Transcriptional regulation of the human FPR2/ALX gene: Evidence of a heritable genetic variant that impairs promoter activity

FASEB Journal

Volumn 26, Issue 3, 2012, Pages 1323-1333

  Simiele, Felice ^a   Recchiuti, Antonio ^a   Mattoscio, Domenico ^a   De Luca, Antonella ^a   Cianci, Eleonora ^a   Franchi, Sara ^a   Gatta, Valentina ^a   Parolari, Alessandro ^b,c   Werba, Josè Pablo ^b   Camera, Marina ^b,c   Favaloro, Bartolo ^a   Romano, Mario ^a  

^a UNIVERSITY OF CHIETI   (Italy)

^b CENTRO CARDIOLOGICO MONZINO   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

Inflammation; Lipoxin A 4 receptor; Methylation; Polymorphism; Sp1

Indexed keywords

G PROTEIN COUPLED RECEPTOR; LIPOXIN A; MESSENGER RNA; PROTEIN FPR2; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CARDIOVASCULAR DISEASE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA METHYLATION; FEMALE; GENE OVEREXPRESSION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; NEUTROPHIL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; RELATIVE; SINGLE NUCLEOTIDE POLYMORPHISM; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION REGULATION;

BASE SEQUENCE; BINDING SITES; BLOTTING, WESTERN; CELL LINE; CELL LINE, TUMOR; DNA METHYLATION; GENE EXPRESSION REGULATION; GENETIC VARIATION; HUMANS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECEPTORS, FORMYL PEPTIDE; RECEPTORS, LIPOXIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SP1 TRANSCRIPTION FACTOR; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION, GENETIC;

EID: 84857752617     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-198069     Document Type: Article

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