Pre-clinical evaluation of a 213Bi-labeled 2556 antibody to HIV-1 gp41 glycoprotein in HIV-1 mouse models as a reagent for HIV eradication

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Dadachova, Ekaterina ^a   Kitchen, Scott G ^b   Bristol, Gregory ^b   Baldwin, Gayle Cocita ^b   Revskaya, Ekaterina ^a   Empig, Cyril ^c   Thornton, George B ^c   Gorny, Miroslaw K ^d   Zolla Pazner, Susan ^d,e   Casadevall, Arturo ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Pain Therapeutics Inc   (United States)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; BISMUTH MONOCLONAL ANTIBODY 2556 BI 213; GLYCOPROTEIN GP 41; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG; BISMUTH; GP41 PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; RADIOISOTOPE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL KILLING; CONTROLLED STUDY; DRUG EFFICACY; DRUG PROTEIN BINDING; DRUG SCREENING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IMMUNOREACTIVITY; IMMUNOTOXICITY; IN VIVO STUDY; ISOTOPE LABELING; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; THROMBOCYTE COUNT; TOXICITY TESTING; VIRUS PARTICLE; ANIMAL; CYTOLOGY; DISEASE CONTROL; EVALUATION; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY; METHODOLOGY; MONONUCLEAR CELL; PERITONEUM; SPLEEN; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1; MUS;

ANIMALS; ANTIBODIES, MONOCLONAL; BISMUTH; DISEASE ERADICATION; DRUG EVALUATION, PRECLINICAL; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP41; HIV INFECTIONS; HIV-1; LEUKOCYTES, MONONUCLEAR; MICE; PERITONEUM; PLATELET COUNT; RADIOISOTOPES; SPLEEN;

EID: 84857952424     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0031866     Document Type: Article

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