-
1
-
-
0035496231
-
Lymphostromal interactions in thymic development and function
-
Anderson G, Jenkinson EJ (2001) Lymphostromal interactions in thymic development and function. Nat. Rev. Immunol. 1, 31-40.
-
(2001)
Nat. Rev. Immunol.
, vol.1
, pp. 31-40
-
-
Anderson, G.1
Jenkinson, E.J.2
-
2
-
-
46949110881
-
Reversal of age-associated thymic atrophy: treatments, delivery, and side effects
-
Aspinall R, Mitchell W (2008) Reversal of age-associated thymic atrophy: treatments, delivery, and side effects. Exp. Gerontol. 43, 700-705.
-
(2008)
Exp. Gerontol.
, vol.43
, pp. 700-705
-
-
Aspinall, R.1
Mitchell, W.2
-
3
-
-
34250212481
-
Commitment and developmental potential of extrathymic and intrathymic T cell precursors: plenty to choose from
-
Bhandoola A, von Boehmer H, Petrie HT, Zúñiga-Pflücker JC (2007) Commitment and developmental potential of extrathymic and intrathymic T cell precursors: plenty to choose from. Immunity 26, 678-689.
-
(2007)
Immunity
, vol.26
, pp. 678-689
-
-
Bhandoola, A.1
von Boehmer, H.2
Petrie, H.T.3
Zúñiga-Pflücker, J.C.4
-
4
-
-
0031726324
-
Crucial function of the pre-T-cell receptor (TCR) in TCR beta selection TCR beta allelic exclusion and alpha beta versus gamma delta lineage commitment
-
von Boehmer H, Aifantis I, Azogui O, Feinberg J, Saint-Ruf C, Zober C, Garcia C, Buer J (1998) Crucial function of the pre-T-cell receptor (TCR) in TCR beta selection, TCR beta allelic exclusion and alpha beta versus gamma delta lineage commitment. Immunol. Rev. 165, 111-119.
-
(1998)
Immunol. Rev.
, vol.165
, pp. 111-119
-
-
von Boehmer, H.1
Aifantis, I.2
Azogui, O.3
Feinberg, J.4
Saint-Ruf, C.5
Zober, C.6
Garcia, C.7
Buer, J.8
-
5
-
-
0030964085
-
Regulation of peroxisome proliferator-activated receptor gamma activity by mitogen-activated protein kinase
-
Camp HS, Tafuri SR (1997) Regulation of peroxisome proliferator-activated receptor gamma activity by mitogen-activated protein kinase. J. Biol. Chem. 272, 10811-10816.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 10811-10816
-
-
Camp, H.S.1
Tafuri, S.R.2
-
6
-
-
0032894240
-
c-Jun N-terminal kinase phosphorylates peroxisome proliferator-activated receptor-gamma1 and negatively regulates its transcriptional activity
-
Camp HS, Tafuri SR, Left T (1999) c-Jun N-terminal kinase phosphorylates peroxisome proliferator-activated receptor-gamma1 and negatively regulates its transcriptional activity. Endocrinology 140, 392-397.
-
(1999)
Endocrinology
, vol.140
, pp. 392-397
-
-
Camp, H.S.1
Tafuri, S.R.2
Left, T.3
-
7
-
-
36549062401
-
Impact of niche aging on thymic regeneration and immune reconstitution
-
Chidgey A, Dudakov J, Seach N, Boyd R (2007) Impact of niche aging on thymic regeneration and immune reconstitution. Semin. Immunol. 19, 331-340.
-
(2007)
Semin. Immunol.
, vol.19
, pp. 331-340
-
-
Chidgey, A.1
Dudakov, J.2
Seach, N.3
Boyd, R.4
-
8
-
-
54249149973
-
Adipose-immune interactions during obesity and caloric restriction: reciprocal mechanisms regulating immunity and health span
-
Dixit VD (2008) Adipose-immune interactions during obesity and caloric restriction: reciprocal mechanisms regulating immunity and health span. J. Leukoc. Biol. 84, 882-892.
-
(2008)
J. Leukoc. Biol.
, vol.84
, pp. 882-892
-
-
Dixit, V.D.1
-
9
-
-
34948853362
-
Ghrelin promotes thymopoiesis during aging
-
Dixit VD, Yang H, Sun Y, Weeraratna AT, Youm YH, Smith RG, Taub DD (2007) Ghrelin promotes thymopoiesis during aging. J. Clin. Invest. 117, 2778-2790.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 2778-2790
-
-
Dixit, V.D.1
Yang, H.2
Sun, Y.3
Weeraratna, A.T.4
Youm, Y.H.5
Smith, R.G.6
Taub, D.D.7
-
10
-
-
0031439111
-
p300 functions as a coactivator for the peroxisome proliferator-activated receptor alpha
-
Dowell P, Ishmael JE, Avram D, Peterson VJ, Nevrivy DJ, Leid M (1997) p300 functions as a coactivator for the peroxisome proliferator-activated receptor alpha. J. Biol. Chem. 272, 33435-33443.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 33435-33443
-
-
Dowell, P.1
Ishmael, J.E.2
Avram, D.3
Peterson, V.J.4
Nevrivy, D.J.5
Leid, M.6
-
11
-
-
1942518840
-
PPARs and the complex journey to obesity
-
Evans R, Barish GD, Wang YX (2004) PPARs and the complex journey to obesity. Nat. Med. 10, 1-7.
-
(2004)
Nat. Med.
, vol.10
, pp. 1-7
-
-
Evans, R.1
Barish, G.D.2
Wang, Y.X.3
-
12
-
-
0032718690
-
Analysis of the human thymic perivascular space during aging
-
Flores KG, Li J, Sempowski GD, Haynes BF, Hale LP (1999) Analysis of the human thymic perivascular space during aging. J. Clin. Invest. 104, 1031-1039.
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 1031-1039
-
-
Flores, K.G.1
Li, J.2
Sempowski, G.D.3
Haynes, B.F.4
Hale, L.P.5
-
13
-
-
0037425578
-
Years of life lost due to obesity
-
Fontaine KR, Redden DT, Wang C, Westfall AO, Allison DB (2003) Years of life lost due to obesity. JAMA 8, 187-193.
-
(2003)
JAMA
, vol.8
, pp. 187-193
-
-
Fontaine, K.R.1
Redden, D.T.2
Wang, C.3
Westfall, A.O.4
Allison, D.B.5
-
14
-
-
49149124183
-
Contribution of neural crest-derived cells in the embryonic and adult thymus
-
Foster K, Sheridan J, Veiga-Fernandes H, Roderick K, Pachnis V, Adams R, Blackburn C, Kioussis D, Coles M (2008) Contribution of neural crest-derived cells in the embryonic and adult thymus. J. Immunol. 180, 3183-3189.
-
(2008)
J. Immunol.
, vol.180
, pp. 3183-3189
-
-
Foster, K.1
Sheridan, J.2
Veiga-Fernandes, H.3
Roderick, K.4
Pachnis, V.5
Adams, R.6
Blackburn, C.7
Kioussis, D.8
Coles, M.9
-
15
-
-
34250904186
-
Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2
-
Furuhashi M, Tuncman G, Gö rgü n CZ, Makowski L, Atsumi G, Vaillancourt E, Kono K, Babaev VR, Fazio S, Linton MF, Sulsky R, Robl JA, Parker RA, Hotamisligil GS (2007) Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2. Nature 447, 959-965.
-
(2007)
Nature
, vol.447
, pp. 959-965
-
-
Furuhashi, M.1
Tuncman, G.2
Gö rgü n, C.Z.3
Makowski, L.4
Atsumi, G.5
Vaillancourt, E.6
Kono, K.7
Babaev, V.R.8
Fazio, S.9
Linton, M.F.10
Sulsky, R.11
Robl, J.A.12
Parker, R.A.13
Hotamisligil, G.S.14
-
16
-
-
35348874911
-
Developmental origin of fat: tracking obesity to its source
-
Gesta S, Tseng YH, Kahn CR (2007) Developmental origin of fat: tracking obesity to its source. Cell 131, 242-256.
-
(2007)
Cell
, vol.131
, pp. 242-256
-
-
Gesta, S.1
Tseng, Y.H.2
Kahn, C.R.3
-
17
-
-
0034234237
-
CBP/p300 in cell growth, transformation, and development
-
Goodman RH, Smolik S (2000) CBP/p300 in cell growth, transformation, and development. Genes Dev. 14, 1553-1577.
-
(2000)
Genes Dev
, vol.14
, pp. 1553-1577
-
-
Goodman, R.H.1
Smolik, S.2
-
18
-
-
0031907427
-
Perturbation of CD4+ and CD8+ T-cell repertoires during progression to AIDS and regulation of the CD4+ repertoire during antiviral therapy
-
Gorochov G, Neumann AU, Kereveur A, Parizot C, Li T, Katlama C, Karmochkine M, Raguin G, Autran B, Debré P (1998) Perturbation of CD4+ and CD8+ T-cell repertoires during progression to AIDS and regulation of the CD4+ repertoire during antiviral therapy. Nat. Med. 4, 215-221.
-
(1998)
Nat. Med.
, vol.4
, pp. 215-221
-
-
Gorochov, G.1
Neumann, A.U.2
Kereveur, A.3
Parizot, C.4
Li, T.5
Katlama, C.6
Karmochkine, M.7
Raguin, G.8
Autran, B.9
Debré, P.10
-
19
-
-
33845239216
-
Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells
-
Gray DH, Seach N, Ueno T, Milton MK, Liston A, Lew AM, Goodnow CC, Boyd RL (2006) Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells. Blood 108, 3777-3785.
-
(2006)
Blood
, vol.108
, pp. 3777-3785
-
-
Gray, D.H.1
Seach, N.2
Ueno, T.3
Milton, M.K.4
Liston, A.5
Lew, A.M.6
Goodnow, C.C.7
Boyd, R.L.8
-
20
-
-
23844472901
-
Thiazolidinediones expand body fluid volume through PPARgamma stimulation of ENaC-mediated renal salt absorption
-
Guan Y, Hao C, Cha DR, Rao R, Lu W, Kohan DE, Magnuson MA, Redha R, Zhang Y, Breyer MD (2005) Thiazolidinediones expand body fluid volume through PPARgamma stimulation of ENaC-mediated renal salt absorption. Nat. Med. 11, 861-866.
-
(2005)
Nat. Med.
, vol.11
, pp. 861-866
-
-
Guan, Y.1
Hao, C.2
Cha, D.R.3
Rao, R.4
Lu, W.5
Kohan, D.E.6
Magnuson, M.A.7
Redha, R.8
Zhang, Y.9
Breyer, M.D.10
-
21
-
-
33744826033
-
Thymic output in aged mice
-
Hale JS, Boursalian TE, Turk GL, Fink PJ (2006) Thymic output in aged mice. Proc. Natl Acad. Sci. USA 103, 8447-8452.
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 8447-8452
-
-
Hale, J.S.1
Boursalian, T.E.2
Turk, G.L.3
Fink, P.J.4
-
22
-
-
34648832073
-
Congestive heart failure and cardiovascular death in patients with prediabetes and type 2 diabetes given thiazolidinediones: a meta-analysis of randomised clinical trials
-
Lago RM, Singh PP, Nesto RW (2007) Congestive heart failure and cardiovascular death in patients with prediabetes and type 2 diabetes given thiazolidinediones: a meta-analysis of randomised clinical trials. Lancet 370, 1129-1136.
-
(2007)
Lancet
, vol.370
, pp. 1129-1136
-
-
Lago, R.M.1
Singh, P.P.2
Nesto, R.W.3
-
23
-
-
46749115113
-
PPARgamma agonists as therapeutics for the treatment of Alzheimer's disease
-
Landreth G, Jiang Q, Mandrekar S, Heneka M (2008) PPARgamma agonists as therapeutics for the treatment of Alzheimer's disease. Neurotherapeutics 5, 481-489.
-
(2008)
Neurotherapeutics
, vol.5
, pp. 481-489
-
-
Landreth, G.1
Jiang, Q.2
Mandrekar, S.3
Heneka, M.4
-
24
-
-
1142275269
-
Age-related changes in lymphocyte development and function
-
Linton PJ, Dorshkind K (2004) Age-related changes in lymphocyte development and function. Nat. Immunol. 5, 133-139.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 133-139
-
-
Linton, P.J.1
Dorshkind, K.2
-
25
-
-
58149468801
-
Diabetes and the risk of multi-system aging phenotypes: a systematic review and meta-analysis
-
Lu FP, Lin KP, Kuo HK (2009) Diabetes and the risk of multi-system aging phenotypes: a systematic review and meta-analysis. PLoS ONE 4, e4144.
-
(2009)
PLoS ONE
, vol.4
-
-
Lu, F.P.1
Lin, K.P.2
Kuo, H.K.3
-
26
-
-
67649396090
-
Thymic involution and immune reconstitution
-
Lynch HE, Goldberg GL, Chidgey A, Van den Brink MR, Boyd R, Sempowski GD (2009) Thymic involution and immune reconstitution. Trends Immunol. 30, 366-373.
-
(2009)
Trends Immunol
, vol.30
, pp. 366-373
-
-
Lynch, H.E.1
Goldberg, G.L.2
Chidgey, A.3
Van den Brink, M.R.4
Boyd, R.5
Sempowski, G.D.6
-
27
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M, Campbell LL, Polyak K, Brisken C, Yang J, Weinberg RA (2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 16, 704-715.
-
(2008)
Cell
, vol.16
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
Campbell, L.L.11
Polyak, K.12
Brisken, C.13
Yang, J.14
Weinberg, R.A.15
-
28
-
-
34548864933
-
PPARs in calorie restricted and genetically long-lived mice
-
Masternak MM, Bartke A (2007) PPARs in calorie restricted and genetically long-lived mice. PPAR Res. 2007, 1-7.
-
(2007)
PPAR Res
, vol.2007
, pp. 1-7
-
-
Masternak, M.M.1
Bartke, A.2
-
29
-
-
50049090547
-
The effect of thiazolidinediones on BMD and osteoporosis
-
McDonough AK, Rosenthal RS, Cao X, Saag KG (2008) The effect of thiazolidinediones on BMD and osteoporosis. Nat. Clin. Pract. Endocrinol. Metab. 4, 507-513.
-
(2008)
Nat. Clin. Pract. Endocrinol. Metab.
, vol.4
, pp. 507-513
-
-
McDonough, A.K.1
Rosenthal, R.S.2
Cao, X.3
Saag, K.G.4
-
30
-
-
0030035583
-
The aging immune system: primer and prospectus
-
Miller RA (1996) The aging immune system: primer and prospectus. Science 273, 70-74.
-
(1996)
Science
, vol.273
, pp. 70-74
-
-
Miller, R.A.1
-
31
-
-
47849086589
-
Diabetes and aging: epidemiologic overview
-
Morley JE (2008) Diabetes and aging: epidemiologic overview. Clin. Geriatr. Med. 24, 395-405.
-
(2008)
Clin. Geriatr. Med.
, vol.24
, pp. 395-405
-
-
Morley, J.E.1
-
32
-
-
45949085887
-
Neural crest origin of perivascular mesenchyme in the adult thymus
-
Müller SM, Stolt CC, Terszowski G, Blum C, Amagai T, Kessaris N, Iannarelli P, Richardson WD, Wegner M, Rodewald HR (2008) Neural crest origin of perivascular mesenchyme in the adult thymus. J. Immunol. 180, 5344-5351.
-
(2008)
J. Immunol.
, vol.180
, pp. 5344-5351
-
-
Müller, S.M.1
Stolt, C.C.2
Terszowski, G.3
Blum, C.4
Amagai, T.5
Kessaris, N.6
Iannarelli, P.7
Richardson, W.D.8
Wegner, M.9
Rodewald, H.R.10
-
33
-
-
40549089870
-
Growth hormone enhances thymic function in HIV-1-infected adults
-
Napolitano LA, Schmidt D, Gotway MB, Ameli N, Filbert EL, Ng MM, Clor JL, Epling L, Sinclair E, Baum PD, Li K, Killian ML, Bacchetti P, McCune JM (2008) Growth hormone enhances thymic function in HIV-1-infected adults. J. Clin. Invest. 118, 1085-1098.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 1085-1098
-
-
Napolitano, L.A.1
Schmidt, D.2
Gotway, M.B.3
Ameli, N.4
Filbert, E.L.5
Ng, M.M.6
Clor, J.L.7
Epling, L.8
Sinclair, E.9
Baum, P.D.10
Li, K.11
Killian, M.L.12
Bacchetti, P.13
McCune, J.M.14
-
34
-
-
33646937694
-
Thymic output and functionality of the IL-7/IL-7 receptor system in centenarians: implications for the neolymphogenesis at the limit of human life
-
Nasi M, Troiano L, Lugli E, Pinti M, Ferraresi R, Monterastelli E, Mussi C, Salvioli G, Franceschi C, Cossarizza A (2006) Thymic output and functionality of the IL-7/IL-7 receptor system in centenarians: implications for the neolymphogenesis at the limit of human life. Aging Cell 5, 167-175.
-
(2006)
Aging Cell
, vol.5
, pp. 167-175
-
-
Nasi, M.1
Troiano, L.2
Lugli, E.3
Pinti, M.4
Ferraresi, R.5
Monterastelli, E.6
Mussi, C.7
Salvioli, G.8
Franceschi, C.9
Cossarizza, A.10
-
35
-
-
84867789950
-
-
National Institute on Aging, National Institutes of Health. Publication No. 07-6134, March 2007
-
National Institute on Aging, National Institutes of Health. Publication No. 07-6134, March 2007.
-
-
-
-
36
-
-
67650504733
-
Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment
-
Naveiras O, Nardi V, Wenzel PL, Hauschka PV, Fahey F, Daley GQ (2009) Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment. Nature 460, 259-263.
-
(2009)
Nature
, vol.460
, pp. 259-263
-
-
Naveiras, O.1
Nardi, V.2
Wenzel, P.L.3
Hauschka, P.V.4
Fahey, F.5
Daley, G.Q.6
-
37
-
-
21044451726
-
The influence of age on T cell generation and TCR diversity
-
Naylor K, Li G, Vallejo AN, Lee WW, Koetz K, Bryl E, Witkowski J, Fulbright J, Weyand CM, Goronzy JJ (2005) The influence of age on T cell generation and TCR diversity. J. Immunol. 174, 7446-7452.
-
(2005)
J. Immunol.
, vol.174
, pp. 7446-7452
-
-
Naylor, K.1
Li, G.2
Vallejo, A.N.3
Lee, W.W.4
Koetz, K.5
Bryl, E.6
Witkowski, J.7
Fulbright, J.8
Weyand, C.M.9
Goronzy, J.J.10
-
39
-
-
0027251463
-
The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments
-
Pannetier C, Cochet M, Darche S, Casrouge A, Zöller M, Kourilsky P (1993) The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments. Proc. Natl Acad. Sci. USA 90, 4319-4323.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 4319-4323
-
-
Pannetier, C.1
Cochet, M.2
Darche, S.3
Casrouge, A.4
Zöller, M.5
Kourilsky, P.6
-
40
-
-
66649108800
-
Increased risk of type 2 diabetes in elderly twins
-
Poulsen P, Grunnet LG, Pilgaard K, Storgaard H, Alibegovic A, Sonne MP, Carstensen B, Beck-Nielsen H, Vaag A (2009) Increased risk of type 2 diabetes in elderly twins. Diabetes 58, 1350-1355.
-
(2009)
Diabetes
, vol.58
, pp. 1350-1355
-
-
Poulsen, P.1
Grunnet, L.G.2
Pilgaard, K.3
Storgaard, H.4
Alibegovic, A.5
Sonne, M.P.6
Carstensen, B.7
Beck-Nielsen, H.8
Vaag, A.9
-
41
-
-
33846877211
-
Maintenance of adiponectin attenuates insulin resistance induced by dietary conjugated linoleic acid in mice
-
Purushotham A, Wendel AA, Liu LF, Belury MA (2007) Maintenance of adiponectin attenuates insulin resistance induced by dietary conjugated linoleic acid in mice. J. Lipid Res. 48, 444-452.
-
(2007)
J. Lipid Res.
, vol.48
, pp. 444-452
-
-
Purushotham, A.1
Wendel, A.A.2
Liu, L.F.3
Belury, M.A.4
-
42
-
-
34547661569
-
Safety issues and prospects for future generations of PPAR modulators
-
Rubenstrunk A, Hanf R, Hum DW, Fruchart JC, Staels B (2007) Safety issues and prospects for future generations of PPAR modulators. Biochim. Biophys. Acta 1771, 1065-1081.
-
(2007)
Biochim. Biophys. Acta
, vol.1771
, pp. 1065-1081
-
-
Rubenstrunk, A.1
Hanf, R.2
Hum, D.W.3
Fruchart, J.C.4
Staels, B.5
-
43
-
-
0029995670
-
Thiazolidinediones in the treatment of insulin resistance and type II diabetes
-
Saltiel AR, Olefsky JM (1996) Thiazolidinediones in the treatment of insulin resistance and type II diabetes. Diabetes 45, 1661-1669.
-
(1996)
Diabetes
, vol.45
, pp. 1661-1669
-
-
Saltiel, A.R.1
Olefsky, J.M.2
-
44
-
-
70349664158
-
Evidence of premature immune aging in patients thymectomized during early childhood
-
Sauce D, Larsen M, Fastenackels S, Duperrier A, Keller M, Grubeck-Loebenstein B, Ferrand C, Debré P, Sidi D, Appay V (2009) Evidence of premature immune aging in patients thymectomized during early childhood. J. Clin. Invest. 119, 3070-3078.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3070-3078
-
-
Sauce, D.1
Larsen, M.2
Fastenackels, S.3
Duperrier, A.4
Keller, M.5
Grubeck-Loebenstein, B.6
Ferrand, C.7
Debré, P.8
Sidi, D.9
Appay, V.10
-
45
-
-
0036198778
-
T cell receptor excision circle assessment of thymopoiesis in aging mice
-
Sempowski GD, Gooding ME, Liao HX, Le PT, Haynes BF (2002) T cell receptor excision circle assessment of thymopoiesis in aging mice. Mol. Immunol. 8, 841-848.
-
(2002)
Mol. Immunol.
, vol.8
, pp. 841-848
-
-
Sempowski, G.D.1
Gooding, M.E.2
Liao, H.X.3
Le, P.T.4
Haynes, B.F.5
-
46
-
-
67650729748
-
Prospects for life span extension
-
Sierra F, Hadley E, Suzman R, Hodes R (2009) Prospects for life span extension. Annu. Rev. Med. 60, 457-469.
-
(2009)
Annu. Rev. Med.
, vol.60
, pp. 457-469
-
-
Sierra, F.1
Hadley, E.2
Suzman, R.3
Hodes, R.4
-
47
-
-
0034847431
-
Prospects for prevention and treatment of cancer with selective PPARgamma modulators (SPARMs)
-
Sporn MB, Suh N, Mangelsdorf DJ (2001) Prospects for prevention and treatment of cancer with selective PPARgamma modulators (SPARMs). Trends Mol. Med. 7, 395-400.
-
(2001)
Trends Mol. Med.
, vol.7
, pp. 395-400
-
-
Sporn, M.B.1
Suh, N.2
Mangelsdorf, D.J.3
-
48
-
-
23644456172
-
Therapeutic roles of peroxisome proliferator-activated receptor agonists
-
Staels B, Fruchart JC (2005) Therapeutic roles of peroxisome proliferator-activated receptor agonists. Diabetes 54, 2460-2470.
-
(2005)
Diabetes
, vol.54
, pp. 2460-2470
-
-
Staels, B.1
Fruchart, J.C.2
-
49
-
-
23044433753
-
Homeostasis and the age-associated defect of CD4 T cells
-
Swain S, Clise-Dwyer K, Haynes L (2005) Homeostasis and the age-associated defect of CD4 T cells. Semin. Immunol. 17, 370-377.
-
(2005)
Semin. Immunol.
, vol.17
, pp. 370-377
-
-
Swain, S.1
Clise-Dwyer, K.2
Haynes, L.3
-
50
-
-
20344371900
-
Insights into thymic aging and regeneration
-
Taub DD, Longo DL (2005) Insights into thymic aging and regeneration. Immunol. Rev. 205, 72-93.
-
(2005)
Immunol. Rev.
, vol.205
, pp. 72-93
-
-
Taub, D.D.1
Longo, D.L.2
-
51
-
-
50649097541
-
Fat and beyond: the diverse biology of PPARgamma
-
Tontonoz P, Spiegelman BM (2008) Fat and beyond: the diverse biology of PPARgamma. Annu. Rev. Biochem. 77, 289-312.
-
(2008)
Annu. Rev. Biochem.
, vol.77
, pp. 289-312
-
-
Tontonoz, P.1
Spiegelman, B.M.2
-
52
-
-
36849034568
-
PPAR-gamma regulates osteoclastogenesis in mice
-
Wan Y, Chong LW, Evans RM (2007) PPAR-gamma regulates osteoclastogenesis in mice. Nat. Med. 13, 1496-1503.
-
(2007)
Nat. Med.
, vol.13
, pp. 1496-1503
-
-
Wan, Y.1
Chong, L.W.2
Evans, R.M.3
-
53
-
-
38049059518
-
Forecasting the obesity epidemic in the aging U S. population
-
Wang YC, Colditz GA, Kuntz KM (2007) Forecasting the obesity epidemic in the aging U.S. population. Obesity 15, 2855-2865.
-
(2007)
Obesity
, vol.15
, pp. 2855-2865
-
-
Wang, Y.C.1
Colditz, G.A.2
Kuntz, K.M.3
-
54
-
-
41149170727
-
Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus
-
Yager EJ, Ahmed M, Lanzer K, Randall TD, Woodland DL, Blackman MA (2008) Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus. J. Exp. Med. 205, 711-723.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 711-723
-
-
Yager, E.J.1
Ahmed, M.2
Lanzer, K.3
Randall, T.D.4
Woodland, D.L.5
Blackman, M.A.6
-
55
-
-
70449701826
-
Obesity accelerates thymic aging
-
Yang H, Youm YH, Vandanmagsar B, Rood J, Kumar KG, Butler AA, Dixit VD (2009a) Obesity accelerates thymic aging. Blood 114, 3803-3812.
-
(2009)
Blood
, vol.114
, pp. 3803-3812
-
-
Yang, H.1
Youm, Y.H.2
Vandanmagsar, B.3
Rood, J.4
Kumar, K.G.5
Butler, A.A.6
Dixit, V.D.7
-
56
-
-
67149098203
-
Axin expression in thymic stromal cells contributes to agerelated increase in thymic adiposity and associated with reduced thymopoiesis independently of ghrelin signaling
-
Yang H, Youm YH, Rim JS, Galbán CJ, Vandanmagsar B, Dixit VD (2009b) Axin expression in thymic stromal cells contributes to agerelated increase in thymic adiposity and associated with reduced thymopoiesis independently of ghrelin signaling. J. Leukoc. Biol. 85, 928-938.
-
(2009)
J. Leukoc. Biol.
, vol.85
, pp. 928-938
-
-
Yang, H.1
Youm, Y.H.2
Rim, J.S.3
Galbán, C.J.4
Vandanmagsar, B.5
Dixit, V.D.6
-
57
-
-
70349231092
-
Inhibition of thymic adipogenesis by caloric restriction is coupled with reduction in age-related thymic involution
-
Yang H, Youm YH, Dixit VD (2009c) Inhibition of thymic adipogenesis by caloric restriction is coupled with reduction in age-related thymic involution. J. Immunol. 183, 3040-3052.
-
(2009)
J. Immunol.
, vol.183
, pp. 3040-3052
-
-
Yang, H.1
Youm, Y.H.2
Dixit, V.D.3
-
58
-
-
19244365650
-
Thiazolidinediones
-
Yki-Järvinen H (2004) Thiazolidinediones. N. Engl. J. Med. 351, 1106-1118.
-
(2004)
N. Engl. J. Med
, vol.351
, pp. 1106-1118
-
-
Yki-Järvinen, H.1
-
59
-
-
65449128145
-
Deficient Ghrelin receptor mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposity
-
Youm YH, Yang H, Sun Y, Smith RG, Manley NR, Dixit VD (2009) Deficient Ghrelin receptor mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposity. J. Biol. Chem. 284, 7068-7077.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 7068-7077
-
-
Youm, Y.H.1
Yang, H.2
Sun, Y.3
Smith, R.G.4
Manley, N.R.5
Dixit, V.D.6
-
60
-
-
67650996754
-
Biomarkers for epithelial-mesenchymal transitions
-
Zeisberg M, Neilson EG (2009) Biomarkers for epithelial-mesenchymal transitions. J. Clin. Invest. 119, 1429-1437.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 1429-1437
-
-
Zeisberg, M.1
Neilson, E.G.2
|