메뉴 건너뛰기




Volumn 24, Issue 2, 2010, Pages 139-149

Application of direct renin inhibition to chronic kidney disease

Author keywords

Aliskiren; Angiotensin; Kidney disease; Renin

Indexed keywords

ALDOSTERONE; ALDOSTERONE ANTAGONIST; ALISKIREN; AMLODIPINE; ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN I; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR ANTAGONIST; CALCIUM CHANNEL BLOCKING AGENT; CANDESARTAN; CAPTOPRIL; CREATININE; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; HYDROCHLOROTHIAZIDE; IRBESARTAN; LISINOPRIL; LOSARTAN; PLACEBO; PRORENIN; PRORENIN RECEPTOR; RAMIPRIL; RECEPTOR PROTEIN; RENIN; RENIN INHIBITOR; RENIN RECEPTOR; TELMISARTAN; UNCLASSIFIED DRUG; VALSARTAN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST;

EID: 77955415650     PISSN: 09203206     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10557-010-6232-1     Document Type: Review
Times cited : (31)

References (86)
  • 1
    • 0036176161 scopus 로고    scopus 로고
    • K/DOQI clinical practice guidelines for chronic kidney disease: Evaluation, classification, and stratification
    • K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis 2002; 39:S1-266.
    • (2002) Am J Kidney Dis , vol.39
  • 3
    • 33847748973 scopus 로고    scopus 로고
    • Prevalence of chronic kidney disease and associated risk factors-United States, 1999-2004
    • MMWR
    • MMWR 2007 Prevalence of chronic kidney disease and associated risk factors-United States, 1999-2004 Morb Mortal Wkly Rep 56 161 165
    • (2007) Morb Mortal Wkly Rep , vol.56 , pp. 161-165
  • 4
    • 77955427635 scopus 로고    scopus 로고
    • United States Renal Data System.Available at: www.usrds.org.
  • 5
    • 34948911363 scopus 로고    scopus 로고
    • End-stage renal disease in the United States: An update from the United States Renal Data System
    • DOI 10.1681/ASN.2007020220
    • RN Foley AJ Collins 2007 End-stage renal disease in the United States: an update from the United States Renal Data System J Am Soc Nephrol 18 2644 2648 10.1681/ASN.2007020220 17656472 (Pubitemid 47531190)
    • (2007) Journal of the American Society of Nephrology , vol.18 , Issue.10 , pp. 2644-2648
    • Foley, R.N.1    Collins, A.J.2
  • 6
    • 66749153764 scopus 로고    scopus 로고
    • Direct all-cause health care costs associated with chronic kidney disease in patients with diabetes and hypertension: A managed care perspective
    • 19422271
    • F Laliberte BK Bookhart F Vekeman, et al. 2009 Direct all-cause health care costs associated with chronic kidney disease in patients with diabetes and hypertension: a managed care perspective J Manag Care Pharm 15 312 322 19422271
    • (2009) J Manag Care Pharm , vol.15 , pp. 312-322
    • Laliberte, F.1    Bookhart, B.K.2    Vekeman, F.3
  • 7
    • 4644221457 scopus 로고    scopus 로고
    • Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
    • DOI 10.1056/NEJMoa041031
    • AS Go GM Chertow D Fan CE McCulloch CY Hsu 2004 Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization N Engl J Med 351 1296 1305 10.1056/NEJMoa041031 1:CAS:528:DC%2BD2cXnvFSgtr8%3D 15385656 (Pubitemid 39268908)
    • (2004) New England Journal of Medicine , vol.351 , Issue.13
    • Go, A.S.1    Chertow, G.M.2    Fan, D.3    McCulloch, C.E.4    Hsu, C.-Y.5
  • 8
    • 0027517659 scopus 로고
    • The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy
    • DOI 10.1056/NEJM199311113292004
    • EJ Lewis LG Hunsicker RP Bain RD Rohde 1993 The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The Collaborative Study Group N Engl J Med 329 1456 1462 10.1056/NEJM199311113292004 1:STN:280:DyaK2c%2FhvFKitQ%3D%3D 8413456 (Pubitemid 23335891)
    • (1993) New England Journal of Medicine , vol.329 , Issue.20 , pp. 1456-1462
    • Lewis, E.J.1    Hunsicker, L.G.2    Bain, R.P.3    Rohde, R.D.4
  • 9
    • 0035922447 scopus 로고    scopus 로고
    • Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
    • 10.1056/NEJMoa011303 1:CAS:528:DC%2BD3MXntlelsLg%3D 11565517
    • EJ Lewis LG Hunsicker WR Clarke, et al. 2001 Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes N Engl J Med 345 851 860 10.1056/NEJMoa011303 1:CAS:528:DC%2BD3MXntlelsLg%3D 11565517
    • (2001) N Engl J Med , vol.345 , pp. 851-860
    • Lewis, E.J.1    Hunsicker, L.G.2    Clarke, W.R.3
  • 10
    • 0035922441 scopus 로고    scopus 로고
    • Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
    • 10.1056/NEJMoa011161 1:CAS:528:DC%2BD3MXntlelsLk%3D 11565518
    • BM Brenner ME Cooper D de Zeeuw, et al. 2001 Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy N Engl J Med 345 861 869 10.1056/NEJMoa011161 1:CAS:528:DC%2BD3MXntlelsLk%3D 11565518
    • (2001) N Engl J Med , vol.345 , pp. 861-869
    • Brenner, B.M.1    Cooper, M.E.2    De Zeeuw, D.3
  • 11
    • 33845760213 scopus 로고    scopus 로고
    • KDOQI Clinical Practice Guidelines and Clinical Practice Recommendations for Diabetes and Chronic Kidney Disease
    • KDOQI Clinical Practice Guidelines and Clinical Practice Recommendations for Diabetes and Chronic Kidney Disease. Am J Kidney Dis 2007; 49:S12-154.
    • (2007) Am J Kidney Dis , vol.49
  • 12
    • 36248931664 scopus 로고    scopus 로고
    • The renin-angiotensin aldosterone system: Pathophysiological role and pharmacologic inhibition
    • 17970613
    • SA Atlas 2007 The renin-angiotensin aldosterone system: pathophysiological role and pharmacologic inhibition J Manag Care Pharm 13 9 20 17970613
    • (2007) J Manag Care Pharm , vol.13 , pp. 9-20
    • Atlas, S.A.1
  • 13
    • 0036073755 scopus 로고    scopus 로고
    • 1, 25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system
    • 1:CAS:528:DC%2BD38XlsVGlsbg%3D 12122115
    • YC Li J Kong M Wei, et al. 2002 1, 25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system J Clin Invest 110 229 238 1:CAS:528:DC%2BD38XlsVGlsbg%3D 12122115
    • (2002) J Clin Invest , vol.110 , pp. 229-238
    • Li, Y.C.1    Kong, J.2    Wei, M.3
  • 14
    • 0035723995 scopus 로고    scopus 로고
    • Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism
    • 10.1161/hy1101.092839 1:CAS:528:DC%2BD3MXovVOrsbg%3D 11711505
    • M Mazzali J Hughes YG Kim, et al. 2001 Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism Hypertension 38 1101 1106 10.1161/hy1101.092839 1:CAS:528:DC%2BD3MXovVOrsbg%3D 11711505
    • (2001) Hypertension , vol.38 , pp. 1101-1106
    • Mazzali, M.1    Hughes, J.2    Kim, Y.G.3
  • 15
    • 54349084035 scopus 로고    scopus 로고
    • Transforming growth factor-beta blockade down-regulates the renin-angiotensin system and modifies cardiac remodeling after myocardial infarction
    • 10.1210/en.2008-0165 1:CAS:528:DC%2BD1cXhtlWnsrfM 18653707
    • LJ Ellmers NJ Scott S Medicherla, et al. 2008 Transforming growth factor-beta blockade down-regulates the renin-angiotensin system and modifies cardiac remodeling after myocardial infarction Endocrinology 149 5828 5834 10.1210/en.2008-0165 1:CAS:528:DC%2BD1cXhtlWnsrfM 18653707
    • (2008) Endocrinology , vol.149 , pp. 5828-5834
    • Ellmers, L.J.1    Scott, N.J.2    Medicherla, S.3
  • 17
    • 52249086668 scopus 로고    scopus 로고
    • The renin-angiotensin system and diabetes: An update
    • 1:CAS:528:DC%2BD1cXht1Shur%2FK 19065996
    • A Ribeiro-Oliveira Jr AI Nogueira RM Pereira, et al. 2008 The renin-angiotensin system and diabetes: an update Vasc Health Risk Manag 4 787 803 1:CAS:528:DC%2BD1cXht1Shur%2FK 19065996
    • (2008) Vasc Health Risk Manag , vol.4 , pp. 787-803
    • Ribeiro-Oliveira Jr., A.1    Nogueira, A.I.2    Pereira, R.M.3
  • 18
    • 33644970894 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 and angiotensin-(1-7): An evolving story in cardiovascular regulation
    • 3 II DOI 10.1161/01.HYP.0000196268.08909.fb
    • CM Ferrario 2006 Angiotensin-converting enzyme 2 and angiotensin-(1-7): an evolving story in cardiovascular regulation Hypertension 47 515 521 10.1161/01.HYP.0000196268.08909.fb 1:CAS:528:DC%2BD28XhsFKlurc%3D 16365192 (Pubitemid 43843868)
    • (2006) Hypertension , vol.47 , pp. 515-521
    • Ferrario, C.M.1
  • 19
    • 33750722109 scopus 로고    scopus 로고
    • Glomerular localization and expression of angiotensin-converting enzyme 2 and angiotensin-converting enzyme: Implications for albuminuria in diabetes
    • DOI 10.1681/ASN.2006050423
    • M Ye J Wysocki J William, et al. 2006 Glomerular localization and expression of Angiotensin-converting enzyme 2 and Angiotensin-converting enzyme: implications for albuminuria in diabetes J Am Soc Nephrol 17 3067 3075 10.1681/ASN.2006050423 1:CAS:528:DC%2BD28Xht1yjtbrP 17021266 (Pubitemid 44707767)
    • (2006) Journal of the American Society of Nephrology , vol.17 , Issue.11 , pp. 3067-3075
    • Ye, M.1    Wysocki, J.2    William, J.3    Soler, M.J.4    Cokic, I.5    Batlle, D.6
  • 21
    • 33745845825 scopus 로고    scopus 로고
    • Physiology of local renin-angiotensin systems
    • DOI 10.1152/physrev.00036.2005
    • M Paul A Poyan Mehr R Kreutz 2006 Physiology of local renin-angiotensin systems Physiol Rev 86 747 803 10.1152/physrev.00036.2005 1:CAS:528: DC%2BD28XnsFGgtLk%3D 16816138 (Pubitemid 44033382)
    • (2006) Physiological Reviews , vol.86 , Issue.3 , pp. 747-803
    • Paul, M.1    Mehr, A.P.2    Kreutz, R.3
  • 22
    • 34748859681 scopus 로고    scopus 로고
    • The intrarenal renin-angiotensin system: From physiology to the pathobiology of hypertension and kidney disease
    • DOI 10.1124/pr.59.3.3
    • H Kobori M Nangaku LG Navar A Nishiyama 2007 The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease Pharmacol Rev 59 251 287 10.1124/pr.59.3.3 1:CAS:528:DC%2BD2sXht1ahsr3E 17878513 (Pubitemid 47481436)
    • (2007) Pharmacological Reviews , vol.59 , Issue.3 , pp. 251-287
    • Kobori, H.1    Nangaku, M.2    Navar, L.G.3    Nishiyama, A.4
  • 23
  • 24
    • 33750741932 scopus 로고    scopus 로고
    • Renin-angiotensin-aldosterone system and progression of renal disease
    • DOI 10.1681/ASN.2006040356
    • C Ruster G Wolf 2006 Renin-angiotensin-aldosterone system and progression of renal disease J Am Soc Nephrol 17 2985 2991 10.1681/ASN.2006040356 17035613 (Pubitemid 44707758)
    • (2006) Journal of the American Society of Nephrology , vol.17 , Issue.11 , pp. 2985-2991
    • Ruster, C.1    Wolf, G.2
  • 25
    • 0034896157 scopus 로고    scopus 로고
    • Aldosterone as a determinant of cardiovascular and renal dysfunction
    • 1:CAS:528:DC%2BD3MXntVKitrY%3D 11461980
    • M Epstein 2001 Aldosterone as a determinant of cardiovascular and renal dysfunction J R Soc Med 94 378 383 1:CAS:528:DC%2BD3MXntVKitrY%3D 11461980
    • (2001) J R Soc Med , vol.94 , pp. 378-383
    • Epstein, M.1
  • 26
    • 38549092093 scopus 로고    scopus 로고
    • Aldosterone and vascular inflammation
    • DOI 10.1161/HYPERTENSIONAHA.107.095489, PII 0000426820080200000001
    • NJ Brown 2008 Aldosterone and vascular inflammation Hypertension 51 161 167 10.1161/HYPERTENSIONAHA.107.095489 1:CAS:528:DC%2BD1cXmt1OhsQ%3D%3D 18172061 (Pubitemid 351159920)
    • (2008) Hypertension , vol.51 , Issue.2 , pp. 161-167
    • Brown, N.J.1
  • 27
    • 0034651798 scopus 로고    scopus 로고
    • Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure
    • 1:CAS:528:DC%2BD3cXhtlGntL4%3D 10673249
    • CA Farquharson AD Struthers 2000 Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure Circulation 101 594 597 1:CAS:528:DC%2BD3cXhtlGntL4%3D 10673249
    • (2000) Circulation , vol.101 , pp. 594-597
    • Farquharson, C.A.1    Struthers, A.D.2
  • 28
    • 0036266596 scopus 로고    scopus 로고
    • Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
    • 1:CAS:528:DC%2BD38XktlWlu78%3D 12045255
    • G Nguyen F Delarue C Burckle, et al. 2002 Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin J Clin Invest 109 1417 1427 1:CAS:528:DC%2BD38XktlWlu78%3D 12045255
    • (2002) J Clin Invest , vol.109 , pp. 1417-1427
    • Nguyen, G.1    Delarue, F.2    Burckle, C.3
  • 29
    • 77955413963 scopus 로고    scopus 로고
    • The increase in renin during renin inhibition: Does it result in harmful effects by the (pro)renin receptor?
    • [Epub ahead of print]
    • Danser AJ. The increase in renin during renin inhibition: does it result in harmful effects by the (pro)renin receptor? Hypertens Res 2009:[Epub ahead of print].
    • (2009) Hypertens Res
    • Danser, A.J.1
  • 30
    • 74849089254 scopus 로고    scopus 로고
    • Direct renin inhibition and the kidney
    • 10.1038/nrneph.2009.201 1:CAS:528:DC%2BD1MXhsFyiurfF 19935744
    • NK Hollenberg 2010 Direct renin inhibition and the kidney Nat Rev Nephrol 6 49 55 10.1038/nrneph.2009.201 1:CAS:528:DC%2BD1MXhsFyiurfF 19935744
    • (2010) Nat Rev Nephrol , vol.6 , pp. 49-55
    • Hollenberg, N.K.1
  • 31
    • 30944469631 scopus 로고    scopus 로고
    • Renin increases mesangial cell transforming growth factor-β1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms
    • DOI 10.1038/sj.ki.5000011, PII 5000011
    • Y Huang S Wongamorntham J Kasting, et al. 2006 Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms Kidney Int 69 105 113 10.1038/sj.ki.5000011 1:CAS:528:DC%2BD28Xpt1Wqtw%3D%3D 16374430 (Pubitemid 43117745)
    • (2006) Kidney International , vol.69 , Issue.1 , pp. 105-113
    • Huang, Y.1    Wongamorntham, S.2    Kasting, J.3    McQuillan, D.4    Owens, R.T.5    Yu, L.6    Noble, N.A.7    Border, W.8
  • 32
    • 77951499583 scopus 로고    scopus 로고
    • Moving Targets
    • Prorenin, Renin, and Their Receptor
    • Reudelhuber TL. Prorenin, Renin, and Their Receptor. Moving Targets. Hypertension 2010.
    • (2010) Hypertension
    • Reudelhuber, T.L.1
  • 35
    • 0032709804 scopus 로고    scopus 로고
    • The paradox of the low-renin state in diabetic nephropathy
    • 1:CAS:528:DyaK1MXnsVegsLk%3D 10541298
    • DA Price LE Porter M Gordon, et al. 1999 The paradox of the low-renin state in diabetic nephropathy J Am Soc Nephrol 10 2382 2391 1:CAS:528: DyaK1MXnsVegsLk%3D 10541298
    • (1999) J Am Soc Nephrol , vol.10 , pp. 2382-2391
    • Price, D.A.1    Porter, L.E.2    Gordon, M.3
  • 36
    • 17144469021 scopus 로고    scopus 로고
    • Renin-angiotensin system activation and interstitial inflammation in human diabetic nephropathy
    • 10.1046/j.1523-1755.64.s86.12.x 1:CAS:528:DC%2BD3sXot1Wis7w%3D 12969130
    • S Mezzano A Droguett ME Burgos, et al. 2003 Renin-angiotensin system activation and interstitial inflammation in human diabetic nephropathy Kidney Int Suppl 86 S64 70 10.1046/j.1523-1755.64.s86.12.x 1:CAS:528: DC%2BD3sXot1Wis7w%3D 12969130
    • (2003) Kidney Int Suppl , vol.86 , pp. 64-70
    • Mezzano, S.1    Droguett, A.2    Burgos, M.E.3
  • 37
    • 0022544541 scopus 로고
    • Therapeutic advantage of converting enzyme inhibitors in arresting progressive renal disease associated with systemic hypertension in the rat
    • 10.1172/JCI112528 1:CAS:528:DyaL28XktFyit7g%3D 3011863
    • S Anderson HG Rennke BM Brenner 1986 Therapeutic advantage of converting enzyme inhibitors in arresting progressive renal disease associated with systemic hypertension in the rat J Clin Invest 77 1993 2000 10.1172/JCI112528 1:CAS:528:DyaL28XktFyit7g%3D 3011863
    • (1986) J Clin Invest , vol.77 , pp. 1993-2000
    • Anderson, S.1    Rennke, H.G.2    Brenner, B.M.3
  • 38
    • 15844368318 scopus 로고    scopus 로고
    • Effect of the angiotensin-converting-enzyme inhibitor benazepril on the progression of chronic renal insufficiency
    • DOI 10.1056/NEJM199604113341502
    • G Maschio D Alberti G Janin, et al. 1996 Effect of the angiotensin-converting-enzyme inhibitor benazepril on the progression of chronic renal insufficiency. The Angiotensin-Converting-Enzyme Inhibition in Progressive Renal Insufficiency Study Group N Engl J Med 334 939 945 10.1056/NEJM199604113341502 1:CAS:528:DyaK28XislKmsbg%3D 8596594 (Pubitemid 26114159)
    • (1996) New England Journal of Medicine , vol.334 , Issue.15 , pp. 939-945
    • Maschio, G.1    Alberti, D.2    Janin, G.3    Locatelli, F.4    Mann, J.F.E.5    Motolese, M.6    Ponticelli, C.7    Ritz, E.8    Zucchelli, P.9
  • 39
    • 11144294678 scopus 로고    scopus 로고
    • Salt intake and progression of chronic kidney disease: An overlooked modifiable exposure? A commentary
    • DOI 10.1053/j.ajkd.2004.08.041, PII S0272638604013101
    • MR Weir JC Fink 2005 Salt intake and progression of chronic kidney disease: an overlooked modifiable exposure? A commentary Am J Kidney Dis 45 176 188 10.1053/j.ajkd.2004.08.041 15696458 (Pubitemid 40038059)
    • (2005) American Journal of Kidney Diseases , vol.45 , Issue.1 , pp. 176-188
    • Weir, M.R.1    Fink, J.C.2
  • 40
    • 20044392697 scopus 로고    scopus 로고
    • Angiotensin-I converting enzyme insertion/deletion polymorphism and its association with diabetic nephropathy: A meta-analysis of studies reported between 1994 and 2004 and comprising 14,727 subjects
    • DOI 10.1007/s00125-005-1726-2
    • DP Ng BC Tai D Koh KW Tan KS Chia 2005 Angiotensin-I converting enzyme insertion/deletion polymorphism and its association with diabetic nephropathy: a meta-analysis of studies reported between 1994 and 2004 and comprising 14, 727 subjects Diabetologia 48 1008 1016 10.1007/s00125-005-1726-2 1:CAS:528:DC%2BD2MXktFyhtr8%3D 15830182 (Pubitemid 40767996)
    • (2005) Diabetologia , vol.48 , Issue.5 , pp. 1008-1016
    • Ng, D.P.K.1    Tai, B.C.2    Koh, D.3    Tan, K.W.4    Chia, K.S.5
  • 41
    • 44349177550 scopus 로고    scopus 로고
    • ACE gene polymorphism and losartan treatment in type 2 diabetic patients with nephropathy
    • 10.1681/ASN.2007050582 1:CAS:528:DC%2BD1cXkvFOhtrw%3D 18199798
    • HH Parving D de Zeeuw ME Cooper, et al. 2008 ACE gene polymorphism and losartan treatment in type 2 diabetic patients with nephropathy J Am Soc Nephrol 19 771 779 10.1681/ASN.2007050582 1:CAS:528:DC%2BD1cXkvFOhtrw%3D 18199798
    • (2008) J Am Soc Nephrol , vol.19 , pp. 771-779
    • Parving, H.H.1    De Zeeuw, D.2    Cooper, M.E.3
  • 42
    • 53749103611 scopus 로고    scopus 로고
    • Angiotensin converting enzyme insertion/deletion polymorphism and renoprotection in diabetic and nondiabetic nephropathies
    • 10.2215/CJN.04140907 18550651
    • P Ruggenenti P Bettinaglio F Pinares G Remuzzi 2008 Angiotensin converting enzyme insertion/deletion polymorphism and renoprotection in diabetic and nondiabetic nephropathies Clin J Am Soc Nephrol 3 1511 1525 10.2215/CJN.04140907 18550651
    • (2008) Clin J Am Soc Nephrol , vol.3 , pp. 1511-1525
    • Ruggenenti, P.1    Bettinaglio, P.2    Pinares, F.3    Remuzzi, G.4
  • 43
    • 15944366224 scopus 로고    scopus 로고
    • The renin-angiotensin-aldosterone system, glucose metabolism and diabetes
    • DOI 10.1016/j.tem.2005.02.003
    • G Giacchetti LA Sechi S Rilli RM Carey 2005 The renin-angiotensin- aldosterone system, glucose metabolism and diabetes Trends Endocrinol Metab 16 120 126 10.1016/j.tem.2005.02.003 1:CAS:528:DC%2BD2MXivV2gs7o%3D 15808810 (Pubitemid 40432462)
    • (2005) Trends in Endocrinology and Metabolism , vol.16 , Issue.3 , pp. 120-126
    • Giacchetti, G.1    Sechi, L.A.2    Rilli, S.3    Carey, R.M.4
  • 44
    • 0033989542 scopus 로고    scopus 로고
    • Clinical implications of increased plasma angiotensin II despite ACE inhibitor therapy in patients with congestive heart failure
    • DOI 10.1053/euhj.1999.1740
    • E Roig F Perez-Villa M Morales, et al. 2000 Clinical implications of increased plasma angiotensin II despite ACE inhibitor therapy in patients with congestive heart failure Eur Heart J 21 53 57 10.1053/euhj.1999.1740 1:CAS:528:DC%2BD3cXpt1ygtQ%3D%3D 10610744 (Pubitemid 30042669)
    • (2000) European Heart Journal , vol.21 , Issue.1 , pp. 53-57
    • Roig, E.1    Perez-Villa, F.2    Morales, M.3    Jimenez, W.4    Orus, J.5    Heras, M.6    Sanz, G.7
  • 45
    • 0037967318 scopus 로고    scopus 로고
    • Chymase is upregulated in diabetic nephropathy: Implications for an alternative pathway of angiotensin II-mediated diabetic renal and vascular disease
    • DOI 10.1097/01.ASN.0000071512.93927.4E
    • XR Huang WY Chen LD Truong HY Lan 2003 Chymase is upregulated in diabetic nephropathy: implications for an alternative pathway of angiotensin II-mediated diabetic renal and vascular disease J Am Soc Nephrol 14 1738 1747 10.1097/01.ASN.0000071512.93927.4E 1:CAS:528:DC%2BD3sXksV2ju78%3D 12819233 (Pubitemid 36750469)
    • (2003) Journal of the American Society of Nephrology , vol.14 , Issue.7 , pp. 1738-1747
    • Huang, X.R.1    Chen, W.Y.2    Truong, L.D.3    Lan, H.Y.4
  • 46
    • 2642575030 scopus 로고    scopus 로고
    • Combined blockade of the renin-angiotensin system with angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists
    • DOI 10.1161/01.CIR.0000131449.94713.AD
    • M Azizi J Menard 2004 Combined blockade of the renin-angiotensin system with angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists Circulation 109 2492 2499 10.1161/01.CIR.0000131449.94713.AD 15173039 (Pubitemid 38720545)
    • (2004) Circulation , vol.109 , Issue.21 , pp. 2492-2499
    • Azizi, M.1    Menard, J.2
  • 47
    • 0034685168 scopus 로고    scopus 로고
    • Angiotensin II receptor antagonists
    • 10.1016/S0140-6736(99)10365-9 1:CAS:528:DC%2BD3cXhvVGjsr4%3D 10696996
    • M Burnier HR Brunner 2000 Angiotensin II receptor antagonists Lancet 355 637 645 10.1016/S0140-6736(99)10365-9 1:CAS:528:DC%2BD3cXhvVGjsr4%3D 10696996
    • (2000) Lancet , vol.355 , pp. 637-645
    • Burnier, M.1    Brunner, H.R.2
  • 48
    • 0141789624 scopus 로고    scopus 로고
    • Progression of chronic kidney disease: The role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition: A patient-level meta-analysis
    • 1:CAS:528:DC%2BD3sXnt12kurs%3D 12965979
    • TH Jafar PC Stark CH Schmid, et al. 2003 Progression of chronic kidney disease: the role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition: a patient-level meta-analysis Ann Intern Med 139 244 252 1:CAS:528:DC%2BD3sXnt12kurs%3D 12965979
    • (2003) Ann Intern Med , vol.139 , pp. 244-252
    • Jafar, T.H.1    Stark, P.C.2    Schmid, C.H.3
  • 50
    • 0034627208 scopus 로고    scopus 로고
    • Randomised controlled trial of dual blockade of renin-angiotensin system in patients with hypertension, microalbuminuria, and non-insulin dependent diabetes: The candesartan and lisinopril microalbuminuria (CALM) study
    • 10.1136/bmj.321.7274.1440 1:CAS:528:DC%2BD3MXjsFCkuw%3D%3D 11110735
    • CE Mogensen S Neldam I Tikkanen, et al. 2000 Randomised controlled trial of dual blockade of renin-angiotensin system in patients with hypertension, microalbuminuria, and non-insulin dependent diabetes: the candesartan and lisinopril microalbuminuria (CALM) study BMJ 321 1440 1444 10.1136/bmj.321.7274. 1440 1:CAS:528:DC%2BD3MXjsFCkuw%3D%3D 11110735
    • (2000) BMJ , vol.321 , pp. 1440-1444
    • Mogensen, C.E.1    Neldam, S.2    Tikkanen, I.3
  • 51
    • 49149087718 scopus 로고    scopus 로고
    • Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): A multicentre, randomised, double-blind, controlled trial
    • 10.1016/S0140-6736(08)61236-2 1:CAS:528:DC%2BD1cXpvFKgsLs%3D 18707986
    • JF Mann RE Schmieder M McQueen, et al. 2008 Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): a multicentre, randomised, double-blind, controlled trial Lancet 372 547 553 10.1016/S0140-6736(08)61236-2 1:CAS:528:DC%2BD1cXpvFKgsLs%3D 18707986
    • (2008) Lancet , vol.372 , pp. 547-553
    • Mann, J.F.1    Schmieder, R.E.2    McQueen, M.3
  • 53
    • 49149131161 scopus 로고    scopus 로고
    • Renin-angiotensin blockade and kidney disease
    • 10.1016/S0140-6736(08)61212-X 18707969
    • PA Sarafidis GL Bakris 2008 Renin-angiotensin blockade and kidney disease Lancet 372 511 512 10.1016/S0140-6736(08)61212-X 18707969
    • (2008) Lancet , vol.372 , pp. 511-512
    • Sarafidis, P.A.1    Bakris, G.L.2
  • 54
    • 66849128220 scopus 로고    scopus 로고
    • Design of combination angiotensin receptor blocker and angiotensin-converting enzyme inhibitor for treatment of diabetic nephropathy (VA NEPHRON-D)
    • 10.2215/CJN.03350708 1:CAS:528:DC%2BD1MXjslagur8%3D 19118120
    • LF Fried W Duckworth JH Zhang, et al. 2009 Design of combination angiotensin receptor blocker and angiotensin-converting enzyme inhibitor for treatment of diabetic nephropathy (VA NEPHRON-D) Clin J Am Soc Nephrol 4 361 368 10.2215/CJN.03350708 1:CAS:528:DC%2BD1MXjslagur8%3D 19118120
    • (2009) Clin J Am Soc Nephrol , vol.4 , pp. 361-368
    • Fried, L.F.1    Duckworth, W.2    Zhang, J.H.3
  • 55
    • 39449104268 scopus 로고    scopus 로고
    • Protocol of the Long-term Impact of RAS Inhibition on Cardiorenal Outcomes (LIRICO) randomized trial
    • 1:CAS:528:DC%2BD1cXlvVGru78%3D 18046666
    • A Maione A Nicolucci JC Craig, et al. 2007 Protocol of the Long-term Impact of RAS Inhibition on Cardiorenal Outcomes (LIRICO) randomized trial J Nephrol 20 646 655 1:CAS:528:DC%2BD1cXlvVGru78%3D 18046666
    • (2007) J Nephrol , vol.20 , pp. 646-655
    • Maione, A.1    Nicolucci, A.2    Craig, J.C.3
  • 57
    • 30944466929 scopus 로고    scopus 로고
    • Enhanced renoprotective effects of ultrahigh doses of irbesartan in patients with type 2 diabetes and microalbuminuria
    • DOI 10.1111/j.1523-1755.2005.00511.x, PII 4494697
    • K Rossing KJ Schjoedt BR Jensen F Boomsma HH Parving 2005 Enhanced renoprotective effects of ultrahigh doses of irbesartan in patients with type 2 diabetes and microalbuminuria Kidney Int 68 1190 1198 10.1111/j.1523-1755.2005. 00511.x 1:CAS:528:DC%2BD2MXhtVCjt73E 16105050 (Pubitemid 43246436)
    • (2005) Kidney International , vol.68 , Issue.3 , pp. 1190-1198
    • Rossing, K.1    Schjoedt, K.J.2    Jensen, B.R.3    Boomsma, F.4    Parving, H.-H.5
  • 58
    • 65249126924 scopus 로고    scopus 로고
    • Supramaximal dose of candesartan in proteinuric renal disease
    • 10.1681/ASN.2008040416 1:CAS:528:DC%2BD1MXltFyjsro%3D 19211712
    • E Burgess N Muirhead P Rene de Cotret, et al. 2009 Supramaximal dose of candesartan in proteinuric renal disease J Am Soc Nephrol 20 893 900 10.1681/ASN.2008040416 1:CAS:528:DC%2BD1MXltFyjsro%3D 19211712
    • (2009) J Am Soc Nephrol , vol.20 , pp. 893-900
    • Burgess, E.1    Muirhead, N.2    Rene De Cotret, P.3
  • 59
    • 12144252958 scopus 로고    scopus 로고
    • Aldosterone escape during blockade of the renin-angiotensin-aldosterone system in diabetic nephropathy is associated with enhanced decline in glomerular filtration rate
    • DOI 10.1007/s00125-004-1542-0
    • KJ Schjoedt S Andersen P Rossing L Tarnow HH Parving 2004 Aldosterone escape during blockade of the renin-angiotensin-aldosterone system in diabetic nephropathy is associated with enhanced decline in glomerular filtration rate Diabetologia 47 1936 1939 10.1007/s00125-004-1542-0 1:CAS:528:DC%2BD2cXhtVOqs7vJ 15551047 (Pubitemid 40110201)
    • (2004) Diabetologia , vol.47 , Issue.11 , pp. 1936-1939
    • Schjoedt, K.J.1    Andersen, S.2    Rossing, P.3    Tarnow, L.4    Parving, H.-H.5
  • 60
    • 37349065141 scopus 로고    scopus 로고
    • Aldosterone and progression of renal disease
    • 1:CAS:528:DC%2BD1cXhtFKiu78%3D 18090669
    • U Wenzel 2008 Aldosterone and progression of renal disease Curr Opin Nephrol Hypertens 17 44 50 1:CAS:528:DC%2BD1cXhtFKiu78%3D 18090669
    • (2008) Curr Opin Nephrol Hypertens , vol.17 , pp. 44-50
    • Wenzel, U.1
  • 61
    • 66149131479 scopus 로고    scopus 로고
    • Aldosterone antagonists for preventing the progression of chronic kidney disease: A systematic review and meta-analysis
    • 10.2215/CJN.04750908 1:CAS:528:DC%2BD1MXktFKis78%3D 19261819
    • SD Navaneethan SU Nigwekar AR Sehgal GF Strippoli 2009 Aldosterone antagonists for preventing the progression of chronic kidney disease: a systematic review and meta-analysis Clin J Am Soc Nephrol 4 542 551 10.2215/CJN.04750908 1:CAS:528:DC%2BD1MXktFKis78%3D 19261819
    • (2009) Clin J Am Soc Nephrol , vol.4 , pp. 542-551
    • Navaneethan, S.D.1    Nigwekar, S.U.2    Sehgal, A.R.3    Strippoli, G.F.4
  • 62
    • 33845302661 scopus 로고    scopus 로고
    • Long-term effects of spironolactone on proteinuria and kidney function in patients with chronic kidney disease
    • 1:CAS:528:DC%2BD28Xht1Kju7bL 17035949
    • S Bianchi R Bigazzi VM Campese 2006 Long-term effects of spironolactone on proteinuria and kidney function in patients with chronic kidney disease Kidney Int 70 2116 2123 1:CAS:528:DC%2BD28Xht1Kju7bL 17035949
    • (2006) Kidney Int , vol.70 , pp. 2116-2123
    • Bianchi, S.1    Bigazzi, R.2    Campese, V.M.3
  • 63
    • 0036372173 scopus 로고    scopus 로고
    • Angiotensin II suppression in humans by the orally active renin inhibitor aliskiren (SPP100): Comparison with enalapril
    • 10.1161/hy0102.102293 1:CAS:528:DC%2BD38XpvVyktA%3D%3D 11799102
    • J Nussberger G Wuerzner C Jensen HR Brunner 2002 Angiotensin II suppression in humans by the orally active renin inhibitor aliskiren (SPP100): comparison with enalapril Hypertension 39 E1 8 10.1161/hy0102.102293 1:CAS:528:DC%2BD38XpvVyktA%3D%3D 11799102
    • (2002) Hypertension , vol.39 , pp. 1-8
    • Nussberger, J.1    Wuerzner, G.2    Jensen, C.3    Brunner, H.R.4
  • 64
    • 36248931230 scopus 로고    scopus 로고
    • Antihypertensive efficacy of the oral direct renin inhibitor aliskiren as add-on therapy in patients not responding to amlodipine monotherapy
    • Rafique Essop M, et al. 10.1111/j.1524-6175.2007.06614.x 1:CAS:528:DC%2BD2sXht12rt7%2FK
    • W Drummond MA Munger 2007 Rafique Essop M, et al. Antihypertensive efficacy of the oral direct renin inhibitor aliskiren as add-on therapy in patients not responding to amlodipine monotherapy J Clin Hypertens (Greenwich) 9 742 750 10.1111/j.1524-6175.2007.06614.x 1:CAS:528:DC%2BD2sXht12rt7%2FK
    • (2007) J Clin Hypertens (Greenwich) , vol.9 , pp. 742-750
    • Drummond, W.1    Munger, M.A.2
  • 65
    • 33845366982 scopus 로고    scopus 로고
    • Renin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazide
    • DOI 10.1097/HJH.0b013e3280103a6b, PII 0000487220070100000030
    • A Villamil SG Chrysant D Calhoun, et al. 2007 Renin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazide J Hypertens 25 217 226 10.1097/HJH.0b013e3280103a6b 1:CAS:528:DC%2BD28Xht1OhtrnM 17143194 (Pubitemid 44885684)
    • (2007) Journal of Hypertension , vol.25 , Issue.1 , pp. 217-226
    • Villamil, A.1    Chrysant, S.G.2    Calhoun, D.3    Schober, B.4    Hsu, H.5    Matrisciano-Dimichino, L.6    Zhang, J.7
  • 67
    • 34447521458 scopus 로고    scopus 로고
    • Efficacy and safety of combined use of aliskiren and valsartan in patients with hypertension: A randomised, double-blind trial
    • DOI 10.1016/S0140-6736(07)61124-6, PII S0140673607611246
    • S Oparil SA Yarows S Patel, et al. 2007 Efficacy and safety of combined use of aliskiren and valsartan in patients with hypertension: a randomised, double-blind trial Lancet 370 221 229 10.1016/S0140-6736(07)61124-6 1:CAS:528:DC%2BD2sXnvF2gsrc%3D 17658393 (Pubitemid 47069535)
    • (2007) Lancet , vol.370 , Issue.9583 , pp. 221-229
    • Oparil, S.1    Yarows, S.A.2    Patel, S.3    Fang, H.4    Zhang, J.5    Satlin, A.6
  • 68
    • 9644287897 scopus 로고    scopus 로고
    • Pharmacologic demonstration of the synergistic effects of a combination of the renin inhibitor aliskiren and the AT1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption
    • DOI 10.1097/01.ASN.0000146686.35541.29
    • M Azizi J Menard A Bissery, et al. 2004 Pharmacologic demonstration of the synergistic effects of a combination of the renin inhibitor aliskiren and the AT1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption J Am Soc Nephrol 15 3126 3133 10.1097/01.ASN.0000146686.35541.29 15579516 (Pubitemid 39578845)
    • (2004) Journal of the American Society of Nephrology , vol.15 , Issue.12 , pp. 3126-3133
    • Azizi, M.1    Menard, J.2    Bissery, A.3    Guyenne, T.-T.4    Bura-Riviere, A.5    Vaidyanathan, S.6    Camisasca, R.P.7
  • 69
    • 34548818515 scopus 로고    scopus 로고
    • Hormonal and hemodynamic effects of aliskiren and valsartan and their combination in sodium-replete normotensive individuals
    • 10.2215/CJN.00360107 1:CAS:528:DC%2BD2sXhsVGqt73K 17702736
    • M Azizi J Menard A Bissery TT Guyene A Bura-Riviere 2007 Hormonal and hemodynamic effects of aliskiren and valsartan and their combination in sodium-replete normotensive individuals Clin J Am Soc Nephrol 2 947 955 10.2215/CJN.00360107 1:CAS:528:DC%2BD2sXhsVGqt73K 17702736
    • (2007) Clin J Am Soc Nephrol , vol.2 , pp. 947-955
    • Azizi, M.1    Menard, J.2    Bissery, A.3    Guyene, T.T.4    Bura-Riviere, A.5
  • 70
    • 70349690296 scopus 로고    scopus 로고
    • Renal effects of aliskiren compared with and in combination with irbesartan in patients with type 2 diabetes, hypertension, and albuminuria
    • 10.2337/dc09-0168 1:CAS:528:DC%2BD1MXhtlehs7nL
    • F Persson P Rossing H Reinhard, et al. 2009 Renal effects of aliskiren compared with and in combination with irbesartan in patients with type 2 diabetes, hypertension, and albuminuria Diab Care 32 1873 1879 10.2337/dc09-0168 1:CAS:528:DC%2BD1MXhtlehs7nL
    • (2009) Diab Care , vol.32 , pp. 1873-1879
    • Persson, F.1    Rossing, P.2    Reinhard, H.3
  • 71
    • 47049093197 scopus 로고    scopus 로고
    • Renal and hormonal responses to direct renin inhibition with aliskiren in healthy humans
    • 10.1161/CIRCULATIONAHA.108.767202 1:CAS:528:DC%2BD1cXnt1ehs70%3D 18559696
    • ND Fisher AH Jan Danser J Nussberger WP Dole NK Hollenberg 2008 Renal and hormonal responses to direct renin inhibition with aliskiren in healthy humans Circulation 117 3199 3205 10.1161/CIRCULATIONAHA.108.767202 1:CAS:528: DC%2BD1cXnt1ehs70%3D 18559696
    • (2008) Circulation , vol.117 , pp. 3199-3205
    • Fisher, N.D.1    Jan Danser, A.H.2    Nussberger, J.3    Dole, W.P.4    Hollenberg, N.K.5
  • 72
    • 77949528492 scopus 로고    scopus 로고
    • Aliskiren/valsartan combination for the treatment of cardiovascular and renal diseases
    • 10.1586/erc.09.143 1:CAS:528:DC%2BD1MXhsFKgu7jN 20030022
    • SA Yarows 2010 Aliskiren/valsartan combination for the treatment of cardiovascular and renal diseases Expert Rev Cardiovasc Ther 8 19 33 10.1586/erc.09.143 1:CAS:528:DC%2BD1MXhsFKgu7jN 20030022
    • (2010) Expert Rev Cardiovasc Ther , vol.8 , pp. 19-33
    • Yarows, S.A.1
  • 73
    • 79958249630 scopus 로고    scopus 로고
    • Effect of the oral direct renin inhibitor aliskiren in patients with symptomatic heart failure
    • 10.1161/CIRCHEARTFAILURE.107.740704 1:CAS:528:DC%2BD1cXosFGnsLY%3D 19808266
    • JJ McMurray B Pitt R Latini, et al. 2008 Effect of the oral direct renin inhibitor aliskiren in patients with symptomatic heart failure Circ Heart Fail 1 17 24 10.1161/CIRCHEARTFAILURE.107.740704 1:CAS:528:DC%2BD1cXosFGnsLY%3D 19808266
    • (2008) Circ Heart Fail , vol.1 , pp. 17-24
    • McMurray, J.J.1    Pitt, B.2    Latini, R.3
  • 75
    • 34848907212 scopus 로고    scopus 로고
    • Aliskiren, a novel renin inhibitor, is renoprotective in a model of advanced diabetic nephropathy in rats
    • DOI 10.1007/s00125-007-0795-9
    • DJ Kelly Y Zhang G Moe G Naik RE Gilbert 2007 Aliskiren, a novel renin inhibitor, is renoprotective in a model of advanced diabetic nephropathy in rats Diabetologia 50 2398 2404 10.1007/s00125-007-0795-9 1:CAS:528: DC%2BD2sXhtFSlsL%2FI 17828524 (Pubitemid 47512400)
    • (2007) Diabetologia , vol.50 , Issue.11 , pp. 2398-2404
    • Kelly, D.J.1    Zhang, Y.2    Moe, G.3    Naik, G.4    Gilbert, R.E.5
  • 76
    • 46449118638 scopus 로고    scopus 로고
    • Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats
    • 10.1161/HYPERTENSIONAHA.107.108845 1:CAS:528:DC%2BD1cXntVaisL0%3D 18490518
    • DL Feldman L Jin H Xuan, et al. 2008 Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats Hypertension 52 130 136 10.1161/HYPERTENSIONAHA.107.108845 1:CAS:528:DC%2BD1cXntVaisL0%3D 18490518
    • (2008) Hypertension , vol.52 , pp. 130-136
    • Feldman, D.L.1    Jin, L.2    Xuan, H.3
  • 79
    • 33947182655 scopus 로고    scopus 로고
    • Aliskiren, an Oral Renin Inhibitor, Provides Dose-Dependent Efficacy and Sustained 24-Hour Blood Pressure Control in Patients With Hypertension
    • DOI 10.1016/j.jacc.2006.11.032, PII S0735109706032037
    • BH Oh J Mitchell JR Herron, et al. 2007 Aliskiren, an oral renin inhibitor, provides dose-dependent efficacy and sustained 24-hour blood pressure control in patients with hypertension J Am Coll Cardiol 49 1157 1163 10.1016/j.jacc.2006.11.032 1:CAS:528:DC%2BD2sXjtVagurk%3D 17367658 (Pubitemid 46400330)
    • (2007) Journal of the American College of Cardiology , vol.49 , Issue.11 , pp. 1157-1163
    • Oh, B.-H.1    Mitchell, J.2    Herron, J.R.3    Chung, J.4    Khan, M.5    Keefe, D.L.6
  • 80
    • 39849089447 scopus 로고    scopus 로고
    • Comparative efficacy and safety of aliskiren, an oral direct renin inhibitor, and ramipril in hypertension: A 6-month, randomized, double-blind trial
    • DOI 10.1097/HJH.0b013e3282f3ad9a, PII 0000487220080300000030
    • K Andersen MH Weinberger B Egan, et al. 2008 Comparative efficacy and safety of aliskiren, an oral direct renin inhibitor, and ramipril in hypertension: a 6-month, randomized, double-blind trial J Hypertens 26 589 599 10.1097/HJH.0b013e3282f3ad9a 1:CAS:528:DC%2BD1cXisVWhur0%3D 18300872 (Pubitemid 351317270)
    • (2008) Journal of Hypertension , vol.26 , Issue.3 , pp. 589-592
    • Andersen, K.1    Weinberger, M.H.2    Egan, B.3    Constance, C.M.4    Ali, M.A.5    Jin, J.6    Keefe, D.L.7
  • 81
    • 0347479295 scopus 로고    scopus 로고
    • Blood Pressure Lowering in Essential Hypertension with an Oral Renin Inhibitor, Aliskiren
    • DOI 10.1161/01.HYP.0000101688.17370.87
    • A Stanton C Jensen J Nussberger E O'Brien 2003 Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren Hypertension 42 1137 1143 10.1161/01.HYP.0000101688.17370.87 1:CAS:528:DC%2BD3sXpsVGisrg%3D 14597641 (Pubitemid 37549068)
    • (2003) Hypertension , vol.42 , Issue.6 , pp. 1137-1143
    • Stanton, A.1    Jensen, C.2    Nussberger, J.3    O'Brien, E.4
  • 82
    • 44849114597 scopus 로고    scopus 로고
    • Aliskiren combined with losartan in type 2 diabetes and nephropathy
    • DOI 10.1056/NEJMoa0708379
    • HH Parving F Persson JB Lewis EJ Lewis NK Hollenberg 2008 Aliskiren combined with losartan in type 2 diabetes and nephropathy N Engl J Med 358 2433 2446 10.1056/NEJMoa0708379 1:CAS:528:DC%2BD1cXmvFKmtLY%3D 18525041 (Pubitemid 351793017)
    • (2008) New England Journal of Medicine , vol.358 , Issue.23 , pp. 2433-2446
    • Parving, H.-H.1    Persson, F.2    Lewis, J.B.3    Lewis, E.J.4    Hollenberg, N.K.5
  • 83
    • 65249182083 scopus 로고    scopus 로고
    • Aliskiren trial in type 2 diabetes using cardio-renal endpoints (ALTITUDE): Rationale and study design
    • 10.1093/ndt/gfn721 1:CAS:528:DC%2BD1MXkvFKjsLs%3D 19145003
    • HH Parving BM Brenner JJ McMurray, et al. 2009 Aliskiren trial in type 2 diabetes using cardio-renal endpoints (ALTITUDE): rationale and study design Nephrol Dial Transplant 24 1663 1671 10.1093/ndt/gfn721 1:CAS:528: DC%2BD1MXkvFKjsLs%3D 19145003
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 1663-1671
    • Parving, H.H.1    Brenner, B.M.2    McMurray, J.J.3
  • 84
    • 34447621764 scopus 로고    scopus 로고
    • Antihypertensive efficacy, safety, and tolerability of the oral direct renin inhibitor aliskiren in patients with hypertension: A pooled analysis
    • DOI 10.1016/j.jash.2007.04.004, PII S1933171107000897
    • MR Weir C Bush DR Anderson, et al. 2007 Antihypertensive efficacy, safety, and tolerability of the oral direct renin inhibitor aliskiren in patients with hypertension: a pooled analysis J Am Soc Hypertens 1 264 277 10.1016/j.jash.2007.04.004 20409858 (Pubitemid 47091546)
    • (2007) Journal of the American Society of Hypertension , vol.1 , Issue.4 , pp. 264-277
    • Weir, M.R.1    Bush, C.2    Anderson, D.R.3    Zhang, J.4    Keefe, D.5    Satlin, A.6
  • 85
    • 42549113198 scopus 로고    scopus 로고
    • Long-term safety, tolerability and efficacy of aliskiren in combination with valsartan in patients with hypertension: A 6-month interim analysis
    • DOI 10.1185/030079908X280581
    • SG Chrysant AV Murray UC Hoppe, et al. 2008 Long-term safety, tolerability and efficacy of aliskiren in combination with valsartan in patients with hypertension: a 6-month interim analysis Curr Med Res Opin 24 1039 1047 10.1185/030079908X280581 1:CAS:528:DC%2BD1cXmsVWgtbg%3D 18307835 (Pubitemid 351579161)
    • (2008) Current Medical Research and Opinion , vol.24 , Issue.4 , pp. 1039-1047
    • Chrysant, S.G.1    Murray, A.V.2    Hoppe, U.C.3    Dattani, D.4    Patel, S.5    Hsu, H.6    Zhang, J.7
  • 86
    • 3442888821 scopus 로고    scopus 로고
    • Managing hyperkalemia caused by inhibitors of the renin-angiotensin- aldosterone system
    • DOI 10.1056/NEJMra035279
    • BF Palmer 2004 Managing hyperkalemia caused by inhibitors of the renin-angiotensin-aldosterone system N Engl J Med 351 585 592 10.1056/NEJMra035279 1:CAS:528:DC%2BD2cXmtF2ru7o%3D 15295051 (Pubitemid 39025174)
    • (2004) New England Journal of Medicine , vol.351 , Issue.6
    • Palmer, B.F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.