Detection of endogenous K-ras mRNA in living cells at a single base resolution by a PNA molecular beacon

Molecular Pharmaceutics

Volumn 9, Issue 3, 2012, Pages 685-693

  Kam, Yossi ^a   Rubinstein, Abraham ^a,b   Nissan, Aviram ^c   Halle, David ^c   Yavin, Eylon ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

hybridization; in vivo imaging; KRAS oncogene; molecular beacon; mRNA; peptide nucleic acids

Indexed keywords

DNA; MESSENGER RNA; PEPTIDE NUCLEIC ACID;

ARTICLE; CODON; CONTROLLED STUDY; DNA SYNTHESIS; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOLECULAR BEACON; NUCLEIC ACID SYNTHESIS; ONCOGENE K RAS; POINT MUTATION; PRIORITY JOURNAL; RNA ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

CELL LINE, TUMOR; DNA PROBES; HT29 CELLS; HUMANS; NUCLEIC ACID HYBRIDIZATION; PEPTIDE NUCLEIC ACIDS; PROTO-ONCOGENE PROTEINS; RAS PROTEINS; RNA, MESSENGER;

EID: 84858019925     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200505k     Document Type: Article

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