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Volumn 40, Issue 2, 1996, Pages 331-335

The anti-human immunodeficiency virus agent 3′-fluorothymidine induces DNA damage and apoptosis in human lymphoblastoid cells

Author keywords

[No Author keywords available]

Indexed keywords

3' FLUOROTHYMIDINE; ANTIVIRUS AGENT; DNA FRAGMENT; RALURIDINE; THYMIDINE DERIVATIVE; ZIDOVUDINE;

EID: 0030071471     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.40.2.331     Document Type: Article
Times cited : (24)

References (27)
  • 1
    • 0025247903 scopus 로고
    • Apoptosis, the role of the endonuclease
    • Arends, M. J., R. G. Morris, and A. H. Wyllie. 1990. Apoptosis, the role of the endonuclease. Am. J Pathol 136:593-608.
    • (1990) Am. J Pathol , vol.136 , pp. 593-608
    • Arends, M.J.1    Morris, R.G.2    Wyllie, A.H.3
  • 2
    • 0027168859 scopus 로고
    • Apoptosis and its modulation in human promyelocytic HL-60 cells treated with DNA topoisomerase I and II inhibitors
    • Bertrand, R., E. Solary, J. Jenkins, and Y. Pommier. 1993. Apoptosis and its modulation in human promyelocytic HL-60 cells treated with DNA topoisomerase I and II inhibitors. Exp. Cell Res. 207:388-397.
    • (1993) Exp. Cell Res. , vol.207 , pp. 388-397
    • Bertrand, R.1    Solary, E.2    Jenkins, J.3    Pommier, Y.4
  • 3
    • 0026483281 scopus 로고
    • Variations in patterns of DNA damage induced in human colorectal tumor cells by 5-fluorodeoxyuridine, implications for mechanisms of resistance and cytotoxicity Proc
    • Canman, C. E., H.-Y. Tang, D. P. Normolle, T. S. Lawrence, and J. Maybaum. 1992 Variations in patterns of DNA damage induced in human colorectal tumor cells by 5-fluorodeoxyuridine, implications for mechanisms of resistance and cytotoxicity Proc. Natl. Acad. Sci. USA 89:10474-10478.
    • (1992) Natl. Acad. Sci. USA , vol.89 , pp. 10474-10478
    • Canman, C.E.1    Tang, H.-Y.2    Normolle, D.P.3    Lawrence, T.S.4    Maybaum, J.5
  • 4
    • 0024381627 scopus 로고
    • Delayed cytotoxicity and selective loss of mitochondrial DNA in cells treated with the anti-human immunodeficiency virus compound 2′,3′-dideoxycytidine
    • Chen, C. H., and Y.-C. Cheng. 1989. Delayed cytotoxicity and selective loss of mitochondrial DNA in cells treated with the anti-human immunodeficiency virus compound 2′,3′-dideoxycytidine. J. Biol. Chem. 264:11934-11937.
    • (1989) J. Biol. Chem. , vol.264 , pp. 11934-11937
    • Chen, C.H.1    Cheng, Y.-C.2
  • 5
    • 0025729392 scopus 로고
    • Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity
    • Chen, C.-H., M. Vazquez-Padua, and Y.-C. Cheng. 1991. Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity. Mol. Pharmacol. 39:625-628.
    • (1991) Mol. Pharmacol. , vol.39 , pp. 625-628
    • Chen, C.-H.1    Vazquez-Padua, M.2    Cheng, Y.-C.3
  • 8
    • 0026032318 scopus 로고
    • Anti-human immunodeficiency virus synergism by zidovudine (3′-azidothymidine) and didanosine (dideoxyinosine) contrasts with their additive inhibition of normal human marrow progenitor cells
    • Dornsife, R. E., M. H. St. Clair, A. T. Huang, T. J. Panella, G. W. Kozalka, C. L. Burns, and D. R. Averett. 1991. Anti-human immunodeficiency virus synergism by zidovudine (3′-azidothymidine) and didanosine (dideoxyinosine) contrasts with their additive inhibition of normal human marrow progenitor cells Antimicrob. Agents Chemother. 35:322-328.
    • (1991) Antimicrob. Agents Chemother. , vol.35 , pp. 322-328
    • Dornsife, R.E.1    St. Clair, M.H.2    Huang, A.T.3    Panella, T.J.4    Kozalka, G.W.5    Burns, C.L.6    Averett, D.R.7
  • 9
    • 0028216549 scopus 로고
    • Effects of 2′,3′-dideoxynucleosides on proliferation and differentiation of human pluripotent progenitois in liquid culture and their effects on mitochondrial DNA synthesis
    • Faraj, A., D. A. Fowler, E. G. Bridges, and J.-P. Sommadossi. 1994 Effects of 2′,3′-dideoxynucleosides on proliferation and differentiation of human pluripotent progenitois in liquid culture and their effects on mitochondrial DNA synthesis. Antimicrob. Agents Chemother. 38:924-930.
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 924-930
    • Faraj, A.1    Fowler, D.A.2    Bridges, E.G.3    Sommadossi, J.-P.4
  • 12
    • 0001513802 scopus 로고
    • DNA strand breaks occurring during apoptosis-their early in situ detection by terminal deoxy-nucleotidyl transferase and nick translation assays and prevention by serine protease inhibitors
    • Gorzyca, W., S. Bruno, R. J. Darzynkiewicz, J. Gong, and Z. Darzynkiewicz. 1992 DNA strand breaks occurring during apoptosis-their early in situ detection by terminal deoxy-nucleotidyl transferase and nick translation assays and prevention by serine protease inhibitors. Int J. Oncol. 1:639-648.
    • (1992) Int J. Oncol. , vol.1 , pp. 639-648
    • Gorzyca, W.1    Bruno, S.2    Darzynkiewicz, R.J.3    Gong, J.4    Darzynkiewicz, Z.5
  • 13
    • 0029060757 scopus 로고
    • Fluarabine- and gemcitabine-induced apoptosis: Incorporation of analogs into DNA is a critical event
    • Huang, P., and W. Plunkett. 1995. Fluarabine- and gemcitabine-induced apoptosis: incorporation of analogs into DNA is a critical event. Cancer Chemother Pharmacol 36:181-188.
    • (1995) Cancer Chemother Pharmacol , vol.36 , pp. 181-188
    • Huang, P.1    Plunkett, W.2
  • 15
    • 0024850371 scopus 로고
    • Hydroxyurea increases the phosphorylation of 3′-fluorothymidine and 3′-azidothymidine in CEM cells
    • Karlsson, A., P. Reichard, and F. Eckstein. 1989. Hydroxyurea increases the phosphorylation of 3′-fluorothymidine and 3′-azidothymidine in CEM cells. Eur J. Biochem. 186:689-694
    • (1989) Eur J. Biochem. , vol.186 , pp. 689-694
    • Karlsson, A.1    Reichard, P.2    Eckstein, F.3
  • 16
    • 0024470862 scopus 로고
    • Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: A cautionary note
    • Kaufmann, S. H. 1989. Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note. Cancer Res. 49:5870-5878.
    • (1989) Cancer Res. , vol.49 , pp. 5870-5878
    • Kaufmann, S.H.1
  • 17
    • 0028329172 scopus 로고
    • Apoptosis, its significance in cancer and cancer therapy
    • Kerr, J. F. R. 1994. Apoptosis, its significance in cancer and cancer therapy. Cancer 73:2013-2026
    • (1994) Cancer , vol.73 , pp. 2013-2026
    • Kerr, J.F.R.1
  • 18
    • 0026509422 scopus 로고
    • Comparison of anti-human immunodeficiency virus activities, cellular transport, and plasma and intracellular pharmacokinetics of 3′-fluoro-3′-deoxythumidine and 3′-azido-3′-deoxythymidine
    • Kong, X.-B., G.-Y. Zhu, P. M. Vidal, K. A. Watanabe, B. Polsky, D. Armstrong, M. Ostrander, J. Lang S. A., E. Muchmore, and T.-C. Chou. 1992. Comparison of anti-human immunodeficiency virus activities, cellular transport, and plasma and intracellular pharmacokinetics of 3′-fluoro-3′-deoxythumidine and 3′-azido-3′-deoxythymidine. Antimicrob. Agents Chemother. 36:808-818.
    • (1992) Antimicrob. Agents Chemother. , vol.36 , pp. 808-818
    • Kong, X.-B.1    Zhu, G.-Y.2    Vidal, P.M.3    Watanabe, K.A.4    Polsky, B.5    Armstrong, D.6    Ostrander, M.7    Lang, J.8    Muchmore, S.A.E.9    Chou, T.-C.10
  • 19
    • 0027936767 scopus 로고
    • Induction of apoptosis in androgen-independent human prostate cancer cells undergoing thymine-less death
    • Kyprianou, N., A. K. Bains, and S. C. Jacobs. 1994. Induction of apoptosis in androgen-independent human prostate cancer cells undergoing thymine-less death. The Prostate 25:66-75.
    • (1994) The Prostate , vol.25 , pp. 66-75
    • Kyprianou, N.1    Bains, A.K.2    Jacobs, S.C.3
  • 20
    • 0028148674 scopus 로고
    • Effects of antiviral nucleoside analogs on human DNA polymerases and mitochondrial DNA synthesis
    • Martin, J. L., C. E. Brown, N. Matthews-Davis, and J. E. Reardon. 1994. Effects of antiviral nucleoside analogs on human DNA polymerases and mitochondrial DNA synthesis. Antimicrob. Agents Chemother. 38:2743-2749.
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 2743-2749
    • Martin, J.L.1    Brown, C.E.2    Matthews-Davis, N.3    Reardon, J.E.4
  • 22
    • 0028178394 scopus 로고
    • Identification of a 3′ to 5′ exonuclease that removes cytosine arabinoside monophosphate from 3′ termini of DNA
    • Perrino, F. W., H. Miller, and K. A. Ealey. 1994. Identification of a 3′ to 5′ exonuclease that removes cytosine arabinoside monophosphate from 3′ termini of DNA. J. Biol. Chem. 269:16357-16363.
    • (1994) J. Biol. Chem. , vol.269 , pp. 16357-16363
    • Perrino, F.W.1    Miller, H.2    Ealey, K.A.3
  • 23
    • 0028102003 scopus 로고
    • Regulation of apoptosis by low serum in cells of different stages of neoplastic progression: Enhanced susceptibility after loss of a senescence gene and decreased susceptibility after loss of a tumor suppressor gene
    • Preston, G. A., J. E. Lang, R. R. Maronpot, and J. C. Barrett. 1994. Regulation of apoptosis by low serum in cells of different stages of neoplastic progression: enhanced susceptibility after loss of a senescence gene and decreased susceptibility after loss of a tumor suppressor gene Cancer Res. 54:4214-4223.
    • (1994) Cancer Res. , vol.54 , pp. 4214-4223
    • Preston, G.A.1    Lang, J.E.2    Maronpot, R.R.3    Barrett, J.C.4
  • 25
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in single cells
    • Singh, N. P., M. T. McCoy, R. R. Tice, and E. L. Schneider. 1988. A simple technique for quantitation of low levels of DNA damage in single cells. Exp. Cell Res. 175:184-191.
    • (1988) Exp. Cell Res. , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.L.4
  • 26
    • 0028046038 scopus 로고
    • Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40
    • Vayssiere, J.-L., P. X. Petit, Y. Risler, and B. Mignotte. 1994. Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40. Proc Natl. Acad Sci USA 91:11752-11756.
    • (1994) Proc Natl. Acad Sci USA , vol.91 , pp. 11752-11756
    • Vayssiere, J.-L.1    Petit, P.X.2    Risler, Y.3    Mignotte, B.4
  • 27
    • 0021346318 scopus 로고
    • Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis
    • Wyllie, A., R. G. Morris, A. L. Smith, and D. Dunlop. 1984. Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis. J. Pathol 142:67-77.
    • (1984) J. Pathol , vol.142 , pp. 67-77
    • Wyllie, A.1    Morris, R.G.2    Smith, A.L.3    Dunlop, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.