Application of a whole-body pharmacokinetic model for targeted radionuclide therapy to NM404 and FLT

Physics in Medicine and Biology

Volumn 57, Issue 6, 2012, Pages 1641-1657

  Grudzinski, Joseph J ^a   Floberg, John M ^a   Mudd, Sarah R ^b   Jeffery, Justin J ^c   Peterson, Eric T ^a   Nomura, Alice ^a   Burnette, Ronald R ^b   Tomé, Wolfgang A ^a   Weichert, Jamey P ^a   Jeraj, Robert ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACCURACY AND PRECISION; ACCURATE MEASUREMENT; BLOOD POOL; CLEARANCE RATES; CORRELATION COEFFICIENT; CRAMER RAO LOWER BOUND; ELIMINATION RATE; MODEL ACCURACY; MURINE MODEL; OPTIMAL SAMPLING; PARAMETER SENSITIVITIES; PHARMACOKINETIC MODEL; PK VALUES; REGIONS OF INTEREST; SAMPLING SCHEDULE; STANDARD DEVIATION; STANDARD ERRORS; TARGETED RADIONUCLIDE THERAPIES; TIME POINTS; WHOLE-BODY;

DOSIMETRY; ESTIMATION; MOLECULAR IMAGING; OPTIMIZATION; PARAMETER ESTIMATION; PHARMACOKINETICS; RATE CONSTANTS;

TUMORS;

18 (4 IODOPHENYL)OCTADECYLPHOSPHOCHOLINE; 18-(4-IODOPHENYL)OCTADECYLPHOSPHOCHOLINE; 2',3' DIDEOXYNUCLEOSIDE DERIVATIVE; 3' FLUOROTHYMIDINE; DRUG DERIVATIVE; FLUORINE; PHOSPHORYLCHOLINE; RADIOACTIVE IODINE; RADIOPHARMACEUTICAL AGENT;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; BIOPHYSICS; COMPUTER ASSISTED RADIOTHERAPY; EXPERIMENTAL NEOPLASM; HUMAN; METABOLISM; METHODOLOGY; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NUDE MOUSE; RADIOTHERAPY; SCINTISCANNING; STATISTICAL MODEL; STATISTICS;

ANIMALS; BIOPHYSICAL PHENOMENA; DIDEOXYNUCLEOSIDES; FLUORINE RADIOISOTOPES; HUMANS; IODINE RADIOISOTOPES; MICE; MICE, NUDE; MODELS, BIOLOGICAL; MODELS, STATISTICAL; NEOPLASMS, EXPERIMENTAL; PHOSPHORYLCHOLINE; POSITRON-EMISSION TOMOGRAPHY AND COMPUTED TOMOGRAPHY; RADIOPHARMACEUTICALS; RADIOTHERAPY; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; X-RAY MICROTOMOGRAPHY;

EID: 84858019920     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/57/6/1641     Document Type: Article

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