Orbit-infiltrating mast cells, monocytes, and macrophages produce PDGF isoforms that orchestrate orbital fibroblast activation in graves' ophthalmopathy

Journal of Clinical Endocrinology and Metabolism

Volumn 97, Issue 3, 2012, Pages

  Van Steensel, L ^a   Paridaens, D ^b   Van Meurs, M ^a   Van Hagen, P M ^a   Van Den Bosch, W A ^b   Kuijpers, R W A M ^a   Drexhage, H A ^a   Hooijkaas, H ^a   Dik, Willem A ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b ROTTERDAM EYE HOSPITAL   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

HYALURONIC ACID; IMATINIB; INTERLEUKIN 6; MESSENGER RNA; NEUTRALIZING ANTIBODY; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR AA; PLATELET DERIVED GROWTH FACTOR AB; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PLATELET DERIVED GROWTH FACTOR C; PLATELET DERIVED GROWTH FACTOR D;

ARTICLE; B LYMPHOCYTE; CELL ACTIVATION; CELL ACTIVITY; CELL COUNT; CELL INFILTRATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENDOCRINE OPHTHALMOPATHY; ENZYME INHIBITION; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; MACROPHAGE; MAST CELL; MONOCYTE; ORBIT; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; T LYMPHOCYTE; TISSUE LEVEL;

CELL PROLIFERATION; EYE; FIBROBLASTS; GRAVES OPHTHALMOPATHY; HUMANS; HYALURONIC ACID; INTERLEUKIN-6; MACROPHAGES; MAST CELLS; MONOCYTES; PIPERAZINES; PLATELET-DERIVED GROWTH FACTOR; PROTEIN KINASE INHIBITORS; PYRIMIDINES;

EID: 84858046995     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2011-2697     Document Type: Article

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