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Volumn 22, Issue 2, 2012, Pages 162-165

Role of EBER and BARF1 in nasopharyngeal carcinoma (NPC) tumorigenesis

Author keywords

BARF1; EBER; Epstein Barr virus; Exosome; Innate immunity; Nasopharyngeal carcinoma; Non coding RNA

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TOLL LIKE RECEPTOR 3;

EID: 84857793666     PISSN: 1044579X     EISSN: 10963650     Source Type: Journal    
DOI: 10.1016/j.semcancer.2011.12.007     Document Type: Review
Times cited : (67)

References (46)
  • 1
    • 34249064632 scopus 로고    scopus 로고
    • Epstein-Barr virus
    • Wolters Kluwer, Philadelphia, PA, D.M. Knipe, P.M. Howley (Eds.)
    • Rickinson A.B., Kieff E. Epstein-Barr virus. Fields virology 2002, 2655-2700. Wolters Kluwer, Philadelphia, PA. D.M. Knipe, P.M. Howley (Eds.).
    • (2002) Fields virology , pp. 2655-2700
    • Rickinson, A.B.1    Kieff, E.2
  • 2
    • 0023940404 scopus 로고
    • Altered expression of two Epstein-Barr virus early genes localized in BamHI-A in nonproducer Raji cells
    • Zhang C.X., Decaussin G., Daillie J., Ooka T. Altered expression of two Epstein-Barr virus early genes localized in BamHI-A in nonproducer Raji cells. J Virol 1988, 62:1862-1869.
    • (1988) J Virol , vol.62 , pp. 1862-1869
    • Zhang, C.X.1    Decaussin, G.2    Daillie, J.3    Ooka, T.4
  • 3
    • 0034306978 scopus 로고    scopus 로고
    • Expression of BARF1 gene encoded by Epstein-Barr virus in nasopharyngeal carcinoma biopsies
    • Decaussin G., Sbih-Lammali F., De Turenne-Tessier M., Bouguermouh A., Ooka T. Expression of BARF1 gene encoded by Epstein-Barr virus in nasopharyngeal carcinoma biopsies. Cancer Res 2000, 60:5584-5588.
    • (2000) Cancer Res , vol.60 , pp. 5584-5588
    • Decaussin, G.1    Sbih-Lammali, F.2    De Turenne-Tessier, M.3    Bouguermouh, A.4    Ooka, T.5
  • 4
    • 15944408797 scopus 로고    scopus 로고
    • Epstein-Barr virus (EBV)-encoded BARF1 gene is expressed in nasopharyngeal carcinoma and EBV-associated gastric carcinoma tissues in the absence of lytic gene expression
    • Seto E., Yang L., Middeldorp J., Sheen T.S., Chen J.Y., Fukayama M., et al. Epstein-Barr virus (EBV)-encoded BARF1 gene is expressed in nasopharyngeal carcinoma and EBV-associated gastric carcinoma tissues in the absence of lytic gene expression. J Med Virol 2005, 76:82-88.
    • (2005) J Med Virol , vol.76 , pp. 82-88
    • Seto, E.1    Yang, L.2    Middeldorp, J.3    Sheen, T.S.4    Chen, J.Y.5    Fukayama, M.6
  • 5
    • 0035200854 scopus 로고    scopus 로고
    • The role of EBERs in oncogenesis
    • Takada K., Nanbo A. The role of EBERs in oncogenesis. Semin Cancer Biol 2001, 11:461-467.
    • (2001) Semin Cancer Biol , vol.11 , pp. 461-467
    • Takada, K.1    Nanbo, A.2
  • 6
    • 0026452862 scopus 로고
    • Localization of Epstein-Barr virus-encoded RNAs EBER-1 and EBER-2 in interphase and mitotic Burkitt lymphoma cells
    • Schwemmle M., Clemens M.J., Hilse K., Pfeifer K., Troster H., Muller W.E., et al. Localization of Epstein-Barr virus-encoded RNAs EBER-1 and EBER-2 in interphase and mitotic Burkitt lymphoma cells. Proc Natl Acad Sci USA 1992, 89:10292-10296.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10292-10296
    • Schwemmle, M.1    Clemens, M.J.2    Hilse, K.3    Pfeifer, K.4    Troster, H.5    Muller, W.E.6
  • 7
    • 0019444924 scopus 로고
    • Two small RNAs encoded by Epstein-Barr virus and complexed with protein are precipitated by antibodies from patients with systemic lupus erythematosus
    • Lerner M.R., Andrews N.C., Miller G., Steitz J.A. Two small RNAs encoded by Epstein-Barr virus and complexed with protein are precipitated by antibodies from patients with systemic lupus erythematosus. Proc Natl Acad Sci USA 1981, 78:805-809.
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 805-809
    • Lerner, M.R.1    Andrews, N.C.2    Miller, G.3    Steitz, J.A.4
  • 8
    • 0026021681 scopus 로고
    • EAP, a highly conserved cellular protein associated with Epstein-Barr virus small RNAs (EBERs)
    • Toczyski D.P., Steitz J.A. EAP, a highly conserved cellular protein associated with Epstein-Barr virus small RNAs (EBERs). EMBO J 1991, 10:459-466.
    • (1991) EMBO J , vol.10 , pp. 459-466
    • Toczyski, D.P.1    Steitz, J.A.2
  • 9
    • 0023711208 scopus 로고
    • Isolation and characterization of the genes for two small RNAs of herpesvirus papio and their comparison with Epstein-Barr virus-encoded EBER RNAs
    • Howe J.G., Shu M.D. Isolation and characterization of the genes for two small RNAs of herpesvirus papio and their comparison with Epstein-Barr virus-encoded EBER RNAs. J Virol 1988, 62:2790-2798.
    • (1988) J Virol , vol.62 , pp. 2790-2798
    • Howe, J.G.1    Shu, M.D.2
  • 10
    • 0025971705 scopus 로고
    • Binding of Epstein-Barr virus small RNA EBER-1 to the double-stranded RNA-activated protein kinase DAI
    • Clarke P.A., Schwemmle M., Schickinger J., Hilse K., Clemens M.J. Binding of Epstein-Barr virus small RNA EBER-1 to the double-stranded RNA-activated protein kinase DAI. Nucleic Acids Res 1991, 19:243-248.
    • (1991) Nucleic Acids Res , vol.19 , pp. 243-248
    • Clarke, P.A.1    Schwemmle, M.2    Schickinger, J.3    Hilse, K.4    Clemens, M.J.5
  • 11
    • 0025298202 scopus 로고
    • Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon
    • Meurs E., Chong K., Galabru J., Thomas N.S., Kerr I.M., Williams B.R., et al. Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon. Cell 1990, 62:379-390.
    • (1990) Cell , vol.62 , pp. 379-390
    • Meurs, E.1    Chong, K.2    Galabru, J.3    Thomas, N.S.4    Kerr, I.M.5    Williams, B.R.6
  • 12
    • 0027487288 scopus 로고
    • Comparative analysis of the regulation of the interferon-inducible protein kinase PKR by Epstein-Barr virus RNAs EBER-1 and EBER-2 and adenovirus VAI RNA
    • Sharp T.V., Schwemmle M., Jeffrey I., Laing K., Mellor H., Proud C.G., et al. Comparative analysis of the regulation of the interferon-inducible protein kinase PKR by Epstein-Barr virus RNAs EBER-1 and EBER-2 and adenovirus VAI RNA. Nucleic Acids Res 1993, 21:4483-4490.
    • (1993) Nucleic Acids Res , vol.21 , pp. 4483-4490
    • Sharp, T.V.1    Schwemmle, M.2    Jeffrey, I.3    Laing, K.4    Mellor, H.5    Proud, C.G.6
  • 13
    • 33748944149 scopus 로고    scopus 로고
    • EB virus-encoded RNAs are recognized by RIG-I and activate signaling to induce type I IFN
    • Samanta M., Iwakiri D., Kanda T., Imaizumi T., Takada K. EB virus-encoded RNAs are recognized by RIG-I and activate signaling to induce type I IFN. EMBO J 2006, 25:4207-4214.
    • (2006) EMBO J , vol.25 , pp. 4207-4214
    • Samanta, M.1    Iwakiri, D.2    Kanda, T.3    Imaizumi, T.4    Takada, K.5
  • 14
    • 0030921087 scopus 로고    scopus 로고
    • Epstein-Barr virus infection of human gastric carcinoma cells: implication of the existence of a new virus receptor different from CD21
    • Yoshiyama H., Imai S., Shimizu N., Takada K. Epstein-Barr virus infection of human gastric carcinoma cells: implication of the existence of a new virus receptor different from CD21. J Virol 1997, 71:5688-5691.
    • (1997) J Virol , vol.71 , pp. 5688-5691
    • Yoshiyama, H.1    Imai, S.2    Shimizu, N.3    Takada, K.4
  • 15
    • 0031957568 scopus 로고    scopus 로고
    • Cell-to-cell contact as an efficient mode of Epstein-Barr virus infection of diverse human epithelial cells
    • Imai S., Nishikawa J., Takada K. Cell-to-cell contact as an efficient mode of Epstein-Barr virus infection of diverse human epithelial cells. J Virol 1998, 72:4371-4378.
    • (1998) J Virol , vol.72 , pp. 4371-4378
    • Imai, S.1    Nishikawa, J.2    Takada, K.3
  • 16
    • 14944353441 scopus 로고    scopus 로고
    • Epstein-Barr virus-encoded small RNA induces insulin-like growth factor 1 and supports growth of nasopharyngeal carcinoma-derived cell lines
    • Iwakiri D., Sheen T.S., Chen J.Y., Huang D.P., Takada K. Epstein-Barr virus-encoded small RNA induces insulin-like growth factor 1 and supports growth of nasopharyngeal carcinoma-derived cell lines. Oncogene 2005, 24:1767-1773.
    • (2005) Oncogene , vol.24 , pp. 1767-1773
    • Iwakiri, D.1    Sheen, T.S.2    Chen, J.Y.3    Huang, D.P.4    Takada, K.5
  • 17
    • 77956601893 scopus 로고    scopus 로고
    • Epstein-Barr virus infection in immortalized nasopharyngeal epithelial cells: regulation of infection and phenotypic characterization
    • Tsang C.M., Zhang G., Seto E., Takada K., Deng W., Yip Y.L., et al. Epstein-Barr virus infection in immortalized nasopharyngeal epithelial cells: regulation of infection and phenotypic characterization. Int J Cancer 2010, 127:1570-1583.
    • (2010) Int J Cancer , vol.127 , pp. 1570-1583
    • Tsang, C.M.1    Zhang, G.2    Seto, E.3    Takada, K.4    Deng, W.5    Yip, Y.L.6
  • 18
    • 47049129929 scopus 로고    scopus 로고
    • Epstein-Barr virus-encoded small RNA induces IL-10 through RIG-I-mediated IRF-3 signaling
    • Samanta M., Iwakiri D., Takada K. Epstein-Barr virus-encoded small RNA induces IL-10 through RIG-I-mediated IRF-3 signaling. Oncogene 2008, 27:4150-4160.
    • (2008) Oncogene , vol.27 , pp. 4150-4160
    • Samanta, M.1    Iwakiri, D.2    Takada, K.3
  • 20
    • 3242813113 scopus 로고    scopus 로고
    • The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
    • Yoneyama M., Kikuchi M., Natsukawa T., Shinobu N., Imaizumi T., Miyagishi M., et al. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol 2004, 5:730-737.
    • (2004) Nat Immunol , vol.5 , pp. 730-737
    • Yoneyama, M.1    Kikuchi, M.2    Natsukawa, T.3    Shinobu, N.4    Imaizumi, T.5    Miyagishi, M.6
  • 22
    • 80053086791 scopus 로고    scopus 로고
    • Retinoic acid inducible gene-I, more than a virus sensor
    • Liu F., Gu J. Retinoic acid inducible gene-I, more than a virus sensor. Protein Cell 2011, 2:351-357.
    • (2011) Protein Cell , vol.2 , pp. 351-357
    • Liu, F.1    Gu, J.2
  • 23
    • 79956300649 scopus 로고    scopus 로고
    • Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
    • Kawai T., Akira S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 2011, 34:637-650.
    • (2011) Immunity , vol.34 , pp. 637-650
    • Kawai, T.1    Akira, S.2
  • 24
    • 70350488070 scopus 로고    scopus 로고
    • Epstein-Barr virus (EBV)-encoded small RNA is released from EBV-infected cells and activates signaling from Toll-like receptor 3
    • Iwakiri D., Zhou L., Samanta M., Matsumoto M., Ebihara T., Seya T., et al. Epstein-Barr virus (EBV)-encoded small RNA is released from EBV-infected cells and activates signaling from Toll-like receptor 3. J Exp Med 2009, 206:2091-2099.
    • (2009) J Exp Med , vol.206 , pp. 2091-2099
    • Iwakiri, D.1    Zhou, L.2    Samanta, M.3    Matsumoto, M.4    Ebihara, T.5    Seya, T.6
  • 26
    • 0034602538 scopus 로고    scopus 로고
    • Malignant transformation of B lymphoma cell line BJAB by Epstein-Barr virus-encoded small RNAs
    • Yamamoto N., Takizawa T., Iwanaga Y., Shimizu N., Yamamoto N. Malignant transformation of B lymphoma cell line BJAB by Epstein-Barr virus-encoded small RNAs. FEBS Lett 2000, 484:153-158.
    • (2000) FEBS Lett , vol.484 , pp. 153-158
    • Yamamoto, N.1    Takizawa, T.2    Iwanaga, Y.3    Shimizu, N.4    Yamamoto, N.5
  • 27
    • 0036500131 scopus 로고    scopus 로고
    • Epstein-Barr virus RNA confers resistance to interferon-alpha-induced apoptosis in Burkitt's lymphoma
    • Nanbo A., Inoue K., Adachi-Takasawa K., Takada K. Epstein-Barr virus RNA confers resistance to interferon-alpha-induced apoptosis in Burkitt's lymphoma. EMBO J 2002, 21:954-965.
    • (2002) EMBO J , vol.21 , pp. 954-965
    • Nanbo, A.1    Inoue, K.2    Adachi-Takasawa, K.3    Takada, K.4
  • 28
    • 25144457575 scopus 로고    scopus 로고
    • - RNA confers resistance to apoptosis mediated through Fas by blocking the PKR pathway in human epithelial intestine 407 cells
    • - RNA confers resistance to apoptosis mediated through Fas by blocking the PKR pathway in human epithelial intestine 407 cells. J Virol 2005, 79:12280-12285.
    • (2005) J Virol , vol.79 , pp. 12280-12285
    • Nanbo, A.1    Yoshiyama, H.2    Takada, K.3
  • 29
    • 0025169060 scopus 로고
    • Novel transcription from the Epstein-Barr virus terminal EcoRI fragment, DIJhet, in a nasopharyngeal carcinoma
    • Gilligan K.J., Sato H., Rajadurai P., Busson P., Young L., Rickinson A., et al. Novel transcription from the Epstein-Barr virus terminal EcoRI fragment, DIJhet, in a nasopharyngeal carcinoma. J Virol 1990, 64:4948-4956.
    • (1990) J Virol , vol.64 , pp. 4948-4956
    • Gilligan, K.J.1    Sato, H.2    Rajadurai, P.3    Busson, P.4    Young, L.5    Rickinson, A.6
  • 30
    • 0028890514 scopus 로고
    • Structural analyses of the Epstein-Barr virus BamHI A transcripts
    • Sadler R.H., Raab-Traub N. Structural analyses of the Epstein-Barr virus BamHI A transcripts. J Virol 1995, 69:1132-1141.
    • (1995) J Virol , vol.69 , pp. 1132-1141
    • Sadler, R.H.1    Raab-Traub, N.2
  • 31
    • 0035129844 scopus 로고    scopus 로고
    • Epstein-Barr virus BamHI-A rightward transcript-encoded RPMS protein interacts with the CBF1-associated corepressor CIR to negatively regulate the activity of EBNA2 and NotchIC
    • Zhang J., Chen H., Weinmaster G., Hayward S.D. Epstein-Barr virus BamHI-A rightward transcript-encoded RPMS protein interacts with the CBF1-associated corepressor CIR to negatively regulate the activity of EBNA2 and NotchIC. J Virol 2001, 75:2946-2956.
    • (2001) J Virol , vol.75 , pp. 2946-2956
    • Zhang, J.1    Chen, H.2    Weinmaster, G.3    Hayward, S.D.4
  • 32
    • 0035706221 scopus 로고    scopus 로고
    • BARF-1 gene as an EBV encoded oncogene
    • Ooka T. BARF-1 gene as an EBV encoded oncogene. Epstein-Barr Virus Rep 2001, 8:177-182.
    • (2001) Epstein-Barr Virus Rep , vol.8 , pp. 177-182
    • Ooka, T.1
  • 33
    • 0024386075 scopus 로고
    • A transforming function of the BARF1 gene encoded by Epstein-Barr virus
    • Wei M.X., Ooka T. A transforming function of the BARF1 gene encoded by Epstein-Barr virus. EMBO J 1989, 8:2897-2903.
    • (1989) EMBO J , vol.8 , pp. 2897-2903
    • Wei, M.X.1    Ooka, T.2
  • 34
    • 0030875250 scopus 로고    scopus 로고
    • Establishment of a monkey epithelial cell line with the BARF1 open reading frame from Epstein-Barr virus
    • Wei M.X., De Turenne-Tessier M., Decaussin G., Benet G., Ooka T. Establishment of a monkey epithelial cell line with the BARF1 open reading frame from Epstein-Barr virus. Oncogene 1997, 14:3073-3081.
    • (1997) Oncogene , vol.14 , pp. 3073-3081
    • Wei, M.X.1    De Turenne-Tessier, M.2    Decaussin, G.3    Benet, G.4    Ooka, T.5
  • 35
    • 0028281782 scopus 로고
    • Expression and tumorigenicity of the Epstein-Barr virus BARF1 gene in human Louckes B-lymphocyte cell line
    • Wei M.X., Moulin J.C., Decaussin G., Berger F., Ooka T. Expression and tumorigenicity of the Epstein-Barr virus BARF1 gene in human Louckes B-lymphocyte cell line. Cancer Res 1994, 54:1843-1848.
    • (1994) Cancer Res , vol.54 , pp. 1843-1848
    • Wei, M.X.1    Moulin, J.C.2    Decaussin, G.3    Berger, F.4    Ooka, T.5
  • 36
    • 0037333993 scopus 로고    scopus 로고
    • Malignant transformation of Epstein-Barr virus-negative Akata cells by introduction of the BARF1 gene carried by Epstein-Barr virus
    • Sheng W., Decaussin G., Ligout A., Takada K., Ooka T. Malignant transformation of Epstein-Barr virus-negative Akata cells by introduction of the BARF1 gene carried by Epstein-Barr virus. J Virol 2003, 77:3859-3865.
    • (2003) J Virol , vol.77 , pp. 3859-3865
    • Sheng, W.1    Decaussin, G.2    Ligout, A.3    Takada, K.4    Ooka, T.5
  • 39
    • 44449174967 scopus 로고    scopus 로고
    • Cyclin D1 expression is induced by viral BARF1 and is overexpressed in EBV-associated gastric cancer
    • Wiech T., Nikolopoulos E., Lassman S., Heidt T., Schöpflin A., Sarbia M., et al. Cyclin D1 expression is induced by viral BARF1 and is overexpressed in EBV-associated gastric cancer. Virchows Arch 2008, 452:621-627.
    • (2008) Virchows Arch , vol.452 , pp. 621-627
    • Wiech, T.1    Nikolopoulos, E.2    Lassman, S.3    Heidt, T.4    Schöpflin, A.5    Sarbia, M.6
  • 40
    • 0031977661 scopus 로고    scopus 로고
    • The Epstein-Barr virus BARF1 gene encodes a novel, soluble colony-stimulating factor-1 receptor
    • Strockbine L.D., Cohen J.I., Farrah T., Lyman S.D., Wagener F., DuBose R.F., et al. The Epstein-Barr virus BARF1 gene encodes a novel, soluble colony-stimulating factor-1 receptor. J Virol 1998, 72:4015-4021.
    • (1998) J Virol , vol.72 , pp. 4015-4021
    • Strockbine, L.D.1    Cohen, J.I.2    Farrah, T.3    Lyman, S.D.4    Wagener, F.5    DuBose, R.F.6
  • 41
    • 0028839045 scopus 로고
    • Transcriptional regulation of the c-fms (CSF-1R) proto-oncogene in human breast carcinoma cells by glucocorticoids
    • Sapi E., Flick M.B., Gilmore-Hebert M., Rodov S., Kacinski B.M. Transcriptional regulation of the c-fms (CSF-1R) proto-oncogene in human breast carcinoma cells by glucocorticoids. Oncogene 1995, 10:529-542.
    • (1995) Oncogene , vol.10 , pp. 529-542
    • Sapi, E.1    Flick, M.B.2    Gilmore-Hebert, M.3    Rodov, S.4    Kacinski, B.M.5
  • 42
    • 0035911221 scopus 로고    scopus 로고
    • Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy
    • Lin E.Y., Nguyen A.V., Russell R.G., Pollard J.W. Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. J Exp Med 2001, 193:727-739.
    • (2001) J Exp Med , vol.193 , pp. 727-739
    • Lin, E.Y.1    Nguyen, A.V.2    Russell, R.G.3    Pollard, J.W.4
  • 43
    • 0031694530 scopus 로고    scopus 로고
    • Nucleic acid sequence-based amplification, a new method for analysis of spliced and unspliced Epstein-Barr virus latent transcripts, and its comparison with reverse transcriptase PCR
    • Brink A.A., Vervoort M.B., Middeldorp J.M., Meijer C.J., van den Brule A.J. Nucleic acid sequence-based amplification, a new method for analysis of spliced and unspliced Epstein-Barr virus latent transcripts, and its comparison with reverse transcriptase PCR. J Clin Microbiol 1998, 36:3164-3169.
    • (1998) J Clin Microbiol , vol.36 , pp. 3164-3169
    • Brink, A.A.1    Vervoort, M.B.2    Middeldorp, J.M.3    Meijer, C.J.4    van den Brule, A.J.5
  • 44
    • 0034657266 scopus 로고    scopus 로고
    • Unique transcription pattern of Epstein-Barr virus (EBV) in EBV-carrying gastric adenocarcinomas: expression of the transforming BARF1 gene
    • zur Hausen A., Brink A.A.T.P., Craanen M.E., Middeldorp J.M., Meijer C.J.L.M., Vandenbrule A.J.C. Unique transcription pattern of Epstein-Barr virus (EBV) in EBV-carrying gastric adenocarcinomas: expression of the transforming BARF1 gene. Cancer Res 2000, 60:2745-2748.
    • (2000) Cancer Res , vol.60 , pp. 2745-2748
    • zur Hausen, A.1    Brink, A.A.T.P.2    Craanen, M.E.3    Middeldorp, J.M.4    Meijer, C.J.L.M.5    Vandenbrule, A.J.C.6
  • 45
    • 33745463887 scopus 로고    scopus 로고
    • Noninvasive diagnosis of nasopharyngeal carcinoma: nasopharyngeal brushings reveal high Epstein-Barr virus DNA load and carcinoma-specific viral BARF1 mRNA
    • Stevens S.J., Verkuijlen S.A., Hariwiyanto B., Harijadi, Paramita D.K., Fachiroh J., et al. Noninvasive diagnosis of nasopharyngeal carcinoma: nasopharyngeal brushings reveal high Epstein-Barr virus DNA load and carcinoma-specific viral BARF1 mRNA. Int J Cancer 2006, 119:608-614.
    • (2006) Int J Cancer , vol.119 , pp. 608-614
    • Stevens, S.J.1    Verkuijlen, S.A.2    Hariwiyanto, B.3    Harijadi Paramita, D.K.4    Fachiroh, J.5
  • 46
    • 39449102142 scopus 로고    scopus 로고
    • Reconstitution of nasopharyngeal carcinoma-type EBV infection induces tumorigenicity
    • Seto E., Ooka T., Middeldorp J., Takada K. Reconstitution of nasopharyngeal carcinoma-type EBV infection induces tumorigenicity. Cancer Res 2008, 68:1030-1036.
    • (2008) Cancer Res , vol.68 , pp. 1030-1036
    • Seto, E.1    Ooka, T.2    Middeldorp, J.3    Takada, K.4


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