Phosphorylation as a method of tuning the enantiodiscrimination potency of quinine-An NMR study

Chirality

Volumn 24, Issue 4, 2012, Pages 318-328

  Gõrecki, Łukasz ^a   Berlicki, Łukasz ^a   Mucha, Artur ^a   Kafarski, Paweł ^a   Łlepokura, Katarzyna ^b   Rudzińska Szostak, Ewa ^a  

^a WROCLAW UNIVERSITY OF TECHNOLOGY   (Poland)

^b UNIVERSITY OF WROC AW   (Poland)

Author keywords

alkaloids; chiral auxiliaries; conformation analysis; NMR spectroscopy; phosphorylation

Indexed keywords

9 O DIETHYLPHOSPHORYLQUININE; 9 O DIPHENYLPHOSPHORYLQUININE; AMINO ACID DERIVATIVE; BIPHENYL DERIVATIVE; DICHLOROMETHANE; HYDROXYL GROUP; LIGAND; NITRO DERIVATIVE; PHOSPHATE; QUININE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CHIRALITY; CRYSTAL STRUCTURE; DRUG CONFORMATION; DRUG POTENCY; DRUG SYNTHESIS; ENANTIOSELECTIVITY; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PHOSPHORYLATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT; STEREOCHEMISTRY; TEMPERATURE DEPENDENCE; VALIDATION PROCESS;

MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PHOSPHORYLATION; PROTONS; QUININE; STEREOISOMERISM; SUBSTRATE SPECIFICITY; TEMPERATURE;

EID: 84858031477     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.22000     Document Type: Article

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