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Volumn 119, Issue 10, 2012, Pages 2209-2218

How I treat heparin-induced thrombocytopenia

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; ANTICOAGULANT AGENT; ARGATROBAN; BLOOD CLOTTING FACTOR 10A INHIBITOR; CARBON 14; DANAPAROID; DESULFATOHIRUDIN; FONDAPARINUX; HEPARIN; HIRULOG; LEPIRUDIN; LOW MOLECULAR WEIGHT HEPARIN; SEROTONIN; THROMBIN INHIBITOR; THROMBOCYTE FACTOR 4;

EID: 84858057979     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-11-376293     Document Type: Review
Times cited : (125)

References (106)
  • 1
    • 0026638091 scopus 로고
    • Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin-induced thrombocytopenia
    • Amiral J, Bridey F, Dreyfus M, et al. Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin-induced thrombocytopenia. Thromb Haemost. 1992;68(1):95- 96.
    • (1992) Thromb Haemost , vol.68 , Issue.1 , pp. 95-96
    • Amiral, J.1    Bridey, F.2    Dreyfus, M.3
  • 2
    • 0001318176 scopus 로고
    • Arterial embolism occurring during systemic heparin therapy
    • Weissmann RE, Tobin RW. Arterial embolism occurring during systemic heparin therapy. AMA Arch Surg. 1958;76(2):219-227.
    • (1958) AMA Arch Surg , vol.76 , Issue.2 , pp. 219-227
    • Weissmann, R.E.1    Tobin, R.W.2
  • 3
    • 0037220153 scopus 로고    scopus 로고
    • How I treat heparin-induced thrombocytopenia and thrombosis
    • DOI 10.1182/blood-2002-04-1089
    • Alving BM. How I treat heparin-induced thrombocytopenia and thrombosis. Blood. 2003;101(1): 31-37. (Pubitemid 36025883)
    • (2003) Blood , vol.101 , Issue.1 , pp. 31-37
    • Alving, B.M.1
  • 5
    • 82555181616 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia (HIT) in 2011: An epidemic of overdiagnosis
    • Cuker A. Heparin-induced thrombocytopenia (HIT) in 2011: an epidemic of overdiagnosis. Thromb Haemost. 2011;106(6):993-994.
    • (2011) Thromb Haemost , vol.106 , Issue.6 , pp. 993-994
    • Cuker, A.1
  • 6
    • 79960644200 scopus 로고    scopus 로고
    • HIT paradigms and paradoxes
    • Warkentin TE. HIT paradigms and paradoxes. J Thromb Haemost. 2011;9(suppl 1):105-117.
    • (2011) J Thromb Haemost , vol.9 , Issue.SUPPL. 1 , pp. 105-117
    • Warkentin, T.E.1
  • 7
    • 27144527501 scopus 로고    scopus 로고
    • Risk for heparin-induced thrombocytopenia with unfractionated and low-molecular-weight heparin thromboprophylaxis: A meta-analysis
    • DOI 10.1182/blood-2005-04-1546
    • Martel N, Lee J, Wells PS. Risk for heparininduced thrombocytopenia with unfractionated and low-molecular-weight heparin thromboprophylaxis: a meta-analysis. Blood. 2005;106(8): 2710-2715. (Pubitemid 41510744)
    • (2005) Blood , vol.106 , Issue.8 , pp. 2710-2715
    • Martel, N.1    Lee, J.2    Wells, P.S.3
  • 9
    • 28444494385 scopus 로고    scopus 로고
    • Anti-platelet factor 4/heparin antibodies in orthopedic surgery patients receiving antithrombotic prophylaxis with fondaparinux or enoxaparin
    • DOI 10.1182/blood-2005-05-1938
    • Warkentin TE, Cook RJ, Marder VJ, et al. Antiplatelet factor 4/heparin antibodies in orthopedic surgery patients receiving antithrombotic prophylaxis withfondaparinux or enoxaparin. Blood. 2005;106(12): 3791-3796. (Pubitemid 41739014)
    • (2005) Blood , vol.106 , Issue.12 , pp. 3791-3796
    • Warkentin, T.E.1    Cook, R.J.2    Marder, V.J.3    Sheppard, J.-A.I.4    Moore, J.C.5    Eriksson, B.I.6    Greinacher, A.7    Kelton, J.G.8
  • 10
    • 34250856863 scopus 로고    scopus 로고
    • The incidence of recognized heparin-induced thrombocytopenia in a large, tertiary care teaching hospital
    • DOI 10.1378/chest.06-2109
    • Smythe MA, Koerber JM, Mattson JC. The incidence of recognized heparin-induced thrombocytopenia in a large, tertiary care teaching hospital. Chest. 2007;131(6):1644-1649. (Pubitemid 46981615)
    • (2007) Chest , vol.131 , Issue.6 , pp. 1644-1649
    • Smythe, M.A.1    Koerber, J.M.2    Mattson, J.C.3
  • 12
    • 0036049668 scopus 로고    scopus 로고
    • Incidence and clinical relevance of heparin-induced antibodies in patients with deep vein thrombosis treated with unfractionated or low-molecular-weight heparin
    • DOI 10.1046/j.1365-2141.2002.03687.x
    • Lindhoff-Last E, Nakov R, Misselwitz F, Breddin HK, Bauersachs R. Incidence and clinical relevance of heparin-induced antibodies in patients with deep vein thrombosis treated with unfractionated or low-molecular weight heparin. Br J Haematol. 2002;118(4): 1137-1142. (Pubitemid 35025982)
    • (2002) British Journal of Haematology , vol.118 , Issue.4 , pp. 1137-1142
    • Lindhoff-Last, E.1    Nakov, R.2    Misselwitz, F.3    Breddin, H.-K.4    Bauersachs, R.5
  • 13
    • 70349323405 scopus 로고    scopus 로고
    • Incidence of thrombocytopenia in hospitalized patients with venous thromboembolism
    • Stein PD, Hull RD, Matta F, YaekoubAY, Liang J. Incidence of thrombocytopenia in hospitalized patients with venous thromboembolism. Am J Med. 2009; 122(10):919-930.
    • (2009) Am J Med , vol.122 , Issue.10 , pp. 919-930
    • Stein, P.D.1    Hull, R.D.2    Matta, F.3    Yaekoub, A.Y.4    Liang, J.5
  • 15
    • 0034284046 scopus 로고    scopus 로고
    • Impact of the patient population on the risk for heparin-induced thrombocytopenia
    • Warkentin TE, Sheppard JA, Horsewood P, Simpson PJ, Moore JC, Kelton JG. Impact of the patient population on the risk of heparin-induced thrombocytopenia. Blood. 2000;96(5):1703-1708. (Pubitemid 30661052)
    • (2000) Blood , vol.96 , Issue.5 , pp. 1703-1708
    • Warkentin, T.E.1    Sheppard, J.-A.I.2    Horsewood, P.3    Simpson, P.J.4    Moore, J.C.5    Kelton, J.G.6
  • 16
    • 0029035681 scopus 로고
    • Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin
    • Warkentin TE, Levine MN, Hirsh J, et al. Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin. N Engl J Med. 1995;332(20):1330- 1335.
    • (1995) N Engl J Med , vol.332 , Issue.20 , pp. 1330-1335
    • Warkentin, T.E.1    Levine, M.N.2    Hirsh, J.3
  • 17
    • 77950356215 scopus 로고    scopus 로고
    • The severity of trauma determines the immune response to PF4/heparin and the frequency of heparin-induced thrombocytopenia
    • Lubenow N, Hinz P, Thomaschewski S, et al. The severity of trauma determines the immune response to PF4/heparin and the frequency of heparin- induced thrombocytopenia. Blood. 2010; 115(9):1797-1803.
    • (2010) Blood , vol.115 , Issue.9 , pp. 1797-1803
    • Lubenow, N.1    Hinz, P.2    Thomaschewski, S.3
  • 18
    • 77953286757 scopus 로고    scopus 로고
    • The 4Ts scoring system for heparin-induced thrombocytopenia in medical-surgical intensive care unit patients
    • Crowther MA, Cook DJ, Albert M, et al. The 4Ts scoring system for heparin-induced thrombocytopenia in medical-surgical intensive care unit patients. J Crit Care. 2010;25(2):287-293.
    • (2010) J Crit Care , vol.25 , Issue.2 , pp. 287-293
    • Crowther, M.A.1    Cook, D.J.2    Albert, M.3
  • 19
    • 34447556034 scopus 로고    scopus 로고
    • National survey of heparin-induced thrombocytopenia in the haemodialysis population of the UK population
    • DOI 10.1093/ndt/gfm055
    • Hutchison CA, Dasgupta I. National survey of heparin-induced thrombocytopenia in the haemodialysis population of the UK population. Nephrol Dial Transplant. 2007;22(6):1680-1684. (Pubitemid 47073768)
    • (2007) Nephrology Dialysis Transplantation , vol.22 , Issue.6 , pp. 1680-1684
    • Hutchison, C.A.1    Dasgupta, I.2
  • 21
    • 80051559509 scopus 로고    scopus 로고
    • Association of natural antiplatelet factor 4/heparin antibodies with periodontal disease
    • Greinacher A, Holtfreter B, Krauel K, et al. Association of natural antiplatelet factor 4/heparin antibodies with periodontal disease. Blood. 2011; 118(5):1395-1401.
    • (2011) Blood , vol.118 , Issue.5 , pp. 1395-1401
    • Greinacher, A.1    Holtfreter, B.2    Krauel, K.3
  • 22
    • 38349059069 scopus 로고    scopus 로고
    • Incidence and prognostic significance of thrombocytopenia in patients treated with prolonged heparin therapy
    • Oliveira GB, Crespo EM, Becker RC, et al. Incidence and prognostic significance of thrombocytopenia in patients treated with prolonged heparin therapy. Arch Intern Med. 2008;168(1):94-102.
    • (2008) Arch Intern Med , vol.168 , Issue.1 , pp. 94-102
    • Oliveira, G.B.1    Crespo, E.M.2    Becker, R.C.3
  • 23
    • 0035953702 scopus 로고    scopus 로고
    • Temporal aspects of heparin-induced thrombocytopenia
    • DOI 10.1056/NEJM200104263441704
    • Warkentin TE, Kelton JG. Temporal aspects of heparin-induced thrombocytopenia. N Engl J Med. 2001;344(17):1286-1292. (Pubitemid 32372963)
    • (2001) New England Journal of Medicine , vol.344 , Issue.17 , pp. 1286-1292
    • Warkentin, T.E.1    Kelton, J.G.2
  • 25
    • 45549099235 scopus 로고    scopus 로고
    • A Spontaneous Prothrombotic Disorder Resembling Heparin-induced Thrombocytopenia
    • DOI 10.1016/j.amjmed.2008.03.012, PII S0002934308002611
    • Warkentin TE, Makris M, Jay RM, Kelton JG. A spontaneous prothrombotic disorder resembling heparin-induced thrombocytopenia. Am J Med. 2008;121(7):632-636. (Pubitemid 351876183)
    • (2008) American Journal of Medicine , vol.121 , Issue.7 , pp. 632-636
    • Warkentin, T.E.1    Makris, M.2    Jay, R.M.3    Kelton, J.G.4
  • 26
    • 0031795614 scopus 로고    scopus 로고
    • Clinical presentation of heparin-induced thrombocytopenia
    • Warkentin TE. Clinical presentation of heparin-induced thrombocytopenia. Semin Hematol. 1998;35(4 suppl):9-16. (Pubitemid 28549557)
    • (1998) Seminars in Hematology , vol.35 , Issue.4 SUPPL. 5 , pp. 9-16
    • Warkentin, T.E.1
  • 27
    • 0037610515 scopus 로고    scopus 로고
    • An Improved Definition of Immune Heparin-Induced Thrombocytopenia in Postoperative Orthopedic Patients
    • DOI 10.1001/archinte.163.20.2518
    • Warkentin TE, Roberts RS, Hirsh J, Kelton JG. An improved definition of immune heparin-induced thrombocytopenia in postoperative orthopedic patients. Arch Intern Med. 2003;163(20):2518-2524. (Pubitemid 37385796)
    • (2003) Archives of Internal Medicine , vol.163 , Issue.20 , pp. 2518-2524
    • Warkentin, T.E.1    Roberts, R.S.2    Hirsh, J.3    Kelton, J.G.4
  • 29
    • 22144446420 scopus 로고    scopus 로고
    • Clinical features of heparin-induced thrombocytopenia including risk factors for thrombosis: A retrospective analysis of 408 patients
    • Greinacher A, Farner B, Kroll H, Kohlmann T, Warkentin TE, Eichler P. Clinical features of heparin-induced thrombocytopenia including risk factors for thrombosis: a retrospective analysis of 408 patients. Thromb Haemost. 2005;94(1):132- 135.
    • (2005) Thromb Haemost , vol.94 , Issue.1 , pp. 132-135
    • Greinacher, A.1    Farner, B.2    Kroll, H.3    Kohlmann, T.4    Warkentin, T.E.5    Eichler, P.6
  • 30
    • 0030281338 scopus 로고    scopus 로고
    • A 14-year study of heparin-induced thrombocytopenia
    • DOI 10.1016/S0002-9343(96)00258-6, PII S0002934396002586
    • Warkentin TE, Kelton JG. A 14-year study of heparin- induced thrombocytopenia. Am J Med. 1996; 101(5):502-507. (Pubitemid 126335970)
    • (1996) American Journal of Medicine , vol.101 , Issue.5 , pp. 502-507
    • Warkentin, T.E.1    Kelton, J.G.2
  • 31
    • 79953231151 scopus 로고    scopus 로고
    • Bilateral adrenal hemorrhage: The unrecognized cause of hemodynamic collapse associated with heparin-induced thrombocytopenia
    • Rosenberger LH, Smith PW, Sawyer RG, Hanks JB, Adams RB, Hedrick TL. Bilateral adrenal hemorrhage: the unrecognized cause of hemodynamic collapse associated with heparin-induced thrombocytopenia. Crit Care Med. 2011;39(4):833-838.
    • (2011) Crit Care Med , vol.39 , Issue.4 , pp. 833-838
    • Rosenberger, L.H.1    Smith, P.W.2    Sawyer, R.G.3    Hanks, J.B.4    Adams, R.B.5    Hedrick, T.L.6
  • 32
    • 0037905743 scopus 로고    scopus 로고
    • Central venous catheters and upper-extremity deep-vein thrombosis complicating immune heparin-induced thrombocytopenia
    • DOI 10.1182/blood-2002-05-1448
    • Hong AP, Cook DJ, Sigouin CS, Warkentin TE. Central venous catheters and upper-extremity deep-vein thrombosis complicating immune heparin- induced thrombocytopenia. Blood. 2003; 101(8):3049-3051. (Pubitemid 36857994)
    • (2003) Blood , vol.101 , Issue.8 , pp. 3049-3051
    • Hong, A.P.1    Cook, D.J.2    Sigouin, C.S.3    Warkentin, T.E.4
  • 33
    • 19844369268 scopus 로고    scopus 로고
    • Heparin-induced skin lesions and other unusual sequelae of the heparin-induced thrombocytopenia syndrome: A nested cohort study
    • DOI 10.1378/chest.127.5.1857
    • Warkentin TE, Roberts RS, Hirsh J, Kelton JG. Heparin-induced skin lesions and other unusual sequelae of the heparin-induced thrombocytopenia syndrome: a nested cohort study. Chest. 2005;127(5):1857-1861. (Pubitemid 46218820)
    • (2005) Chest , vol.127 , Issue.5 , pp. 1857-1861
    • Warkentin, T.E.1    Roberts, R.S.2    Hirsh, J.3    Kelton, J.G.4
  • 34
    • 77955036645 scopus 로고    scopus 로고
    • Heparin-induced non-necrotizing skin lesions: Rarely associated with heparin-induced thrombocytopenia
    • Schindewolf M, Kroll H, Ackermann H, et al. Heparin-induced non-necrotizing skin lesions: rarely associated with heparin-induced thrombocytopenia. J Thromb Haemost. 2010;8(7):1486- 1491.
    • (2010) J Thromb Haemost , vol.8 , Issue.7 , pp. 1486-1491
    • Schindewolf, M.1    Kroll, H.2    Ackermann, H.3
  • 35
    • 79551583832 scopus 로고    scopus 로고
    • The frequency and clinical significance of thrombocytopenia complicating critical illness: A systematic review
    • Hui P, Cook DJ, Lim W, Fraser GA, Arnold DM. The frequency and clinical significance of thrombocytopenia complicating critical illness: a systematic review. Chest. 2011;139(2):271-278.
    • (2011) Chest , vol.139 , Issue.2 , pp. 271-278
    • Hui, P.1    Cook, D.J.2    Lim, W.3    Fraser, G.A.4    Arnold, D.M.5
  • 36
    • 0032709832 scopus 로고    scopus 로고
    • Blood product use in cardiac revascularization: Comparison of on- and off-pump techniques
    • Nader ND, Khadra WZ, Reich NT, Bacon DR, Salerno TA, Panos AL. Blood product use in cardiac revascularization: comparison of on- and off-pump techniques. Ann Thorac Surg. 1999; 68(5):1640-1643.
    • (1999) Ann Thorac Surg , vol.68 , Issue.5 , pp. 1640-1643
    • Nader, N.D.1    Khadra, W.Z.2    Reich, N.T.3    Bacon, D.R.4    Salerno, T.A.5    Panos, A.L.6
  • 37
    • 73049094086 scopus 로고    scopus 로고
    • Early-onset and persisting thrombocytopenia in postcardiac surgery patients is rarely due to heparin-induced thrombocytopenia, even when antibody tests are positive
    • Selleng S, Malowsky B, Strobel U, et al. Early-onset and persisting thrombocytopenia in postcardiac surgery patients is rarely due to heparin-induced thrombocytopenia, even when antibody tests are positive. J Thromb Haemost. 2010;8(1): 30-36.
    • (2010) J Thromb Haemost , vol.8 , Issue.1 , pp. 30-36
    • Selleng, S.1    Malowsky, B.2    Strobel, U.3
  • 38
    • 13244282990 scopus 로고    scopus 로고
    • Diagnostic score for heparin-induced thrombocytopenia after cardiopulmonary bypass
    • Lillo-Le Louet A, Boutouyrie P, Alhenc-Gelas M, et al. Diagnostic score for heparin-induced thrombocytopenia after cardiopulmonary bypass. J Thromb Haemost. 2005;2(11):1882-1888.
    • (2005) J Thromb Haemost , vol.2 , Issue.11 , pp. 1882-1888
    • Lillo-Le Louet, A.1    Boutouyrie, P.2    Alhenc-Gelas, M.3
  • 39
    • 33644971524 scopus 로고    scopus 로고
    • Evaluation of a pretest clinical score (4 T's) for the diagnosis of heparin-induced thrombocytopenia in two clinical settings
    • Lo GK, Juhl D, Warkentin TE, Sigouin CS, Eichler P, Greinacher A. Evaluation of a pretest clinical score (4 T's) for the diagnosis of heparin-induced thrombocytopenia in two clinical settings. J Thromb Haemost. 2006;4(4):759-765.
    • (2006) J Thromb Haemost , vol.4 , Issue.4 , pp. 759-765
    • Lo, G.K.1    Juhl, D.2    Warkentin, T.E.3    Sigouin, C.S.4    Eichler, P.5    Greinacher, A.6
  • 40
    • 78650000811 scopus 로고    scopus 로고
    • The HIT Expert Probability (HEP) score: A novel pre-test probability model for heparin-induced thrombocytopenia based on broad expert opinion
    • Cuker A, Arepally G, Crowther MA, et al. The HIT Expert Probability (HEP) score: a novel pre-test probability model for heparin-induced thrombocytopenia based on broad expert opinion. J Thromb Haemost. 2010;8(12):2642-2650.
    • (2010) J Thromb Haemost , vol.8 , Issue.12 , pp. 2642-2650
    • Cuker, A.1    Arepally, G.2    Crowther, M.A.3
  • 41
    • 84858011227 scopus 로고    scopus 로고
    • Laboratory HIT testing in critically ill patients
    • abstract. Abstract 198
    • Crowther MA, Langevin S, Cooper JL, et al. Laboratory HIT testing in critically ill patients [abstract]. Am Soc Hematol Educ Program. 2011; 18(21):Abstract 198.
    • (2011) Am Soc Hematol Educ Program , vol.18 , Issue.21
    • Crowther, M.A.1    Langevin, S.2    Cooper, J.L.3
  • 42
    • 79959504577 scopus 로고    scopus 로고
    • Overdiagnosis of heparin-induced thrombocytopenia in surgical ICU patients
    • Berry C, Tcherniantchouk O, Ley EJ, et al. Overdiagnosis of heparin-induced thrombocytopenia in surgical ICU patients. J Am Coll Surg. 2011; 213(1):10-17.
    • (2011) J Am Coll Surg , vol.213 , Issue.1 , pp. 10-17
    • Berry, C.1    Tcherniantchouk, O.2    Ley, E.J.3
  • 44
    • 0032926268 scopus 로고    scopus 로고
    • Decision analysis for use of platelet aggregation test, carbon 14- serotonin release assay, and heparin-platelet factor 4 enzyme-linked immunosorbent assay for diagnosis of heparin-induced thrombocytopenia
    • Pouplard C, Amiral J, Borg JY, Laporte-Simitsidis S, Delahousse B, Gruel Y. Decision analysis for use of platelet aggregation test, carbon 14-serotonin release assay, and heparin-platelet factor 4 enzyme-linked immunosorbent assay for diagnosis of heparin- induced thrombocytopenia. Am J Clin Pathol. 1999;111(5):700-706. (Pubitemid 29200959)
    • (1999) American Journal of Clinical Pathology , vol.111 , Issue.5 , pp. 700-706
    • Pouplard, C.1    Amiral, J.2    Borg, J.-Y.3    Laporte-Simitsidis, S.4    Delahousse, B.5    Gruel, Y.6
  • 45
    • 0032958624 scopus 로고    scopus 로고
    • Antigens involved in heparin-induced thrombocytopenia
    • Amiral J. Antigens involved in heparin-induced thrombocytopenia. Semin Hematol. 1999;36(1 suppl 1):7-11. (Pubitemid 29045504)
    • (1999) Seminars in Hematology , vol.36 , Issue.SUPPL. 1 , pp. 7-11
    • Amiral, J.1
  • 46
    • 82555175361 scopus 로고    scopus 로고
    • Evaluation of a new manoparticlebased lateral flow immunoassay for the exclusion of heparin-induced thrombocytopenia
    • Sachs UJ, von Hesberg J, Santoso S, Bein G, Bakchoul T. Evaluation of a new manoparticlebased lateral flow immunoassay for the exclusion of heparin-induced thrombocytopenia. Thromb Haemost. 2011;106(6):1197-1202.
    • (2011) Thromb Haemost , vol.106 , Issue.6 , pp. 1197-1202
    • Sachs, U.J.1    Von Hesberg, J.2    Santoso, S.3    Bein, G.4    Bakchoul, T.5
  • 47
    • 79955961820 scopus 로고    scopus 로고
    • Performance of a new, rapid, automated immunoassay for the detection of antiplatelet factor 4/heparin complex antibodies
    • Davidson SJ, Ortel TL, Smith LJ. Performance of a new, rapid, automated immunoassay for the detection of antiplatelet factor 4/heparin complex antibodies. Blood Coagul Fibrinolysis. 2011; 22(4):340-344.
    • (2011) Blood Coagul Fibrinolysis , vol.22 , Issue.4 , pp. 340-344
    • Davidson, S.J.1    Ortel, T.L.2    Smith, L.J.3
  • 48
    • 36749095644 scopus 로고    scopus 로고
    • What is the potential for overdiagnosis of heparin-induced thrombocytopenia?
    • DOI 10.1002/ajh.21032
    • Lo GK, Sigouin CS, Warkentin TE. What is the potential for overdiagnosis of heparin-induced thrombocytopenia? Am J Hematol. 2007;82(12): 1037-1043. (Pubitemid 350209843)
    • (2007) American Journal of Hematology , vol.82 , Issue.12 , pp. 1037-1043
    • Lo, G.K.1    Sigouin, C.S.2    Warkentin, T.E.3
  • 49
    • 67649470557 scopus 로고    scopus 로고
    • False-positive tests for heparin-induced thrombocytopenia in patients with antiphospholipid syndrome and systemic lupus erythematosus
    • Pauzner R, Greinacher A, Selleng K, Althaus K, Shenkman B, Seligsohn U. False-positive tests for heparin-induced thrombocytopenia in patients with antiphospholipid syndrome and systemic lupus erythematosus. J Thromb Haemost. 2009; 7(7):1070-1074.
    • (2009) J Thromb Haemost , vol.7 , Issue.7 , pp. 1070-1074
    • Pauzner, R.1    Greinacher, A.2    Selleng, K.3    Althaus, K.4    Shenkman, B.5    Seligsohn, U.6
  • 50
    • 77449133188 scopus 로고    scopus 로고
    • Beta2 glycoprotein I (beta2GPI) binds platelet factor 4 (PF4): Implications for the pathogenesis of antiphospholipid syndrome
    • Sikara MP, Routsias JG, Samiotaki M, Panayotou G, Moutsopoulos HM, Vlachoyiannopoulos PG. beta2 glycoprotein I (beta2GPI) binds platelet factor 4 (PF4): implications for the pathogenesis of antiphospholipid syndrome. Blood. 2010;115(3):713-723.
    • (2010) Blood , vol.115 , Issue.3 , pp. 713-723
    • Sikara, M.P.1    Routsias, J.G.2    Samiotaki, M.3    Panayotou, G.4    Moutsopoulos, H.M.5    Vlachoyiannopoulos, P.G.6
  • 51
    • 80053295157 scopus 로고    scopus 로고
    • A diagnosis of heparin-induced thrombocytopenia with combined clinical and laboratory methods in cardiothoracic surgical intensive care unit patients
    • Demma LJ, Winkler AM, Levy JH. A diagnosis of heparin-induced thrombocytopenia with combined clinical and laboratory methods in cardiothoracic surgical intensive care unit patients. Anesth Analg. 2011;113(4):697-702.
    • (2011) Anesth Analg , vol.113 , Issue.4 , pp. 697-702
    • Demma, L.J.1    Winkler, A.M.2    Levy, J.H.3
  • 52
    • 45949112509 scopus 로고    scopus 로고
    • Quantitative interpretation of optical density measurements using PF4-dependent enzyme-immunoassays
    • DOI 10.1111/j.1538-7836.2008.03025.x
    • Warkentin TE, Sheppard JI, Moore JC, Sigouin CS, Kelton JG. Quantitative interpretation of optical density measurements using PF4-dependent enzymeimmunoassays. J Thromb Haemost. 2008;6(8): 1304-1312. (Pubitemid 352016309)
    • (2008) Journal of Thrombosis and Haemostasis , vol.6 , Issue.8 , pp. 1304-1312
    • Warkentin, T.E.1    Sheppard, J.I.2    Moore, J.C.3    Sigouin, C.S.4    Kelton, J.G.5
  • 53
    • 54049143619 scopus 로고    scopus 로고
    • A clinical-laboratory approach contributing to a rapid and reliable diagnosis of heparin-induced thrombocytopenia
    • Denys B, Stove V, Philippe J, Devreese K. A clinical- laboratory approach contributing to a rapid and reliable diagnosis of heparin-induced thrombocytopenia. Thromb Res. 2008;123(1):137-145.
    • (2008) Thromb Res , vol.123 , Issue.1 , pp. 137-145
    • Denys, B.1    Stove, V.2    Philippe, J.3    Devreese, K.4
  • 54
    • 13244268431 scopus 로고    scopus 로고
    • Thrombosis and ELISA optical density values in hospitalized patients with heparin-induced thrombocytopenia
    • DOI 10.1111/j.1538-7836.2004.01039.x
    • Zwicker JI, Uhl L, Huang WY, Shaz BH, Bauer KA. Thrombosis and ELISA optical density values in hospitalized patients with heparin-induced thrombocytopenia. J Thromb Haemost. 2004;2(12):2133-2137. (Pubitemid 40185772)
    • (2004) Journal of Thrombosis and Haemostasis , vol.2 , Issue.12 , pp. 2133-2137
    • Zwicker, J.I.1    Uhl, L.2    Huang, W.-Y.3    Shaz, B.H.4    Bauer, K.A.5
  • 55
    • 67949124723 scopus 로고    scopus 로고
    • Prospective evaluation of PF4/heparin immunoassays for the diagnosis of heparin-induced thrombocytopenia
    • Bakchoul T, Giptner A, Najaoui A, Bein G, Santoso S, Sachs UJ. Prospective evaluation of PF4/heparin immunoassays for the diagnosis of heparin-induced thrombocytopenia. J Thromb Haemost. 2009;7(8):1260-1265.
    • (2009) J Thromb Haemost , vol.7 , Issue.8 , pp. 1260-1265
    • Bakchoul, T.1    Giptner, A.2    Najaoui, A.3    Bein, G.4    Santoso, S.5    Sachs, U.J.6
  • 56
    • 77949445114 scopus 로고    scopus 로고
    • ASH evidence-based guidelines: Is the IgG-specific anti-PF4/heparin ELISA superior to the polyspecific ELISA in the laboratory diagnosis of HIT?
    • Cuker A, Ortel TL. ASH evidence-based guidelines: is the IgG-specific anti-PF4/heparin ELISA superior to the polyspecific ELISA in the laboratory diagnosis of HIT? Hematology Am Soc Hematol Educ Program. 2009;2009:250-252.
    • (2009) Hematology Am Soc Hematol Educ Program , vol.2009 , pp. 250-252
    • Cuker, A.1    Ortel, T.L.2
  • 57
    • 77956593113 scopus 로고    scopus 로고
    • Validation of the high-dose heparin confirmatory step for the diagnosis of heparin-induced thrombocytopenia
    • Whitlatch NL, Kong DF, Metjian AD, Arepally GM, Ortel TL. Validation of the high-dose heparin confirmatory step for the diagnosis of heparin-induced thrombocytopenia. Blood. 2010;116(10): 1761-1766.
    • (2010) Blood , vol.116 , Issue.10 , pp. 1761-1766
    • Whitlatch, N.L.1    Kong, D.F.2    Metjian, A.D.3    Arepally, G.M.4    Ortel, T.L.5
  • 58
    • 79960638918 scopus 로고    scopus 로고
    • Combined use of the high heparin step and optical density to optimize diagnostic sensitivity and specificity of an anti-PF4/heparin enzyme-immunoassay
    • Althaus K, Strobel U,Warkentin TE, Greinacher A. Combined use of the high heparin step and optical density to optimize diagnostic sensitivity and specificity of an anti-PF4/heparin enzyme-immunoassay. Thromb Res. 2011;128(3):256-260.
    • (2011) Thromb Res , vol.128 , Issue.3 , pp. 256-260
    • Althaus, K.1    Strobel, U.2    Warkentin, T.E.3    Greinacher, A.4
  • 59
    • 0022640930 scopus 로고
    • A Diagnostic test for heparin-induced thrombocytopenia
    • Sheridan D, Carter C, Kelton JG. A diagnostic test for heparin-induced thrombocytopenia. Blood. 1986;67(1):27-30. (Pubitemid 16167006)
    • (1986) Blood , vol.67 , Issue.1 , pp. 27-30
    • Sheridan, D.1    Carter, C.2    Kelton, J.G.3
  • 60
    • 0025951938 scopus 로고
    • A rapid and sensitive test for diagnosing heparin-associated thrombocytopenia
    • Greinacher A, Michels I, Kiefel V, Mueller- Eckhardt C. A rapid and sensitive test for diagnosing heparin-associated thrombocytopenia. Thromb Haemost. 1991;66(6):734-736.
    • (1991) Thromb Haemost , vol.66 , Issue.6 , pp. 734-736
    • Greinacher, A.1    Michels, I.2    Kiefel, V.3    Mueller-Eckhardt, C.4
  • 61
    • 36949007618 scopus 로고    scopus 로고
    • Laboratory testing for heparin-induced thrombocytopenia is inconsistent in North America: A survey of North American specialized coagulation laboratories
    • DOI 10.1160/TH07-06-0401
    • Price EA, Hayward CP, Moffat KA, Moore JC, Warkentin TE, Zehnder JL. Laboratory testing for heparin-induced thrombocytopenia is inconsistent in North America: a survey of North American specialized coagulation laboratories. Thromb Haemost. 2007;98(6):1357-1361. (Pubitemid 350239110)
    • (2007) Thrombosis and Haemostasis , vol.98 , Issue.6 , pp. 1357-1361
    • Price, E.A.1    Hayward, C.P.M.2    Moffat, K.A.3    Moore, J.C.4    Warkentin, T.E.5    Zehnder, J.L.6
  • 62
    • 0034254793 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia with thromboembolic complications: Meta-analysis of 2 prospective trials to assess the value of parenteral treatment with lepirudin and its therapeutic aPTT range
    • Greinacher A, Eichler P, Lubenow N, Kwasny H, Luz M. Heparin-induced thrombocytopenia with thromboembolic complications: a meta-analysis of 2 prospective trials to assess the value of parenteral treatment with lepirudin and its therapeutic aPTT range. Blood. 2000;96(3):846-851. (Pubitemid 30616845)
    • (2000) Blood , vol.96 , Issue.3 , pp. 846-851
    • Greinacher, A.1    Eichler, P.2    Lubenow, N.3    Kwasny, H.4    Luz, M.5
  • 63
    • 45949103154 scopus 로고    scopus 로고
    • Treatment and prevention of heparin-induced thrombocytopenia: American College of Chest Physicians evidence-based clinical practice guidelines (8th edition)
    • DOI 10.1378/chest.08-0677
    • Warkentin TE, Greinacher A, Koster A, et al. Treatment and prevention of heparin-induced thrombocytopenia: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Ed). Chest. 2008;133(suppl):340S-380S. (Pubitemid 351892970)
    • (2008) Chest , vol.133 , Issue.6 SUPPL. 6
    • Warkentin, T.E.1    Greinacher, A.2    Koster, A.3    Lincoff, A.M.4
  • 64
    • 84857024569 scopus 로고    scopus 로고
    • Current and emerging therapeutics for heparin-induced thrombocytopenia
    • Cuker A. Current and emerging therapeutics for heparin-induced thrombocytopenia. Semin Thromb Hemost. 2012;38(1):31-37.
    • (2012) Semin Thromb Hemost , vol.38 , Issue.1 , pp. 31-37
    • Cuker, A.1
  • 65
    • 0038285887 scopus 로고    scopus 로고
    • Argatroban anticoagulation in patients with heparin-induced thrombocytopenia
    • DOI 10.1001/archinte.163.15.1849
    • Lewis BE, Wallis DE, Leya F, et al. Argatroban anticoagulation in patients with heparin-induced thrombocytopenia. Arch Intern Med. 2003; 163(15):1849-1856. (Pubitemid 36960936)
    • (2003) Archives of Internal Medicine , vol.163 , Issue.15 , pp. 1849-1856
    • Lewis, B.E.1    Wallis, D.E.2    Leya, F.3    Hursting, M.J.4    Kelton, J.G.5
  • 68
    • 33745173460 scopus 로고    scopus 로고
    • Effects of argatroban therapy, demographic variables, and platelet count on thrombotic risks in heparin-induced thrombocytopenia
    • DOI 10.1378/chest.129.6.1407
    • Lewis BE, Wallis DE, Hursting MJ, Levine RL, Leya F. Effects of argatroban therapy, demographic variables, and platelet count on thrombotic risk in heparin-induced thrombocytopenia. Chest. 2006;129(6):1407-1416. (Pubitemid 43894967)
    • (2006) Chest , vol.129 , Issue.6 , pp. 1407-1416
    • Lewis, B.E.1    Wallis, D.E.2    Hursting, M.J.3    Levine, R.L.4    Leya, F.5
  • 71
    • 28444447383 scopus 로고    scopus 로고
    • Lepirudin in patients with heparin-induced thrombocytopenia - Results of the third prospective study (HAT-3) and a combined analysis of HAT-1, HAT-2, and HAT-3
    • DOI 10.1111/j.1538-7836.2005.01623.x
    • Lubenow N, Eichler P, Lietz T, et al. Lepirudin in patients with heparin-induced thrombocytopenia: results of the third prospective study (HAT-3) and a combined analysis of HAT-1, HAT-2, and HAT-3. J Thromb Haemost. 2005;3(11):2428-2436. (Pubitemid 41727158)
    • (2005) Journal of Thrombosis and Haemostasis , vol.3 , Issue.11 , pp. 2428-2436
    • Lubenow, N.1    Eichler, P.2    Lietz, T.3    Greinacher, A.4
  • 73
    • 0033527370 scopus 로고    scopus 로고
    • Generation of anti-hirudin antibodies in heparin-induced thrombocytopenic patients treated with r-hirudin
    • Song X, Huhle G, Wang L, Hoffmann U, Harenberg J. Generation of antihirudin antibodies in heparin-induced thrombocytopenic patients treated with r-hirudin. Circulation. 1999;100(14): 1528-1532. (Pubitemid 29461465)
    • (1999) Circulation , vol.100 , Issue.14 , pp. 1528-1532
    • Song, X.1    Huhle, G.2    Wang, L.3    Hoffmann, U.4    Harenberg, J.5
  • 74
    • 0034307370 scopus 로고    scopus 로고
    • Antihirudin antibodies in patients with heparin-induced thrombocytopenia treated with lepirudin: Incidence, effects on aPTT, and clinical relevance
    • Eichler P, Friesen HJ, Lubenow N, Jaeger B, Greinacher A. Antihirudin antibodies in patients with heparin-induced thrombocytopenia treated with lepirudin: incidence, effects on aPTT, and clinical relevance. Blood. 2000;96(7):2373-2378.
    • (2000) Blood , vol.96 , Issue.7 , pp. 2373-2378
    • Eichler, P.1    Friesen, H.J.2    Lubenow, N.3    Jaeger, B.4    Greinacher, A.5
  • 75
    • 0242381320 scopus 로고    scopus 로고
    • Anaphylactic and Anaphylactoid Reactions Associated With Lepirudin in Patients With Heparin-Induced Thrombocytopenia
    • DOI 10.1161/01.CIR.0000096056.37269.14
    • Greinacher A, Lubenow N, Eichler P. Anaphylactic and anaphylactoid reactions associated with lepirudin in patients with heparin-induced thrombocytopenia. Circulation. 2003;108(17):2062-2065. (Pubitemid 37337579)
    • (2003) Circulation , vol.108 , Issue.17 , pp. 2062-2065
    • Greinacher, A.1    Lubenow, N.2    Eichler, P.3
  • 76
    • 0035206428 scopus 로고    scopus 로고
    • Bivalirudin versus heparin during coronary angioplasty for unstable or postinfarction angina: Final report reanalysis of the Bivalirudin Angioplasty Study
    • Bittl JA, Chaitman BR, Feit F, Kimball W, Topol EJ. Bivalirudin versus heparin during coronary angioplasty for unstable or postinfarction angina: final report reanalysis of the Bivalirudin Angioplasty Study. Am Heart J. 2001;142(6):952- 959.
    • (2001) Am Heart J , vol.142 , Issue.6 , pp. 952-959
    • Bittl, J.A.1    Chaitman, B.R.2    Feit, F.3    Kimball, W.4    Topol, E.J.5
  • 77
    • 33644586875 scopus 로고    scopus 로고
    • A comparison of bivalirudin to heparin with protamine reversal in patients undergoing cardiac surgery with cardiopulmonary bypass: The EVOLUTION- On study
    • Dyke CM, Smedira NG, Koster A, et al. A comparison of bivalirudin to heparin with protamine reversal in patients undergoing cardiac surgery with cardiopulmonary bypass: the EVOLUTION- ON study. J Thorac Cardiovasc Surg. 2006; 131(3):533-539.
    • (2006) J Thorac Cardiovasc Surg , vol.131 , Issue.3 , pp. 533-539
    • Dyke, C.M.1    Smedira, N.G.2    Koster, A.3
  • 78
    • 33749048590 scopus 로고    scopus 로고
    • Bivalirudin provides rapid, effective, and reliable anticoagulation during off-pump coronary revascularization: Results of the "EVOLUTION OFF" trial
    • DOI 10.1213/01.ane.0000226098.95698.0f, PII 0000053920060900000004
    • Koster A, Spiess B, Jurmann M, et al. Bivalirudin provides rapid, effective, and reliable anticoagulation during off-pump coronary revascularization: results of the "EVOLUTION OFF" trial. Anesth Analg. 2006;103(3):540-544. (Pubitemid 44542900)
    • (2006) Anesthesia and Analgesia , vol.103 , Issue.3 , pp. 540-544
    • Koster, A.1    Spiess, B.2    Jurmann, M.3    Dyke, C.M.4    Smedira, N.G.5    Aronson, S.6    Lincoff, M.A.7
  • 79
    • 33645694284 scopus 로고    scopus 로고
    • Evaluation of bivalirudin treatment for heparin-induced thrombocytopenia in critically ill patients with hepatic and/or renal dysfunction
    • Kiser TH, Fish DN. Evaluation of bivalirudin treatment for heparin-induced thrombocytopenia in critically ill patients with hepatic and/or renal dysfunction. Pharmacotherapy. 2006;26(4):452-460.
    • (2006) Pharmacotherapy , vol.26 , Issue.4 , pp. 452-460
    • Kiser, T.H.1    Fish, D.N.2
  • 80
    • 78751650013 scopus 로고    scopus 로고
    • A randomized, open-label pilot study comparing desirudin and argatroban in patients with suspected heparin-induced thrombocytopenia with or without thrombosis
    • Boyce SW, Bandyk DF, Bartholomew JR, Frame JN, Rice L. A randomized, open-label pilot study comparing desirudin and argatroban in patients with suspected heparin-induced thrombocytopenia with or without thrombosis. Am J Ther. 2011;18(1):14-22.
    • (2011) Am J Ther , vol.18 , Issue.1 , pp. 14-22
    • Boyce, S.W.1    Bandyk, D.F.2    Bartholomew, J.R.3    Frame, J.N.4    Rice, L.5
  • 82
    • 0034966778 scopus 로고    scopus 로고
    • A comparison of danaparoid and lepirudin in heparin-induced thrombocytopenia
    • Farner B, Eichler P, Kroll H, Greinacher A. A comparison of danaparoid and lepirudin in heparin-induced thrombocytopenia. Thromb Haemost. 2001;85(6):950-957. (Pubitemid 32573742)
    • (2001) Thrombosis and Haemostasis , vol.85 , Issue.6 , pp. 950-957
    • Farner, B.1    Eichler, P.2    Kroll, H.3    Greinacher, A.4
  • 83
    • 33745297395 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia (HIT). A report of 1,478 clinical outcomes of patients treated with danaparoid (Orgaran) from 1982 to mid-2004
    • DOI 10.1160/TH05-07-0489
    • Magnani HN, Gallus A. Heparin-induced thrombocytopenia (HIT): a report of 1,478 clinical outcomes of patients treated with danaparoid (Orgaran) from 1982 to mid-2004. Thromb Haemost. 2006;95(6):967-981. (Pubitemid 43933754)
    • (2006) Thrombosis and Haemostasis , vol.95 , Issue.6 , pp. 967-981
    • Magnani, H.N.1    Gallus, A.2
  • 84
    • 78049443734 scopus 로고    scopus 로고
    • Fondaparinux: Does it cause HIT? Can it treat HIT?
    • Warkentin TE. Fondaparinux: does it cause HIT? Can it treat HIT? Expert Rev Hematol. 2010;3(5): 567-581.
    • (2010) Expert Rev Hematol , vol.3 , Issue.5 , pp. 567-581
    • Warkentin, T.E.1
  • 85
    • 82755189073 scopus 로고    scopus 로고
    • Fondaparinux in acute heparin-induced thrombocytopenia: A case series
    • Goldfarb MJ, Blostein M. Fondaparinux in acute heparin-induced thrombocytopenia: a case series. J Thromb Haemost. 2011;9(12):2501-2503.
    • (2011) J Thromb Haemost , vol.9 , Issue.12 , pp. 2501-2503
    • Goldfarb, M.J.1    Blostein, M.2
  • 86
    • 82755189078 scopus 로고    scopus 로고
    • Fondaparinux treatment of acute heparin-induced thrombocytopenia confirmed by serotonin-release assay: A 30-month, 16-patient case series
    • Warkentin TE, Pai M, Sheppard JI, Schulman S, Spyropoulos AC, Eikelboom JW. Fondaparinux treatment of acute heparin-induced thrombocytopenia confirmed by serotonin-release assay: a 30-month, 16-patient case series. J Thromb Haemost. 2011;9(12):2389-2396.
    • (2011) J Thromb Haemost , vol.9 , Issue.12 , pp. 2389-2396
    • Warkentin, T.E.1    Pai, M.2    Sheppard, J.I.3    Schulman, S.4    Spyropoulos, A.C.5    Eikelboom, J.W.6
  • 87
    • 80051532509 scopus 로고    scopus 로고
    • Prevalence and risk of pre-existing heparin-induced thrombocytopenia antibodies in patients with acute venous thromboembolism
    • Warkentin TE, Davidson BL, Buller HR, et al. Prevalence and risk of pre-existing heparin-induced thrombocytopenia antibodies in patients with acute venous thromboembolism. Chest. 2011;140(2):366-373.
    • (2011) Chest , vol.140 , Issue.2 , pp. 366-373
    • Warkentin, T.E.1    Davidson, B.L.2    Buller, H.R.3
  • 88
    • 78751649594 scopus 로고    scopus 로고
    • IgGclass anti-PF4/heparin antibodies and symptomatic DVT in orthopedic surgery patients receiving different antithromboembolic prophylaxis therapeutics
    • Motokawa S, Torigoshi T, Maeda Y, et al. IgGclass anti-PF4/heparin antibodies and symptomatic DVT in orthopedic surgery patients receiving different antithromboembolic prophylaxis therapeutics. BMC Musculoskelet Disord. 2011;12:22.
    • (2011) BMC Musculoskelet Disord , vol.12 , pp. 22
    • Motokawa, S.1    Torigoshi, T.2    Maeda, Y.3
  • 89
    • 79951912865 scopus 로고    scopus 로고
    • Impact of a pharmacist-directed anticoagulation service on the quality and safety of heparin-induced thrombocytopenia management
    • To L, Schillig JM, Desmet BD, Kuriakose P, Szandzik EG, Kalus JS. Impact of a pharmacist-directed anticoagulation service on the quality and safety of heparin-induced thrombocytopenia management. Ann Pharmacother. 2011;45(2): 195-200.
    • (2011) Ann Pharmacother , vol.45 , Issue.2 , pp. 195-200
    • To, L.1    Schillig, J.M.2    Desmet, B.D.3    Kuriakose, P.4    Szandzik, E.G.5    Kalus, J.S.6
  • 90
    • 84858016744 scopus 로고    scopus 로고
    • Unlike heparins newer oral anticoagulants do not interact with HIT antibodies and maybe useful in the long-term anticoagulant management of heparin compromised patients
    • abstracts. Abstract 2317
    • Lewis BE, Aranda C, Lewis M, Hoppensteadt D, Walenga JM, Fareed J. Unlike heparins newer oral anticoagulants do not interact with HIT antibodies and maybe useful in the long-term anticoagulant management of heparin compromised patients [abstracts]. Am Soc Hematol Educ Program. 2011;118(21):Abstract 2317.
    • (2011) Am Soc Hematol Educ Program , vol.118 , Issue.21
    • Lewis, B.E.1    Aranda, C.2    Lewis, M.3    Hoppensteadt, D.4    Walenga, J.M.5    Fareed, J.6
  • 91
    • 59449084599 scopus 로고    scopus 로고
    • Risk factors for major bleeding in patients with heparin-induced thrombocytopenia treated with argatroban: A retrospective study
    • Hursting MJ, Verme-Gobboney CN. Risk factors for major bleeding in patients with heparin-induced thrombocytopenia treated with argatroban: a retrospective study. J Cardiovasc Pharmacol. 2008;52(6):561-566.
    • (2008) J Cardiovasc Pharmacol , vol.52 , Issue.6 , pp. 561-566
    • Hursting, M.J.1    Verme-Gobboney, C.N.2
  • 92
    • 84856600313 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: In vitro studies on the interaction of dabigatran, rivaroxaban, and low-sulfated heparin, with platelet factor 4 and anti-PF4/heparin antibodies
    • Krauel K, Hackbarth C, Furll B, Greinacher A. Heparin-induced thrombocytopenia: in vitro studies on the interaction of dabigatran, rivaroxaban, and low-sulfated heparin, with platelet factor 4 and anti-PF4/heparin antibodies. Blood. 2012; 119(5):1248-1255.
    • (2012) Blood , vol.119 , Issue.5 , pp. 1248-1255
    • Krauel, K.1    Hackbarth, C.2    Furll, B.3    Greinacher, A.4
  • 93
    • 84858011224 scopus 로고    scopus 로고
    • Rational design and characterization of platelet factor 4 antagonists
    • abstract. Abstract 724
    • Sachais BS, Rux AH, Hinds JL, Rux JJ. Rational design and characterization of platelet factor 4 antagonists [abstract]. Am Soc Hematol Educ Program. 2010;116(21):Abstract 724.
    • (2010) Am Soc Hematol Educ Program , vol.116 , Issue.21
    • Sachais, B.S.1    Rux, A.H.2    Hinds, J.L.3    Rux, J.J.4
  • 94
    • 79951849374 scopus 로고    scopus 로고
    • PRT-060318, a novel syk inhibitor, prevents heparin-induced thrombocytopenia and thrombosis in a transgenic mouse model
    • Reilly MP, Sinha U, Andre P, et al. PRT-060318, a novel syk inhibitor, prevents heparin-induced thrombocytopenia and thrombosis in a transgenic mouse model. Blood. 2011;117(7):2241-2246.
    • (2011) Blood , vol.117 , Issue.7 , pp. 2241-2246
    • Reilly, M.P.1    Sinha, U.2    Andre, P.3
  • 95
    • 80053397337 scopus 로고    scopus 로고
    • The Syk-kinase inhibitor R406 impairs platelet activation and monocyte tissue factor expression triggered by heparin-PF4 complex directed antibodies
    • Lhermusier T, van Rottem J, Garcia C, et al. The Syk-kinase inhibitor R406 impairs platelet activation and monocyte tissue factor expression triggered by heparin-PF4 complex directed antibodies. J Thromb Haemost. 2011;9(10):2067-2076.
    • (2011) J Thromb Haemost , vol.9 , Issue.10 , pp. 2067-2076
    • Lhermusier, T.1    Van Rottem, J.2    Garcia, C.3
  • 96
    • 79961004062 scopus 로고    scopus 로고
    • CalDAG-GEFI deficiency protects mice in a novel model of FcgammaRIIA-mediated thrombosis and thrombocytopenia
    • Stolla M, Stefanini L, Andre P, et al. CalDAG-GEFI deficiency protects mice in a novel model of FcgammaRIIA-mediated thrombosis and thrombocytopenia. Blood. 2011;118(4):1113-1120.
    • (2011) Blood , vol.118 , Issue.4 , pp. 1113-1120
    • Stolla, M.1    Stefanini, L.2    Andre, P.3
  • 97
    • 65349161009 scopus 로고    scopus 로고
    • The costs of heparin-induced thrombocytopenia: A patient-based cost of illness analysis
    • Wilke T, Tesch S, Scholz A, Kohlmann T, Greinacher A. The costs of heparin-induced thrombocytopenia: a patient-based cost of illness analysis. J Thromb Haemost. 2009;7(5):766-773.
    • (2009) J Thromb Haemost , vol.7 , Issue.5 , pp. 766-773
    • Wilke, T.1    Tesch, S.2    Scholz, A.3    Kohlmann, T.4    Greinacher, A.5
  • 99
    • 0035082406 scopus 로고    scopus 로고
    • Interpreting the international normalized ratio (INR) in individuals receiving argatroban and warfarin
    • Sheth SB, DiCicco RA, Hursting MJ, Montague T, Jorkasky DK. Interpreting the International Normalized Ratio (INR) in individuals receiving argatroban and warfarin. Thromb Haemost. 2001; 85(3):435-440. (Pubitemid 32233014)
    • (2001) Thrombosis and Haemostasis , vol.85 , Issue.3 , pp. 435-440
    • Sheth, S.B.1    DiCicco, R.A.2    Hursting, M.J.3    Montague, T.4    Jorkasky, D.K.5
  • 100
    • 0032826601 scopus 로고    scopus 로고
    • Lower limb veins should be systematically explored in patients with isolated heparin-induced thrombocytopenia [5]
    • Tardy B, Tardy-Poncet B, Fournel P, Venet C, Jospe R, Dacosta A. Lower limb veins should be systematically explored in patients with isolated heparin-induced thrombocytopenia. Thromb Haemost. 1999;82(3):1199-1200. (Pubitemid 29419746)
    • (1999) Thrombosis and Haemostasis , vol.82 , Issue.3 , pp. 1199-1200
    • Tardy, B.1    Tardy-Poncet, B.2    Fournel, P.3    Venet, C.4    Jospe, R.5    Dacosta, A.6
  • 101
    • 77954521462 scopus 로고    scopus 로고
    • Outcomes after platelet transfusion in patients with heparin-induced thrombocytopenia
    • Refaai MA, Chuang C, Menegus M, Blumberg N, Francis CW. Outcomes after platelet transfusion in patients with heparin-induced thrombocytopenia. J Thromb Haemost. 2010;8(6):1419-1421.
    • (2010) J Thromb Haemost , vol.8 , Issue.6 , pp. 1419-1421
    • Refaai, M.A.1    Chuang, C.2    Menegus, M.3    Blumberg, N.4    Francis, C.W.5
  • 102
    • 52949118429 scopus 로고    scopus 로고
    • Platelet transfusions in heparin-induced thrombocytopenia: A report of four cases and review of the literature
    • Hopkins CK, Goldfinger D. Platelet transfusions in heparin-induced thrombocytopenia: a report of four cases and review of the literature. Transfusion. 2008;48(10):2128-2132.
    • (2008) Transfusion , vol.48 , Issue.10 , pp. 2128-2132
    • Hopkins, C.K.1    Goldfinger, D.2
  • 103
    • 0034680004 scopus 로고    scopus 로고
    • Use of heparin during cardiopulmonary bypass in patients with a history of heparin-induced thrombocytopenia [6]
    • DOI 10.1056/NEJM200008173430718
    • Potzsch B, Klovekorn WP, Madlener K. Use of heparin during cardiopulmonary bypass in patients with a history of heparin-induced thrombocytopenia. N Engl J Med. 2000;343(7):515. (Pubitemid 30646499)
    • (2000) New England Journal of Medicine , vol.343 , Issue.7 , pp. 515
    • Potzsch, B.1    Klovekorn, W.-P.2    Madlener, K.3
  • 104
    • 58149160052 scopus 로고    scopus 로고
    • Management of anticoagulation in patients with sub acute heparin-induced thrombocytopenia scheduled for heart transplantation
    • Selleng S, Haneya A, Hirt S, Selleng K, Schmid C, Greinacher A. Management of anticoagulation in patients with sub acute heparin-induced thrombocytopenia scheduled for heart transplantation. Blood. 2008;112(10):4024-4027.
    • (2008) Blood , vol.112 , Issue.10 , pp. 4024-4027
    • Selleng, S.1    Haneya, A.2    Hirt, S.3    Selleng, K.4    Schmid, C.5    Greinacher, A.6
  • 105
    • 51349096894 scopus 로고    scopus 로고
    • Heparininduced antibodies and cardiovascular risk in patients on dialysis
    • Asmis LM, Segal JB, Plantinga LC, et al. Heparininduced antibodies and cardiovascular risk in patients on dialysis. Thromb Haemost. 2008;100(3): 498-504.
    • (2008) Thromb Haemost , vol.100 , Issue.3 , pp. 498-504
    • Asmis, L.M.1    Segal, J.B.2    Plantinga, L.C.3
  • 106
    • 34248573447 scopus 로고    scopus 로고
    • The prevalence of antibodies to the platelet factor 4 -heparin complex and association with access thrombosis in patients on chronic hemodialysis
    • DOI 10.1016/j.thromres.2006.09.014, PII S0049384806003859
    • Carrier M, Knoll GA, Kovacs MJ, Moore JC, Fergusson D, Rodger MA. The prevalence of antibodies to the platelet factor 4-heparin complex and association with access thrombosis in patients on chronic hemodialysis. Thromb Res. 2007;120(2):215-220. (Pubitemid 46754417)
    • (2007) Thrombosis Research , vol.120 , Issue.2 , pp. 215-220
    • Carrier, M.1    Knoll, G.A.2    Kovacs, M.J.3    Moore, J.C.4    Fergusson, D.5    Rodger, M.A.6


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