Aberrant chondrocyte hypertrophy and activation of ß-catenin signaling precede joint ankylosis in ank/ank mice

Journal of Rheumatology

Volumn 39, Issue 3, 2012, Pages 583-593

  Las Heras, Facundo ^a,b   Pritzker, Kenneth P H ^a,b   So, Anthony ^b   Tsui, Hing Wo ^c   Chiu, Basil ^c   Inman, Robert D ^c   Tsui, Florence W L ^c  

^a Pediatric Oral and Maxillofacial Surgery   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Catenin signaling; Ank mouse; Ankylosing spondylitis; Chondrocyte hypertrophy; Osteoarthritis

Indexed keywords

ALKALINE PHOSPHATASE; BETA CATENIN; CELL PROTEIN; COLLAGEN TYPE 10; PROTEIN ANTIBODY; PROTEIN AXIN2; TISSUE NONSPECIFIC ALKALINE PHOSPHATASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANK GENE; ANKYLOSIS; ARTICLE; ARTICULAR CARTILAGE; CALCIFICATION; CARTILAGE; CARTILAGE THICKNESS; CELL MATURATION; CELL NUCLEUS; CELL SIZE; CHONDROCYTE HYPERTROPHY; CHONDROPATHY; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE; GENE FUNCTION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MORPHOMETRICS; MOUSE; MOUSE MUTANT; MOUSE STRAIN; NONHUMAN; PATHOGENESIS; PERINATAL PERIOD; PHENOTYPE; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; WILD TYPE;

ALKALINE PHOSPHATASE; ANIMALS; ANKYLOSIS; AXIN PROTEIN; BETA CATENIN; CARTILAGE, ARTICULAR; CHONDROCYTES; COLLAGEN TYPE X; FEMALE; HETEROZYGOTE; HYPERTROPHY; JOINTS; MICE; MICE, MUTANT STRAINS; MODELS, ANIMAL; PHENOTYPE; SIGNAL TRANSDUCTION;

EID: 84857820408     PISSN: 0315162X     EISSN: 14992752     Source Type: Journal    
DOI: 10.3899/jrheum.110971     Document Type: Article

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