Carbohydrate-associated immunodominant epitope(s) of CA215

Immunological Investigations

Volumn 41, Issue 3, 2012, Pages 317-336

  Lee, Gregory ^a   Zhu, Mingang ^a   Ge, Bixia ^a   Cheung, Anthony P ^a   Chien, Chien Hsiang ^b   Chow, Song Nan ^c   Ding, Yi Peng ^d   Yao, Hong Xia ^d  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^d HAINAN PROVINCIAL PEOPLE S HOSPITAL   (China)

Author keywords

Carbohydrate associated epitopes; Immunoglobulin superfamily proteins; Monoclonal antibody; RCA; RP215

Indexed keywords

CARBOHYDRATE; CARBOHYDRATE EPITOPE CA215; EPITOPE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY RCA10; MONOCLONAL ANTIBODY RCA100; MONOCLONAL ANTIBODY RCA104; MONOCLONAL ANTIBODY RCA110; MONOCLONAL ANTIBODY RCA111; MONOCLONAL ANTIBODY RP215; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN RECOGNITION; ARTICLE; CANCER CELL CULTURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY-DEPENDENT CELL CYTOTOXICITY; ANTIGENS, NEOPLASM; CELL LINE, TUMOR; FEMALE; IMMUNODOMINANT EPITOPES; IMMUNOTHERAPY; MICE; MICE, INBRED BALB C; OVARIAN NEOPLASMS; PROTEIN CONFORMATION;

EID: 84857809795     PISSN: 08820139     EISSN: 15324311     Source Type: Journal    
DOI: 10.3109/08820139.2011.633141     Document Type: Article

References (26)

1. Caccamo, N., Barera, A., Di Sano, C., Meraviglia, S., Ivanyi, J., Hudecz, F., Bosze, S., Dieli, F., Salerno, A. (2003). Cytokine profile, HLA restriction and TCR sequence analysis of human CD4+ T clones specific for an immunodominant epitope of Mycobaterium tuberculosis 16-KDa protein. Clin. Exp. Immunol. 133:260-266. (Pubitemid 36918601)
2. Filman, D. J., Brawn, R. J., Dandliker, W. B. (1975). Intracellular supravital stain delocalization as an assay for antibody-dependent complement-mediated cell damage. J. Immunol. Meth. 6:189-207.
3. Griffioen, M., van Egmond, E. H., Kester, M. G., Willemze, R., Falkenburg, J. H., Heemskerk, M. H. (2009). Retroviral transfer of human CD20 as a suicide gene for adoptive T-cell therapy. Haematologica 94:1316-1320.
4. Hsu, S. M., Raine, L., Fanger, H. (1981). Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J. Histochem. Cytochem. 29:577-580. (Pubitemid 11147380)
5. Lee, G. (1997). Monoclonal antibodies against an antigen associated with ovarian cervical and other tumors. United States Patent number 5650291.
6. Lee, G. (2008). Carbohydrate-containing pan cancer marker. United States Patent Application No. 12/599284.
7. Lee, G. (2009) Cancer cell-expressed immunoglobulins: CA215 as a pan cancer marker and its diagnostic applications. Cancer Biomark 5:137-142.
8. Lee, G. (2010a). Carbohydrate hapten anticancer vaccines. United States Provisional Patent Application, Reference No. 61634-30003.00.
9. Lee, G. (2010b). Monoclonal antibodies against gonadotropin-releasing hormone receptor. U.S. Patent Application No. 61/239,704.
10. Lee, G., Azadi, P. (2011). Peptide mapping and glycoanalysis of cancer cell-expressed glycoproteins, CA215, recognized by RP215 monoclonal antibody. J. Carbohyd. Chem., in press.
11. Lee, G., Chen, K. W., Sheu, F. S., Tsang, A., Chao, K. C., Ng, H. T. (1992). Studies of a tumor-associated antigen, COX-1, recognized by a monoclonal antibody. Cancer Immunol. Immunother. 35:19-26.
12. Lee, G., Cheung, A. P., Ge, B., Zhu, M., Li, P., Hsu, E., Huang, T. K. (2010). Monoclonal anti-idiotype antibodies against carbohydrate-associated epitope for anti-cancer vaccine development. J. Vaccines Vaccin. 1:106. doi:10.4172/2157-7560.1000106.
13. Lee, G., Chu, R. A., Ting, H. H. (2009). Preclinical assessment of anti-cancer drugs by using RP215 monoclonal antibody. Cancer Biol. Ther. 8:161-162.
14. Lee, G., Ge, B. (2009). Cancer cell expressions of immunoglobulin heavy chains with unique carbohydrate-associated biomarker. Cancer Biomark 5:177-188.
15. Lee, G., Ge, B. (2010a). Inhibition of in vitro tumor cell growth by RP215 monoclonal antibody and antibodies raised against its anti-idiotype antibodies. Cancer Immunol. Immunother. 59:1347-1356.
16. Lee, G., Ge, B. (2010b). Growth inhibition of tumor cells in vitro by using monoclonal antibodies against gonadotropin-releasing hormone receptor. Cancer Immunol. Immunother. 59:1011-1019.
17. Lee, G., Ge, B., Huang, T. K., Zheng, G., Duan, J., Wang, I. H. (2010). Positive identification of CA215 pan cancer biomarker from serum specimens of cancer patients. Cancer Biomark 6:111-117.
18. Lee, G., Laflamme, E., Chien, C. H., Ting, H. H. (2008). Molecular identity of a pan cancer marker, CA215. Cancer Biol. Ther. 7:2007-2014.
19. Lee, G., Wu, Q., Li, C. H., Ting, H. H., Chien, C. H. (2006). Recent studies of a new carbohydrate-associated pan cancer marker, CA215. J. Clin. Ligand Assay 29:47-51. (Pubitemid 44701047)
20. Lee, G., Zhu, M., Ge, B., Potzold, S. (2011). Widespread expression of immunoglobulin superfamily proteins in cancer cells. Cancer Immunol. Immunother., in press (published online first on August 2011).
21. Liu, M. S., Aebersold, R., Fann, C. H., Lee, C. Y. (1992). Molecular and developmental studies of a sperm acrosome antigen recognized by HS-63 monoclonal antibody. Biol. Reprod. 46:937-948.
22. Macdonald, I. K., Harkiolaki, M., Hunt, L., Connelley, T., Carroll, A. V., MacHugh, N. D., Graham, S. P., Jones, E. Y., Morrison, W. I., Flower, D. R., Ellis, S. A. (2010). MHC Class I bound to an immunodominant theileria parva epitope demonstrates unconventional presentation to T cell receptors. PLoS Pathog. 6:1-11, e1001149.
23. Tenzer, S., Wee, E., Burgevin, A., Stewart-Jones, G., Friis, L., Lamberth, K., Chang, C., Harndahl, M., Weimershaus, M., Gerstoft, J., Akkad, N., Klenerman, P., Fugger, L., Jones, E. Y., McMichael, A. J., Buus, S., Schild, H., van Endert, P., Inversen, A. K. N. (2009). Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance. Nat. Immun. 10:636-647.
24. Van Heyningen, V., Brock, D. J., Van Heyningen, S. (1983). A simple method for ranking the affinities of monoclonal antibodies. J. Immunol. Meth. 62:147-153. (Pubitemid 13044724)
25. Wilson, E. H., Hunter, C. A. (2008). Immunodominance and recognition of intracellular pathogens. J. Infect. Dis. 198:1579-1581.
26. Zhao, X., Singh, S., Pardoux, C., Zhao, J., Hsi, E. D., Abo, A., Korver, W. (2010). Targeting C-type lectin-like molecule-1 for antibody-mediated immunotherapy in acute myeloid leukemia. Haematologica 95:71-78.