Quantitative protease cleavage site profiling using tandem-mass-tag labeling and LC-MALDI-TOF/TOF MS/MS analysis

Journal of Proteome Research

Volumn 11, Issue 3, 2012, Pages 1812-1820

  Jakoby, Thomas ^a   Van Den Berg, Bart H J ^a   Tholey, Andreas ^a  

^a UNIVERSITY OF KIEL   (Germany)

Author keywords

isobaric labeling; mass spectrometry; peptide library; PICS approach; relative quantification; TMT

Indexed keywords

ENDOPROTEINASE GLUC; METALLOPROTEINASE; PROTEINASE; UNCLASSIFIED DRUG;

CHEMICAL BOND; CONFERENCE PAPER; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PEPTIDE LIBRARY; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEOMICS; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS;

AMINO ACID SEQUENCE; BINDING SITES; BUFFERS; CHROMATOGRAPHY, LIQUID; ENDOPEPTIDASES; ENZYME ASSAYS; PEPTIDE FRAGMENTS; PEPTIDE MAPPING; PROTEOLYSIS; PROTEOME; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ANALYSIS, PROTEIN; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; STAINING AND LABELING; SUBSTRATE SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 84857825369     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr201051e     Document Type: Conference Paper

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