Yield of routine molecular analyses in colorectal cancer patients ≤ 70 years to detect underlying lynch syndrome

Journal of Pathology

Volumn 226, Issue 5, 2012, Pages 764-774

  Van Lier, Margot G F ^a   Leenen, Celine H M ^a   Wagner, Anja ^a   Ramsoekh, Dewkoemar ^a   Dubbink, Hendrikus J ^a   Van Den Ouweland, Ans M W ^a   Westenend, Pieter J ^b   De Graaf, Eelco J R ^c   Wolters, Leonieke M M ^b   Vrijland, Wietske W ^d   Kuipers, Ernst J ^a   Van Leerdam, Monique E ^a   Steyerberg, Ewout W ^a   Dinjens, Winand N M ^a   Van Tilburg, G ^a   Hulspas, S ^a   Lange, J F ^a   Hoedemaeker, R F ^e   Bode, W A ^c   Van Dam, J H ^e   Wismans, P J ^f   Den Toom, R ^g   Van De Weijgert, E J H M ^g   Van Tilburg, A J P ^e   Lont, H E ^h   Van't Hoff, B W M ^h   Oostenbroek, R J ^b   Logeman, F ^e   Van Baalen, O ^e   Van Den Ingh, H F G M ⁱ   Van Der Harst, E ⁱ   Kubben, F J G M ⁱ   Weidema, W F ^j   Ouwendijk, R J Th ^j   Van Rijssel, R H ^k   Eddes, E H ^k   Ter Borg, F ^k   more..

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b ALBERT SCHWEITZER HOSPITAL   (Netherlands)

^c IJSSELLAND HOSPITAL   (Netherlands)

^d SINT FRANCISCUS GASTHUIS   (Netherlands)

^e Erasmus MC ^*  (Netherlands)

^f Havenziekenhuis   (Netherlands)

^g Ruwaard Van Putten Ziekenhuis   (Netherlands)

^h Vlietland Ziekenhuis   (Netherlands)

ⁱ Maasstad Hospital Rotterdam   (Netherlands)

^j IKAZIA HOSPITAL   (Netherlands)

^k DEVENTER HOSPITAL   (Netherlands)

more..

Author keywords

Colorectal cancer; Immunohistochemistry; Lynch syndrome; Microsatellite instability

Indexed keywords

MISMATCH REPAIR PROTEIN; PROTEIN MLH1;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER INVASION; CANCER PATIENT; COLORECTAL ADENOMA; COLORECTAL CANCER; FEMALE; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; MICROSATELLITE STABLE; MULTICENTER STUDY; PREDICTOR VARIABLE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN EXPRESSION; PROTEIN METHYLATION; TUMOR CLASSIFICATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOMA; AGE FACTORS; AGED; COLORECTAL NEOPLASMS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA METHYLATION; DNA MISMATCH REPAIR; DNA MUTATIONAL ANALYSIS; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; FEMALE; GENETIC TESTING; GERM-LINE MUTATION; HUMANS; IMMUNOHISTOCHEMISTRY; LOGISTIC MODELS; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; MUTS HOMOLOG 2 PROTEIN; NETHERLANDS; NUCLEAR PROTEINS; ODDS RATIO; PREDICTIVE VALUE OF TESTS; PROMOTER REGIONS, GENETIC; PROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS;

EID: 84857993554     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.3963     Document Type: Article

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