Biochemical, mutational and in silico structural evidence for a functional dimeric form of the ornithine decarboxylase from entamoeba histolytica

PLoS Neglected Tropical Diseases

Volumn 6, Issue 2, 2012, Pages

  Preeti, ^a   Tapas, Satya ^a   Kumar, Pravindra ^a   Madhubala, Rentala ^b   Tomar, Shailly ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY ROORKEE   (India)

^b JAWAHARLAL NEHRU UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CYSTEINE; GLUTARALDEHYDE; GLYCINE; LYSINE; ORNITHINE DECARBOXYLASE; RECOMBINANT PROTEIN; TYROSINE; MUTANT PROTEIN;

AMEBIASIS; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; DIMERIZATION; DRUG TARGETING; ENTAMOEBA HISTOLYTICA; ENZYME ACTIVE SITE; ENZYME ASSAY; ESCHERICHIA COLI; GEL PERMEATION CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; AMINO ACID SUBSTITUTION; CHEMISTRY; ENZYME STABILITY; ENZYMOLOGY; GEL CHROMATOGRAPHY; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN STABILITY;

AMINO ACID SUBSTITUTION; CATALYTIC DOMAIN; CHROMATOGRAPHY, GEL; CIRCULAR DICHROISM; ENTAMOEBA HISTOLYTICA; ENZYME STABILITY; ESCHERICHIA COLI; MASS SPECTROMETRY; MOLECULAR DYNAMICS SIMULATION; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; ORNITHINE DECARBOXYLASE; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; RECOMBINANT PROTEINS;

EID: 84857857860     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0001559     Document Type: Article

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