MRNA for N-Bak, a neuron-specific BH3-only splice isoform of Bak, escapes nonsense-mediated decay and is translationally repressed in the neurons

Cell Death and Disease

Volumn 3, Issue 2, 2012, Pages

  Jakobson, M ^a   Lintulahti, A ^a,b   Arumae U ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Alternative splicing; Cortical neurons; mRNA; N Bak; Nonsense mediated decay

Indexed keywords

CYCLOHEXIMIDE; MESSENGER RNA; PROTEASOME INHIBITOR; PROTEIN BAK; PROTEIN N BAK; UNCLASSIFIED DRUG; ISOPROTEIN; PROTEIN SYNTHESIS INHIBITOR;

5' UNTRANSLATED REGION; ALTERNATIVE RNA SPLICING; ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; EMBRYO; MITOCHONDRION; MOUSE; NONHUMAN; NONSENSE MEDIATED MRNA DECAY; PREMATURE TERMINATION CODON; PRIORITY JOURNAL; STOP CODON; TRANSLATION REGULATION; ANIMAL; ANIMAL EMBRYO; BIOSYNTHESIS; CYTOLOGY; DNA FLANKING REGION; DRUG EFFECT; EXON; GENETIC TRANSFECTION; GENETICS; HELA CELL; HUMAN; METABOLISM; NERVE CELL; PRIMARY CELL CULTURE; PROTEIN SYNTHESIS;

5' FLANKING REGION; ALTERNATIVE SPLICING; ANIMALS; APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; CODON, NONSENSE; CYCLOHEXIMIDE; EMBRYO, MAMMALIAN; EXONS; HELA CELLS; HUMANS; MICE; MITOCHONDRIA; NEURONS; PRIMARY CELL CULTURE; PROTEIN BIOSYNTHESIS; PROTEIN ISOFORMS; PROTEIN SYNTHESIS INHIBITORS; RNA, MESSENGER; TRANSFECTION;

EID: 84857806192     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2012.4     Document Type: Article

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