Skin fragility in obese diabetic mice: Possible involvement of elevated oxidative stress and upregulation of matrix metalloproteinases

Experimental Dermatology

Volumn 21, Issue 3, 2012, Pages 178-183

  Ibuki, Ai ^a   Akase, Tomoko ^a,b   Nagase, Takashi ^a   Minematsu, Takeo ^a   Nakagami, Gojiro ^a   Horii, Motoko ^a   Sagara, Hiroshi ^c   Komeda, Takashi ^d   Kobayashi, Masayuki ^d   Shimada, Tsutomu ^e   Aburada, Masaki ^e   Yoshimura, Kotaro ^a   Sugama, Junko ^f   Sanada, Hiromi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOKAI UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d SHIBAURA INSTITUTE OF TECHNOLOGY   (Japan)

^e MUSASHINO UNIVERSITY   (Japan)

^f KANAZAWA UNIVERSITY   (Japan)

Author keywords

Collagen; Matrix metalloproteinases; Oxidative stress; Skin tensile strength; Subcutaneous adipose tissue

Indexed keywords

ALPHA TOCOPHEROL; COLLAGEN FIBER; GELATINASE A; HEME OXYGENASE 1; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE 14; MESSENGER RNA;

ABDOMINAL SUBCUTANEOUS FAT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DENSITY; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME RELEASE; GENE EXPRESSION; MALE; MOUSE; NONHUMAN; OBESITY; OXIDATIVE STRESS; PROTEIN DENATURATION; SCANNING ELECTRON MICROSCOPY; SKIN FRAGILITY; TENSILE STRENGTH; VITAMIN SUPPLEMENTATION;

ANIMALS; DIABETES MELLITUS; DISEASE MODELS, ANIMAL; FIBRILLAR COLLAGENS; GENE EXPRESSION PROFILING; MALE; MATRIX METALLOPROTEINASES; MICE; MICE, OBESE; MICROSCOPY, ELECTRON, SCANNING; OBESITY; OXIDATIVE STRESS; REAL-TIME POLYMERASE CHAIN REACTION; SKIN; SUBCUTANEOUS FAT; TENSILE STRENGTH; UP-REGULATION;

EID: 84857789292     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/j.1600-0625.2011.01409.x     Document Type: Article

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