Indomethacin antagonizes EP2 prostanoid receptor activation in LS174T human colon cancer cells

European Journal of Pharmacology

Volumn 680, Issue 1-3, 2012, Pages 16-21

  Ikawa, Yuta ^a   Fujino, Hiromichi ^a   Otake, Sho ^a   Murayama, Toshihiko ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

Colon cancer; COX inhibition independent effect; EP2 prostanoid receptor; G protein coupled receptor; Indomethacin; NSAID

Indexed keywords

CYCLOOXYGENASE 2; INDOMETACIN; PROSTAGLANDIN E RECEPTOR 2; PROSTAGLANDIN E2;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; COLON CANCER; CONTROLLED STUDY; DRUG MECHANISM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ALPROSTADIL; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; COLONIC NEOPLASMS; CYCLIC AMP; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DINOPROSTONE; HUMANS; INDOMETHACIN; PROSTAGLANDINS; RECEPTORS, PROSTAGLANDIN E, EP2 SUBTYPE; SECRETIN;

EID: 84857923084     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.01.033     Document Type: Article

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