Possible interaction between B1 retrotransposon-containing sequences and β major globin gene transcriptional activation during MEL cell erythroid differentiation

Cell Biology International

Volumn 36, Issue 1, 2012, Pages 47-55

  Vizirianakis, Ioannis S ^a   Tezias, Sotirios S ^a   Amanatiadou, Elsa P ^a   Tsiftsoglou, Asterios S ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

B1 retrotransposon element; Differentiation; Erythropoiesis; Globin genes; Locus control region; MEL cells; Methylation inhibitors; Promoter activity; Silent DNA sequences

Indexed keywords

ERYTHROID KRUPPEL LIKE FACTOR; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR NF E2;

3' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; BETA GLOBIN GENE; BINDING SITE; CELL DIFFERENTIATION; CHROMOSOME 7; CONTROLLED STUDY; DNA DETERMINATION; DNA SEQUENCE; ERYTHROID CELL; GENE EXPRESSION; GENE FUNCTION; GENE INTERACTION; GENE LOCATION; GENE MAPPING; GENE SEQUENCE; GLOBIN GENE; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN LOCALIZATION; REGULATOR GENE; REPORTER GENE; RETROPOSON; STRUCTURAL HOMOLOGY; TRANSCRIPTION INITIATION;

ANIMALS; BASE SEQUENCE; BETA-GLOBINS; CELL DIFFERENTIATION; CELL LINE, TUMOR; ERYTHROID CELLS; ERYTHROPOIESIS; GATA1 TRANSCRIPTION FACTOR; GENES, REPORTER; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LEUKEMIA, ERYTHROBLASTIC, ACUTE; LOCUS CONTROL REGION; MICE; MICE, INBRED BALB C; NF-E2 TRANSCRIPTION FACTOR, P45 SUBUNIT; PROMOTER REGIONS, GENETIC; RETROELEMENTS; TRANSCRIPTIONAL ACTIVATION;

MAMMALIA; MURINAE;

EID: 84857777242     PISSN: 10656995     EISSN: 10958355     Source Type: Journal    
DOI: 10.1042/CBI20110236     Document Type: Article

References (48)

1. Apostolou E, Thanos D. Virus infection induces NF-kappaB-dependent interchromosomal associations mediating monoallelic IFN-beta gene expression. Cell 2008;134:85-96.
2. Armstrong JA, Emerson BM. NF-E2 disrupts chromatin structure at human beta-globin locus control region hypersensitive site 2 in vitro. Mol Cell Biol 1996;16:5634-44.
3. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA et al. Current protocols in molecular biology. New York: John Wiley & Sons; 1993.
4. Borchert GM, Lanier W, Davidson BL. RNA polymerase III transcribes human microRNAs. Nat Rev Strut Mol Biol 2006;13:1097-101.
5. Buzdin A, Kovalskaya-Alexandrova E, Gogvadze E, Sverdlov E. At least 50% of human-specific HERV-K (HML-2) long terminal repeats serve in vivo as active promoters for host nonrepetitive DNA transcription. J Virol 2006a;80:10752-62.
6. Buzdin A, Kovalskaya-Alexandrova E, Gogvadze E, Sverdlov E. GREM, a technique for genome-wide isolation and quantitative analysis of promoter active repeats. Nucleic Acids Res 2006b;34:e67.
7. Cantor AB, Orkin SH. Transcriptional regulation of erythropoiesis: an affair involving multiple partners. Oncogene 2002;21:3368-76.
8. Carter D, Chakalova L, Osborne C, Dai Y, Fraser P. Long-range chromatin regulatory interactions in vivo. Nat Genet 2002;32:623-6.
9. Chen L-L, DeCerbo JN, Carmichael GG. Alu element-mediated gene silencing. EMBO J 2008;27:1694-705.
10. Conley AB, Miller WJ, Jordan IK. Human cis natural antisense transcripts initiated by transposable elements. Trends Genet 2008a;24:53-6.
11. Conley AB, Piriyapongsa J, Jordan IK. Retroviral promoters in the human genome. Bioinformatics 2008b;24:1563-7.
12. Coufal NG, Garcia-Perez JL, Peng GE, Yeo GW, Mu Y, Lovci MT et al. L1 retrotransposition in human neural progenitor cells. Nature 2009;460:1127-31.
13. Djupedal I, Ekwall K. Epigenetics: heterochromatin meets RNAi. Cell Res 2009;19:282-95.
14. Duncan C, Biro PA, Choudary PV, Elder JT, Wang RRC, Forget BG et al. RNA polymerase III transcriptional units are interspersed among human non-α-globin genes. Proc Natl Acad Sci USA 1979;76:5095-9.
15. Hambor JE, Mennone J, Coon ME, Hanke JH, Kavathas P. Identification and characterization of an Alu-containing, T-cell-specific enhancer located in the last intron of the human CD8 alpha gene. Mol Cell Biol 1993;13:7056-70.
16. Harris CR, Dewan A, Zupnick A, Normart R, Gabriel A, Prives C et al. p53 responsive elements in human retrotransposons. Oncogene 2009;28:3857-65.
17. Kramerov DA, Vassetzky NS. Short retroposons in eukaryotic genomes. Int Rev Cytol 2005;247:165-221.
18. Labuda D, Sinnett D, Richer C, Deragon JM, Striker G. Evolution of mouse B1 repeats: 7SL RNA folding pattern conserved. J Mol Evol 1991;32:405-14.
19. Lai CB, Zhang Y, Rogers SL, Mager DL. Creation of the two isoforms of rodent NKG2D was driven by a B1 retrotransposon insertion. Nucleic Acids Res 2009;37:3032-43.
20. Lehnert S, Van Loo P, Thilakarathne PJ, Marynen P, Verbeke G, Schuit FC. Evidence for co-evolution between human microRNAs and Alurepeats. PLoS ONE 2009;4:e4456.
21. Muotri AR, Marchetto MC, Coufal NG, Oefner R, Yeo G, Nakashima K et al. L1 retrotransposition in neurons is modulated by MeCP2. Nature 2010;468:443-6.
22. Ostertang EM, Kazazian HH. LINEs in mind. Nature 2005;435:890-1.
23. Pink RC, Eskiw CH, Caley DP, Carter DR. Analysis of b-globin chromatin micro-environment using a novel 3C variant, 4Cv. PLoS ONE 2010;5:e13045.
24. Polak P, Domany E. Alu elements contain many binding sites for transcription factors and may play a role in regulation of developmental processes. BMC Genomics 2006;7:133.
25. Polavarapu N, Marino-Ramirez L, Landsman D, McDonald JF, Jordan IK. Evolutionary rates and patterns for human transcription factor binding sites derived from repetitive DNA. BMC Genomics 2008;9:226.
26. Reddy PM., Stamatoyannopoulos G, Papayannopoulou T, Shen CK. Genomic footprinting and sequencing of human beta-globin locus: tissue specificity and cell line artifact. J Biol Chem 1994;269:8287-95.
27. Roman-Gomez J, Jimenez-Velasco A, Agirre X, Castillejo JA, Navarro G, San Jose-Eneriz E et al. Repetitive DNA hypomethylation in the advanced phase of chronic myeloid leukemia. Leuk Res 2008;32:487-90.
28. Roman-Gomez J, Jimenez-Velasco A, Agirre X, Cervantes F, Sanchez J, Garate L et al. Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia. Oncogene 2005;24:7213-23.
29. Romanish MT, Lock WM, van de Lagemaat LN, Dunn CA, Mager DL. Repeated recruitment of LTR retrotransposons as promoters by the anti-apoptotic locus NAIP during mammalian evolution. PLoS Genet 2007;3:e10.
30. Romanish MT, Nakamura H, Lai CB, Wang Y, Mager DL. A novel protein isoform of the multicopy human NAIP gene derives from intragenic Alu SINE promoters. PLoS One 2009;4:e5761.
31. Sasaki T, Nishihara H, Hirakawa M, Fujimura K, Tanaka M, Kokubo N et al. Possible involvement of SINEs in mammalian-specific brain formation. Proc Natl Acad Sci USA 2008;105:4220-5.
32. Sawado T, Igarashi K, Groudine M. Activation of beta-major globin gene transcription is associated with recruitment of NF-E2 to the betaglobin LCR and gene promoter. Proc Natl Acad Sci USA 2001;98:10226-31.
33. Schumann GG, Gogvadze EV, Osanai-Futahashi M, Kuroki A, Münk C, Fujiwara H et al. Unique functions of repetitive transcriptomes. Int Rev Cell Mol Biol 2010;285:115-88.
34. Sharan C, Hamilton NM, Parl AK, Singh PK, Chaudhuri G. Identification and characterization of a transcriptional silencer upstream of the human BRCA2 gene. Biochem Biophys Res Commun 1999;265:285-90.
35. Spilianakis CG, Lalioti MD, Town T, Lee GR, Flavell RA. Interchromosomal associations between alternatively expressed loci. Nature 2005;435:637-45.
36. Tezias SS, Tsiftsoglou AS, Amanatiadou EP, Vizirianakis IS. Cloning and characterization of polyA- RNA transcripts encoded by activated B1-like retrotransposons in mouse erythroleukemia MEL cells exposed to methylation inhibitors. BMB Reports 2011; in press.
37. Tolhuis B, Palstra R, Splinter E, Grosveld F, de Laat W. Looping and interaction between hypersensitive sites in the active beta-globin locus. Mol Cell 2002;10:1453-65.
38. Tsiftsoglou AS, Pappas IS, Vizirianakis IS. Mechanisms involved in the induced differentiation of leukemia cells. Pharmacol Ther 2003;100:257-90.
39. Tsiftsoglou AS, Tsamadou AI, Papadopoulou LC. Heme as key regulator of major mammalian cellular functions: molecular, cellular, and pharmacological aspects. Pharmacol Ther 2006;111:327-45.
40. Tsiftsoglou AS, Vizirianakis IS, Strouboulis J. Erythropoiesis: model systems, molecular regulators, and developmental programs. IUBMB Life 2009;61:800-30.
41. Tsiftsoglou AS, Wong W, Robinson SH, Hensold J. Hemin increase production of b-like globin RNA transcripts in human erythroleukemia K-562 cells. Dev Genet 1989;10:311-7.
42. van de Lagemaat LN, Landry JR, Mager DL, Medstrand P. Transposable elements in mammals promote regulatory variation and diversification of genes with specialized functions. Trends Genet 2003;19:530-6.
43. Vidal F, Mougneau E, Glaichenhaus N, Vaigot P, Darmon M, Cuzin F. Coordinated posttranscriptional control of gene expression by modular elements including Alu-like repetitive sequences. Proc Natl Acad Sci USA 1993;90:208-12.
44. + RNA transcripts. Biochim Biophys Acta 1996;1312:8-20.
45. Vizirianakis IS, Tsiftsoglou AS. Blockade of murine erythroleukemia cell differentiation by hypomethylating agents causes accumulation of discrete small poly(A)2 RNAs hybridized to 3'-end flanking sequences of beta(major) globin gene. Biochim Biophys Acta 2005;1743:101-14.
46. Weiner AM. SINEs and LINEs: the art of biting the hand that feeds you. Curr Opin Cell Biol 2002;14:343-50.
47. Yang Z, Boffelli D, Boonmark N, Schwartz K, Lawn R. Apolipoprotein(a) gene enhancer resides within a LINE element. J Biol Chem 1998;273:891-7.
48. Zhou Y, Zheng JB, Gu X, Li W, Saunders GF. A novel Pax-6 binding site in rodent B1 repetitive elements: coevolution between developmental regulation and repeated elements? Gene 2000;245:319-28.