MMP-8 promotes polymorphonuclear cell migration through collagen barriers in obliterative bronchiolitis

Journal of Leukocyte Biology

Volumn 87, Issue 1, 2010, Pages 69-77

  Khatwa, Umakanth A ^a   Kleibrink, Bjoern E ^b   Shapiro, Steven D ^c   Subramaniam, Meera ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF DUISBURG ESSEN   (Germany)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Cell trafficking; Inflammation; Neutrophils

Indexed keywords

COLLAGEN; ILOMASTAT; NEUTROPHIL COLLAGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHIOLITIS OBLITERANS; CELL MIGRATION; CONTROLLED STUDY; CROSS LINKING; ENZYME ACTIVITY; EOSINOPHIL; EXTRACELLULAR MATRIX; FEMALE; LEUKOCYTE COUNT; LUNG FIBROSIS; MONONUCLEAR CELL; MOUSE; NEUTROPHIL; NONHUMAN; PATHOPHYSIOLOGY; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; WILD TYPE;

ANIMALS; BLOOD CELLS; BONE MARROW CELLS; BRONCHIOLITIS OBLITERANS; CELLS, CULTURED; CHEMOTAXIS, LEUKOCYTE; COLLAGEN; EXTRACELLULAR MATRIX; FEMALE; GELS; MATRIX METALLOPROTEINASE 8; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUTROPHILS; TRACHEA; TRANSPLANTATION, HETEROTOPIC;

MUS;

EID: 74949090777     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0509361     Document Type: Article

References (38)

1. Parks, W. C., Shapiro, S. D. (2001) Matrix metalloproteinases in lung biology. Respir. Res. 2, 10-19.
2. Parks, W. C., Wilson, C. L., Lopez-Boado, Y. S. (2004) Matrix metalloproteinases as modulators of inflammation and innate immunity. Nat. Rev. Immunol. 4, 617-629.
3. Diekmann, O., Tschesche, H. (1994) Degradation of kinins, angiotensins and substance P by polymorphonuclear matrix metalloproteinases MMP 8 and MMP 9. Braz. J. Med. Biol. Res. 27, 1865-1876.
4. Prikk, K., Maisi, P., Pirila, E., Sepper, R., Salo, T., Wahlgren, J., Sorsa, T. (2001) In vivo collagenase-2 (MMP-8) expression by human bronchial epithelial cells and monocytes/macrophages in bronchiectasis. J. Pathol. 194, 232-238.
5. Prikk, K., Maisi, P., Pirila, E., Reintam, M. A., Salo, T., Sorsa, T., Sepper, R. (2002) Airway obstruction correlates with collagenase-2 (MMP-8) expression and activation in bronchial asthma. Lab. Invest. 82, 1535-1545.
6. Owen, C. A., Hu, Z., Lopez-Otin, C., Shapiro, S. D. (2004) Membranebound matrix metalloproteinase-8 on activated polymorphonuclear cells is a potent, tissue inhibitor of metalloproteinase-resistant collagenase and serpinase. J. Immunol. 172, 7791-7803.
7. Hanemaaijer, R., Sorsa, T., Konttinen, Y. T., Ding, Y., Sutinen, M., Visser, H., van Hinsbergh, V. W., Helaakoski, T., Kainulainen, T., Ronka, H., Tschesche, H., Salo, T. (1997) Matrix metalloproteinase-8 is expressed in rheumatoid synovial fibroblasts and endothelial cells. Regulation by tumor necrosis factor-α and doxycycline. J. Biol. Chem. 272, 31504-31509.
8. Herman, M. P., Sukhova, G. K., Libby, P., Gerdes, N., Tang, N., Horton, D. B., Kilbride, M., Breitbart, R. E., Chun, M., Schonbeck, U. (2001) Expression of neutrophil collagenase (matrix metalloproteinase-8) in human atheroma: a novel collagenolytic pathway suggested by transcriptional profiling. Circulation 104, 1899-1904.
9. Naesse, E. P., Schreurs, O., Helgeland, K., Schenck, K., Steinsvoll, S. (2003) Matrix metalloproteinases and their inhibitors in gingival mast cells in persons with and without human immunodeficiency virus infection. J. Periodontal Res. 38, 575-582.
10. Cole, A. A., Chubinskaya, S., Schumacher, B., Huch, K., Szabo, G., Yao, J., Mikecz, K., Hasty, K. A., Kuettner, K. E. (1996) Chondrocyte matrix metalloproteinase-8. Human articular chondrocytes express neutrophil collagenase. J. Biol. Chem. 271, 11023-11026.
11. Ratjen, F., Hartog, C. M., Paul, K., Wermelt, J., Braun, J. (2002) Matrix metalloproteases in BAL fluid of patients with cystic fibrosis and their modulation by treatment with dornase α. Thorax 57, 930-934.
12. Matsuki, H., Fujimoto, N., Iwata, K., Knauper, V., Okada, Y., Hayakawa, T. (1996) A one-step sandwich enzyme immunoassay for human matrix metalloproteinase 8 (neutrophil collagenase) using monoclonal antibodies. Clin. Chim. Acta 244, 129-143.
13. Allport, J. R., Lim, Y. C., Shipley, J. M., Senior, R. M., Shapiro, S. D., Matsuyoshi, N., Vestweber, D., Luscinskas, F. W. (2002) Neutrophils from MMP-9- or neutrophil elastase-deficient mice show no defect in transendothelial migration under flow in vitro. J. Leukoc. Biol. 71, 821-828.
14. Nwomeh, B. C., Liang, H. X., Cohen, I. K., Yager, D. R. (1999) MMP-8 is the predominant collagenase in healing wounds and nonhealing ulcers. J. Surg. Res. 81, 189-195.
15. Boehler, A., Estenne, M. (2003) Post-transplant bronchiolitis obliterans. Eur. Respir. J. 22, 1007-1018.
16. McDyer, J. F. (2007) Human and murine obliterative bronchiolitis in transplant. Proc. Am. Thorac. Soc. 4, 37-43.
17. Belperio, J. A., Weigt, S. S., Fishbein, M. C., Lynch III, J. P. (2009) Chronic lung allograft rejection: mechanisms and therapy. Proc. Am. Thorac. Soc. 6, 108-121.
18. Taghavi, S., Krenn, K., Jaksch, P., Klepetko, W., Aharinejad, S. (2005) Broncho-alveolar lavage matrix metalloproteases as a sensitive measure of bronchiolitis obliterans. Am. J. Transplant. 5, 1548-1552.
19. Miura, M., El-Sawy, T., Fairchild, R. L. (2003) Neutrophils mediate parenchymal tissue necrosis and accelerate the rejection of complete major histocompatibility complex-disparate cardiac allografts in the absence of interferon-γ. Am. J. Pathol. 162, 509-519.
20. Vanaudenaerde, B. M., Meyts, I., Vos, R., Geudens, N., De Wever, W., Verbeken, E. K., Van Raemdonck, D. E., Dupont, L. J., Verleden, G. M. (2008) A dichotomy in bronchiolitis obliterans syndrome after lung transplantation revealed by azithromycin therapy. Eur. Respir. J. 32, 832-843.
21. Sato, M., Liu, M., Anraku, M., Ogura, T., D'Cruz, G., Alman, B. A., Waddell, T. K., Kim, E., Zhang, L., Keshavjee, S. (2008) Allograft airway fibrosis in the pulmonary milieu: a disorder of tissue remodeling. Am. J. Transplant. 8, 517-528.
22. Hertz, M. I., Jessurun, J., King, M. B., Savik, S. K., Murray, J. J. (1993) Reproduction of the obliterative bronchiolitis lesion after heterotopic transplantation of mouse airways. Am. J. Pathol. 142, 1945-1951.
23. Galardy, R. E., Cassabonne, M. E., Giese, C., Gilbert, J. H., Lapierre, F., Lopez, H., Schaefer, M. E., Stack, R., Sullivan, M., Summers, B., et al. (1994) Low molecular weight inhibitors in corneal ulceration. Ann. N. Y. Acad. Sci. 732, 315-323.
24. Goo, H. C., Hwang, Y. S., Choi, Y. R., Cho, H. N., Suh, H. (2003) Development of collagenase-resistant collagen and its interaction with adult human dermal fibroblasts. Biomaterials 24, 5099-5113.
25. Neurohr, C., Huppmann, P., Samweber, B., Leuschner, S., Zimmermann, G., Leuchte, H., Baumgartner, R., Hatz, R., Frey, L., Ueberfuhr, P., Bittmann, I., Behr, J. (2009) Prognostic value of bronchoalveolar lavage neutrophilia in stable lung transplant recipients. J. Heart Lung Transplant. 28, 468-474.
26. Hasty, K. A., Jeffrey, J. J., Hibbs, M. S., Welgus, H. G. (1987) The collagen substrate specificity of human neutrophil collagenase. J. Biol. Chem. 262, 10048-10052.
27. Balbin, M., Fueyo, A., Tester, A. M., Pendas, A. M., Pitiot, A. S., Astudillo, A., Overall, C. M., Shapiro, S. D., Lopez-Otin, C. (2003) Loss of collagenase-2 confers increased skin tumor susceptibility to male mice. Nat. Genet. 35, 252-257.
28. Gutierrez-Fernandez, A., Inada, M., Balbin, M., Fueyo, A., Pitiot, A. S., Astudillo, A., Hirose, K., Hirata, M., Shapiro, S. D., Noel, A., Werb, Z., Krane, S. M., Lopez-Otin, C., Puente, X. S. (2007) Increased inflammation delays wound healing in mice deficient in collagenase-2 (MMP-8). FASEB J. 21, 2580-2591.
29. Fernandez, F. G., McKane, B., Marshbank, S., Patterson, G. A., Mohanakumar, T. (2005) Inhibition of obliterative airway disease development following heterotopic murine tracheal transplantation by costimulatory molecule blockade using anti-CD40 ligand alone or in combination with donor bone marrow. J. Heart Lung Transplant. 24, S232-S238.
30. Sabeh, F., Ota, I., Holmbeck, K., Birkedal-Hansen, H., Soloway, P., Balbin, M., Lopez-Otin, C., Shapiro, S., Inada, M., Krane, S., Allen, E., Chung, D., Weiss, S. J. (2004) Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP. J. Cell Biol. 167, 769-781.
31. Even-Ram, S., Yamada, K. M. (2005) Cell migration in 3D matrix. Curr. Opin. Cell Biol. 17, 524-532.
32. Lindbom, L., Werr, J. (2002) Integrin-dependent neutrophil migration in extravascular tissue. Semin. Immunol. 14, 115-121.
33. Wolf, K., Mazo, I., Leung, H., Engelke, K., von Andrian, U. H., Deryugina, E. I., Strongin, A. Y., Brocker, E. B., Friedl, P. (2003) Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis. J. Cell Biol. 160, 267-277.
34. Gaggar, A., Jackson, P. L., Noerager, B. D., O'Reilly, P. J., McQuaid, D. B., Rowe, S. M., Clancy, J. P., Blalock, J. E. (2008) A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation. J. Immunol. 180, 5662-5669.
35. Hardison, M. T., Galin, F. S., Calderon, C. E., Djekic, U. V., Parker, S. B., Wille, K. M., Jackson, P. L., Oster, R. A., Young, K. R., Blalock, J. E., Gaggar, A. (2009) The presence of a matrix-derived neutrophil chemoattractant in bronchiolitis obliterans syndrome after lung transplantation. J. Immunol. 182, 4423-4431.
36. Van Lint, P., Wielockx, B., Puimege, L., Noel, A., Lopez-Otin, C., Libert, C. (2005) Resistance of collagenase-2 (matrix metalloproteinase-8)- deficient mice to TNF-induced lethal hepatitis. J. Immunol. 175, 7642-7649.
37. Tester, A. M., Cox, J. H., Connor, A. R., Starr, A. E., Dean, R. A., Puente, X. S., Lopez-Otin, C., Overall, C. M. (2007) LPS responsiveness and neutrophil chemotaxis in vivo require PMN MMP-8 activity. PLoS ONE 2, e312.
38. Van Lint, P., Libert, C. (2007) Chemokine and cytokine processing by matrix metalloproteinases and its effect on leukocyte migration and inflammation. J. Leukoc. Biol. 82, 1375-1381.