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Volumn 22, Issue 3, 2012, Pages 447-449

PKM2: A gatekeeper between growth and survival

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; MEMBRANE PROTEIN; THYROID HORMONE; THYROID HORMONE BINDING PROTEINS; THYROID HORMONE-BINDING PROTEINS;

EID: 84857792816     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2011.203     Document Type: Article
Times cited : (60)

References (16)
  • 1
    • 0024261927 scopus 로고
    • 2 is phosphorylated at tyrosine residues in cells transformed by Rous sarcoma virus
    • DOI 10.1016/0014-5793(88)81014-7
    • Presek P, Reinacher M, Eigenbrodt E. Pyruvate kinase type M2 is phosphorylated at tyrosine residues in cells transformed by Rous sarcoma virus. FEBS Lett 1988; 242:194-198. (Pubitemid 19012276)
    • (1988) FEBS Letters , vol.242 , Issue.1 , pp. 194-198
    • Presek, P.1    Reinacher, M.2    Eigenbrodt, E.3
  • 2
    • 66149133551 scopus 로고    scopus 로고
    • The SUMO-E3 ligase PIAS3 targets pyruvate kinase M2
    • Spoden GA, Morandell D, Ehehalt D, et al. The SUMO-E3 ligase PIAS3 targets pyruvate kinase M2. J Cell Biochem 2009; 107:293-302.
    • (2009) J Cell Biochem , vol.107 , pp. 293-302
    • Spoden, G.A.1    Morandell, D.2    Ehehalt, D.3
  • 3
    • 34547130319 scopus 로고    scopus 로고
    • Regulation of cell proliferation by interleukin-3-induced nuclear translocation of pyruvate kinase
    • DOI 10.1074/jbc.M700094200
    • Hoshino A, Hirst JA, Fujii H. Regulation of cell proliferation by interleukin3-induced nuclear translocation of pyruvate kinase. J Biol Chem 2007; 282:17706-17711. (Pubitemid 47100326)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.24 , pp. 17706-17711
    • Hoshino, A.1    Hirst, J.A.2    Fujii, H.3
  • 5
    • 33847699250 scopus 로고    scopus 로고
    • Nuclear translocation of the tumor marker pyruvate kinase M2 induces programmed cell death
    • DOI 10.1158/0008-5472.CAN-06-2870
    • Steták A, Veress R, Ovádi J, Csermely P, Kéri G, Ullrich A. Nuclear translocation of the tumor marker pyruvate kinase M2 induces programmed cell death. Cancer Res 2007; 67:1602-1608. (Pubitemid 46383385)
    • (2007) Cancer Research , vol.67 , Issue.4 , pp. 1602-1608
    • Stetak, A.1    Veress, R.2    Ovadi, J.3    Csermely, P.4    Keri, G.5    Ullrich, A.6
  • 7
    • 40749099894 scopus 로고    scopus 로고
    • Pyruvate kinase M2 is a phosphotyrosine-binding protein
    • DOI 10.1038/nature06667, PII NATURE06667
    • Christofk HR, Vander Heiden MG, Wu N, Asara JM, Cantley LC. Pyruvate kinase M2 is a phosphotyrosine-binding protein. Nature 2008; 452:181-186. (Pubitemid 351380242)
    • (2008) Nature , vol.452 , Issue.7184 , pp. 181-186
    • Christofk, H.R.1    Vander Heiden, M.G.2    Wu, N.3    Asara, J.M.4    Cantley, L.C.5
  • 8
    • 77449131347 scopus 로고    scopus 로고
    • Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth
    • Hitosugi T, Kang S, Vander Heiden MG, et al. Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth. Sci Signal 2009; 2:ra73.
    • (2009) Sci Signal , vol.2
    • Hitosugi, T.1    Kang, S.2    Vander Heiden, M.G.3
  • 9
    • 79957567239 scopus 로고    scopus 로고
    • Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxiainducible factor 1
    • Luo W, Hu H, Chang R, et al. Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxiainducible factor 1. Cell 2011; 145:732-744.
    • (2011) Cell , vol.145 , pp. 732-744
    • Luo, W.1    Hu, H.2    Chang, R.3
  • 10
    • 82555170271 scopus 로고    scopus 로고
    • Nuclear PKM2 regulates beta-catenin transactivation upon EGFR activation
    • Yang W, Xia Y, Ji H, et al. Nuclear PKM2 regulates beta-catenin transactivation upon EGFR activation. Nature 2011; 480:118-122.
    • (2011) Nature , vol.480 , pp. 118-122
    • Yang, W.1    Xia, Y.2    Ji, H.3
  • 11
    • 75149150660 scopus 로고    scopus 로고
    • HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer
    • David CJ, Chen M, Assanah M, Canoll P, Manley JL. HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer. Nature 2010; 463:364-368.
    • (2010) Nature , vol.463 , pp. 364-368
    • David, C.J.1    Chen, M.2    Assanah, M.3    Canoll, P.4    Manley, J.L.5
  • 12
    • 82755166890 scopus 로고    scopus 로고
    • Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to antioxidant responses
    • Anastasiou D, Poulogiannis G, Asara JM, et al. Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to antioxidant responses. Science 2011; 334:1278-1283.
    • (2011) Science , vol.334 , pp. 1278-1283
    • Anastasiou, D.1    Poulogiannis, G.2    Asara, J.M.3
  • 13
    • 79952749503 scopus 로고    scopus 로고
    • Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth
    • Sun Q, Chen X, Ma J, et al. Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth. Proc Natl Acad Sci USA 2011; 108:4129-4134.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 4129-4134
    • Sun, Q.1    Chen, X.2    Ma, J.3
  • 14
    • 79959371914 scopus 로고    scopus 로고
    • Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth
    • Lv L, Li D, Zhao D, et al. Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth. Mol Cell 2011; 42:719-730.
    • (2011) Mol Cell , vol.42 , pp. 719-730
    • Lv, L.1    Li, D.2    Zhao, D.3
  • 15
    • 78650909063 scopus 로고    scopus 로고
    • Glucose metabolism induces mono-ubiquitination of histone H2B in mammalian cells
    • Gao Z, Xu CW. Glucose metabolism induces mono-ubiquitination of histone H2B in mammalian cells. Biochem Biophys Res Commun 2011; 404:428-433.
    • (2011) Biochem Biophys Res Commun , vol.404 , pp. 428-433
    • Gao, Z.1    Xu, C.W.2
  • 16
    • 40149095758 scopus 로고    scopus 로고
    • Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription
    • Lee J, Kim HK, Han YM, Kim J. Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription. Int J Biochem Cell Biol 2008; 40:1043-1054.
    • (2008) Int J Biochem Cell Biol , vol.40 , pp. 1043-1054
    • Lee, J.1    Kim, H.K.2    Han, Y.M.3    Kim, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.