from: http:// www.nice.org.uk/nicemedia/pdf/CG059FullGuideline.pdf [Accessed 2009 Jul 13]
    • (2008) Osteoarthritis: National Clinical Guideline for Care and Management in Adults
  • 56
    • 0033710649 scopus 로고    scopus 로고
    • Recommendations for the medical management of osteoarthritis of the hip and knee: 2000 update
    • No authors listed. American College of Rheumatology Subcommittee on Osteoarthritis Guidelines Sep
    • No authors listed. Recommendations for the medical management of osteoarthritis of the hip and knee: 2000 update. American College of Rheumatology Subcommittee on Osteoarthritis Guidelines. Arthritis Rheum 2000 Sep; 43 (9): 1905-15
    • (2000) Arthritis Rheum , vol.43 , Issue.9 , pp. 1905-1915
  • 57
    • 65549119170 scopus 로고    scopus 로고
    • British Society for Rheumatology and British Health Professionals in Rheumatology guideline for the management of rheumatoid arthritis (after the first 2 years)
    • (Oxford) Apr
    • Luqmani R, Hennell S, Estrach C, et al. British Society for Rheumatology and British Health Professionals in Rheumatology guideline for the management of rheumatoid arthritis (after the first 2 years). Rheumatology (Oxford) 2009 Apr; 48 (4): 436-9
    • (2009) Rheumatology , vol.48 , Issue.4 , pp. 436-439
    • Luqmani, R.1    Hennell, S.2    Estrach, C.3
  • 58
    • 0036169930 scopus 로고    scopus 로고
    • Guidelines for the management of rheumatoid arthritis: 2002 Update
    • No authors listed. Feb
    • No authors listed. Guidelines for the management of rheumatoid arthritis: 2002 Update. Arthritis Rheum 2002 Feb; 46 (2): 328-46
    • (2002) Arthritis Rheum , vol.46 , Issue.2 , pp. 328-346
  • 60
    • 0029398922 scopus 로고
    • Diclofenac/misoprostol: A review of its pharmacology and therapeutic efficacy in painful inflammatory conditions
    • Nov
    • Davis R, Yarker YE, Goa KL. Diclofenac/misoprostol: a review of its pharmacology and therapeutic efficacy in painful inflammatory conditions. Drugs Aging 1995 Nov; 7 (5): 372-93
    • (1995) Drugs Aging , vol.7 , Issue.5 , pp. 372-393
    • Davis, R.1    Yarker, Y.E.2    Goa, K.L.3
  • 61
    • 0026486218 scopus 로고
    • Overall safety of Arthrotec
    • Geis GS. Overall safety of Arthrotec. Scand J Rheumatol Suppl. 1992; 96: 33-6
    • (1992) Scand J Rheumatol Suppl , vol.96 , pp. 33-36
    • Geis, G.S.1
  • 62
    • 0028649470 scopus 로고
    • Arthrotec, diclofenac and ibuprofen in general practice
    • Kiff PS, Stead H, Morant SV, et al. Arthrotec, diclofenac and ibuprofen in general practice. Eur J Rheumatol Inflamm 1994; 14 (3 Suppl.): 31-8
    • (1994) Eur J Rheumatol Inflamm , vol.14 , Issue.3 SUPPL. , pp. 31-38
    • Kiff, P.S.1    Stead, H.2    Morant, S.V.3
  • 63
    • 0027732735 scopus 로고
    • Double-blind comparison of efficacy and gastroduodenal safety of diclofenac/misoprostol, piroxicam, and naproxen in the treatment of osteoarthritis
    • Melo Gomes JA, Roth SH, Zeeh J, et al. Double-blind comparison of efficacy and gastroduodenal safety of diclofenac/ misoprostol, piroxicam, and naproxen in the treatment of osteoarthritis. Ann Rheum Dis 1993 Dec; 52 (12): 881-5 (Pubitemid 24019145)
    • (1993) Annals of the Rheumatic Diseases , vol.52 , Issue.12 , pp. 881-885
    • Melo, G.J.A.1    Roth, S.H.2    Zeeh, J.3    Bruyn, G.A.W.4    Woods, E.M.5    Geis, G.S.6
  • 64
    • 66149185085 scopus 로고    scopus 로고
    • Meda. [online]. Available from URL: [Accessed 2010 Nov 8]
    • Meda. Axorid: summary of product characteristics. 2010 [online]. Available from URL: http://www.medicines.org. uk/emc/medicine/22656/SPC/ Axorid+modified-release+ capsules/ [Accessed 2010 Nov 8]
    • (2010) Axorid: Summary of Product Characteristics
  • 65
    • 0024542261 scopus 로고
    • NSAIDS: Mechanisms and pathways of action
    • (Off Ed) Mar 15
    • Hochberg MC. NSAIDS: mechanisms and pathways of action. Hosp Pract (Off Ed) 1989 Mar 15; 24 (3): 185-90, 95, 98
    • (1989) Hosp Pract , vol.24 , Issue.3
    • Hochberg, M.C.1
  • 66
    • 0022453025 scopus 로고
    • Ketoprofen: A review of its pharmacologic and clinical properties
    • Kantor TG. Ketoprofen: a review of its pharmacologic and clinical properties. Pharmacotherapy 1986 May-Jun; 6 (3): 93-103 (Pubitemid 16003473)
    • (1986) Pharmacotherapy , vol.6 , Issue.3 , pp. 93-103
    • Kantor, T.G.1
  • 67
    • 0025943103 scopus 로고
    • 20 years' experience with ketoprofen
    • Veys EM. 20 years' experience with ketoprofen. Scand J Rheumatol Suppl. 1991; 90: 1-44
    • (1991) Scand J Rheumatol Suppl , vol.90 , pp. 1-44
    • Veys, E.M.1
  • 68
    • 0024226551 scopus 로고
    • The clinical pharmacology of ketoprofen
    • Dec
    • Williams RL, Upton RA. The clinical pharmacology of ketoprofen. J Clin Pharmacol 1988 Dec; 28 (12 Suppl.): S13-22
    • (1988) J Clin Pharmacol , vol.28 , Issue.12 SUPPL.
    • Williams, R.L.1    Upton, R.A.2
  • 69
    • 0022994075 scopus 로고
    • Non-steroidal antiinflammatory drug therapy: Advantages and disadvantages of long half-life drugs versus slow-release formulations
    • Folco G, Borghi C, Berti F. Non-steroidal antiinflammatory drug therapy: advantages and disadvantages of long halflife drugs versus slow-release formulations. Int J Clin Pharmacol Res 1986; 6 (6): 475-80 (Pubitemid 17213192)
    • (1986) International Journal of Clinical Pharmacology Research , vol.6 , Issue.6 , pp. 475-480
    • Folco, G.1    Borghi, C.2    Berti, F.3
  • 70
    • 0021255596 scopus 로고
    • A comparative trial of a controlled-release formulation of ketoprofen ('Oruvail') and a conventional capsule formulation of ketoprofen ('Orudis') in patients with osteoarthritis of the hip
    • Morley KD, Bernstein RM, Hughes GR, et al. A comparative trial of a controlled-release formulation of ketoprofen ('Oruvail') and a conventional capsule formulation of ketoprofen ('Orudis') in patients with osteoarthritis of the hip. Curr Med Res Opin 1984; 9 (1): 28-34 (Pubitemid 14134582)
    • (1984) Current Medical Research and Opinion , vol.9 , Issue.1 , pp. 28-34
    • Morley, K.D.1    Bernstein, R.M.2    Hughes, G.R.V.3
  • 71
    • 0027482294 scopus 로고
    • Nimesulide in the treatment of osteoarthritis: Double-blind studies in comparison with piroxicam, ketoprofen and placebo
    • Dreiser RL, Riebenfeld D. Nimesulide in the treatment of osteoarthritis: double-blind studies in comparison with piroxicam, ketoprofen and placebo.Drugs 1993; 46 Suppl. 1: 191-5 (Pubitemid 23324650)
    • (1993) Drugs , vol.46 , Issue.SUPPL.1 , pp. 191-195
    • Dreiser, R.L.1    Riebenfeld, D.2
  • 72
    • 84858038252 scopus 로고
    • A double-blind cross-over comparative study of ketoprofen versus naproxen in the treatment of osteoarthritis of the knee
    • abstract
    • Leopold M. A double-blind cross-over comparative study of ketoprofen versus naproxen in the treatment of osteoarthritis of the knee [abstract]. Scand J Gastroenterol 1980; 33: 45
    • (1980) Scand J Gastroenterol , vol.33 , pp. 45
    • Leopold, M.1
  • 73
    • 0025688655 scopus 로고
    • Comparison of the efficacy and tolerability of ketoprofen (Oruvail) 200 mg once daily with indomethacin (Indocid R) 75 mg twice daily in osteoarthritis of the knee and hip: A double-blind, within-patient, randomized trial
    • Hossain MA. Comparison of the efficacy and tolerability of ketoprofen (Oruvail) 200 mg once daily with indomethacin (Indocid R) 75 mg twice daily in osteoarthritis of the knee and hip: a double-blind, within-patient, randomized trial. Clinical Trial Journal 1990; 27: 268-77
    • (1990) Clinical Trial Journal , vol.27 , pp. 268-277
    • Hossain, M.A.1
  • 74
    • 0015515237 scopus 로고
    • Orudis in management of rheumatoid arthritis and osteoarthrosis of the hip: Comparison with indomethacin
    • Nov 18
    • Gyory AN, Bloch M, Burry HC, et al. Orudis in management of rheumatoid arthritis and osteoarthrosis of the hip: comparison with indomethacin. Br Med J 1972 Nov 18; 4 (5837): 398-400
    • (1972) Br Med J , vol.4 , Issue.5837 , pp. 398-400
    • Gyory, A.N.1    Bloch, M.2    Burry, H.C.3
  • 75
    • 0016266412 scopus 로고
    • Ketoprofen in the management of osteoarthrosis of the hip: Comparison with phenylbutazone
    • Aug
    • Bresnihan FP, Grahame R, Burry HC. Ketoprofen in the management of osteoarthrosis of the hip: comparison with phenylbutazone.RheumatolRehabil 1974Aug; 13 (3): 125-31
    • (1974) RheumatolRehabil , vol.13 , Issue.3 , pp. 125-131
    • Bresnihan, F.P.1    Grahame, R.2    Burry, H.C.3
  • 76
    • 0017096224 scopus 로고
    • Double blind cross over study of ketoprofen and phenylbutazone in patients with chronic osteoarthrosis of the hip
    • Cardoe N. Double-blind cross-over study of ketoprofen and phenylbutazone in patients with chronic osteoarthrosis of the hip. Rheumatol Rehabil 1976; Suppl: 27-33 (Pubitemid 8015443)
    • (1976) Rheumatology and Rehabilitation , vol.15 , Issue.SUPPL. , pp. 27-33
    • Cardoe, N.1
  • 77
    • 0019592924 scopus 로고
    • A comparative study of efficacy and tolerability of ketoprofen and piroxicam
    • abstract Jul-Aug
    • Lang E, Steger W. A comparative study of efficacy and tolerability of ketoprofen and piroxicam [abstract]. Br J Clin Pract 1981 Jul-Aug; 35 (7-8): 267
    • (1981) Br J Clin Pract , vol.35 , Issue.7-8 , pp. 267
    • Lang, E.1    Steger, W.2
  • 79
    • 0024206671 scopus 로고
    • Comparison of efficacy of and tolerance to ketoprofen and diclofenac sodium in the treatment of rheumatoid arthritis
    • Boey ML, Rae S, Feng PH. Comparison of efficacy of and tolerance to ketoprofen and diclofenac sodium in the treatment of rheumatoid arthritis. Singapore Med J 1988 Jun; 29 (3): 240-5 (Pubitemid 19030345)
    • (1988) Singapore Medical Journal , vol.29 , Issue.3 , pp. 240-245
    • Boey, M.L.1    Rae, S.2    Feng, P.H.3
  • 81
    • 0029086612 scopus 로고
    • Aceclofenac in comparison to ketoprofen in the treatment of rheumatoid arthritis
    • Martin-Mola E, Gijon-Banos J, Ansoleaga JJ. Aceclofenac in comparison to ketoprofen in the treatment of rheumatoid arthritis. Rheumatol Int 1995; 15 (3): 111-6
    • (1995) Rheumatol Int , vol.15 , Issue.3 , pp. 111-116
    • Martin-Mola, E.1    Gijon-Banos, J.2    Ansoleaga, J.J.3
  • 82
    • 84858053825 scopus 로고
    • Double-blind cross-over study of piroxicam (Felden) and ketoprofen (Orudis) in rheumatoid arthritis
    • Jalava S, Junnila SYT. Double-blind cross-over study of piroxicam (Felden) and ketoprofen (Orudis) in rheumatoid arthritis. Scand J Rheumatol 1986; 16: 68-9
    • (1986) Scand J Rheumatol , vol.16 , pp. 68-69
    • Jalava, S.1    Junnila, S.Y.T.2
  • 83
    • 0017188737 scopus 로고
    • A comparative trial of large doses of ketoprofen and indomethacin in the treatment of rheumatoid arthritis
    • El-Ghobarey AF, Rennie JA, Hadidi T, et al. A comparative trial of large doses of ketoprofen and indomethacin in the treatment of rheumatoid arthritis. Curr Med Res Opin 1976; 4 (6): 432-5
    • (1976) Curr Med Res Opin , vol.4 , Issue.6 , pp. 432-435
    • El-Ghobarey, A.F.1    Rennie, J.A.2    Hadidi, T.3
  • 84
    • 0017166528 scopus 로고
    • Clinical evaluation of ketoprofen (19.583 R.P.) in rheumatoid arthritis: Double-blind cross-over comparison with indomethacin
    • Fossgreen J, Kirchheiner B, Petersen FO, et al. Clinical evaluation of ketoprofen (19.583 R.P.) in rheumatoid arthritis: double-blind cross-over comparison with indomethacin. Scand J Rheumatol Suppl. 1976; 1976 (0): 93-8
    • (1976) Scand J Rheumatol Suppl , vol.1976 , Issue.0 , pp. 93-98
    • Fossgreen, J.1    Kirchheiner, B.2    Petersen, F.O.3
  • 85
    • 0027326155 scopus 로고
    • A double-blind comparison of oral ketoprofen 'controlled release' and indomethacin suppository in the treatment of rheumatoid arthritis with special regard to morning stiffness and pain on awakening
    • Uddenfeldt P, Leden I,Rubin B.A double-blind comparison of oral ketoprofen 'controlled release' and indomethacin suppository in the treatment of rheumatoid arthritis with special regard to morning stiffness and pain on awakening. Curr Med Res Opin 1993; 13 (3): 127-32 (Pubitemid 23256074)
    • (1993) Current Medical Research and Opinion , vol.13 , Issue.3 , pp. 127-132
    • Uddenfeldt, P.1    Leden, I.2    Rubin, B.3
  • 86
    • 0017092647 scopus 로고
    • A double-blind cross-over study of ketoprofen and phenylbutazone in rheumatoid arthritis
    • Peltola P. A double-blind cross-over study of ketoprofen and phenylbutazone in rheumatoid arthritis. Scand J Rheumatol 1976 Suppl.; 14: 111-3
    • (1976) Scand J Rheumatol , vol.14 , Issue.SUPPL. , pp. 111-113
    • Peltola, P.1
  • 87
    • 0027634722 scopus 로고
    • LP 200 mg flurbiprofen versus LP 200 mg ketoprofen in rheumatoid arthritis in rheumatologic practice
    • Jul-Sep
    • Vignon E, Courcier S, Laborde C, et al. LP 200 mg flurbiprofen versus LP 200 mg ketoprofen in rheumatoid arthritis in rheumatologic practice. Rev Rhum Ed Fr 1993 Jul-Sep; 60 (7-8): 530-5
    • (1993) Rev Rhum Ed Fr , vol.60 , Issue.7-8 , pp. 530-535
    • Vignon, E.1    Courcier, S.2    Laborde, C.3
  • 88
    • 0015821569 scopus 로고
    • Double-blind cross-over study of ketoprofen and ibuprofen in management of rheumatoid arthritis
    • Oct 13
    • Mills SB, Bloch M, Bruckner FE. Double-blind cross-over study of ketoprofen and ibuprofen in management of rheumatoid arthritis. Br Med J 1973 Oct 13; 4 (5884): 82-4
    • (1973) Br Med J , vol.4 , Issue.5884 , pp. 82-84
    • Mills, S.B.1    Bloch, M.2    Bruckner, F.E.3
  • 89
    • 0018759193 scopus 로고
    • A double-blind cross-over evaluation of ketoprofen (orudis) and ibuprofen in the management of rheumatoid arthritis
    • Montrone F, Fumagalli M, Pellegrini P, et al. A doubleblind cross-over evaluation of ketoprofen (Orudis) and ibuprofen in the management of rheumatoid arthritis. Rheumatol Rehabil 1979 May; 18 (2): 114-8 (Pubitemid 9194864)
    • (1979) Rheumatology and Rehabilitation , vol.18 , Issue.2 , pp. 114-118
    • Montrone, F.1    Fumagalli, M.2    Pellegrini, P.3
  • 90
    • 0017499876 scopus 로고
    • Doubleblind, multi-centre parallel trial of ketoprofen and ibuprofen in the treatment of rheumatoid arthritis
    • Calin A, Bennett RM, Sukhupunyaraksa S, et al. Doubleblind, multi-centre parallel trial of ketoprofen and ibuprofen in the treatment of rheumatoid arthritis. J Rheumatol 1977; 4 (2): 153-7
    • (1977) J Rheumatol , vol.4 , Issue.2 , pp. 153-157
    • Calin, A.1    Bennett, R.M.2    Sukhupunyaraksa, S.3
  • 91
    • 0018149315 scopus 로고
    • A comparative trial of ketoprofen and ibuprofen in patients with rheumatic disease
    • Saxena RP, Saxena U. A comparative trial of ketoprofen and ibuprofen in patients with rheumatic disease. Curr Med Res Opin 1978; 5 (6): 484-8 (Pubitemid 8365510)
    • (1978) Current Medical Research and Opinion , vol.5 , Issue.6 , pp. 484-488
    • Saxena, R.P.1    Saxena, U.2
  • 93
    • 0017096228 scopus 로고
    • Double blind study of ketoprofen and phenylbutazone in ankylosing spondylitis
    • Jessop JD. Double-blind study of ketoprofen and phenylbutazone in ankylosing spondylitis. Rheumatol Rehabil 1976 Suppl.: 37-42 (Pubitemid 8015445)
    • (1976) Rheumatology and Rehabilitation , vol.15 , Issue.SUPPL. , pp. 37-42
    • Jessop, J.D.1
  • 94
    • 0016821291 scopus 로고
    • Ketoprofen (Orudis) in ankylosing spondylitis
    • May 14
    • Treadwell BL, Tweed JM. Ketoprofen (Orudis) in ankylosing spondylitis. N ZMed J 1975May 14; 81 (539): 411-3
    • (1975) N ZMed J , vol.81 , Issue.539 , pp. 411-413
    • Treadwell, B.L.1    Tweed, J.M.2
  • 95
    • 0019954127 scopus 로고
    • SPONDYLARTHRITE ANKYLOSANTE. ESSAI COMPARATIF DE DEUX ANTI-INLFLAMMATOIRES NON STEROIDIENS, LE PIRPROFENE ET LE KETOPROFENE
    • Renier JC, Fournier M, Loyau G, et al. Ankylosing spondylitis: comparative trial of two non-steroidal antiinflammatory agents - pirprofen and ketoprofen. Nouv Presse Med 1982 Aug 28; 11 (33): 2494-6 (Pubitemid 12046867)
    • (1982) Nouvelle Presse Medicale , vol.11 , Issue.33 , pp. 2494-2496
    • Renier, J.C.1    Fournier, M.2    Loyau, G.3    Roux, H.4
  • 96
    • 0022393978 scopus 로고
    • A double-blind, crossover study of a sustained-release tablet of ketoprofen and normal ketoprofen capsules in the treatment of patients with osteoarthritis
    • Toft B, Christophersen J, Christensen N, et al.A double-blind, crossover study of a sustained-release tablet of ketoprofen and normal ketoprofen capsules in the treatment of patients with osteoarthritis. Curr Med Res Opin 1985; 9 (10): 708-12 (Pubitemid 16203077)
    • (1985) Current Medical Research and Opinion , vol.9 , Issue.10 , pp. 708-712
    • Toft, B.1    Christophersen, J.2    Christensen, N.3
  • 97
    • 0022859061 scopus 로고
    • Double-blind comparative multicenter study of the efficacy and safety of a slow-release tablet of 200-mg ketoprofen once daily and a 50-mg ketoprofen capsule four times daily
    • Teule M. Double-blind comparative multicenter study of the efficacy and safety of a slow-release tablet of 200 mg ketoprofen and a 50mg ketoprofen capsule four times daily. Curr Ther Res 1986; 40: 1129-46 (Pubitemid 17224836)
    • (1986) Current Therapeutic Research - Clinical and Experimental , vol.40 , Issue.6 , pp. 1129-1146
    • Teule, M.1
  • 99
    • 0028114297 scopus 로고
    • Ketoprofen extended-release capsules: A new formulation for the treatment of osteoarthritis and rheumatoid arthritis
    • Schumacher Jr HR. Ketoprofen extended-release capsules: a new formulation for the treatment of osteoarthritis and rheumatoid arthritis. Clin Ther 1994Mar-Apr; 16 (2): 145-59 (Pubitemid 24321651)
    • (1994) Clinical Therapeutics , vol.16 , Issue.2 , pp. 145-159
    • Schumacher Jr., H.R.1
  • 101
    • 0029977698 scopus 로고    scopus 로고
    • Pharmacokinetics, metabolism and interactions of acid pump inhibitors. Focus on omeprazole, lansoprazole and pantoprazole
    • Andersson T. Pharmacokinetics, metabolism and interactions of acid pump inhibitors: focus on omeprazole, lansoprazole and pantoprazole. Clin Pharmacokinet 1996 Jul; 31 (1): 9-28 (Pubitemid 26238200)
    • (1996) Clinical Pharmacokinetics , vol.31 , Issue.1 , pp. 9-28
    • Andersson, T.1
  • 102
    • 0032510378 scopus 로고    scopus 로고
    • Omeprazole compared with misoprostol for ulcers associated with nonsteroidal antiinflammatory drugs
    • DOI 10.1056/NEJM199803123381105
    • Hawkey CJ, Karrasch JA, Szczepanski L, et al. Omeprazole compared with misoprostol for ulcers associated with nonsteroidal antiinflammatory drugs. Omeprazole versus Misoprostol for NSAID-induced Ulcer Management (OMNIUM) study group. N Engl J Med 1998 Mar 12; 338 (11): 727-34 (Pubitemid 28115091)
    • (1998) New England Journal of Medicine , vol.338 , Issue.11 , pp. 727-734
    • Hawkey, C.J.1    Karrasch, J.A.2    Szczepanski, L.3    Walker, D.G.4    Barkun, A.5    Swannell, A.J.6    Yeomans, N.D.7
  • 103
    • 0032510315 scopus 로고    scopus 로고
    • A comparison of omeprazole with ranitidine for ulcers associated with nonsteroidal antiinflammatory drugs
    • Acid Suppression Trial: Ranitidine versusOmeprazole forNSAID- associatedUlcer Treatment (ASTRONAUT) study group. Mar 12
    • Yeomans ND, Tulassay Z, Juhasz L, et al. A comparison of omeprazole with ranitidine for ulcers associated with nonsteroidal antiinflammatory drugs. Acid Suppression Trial: Ranitidine versusOmeprazole forNSAID-associatedUlcer Treatment (ASTRONAUT) study group. N Engl J Med 1998 Mar 12; 338 (11): 719-26
    • (1998) N Engl J Med , vol.338 , Issue.11 , pp. 719-726
    • Yeomans, N.D.1    Tulassay, Z.2    Juhasz, L.3
  • 104
    • 70349667386 scopus 로고    scopus 로고
    • Evidence for endoscopic ulcers as meaningful surrogate endpoint for clinically significant upper gastrointestinal harm
    • Nov
    • Moore A, Bjarnason I, Cryer B, et al. Evidence for endoscopic ulcers as meaningful surrogate endpoint for clinically significant upper gastrointestinal harm. Clin Gastroenterol Hepatol 2009 Nov; 7 (11): 1156-63
    • (2009) Clin Gastroenterol Hepatol , vol.7 , Issue.11 , pp. 1156-1163
    • Moore, A.1    Bjarnason, I.2    Cryer, B.3
  • 106
    • 41349090797 scopus 로고    scopus 로고
    • The relative efficacies of gastroprotective strategies in chronic users of nonsteroidal anti-inflammatory drugs
    • Apr
    • Targownik LE, Metge CJ, Leung S, et al. The relative efficacies of gastroprotective strategies in chronic users of nonsteroidal anti-inflammatory drugs. Gastroenterology 2008 Apr; 134 (4): 937-44
    • (2008) Gastroenterology , vol.134 , Issue.4 , pp. 937-944
    • Targownik, L.E.1    Metge, C.J.2    Leung, S.3
  • 107
    • 0345059234 scopus 로고    scopus 로고
    • Secondary prevention of upper gastrointestinal bleeding associated with maintenance acid-suppressing treatment in patients with peptic ulcer bleed
    • Garcia Rodriguez LA, Ruigomez A. Secondary prevention of upper gastrointestinal bleeding associated with maintenance acid-suppressing treatment in patients with peptic ulcer bleed. Epidemiology 1999 May; 10 (3): 228-32 (Pubitemid 29187754)
    • (1999) Epidemiology , vol.10 , Issue.3 , pp. 228-232
    • Rodrigiiez, L.A.G.1    Ruigomez, A.2
  • 108
    • 33846822336 scopus 로고    scopus 로고
    • Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: A randomised comparison
    • DOI 10.1016/S0140-6736(07)60234-7, PII S0140673607602347
    • Laine L, Curtis SP, Cryer B, et al. Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison. Lancet 2007 Feb 10; 369 (9560): 465-73 (Pubitemid 46217814)
    • (2007) Lancet , vol.369 , Issue.9560 , pp. 465-473
    • Laine, L.1    Curtis, S.P.2    Cryer, B.3    Kaur, A.4    Cannon, C.P.5


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