Interaction pattern of Arg 62 in the a-pocket of differentially disease-associated HLA-B27 subtypes suggests distinct TCR binding modes

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Nurzia, Elisa ^a   Narzi, Daniele ^b   Cauli, Alberto ^c   Mathieu, Alessandro ^c   Tedeschi, Valentina ^a   Caristi, Silvana ^a   Sorrentino, Rosa ^a   Böckmann, Rainer A ^b   Fiorillo, Maria Teresa ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ARGININE; COMPLEMENTARY DNA; EPIDERMAL GROWTH FACTOR; HLA B27 ANTIGEN; INFLUENZA A VIRUS NUCLEOPROTEIN; LATENT MEMBRANE PROTEIN 2; LYSINE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1; VIRUS NUCLEOPROTEIN; HLA B*27:05 ANTIGEN; HLA B*27:09 ANTIGEN; HLA-B*27:05 ANTIGEN; HLA-B*27:09 ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; OLIGOPEPTIDE; SOLVENT;

ALLELE; ALPHA HELIX; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANKYLOSING SPONDYLITIS; ANTIGEN RECOGNITION; ARTICLE; CD8+ T LYMPHOCYTE; CELL SURFACE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISEASE ASSOCIATION; HELA CELL; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; SALT BRIDGE; AMINO ACID SEQUENCE; CHEMISTRY; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARGININE; CONSERVED SEQUENCE; HELA CELLS; HLA-B27 ANTIGEN; HUMANS; MOLECULAR DYNAMICS SIMULATION; OLIGOPEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, ANTIGEN, T-CELL; SOLVENTS;

EID: 84857759560     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032865     Document Type: Article

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