Genotype-phenotype correlation related to lipid profile in beta-thalassemia major and intermedia in southern Iran

Journal of Clinical Lipidology

Volumn 6, Issue 2, 2012, Pages 108-113

  Bordbar, Mohammadreza ^a   Haghpanah, Sezaneh ^a   Afrasiabi, Abdolreza ^a   Dehbozorgian, Javad ^a   Karimi, Mehran ^a  

^a SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

thalassemia intermedia; thalassemia major; Genotype; Lipid profiles

Indexed keywords

BETA GLOBIN; FERRITIN; HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; ARTICLE; BETA THALASSEMIA; CASE CONTROL STUDY; CHOLESTEROL BLOOD LEVEL; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FERRITIN BLOOD LEVEL; GENE MUTATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENOTYPE; HUMAN; IRAN; LIPID ANALYSIS; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; PROSPECTIVE STUDY; SPLENECTOMY; THALASSEMIA MAJOR;

ADOLESCENT; ADULT; BETA-THALASSEMIA; CASE-CONTROL STUDIES; CHILD; FEMALE; GENOTYPE; HUMANS; IRAN; LIPIDS; MALE; MUTATION; PHENOTYPE; YOUNG ADULT;

EID: 84857916122     PISSN: 19332874     EISSN: 18764789     Source Type: Journal    
DOI: 10.1016/j.jacl.2011.12.005     Document Type: Article

References (22)

1. S. Haghpanah, M. Davani, and B. Samadi Serum lipid profiles in patients with beta-thalassemia major and intermedia in southern Iran J Res Med Sci 15 2010 150 154
2. P. Ricchi, M. Ammirabile, and A. Spasiano Hypocholesterolemia in adult patients with thalassemia: a link with the severity of genotype in thalassemia intermedia patients Eur J Hematol 82 2009 219 222
3. H. Madani, Z. Rahimi, and M. Manavi-Shad Plasma lipids and lipoproteins in children and young adults with major beta-thalassemia from western Iran: influence of genotype Mol Biol Rep 38 2011 2573 2578
4. C. Chrysohoou, D.B. Panagiotokos, and C. Pitsavos Distribution of serum lipids and lipoproteins in patients with beta thalassemia major; an epidemiological study in young adults from Greece Lipids Health Dis 3 2004 3
5. C. Hartman, H. Tamary, and A. Tamir Hypocholesterolemia in children and adolescents with beta-thalassemia intermedia J Pediatr 141 2002 543 547 (Pubitemid 35193321)
6. K.M. Mansi, and T.A. Aburjai Lipid profile in Jordanian children with beta-thalassemia major Int J Hematol 18 2008 93 98 (Pubitemid 352007972)
7. F.A. Al-Quobaili, and I.E. Abou Asali Serum levels of lipids and lipoproteins in Syrian patients with beta-thalassemia major Saudi Med J 25 2004 871 875 (Pubitemid 39137144)
8. M.R. Nasr, A.M. Abdelmaskoud, and K.S. Abd El-Aal Plasma lipid profile and lipid peroxidation in beta-thalassemic children J Clin Lipidol 2 2008 405 409 (Pubitemid 352795720)
9. M. Maioli, G.B. Vigna, and G. Tonolo Plasma lipoprotein composition, apolipoprotein(a) concentration and isoforms in beta-thalassemia Atherosclerosis 131 1997 127 133 (Pubitemid 27240105)
10. D.A. Papanastasiou, T. Siorokou, and F.A. Haliotis Beta-thalassemia and factors affecting the metabolism of lipids and lipoproteins Hematologica (Budap) 27 1996 143 153 (Pubitemid 126504839)
11. J.R. Brewer New features of the National Cholesterol Education Program Adult Treatment Panel III lipid-lowering guidelines Clin Cardiol 26 4suppl 3 2003 19 24
12. P. Brizzi, G. Tonolo, and F. Carusillo Plasma lipid composition and LDL oxidation Clin Chem Lab Med 41 2003 56 60 (Pubitemid 36285386)
13. E. Fibach, and E.A. Rachmilevitz The role of antioxidants and iron chelators in the treatment of oxidative stress in thalassemia Ann NY Acad Sci 1202 2010 10 16
14. E. Fibach, E.S. Tan, and S. Jamuar Amelioration of oxidative stress in red blood cells from patients with beta-thalassemia major and intermedia and E-beta-thalassemia following administration of a fermented papaya preparation Phytother Res 24 2010 1334 1338
15. L.N. Grinberg, H. Newmark, and N. Kitrossky Protective effects of tea polyphenols against oxidative damage to red blood cells Biochem Pharmacol 54 1997 973 978 (Pubitemid 27475235)
16. C. Thephinlap, C. Phisalaphong, and S. Fucharoen Efficacy of curcuminoids in alleviation of iron overload and lipid peroxidation in thalassemic mice Med Chem 5 2009 472 482
17. P. Ricchi, M. Ammirabile, and A. Maggio Hypocholesterolemia in thalassemia pathogenesis, implications and clinical effects Eur Haematol 4 2010 20 23
18. H. Abolghasemi, A. Amid, and S. Zeinali Thalassemia in Iran: epidemiology, prevention, and management J Pediatr Hematol Oncol 29 2007 233 238 (Pubitemid 46597687)
19. H. Najmabadi, R. Karimi-Nejad, and S. Sahebjam The beta-thalassemia mutation spectrum in the Iranian population Hemoglobin 25 2001 285 296 (Pubitemid 32845932)
20. M. Karimi, H. Yarmohammadi, and S. Farjadian Beta-thalassemia intermedia from southern Iran: IVS II-1 (G>A) is the prevalent thalassemia intermedia allele Hemoglobin 26 2002 147 154 (Pubitemid 34779263)
21. H. Shalev, J. Kapelushnik, and A. Moser Hypocholesterolemia in chronic anemias with increased erythropoietic activity Am J Hematol 82 2007 199 202 (Pubitemid 46363785)
22. B. Atac, D. Brahaj, W.H. Frishman, and R. Lerner Anemia and hypocholesterolemia Heart Dis 5 2003 65 71 (Pubitemid 36184129)