Influenza virus: A single noninfectious interferon induction-suppressing particle blocks expression of interferon-inducing particles

Journal of Interferon and Cytokine Research

Volumn 32, Issue 3, 2012, Pages 121-126

  Malinoski, Christopher P ^a   Marcus, Philip I ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INFLUENZA VACCINE; INTERFERON INDUCING AGENT;

ANIMAL CELL; ARTICLE; EMBRYO; INFLUENZA VIRUS; INTERFERON INDUCTION; INTERFERON PRODUCTION; NONHUMAN; PRIORITY JOURNAL; VIRUS PARTICLE;

ANIMALS; CELLS, CULTURED; CHICK EMBRYO; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; INFLUENZA VACCINES; INTERFERON INDUCERS; INTERFERONS; ORTHOMYXOVIRIDAE; VACCINES, ATTENUATED; VIRION;

INFLUENZAVIRUS A; ORTHOMYXOVIRIDAE;

EID: 84857857264     PISSN: 10799907     EISSN: 15577465     Source Type: Journal    
DOI: 10.1089/jir.2011.0078     Document Type: Article

References (32)

1. Bellett AJD, Cooper PD. 1959. Some properties of the transmissible interfering component of vesicular stomatitis virus preparations. J Gen Microbiol 21:498-509.
2. Bracci L, Canini I, Puzelli S, Sestili P, Venditti M, Spada M, Donatelli I, Belardelli F, Proietti E. 2005. Type I IFN is a powerful mucosal adjuvant for a selective intranasal vaccination against influenza virus in mice and affects antigen capture at mucosal level. Vaccine 23:2994-3004.
3. Bracci L, Canini I, Venditti M, Spada M, Puzelli S, Donatelli I, Belardelli F, Proietti E. 2006. Type I IFN as a vaccine adjuvant for both systemic and mucosal vaccination against influenza virus. Vaccine 24:S56-S57.
4. Carver DH, Marcus PI. 1967. Enhanced interferon production from chick embryo cells aged in in vitro. Virology 32:247-257.
5. Cauthen AN, Swayne DE, Sekellick MJ, Marcus PI, Suarez DL. 2007. Amelioration of influenza virus pathogenesis in chickens attributed to the enhanced interferon-inducing capacity of a virus with a truncated NS1 gene. J Virol 81:1838-1847.
6. Desselberger U. 1975. Relation of virus particle counts to the hemagglutinating activity of influenza virus suspensions measured by the HA pattern test and by use of the photometric HCU method. Arch Virol 49:365-372.
7. Donald HB, Isaacs A. 1954. Counts of influenza virus particles. J Gen Microbiol 10:457-464.
8. Hai R, Martínez-Sobrido L, Fraser KA, Ayllon J, García-Sastre A, Palese P. 2008. Influenza B virus NS1-truncated mutants: Liveattenuated vaccine approach. J Virol 82:10580-10590.
9. Kochs G, Martínez-Sobrido L, Lienenklaus S, Weiss S, García-Sastre A, Staeheli P. 2009. Strong interferon-inducing capacity of a highly virulent variant of influenza A virus strain PR8 with deletions in the NS1 gene. J Gen Virol 90:2990-2994.
10. Marcus PI. 1959. Host-cell interaction of animal viruses. II. Cellkilling particle enumeration: Survival curves at low multiplicities. Virology 9:546-563.
11. Marcus PI. 1982. Interferon induction by viruses. IX. Antagonistic activities of virus particles modulated interferon production. J Interferon Res 2:511-518.
12. Marcus PI. 1986. Interferon induction: Dose-response curves. Meth Enzymol 119:106-114.
13. Marcus PI, Girshick T, van der Heide L, Sekellick MJ. 2007. Super-sentinel chickens and detection of low-pathogenicity influenza virus. Emerging Infect Dis 13:1608-1610.
14. Marcus PI, Ngunjiri JM, Sekellick MJ. 2009. Dynamics of biologically active subpopulations of influenza virus: Plaqueforming, noninfectious cell-killing, and defective interfering particles. J Virol 83:8122-8130.
15. Marcus PI, Ngunjiri JM, Sekellick MJ, Wang L, Lee C-W. 2010. In vitro analysis of virus particle subpopulations in candidate live-attenuated influenza vaccines distinguishes effective from ineffective vaccines. J Virol 84:10974-10981.
16. Marcus PI, Rojek JM, Sekellick MJ. 2005. Interferon induction and/or production and its suppression by influenza A viruses. J Virol 79:2880-2890.
17. Marcus PI, Sekellick MJ. 1977. Defective interfering particles with covalently linked [ + /-] RNA induce interferon. Nature 266:815-819.
18. Marcus PI, Sekellick MJ. 1985. Interferon induction by viruses. XIII. Detection and assay of interferon induction-suppressing particles. Virology 142:411-415.
19. Nagao Y, Yamashiro K, Hara N, Horisawa Y, Kato K, Uemura A. 1998. Oral-mucosal administration of IFN-a potentiates immune response in mice. J Interferon Cytokine Res 18:661-666.
20. Nayak DP, Chambers TM, Akkina RK. 1985. Defective-interfering (DI) RNAs of influenza viruses: Origin, structure, expression, and interference. Curr Top Microbiol Immunol 114: 103-151.
21. Ngunjiri JM, Sekellick MJ, Marcus PI. 2008. Clonogenic assay of type A influenza viruses reveals noninfectious cell-killing (apoptosis-inducing) particles. J Virol 82:2673-2680.
22. Palese P, Shaw ML. 2007. Orthomyxoviruses: The viruses and their replication. In: Knipe DM, Howley PM, eds. Fields virology, 5th ed. Philidelphia, PA: Lippincott Williams & Wilkins, pp 1647-1689.
23. Richt JA, García-Sastre A. 2009. Attenuated influenza virus vaccines with modified NS1 proteins. Curr Top Microbiol Immunol 333:177-195.
24. Salomon R, Webster RG. 2009. The influenza virus enigma. Cell 136:402-410.
25. Sekellick MJ, Carra SA, Bowman A, Hopkins DA, Marcus PI. 2000. Transient resistance of influenza virus to interferon action attributed to random multiple packaging and activity of NS genes. J Interferon Cytokine Res 20:963-970.
26. Sekellick MJ, Marcus PI. 1986. Induction of high titer chicken interferon. Methods Enzymol 119:115-125.
27. Steel J, Lowen AC, Pena L, Angel M, Solórzano A, Albrecht R, Perez DR, García-Sastre A, Palese P. 2009. Live attenuated influenza viruses containing NS1 truncations as vaccine candidates against H5N1 highly pathogenic avian influenza. J Virol 83:1742-1753.
28. Tough DF, Borrow P, Sprent J. 1996. Induction of bystander T cell proliferation by viruses and type I interferon in vivo. Science 272:1947-1950.
29. Von Magnus P. 1954. Incomplete forms of influenza virus. Adv Virus Res 2:59-79.
30. Wang L, Suarez DL, Pantin-Jackwood M, Mibayashi M, García-Sastre A, Saif YM, Lee C-W. 2008. Characterization of influenza virus variants with different sizes of the non-structural (NS) genes and their potential as a live influenza vaccine in poultry. Vaccine 26:3580-3586.
31. Winship TR, Marcus PI. 1980. Interferon induction by viruses. VI. Reovirus; virus genome dsRNA as the interferon inducer in aged chick embryo cells. J Interferon Res 1:155-167.
32. Wolff T, Ludwig S. 2009. Influenza viruses control the vertebrate type I interferon system: Factors, mechanisms, and consequences. J Interferon Cytokine Res 29:549-557.