Pneumocystis elicits a STAT6-dependent, strain-specific innate immune response and airway hyperresponsiveness

American Journal of Respiratory Cell and Molecular Biology

Volumn 46, Issue 3, 2012, Pages 290-298

  Swain, Steve D ^a   Meissner, Nicole N ^a   Siemsen, Dan W ^a   McInnerney, Kate ^a   Harmsen, Allen G ^a  

^a MONTANA STATE UNIVERSITY   (United States)

Author keywords

Airway hyperresponsiveness; Pneumocystis; Pulmonary inflammation; STAT6; Strain specific

Indexed keywords

ALBUMIN; GAMMA INTERFERON; INTERLEUKIN 4; LACTATE DEHYDROGENASE; STAT6 PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; C57BL 6 MOUSE; CD4+ T LYMPHOCYTE; CELL DAMAGE; CONTROLLED STUDY; FUNGAL STRAIN; GENE EXPRESSION; GENETIC ANALYSIS; INFLAMMATORY CELL; INNATE IMMUNITY; LUNG ALVEOLUS CELL; LUNG INJURY; LUNG LAVAGE; MORBIDITY; MOUSE; MOUSE STRAIN; NATURAL KILLER CELL; NATURAL KILLER T CELL; NEUTROPHIL; NONHUMAN; PNEUMOCYSTIS; PNEUMOCYSTOSIS; RESPIRATORY FUNCTION; RESPIRATORY TRACT ALLERGY; SIGNAL TRANSDUCTION;

ALBUMINS; ANIMALS; ANTIGENS, CD1; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; CD4-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; IMMUNITY, INNATE; INTERFERON-GAMMA; INTERLEUKIN-4; L-LACTATE DEHYDROGENASE; LUNG; LUNG DISEASES, FUNGAL; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, SCID; NATURAL KILLER T-CELLS; NEUTROPHILS; PNEUMOCYSTIS INFECTIONS; RECEPTORS, INTERLEUKIN-4; RECEPTORS, INTERLEUKIN-8B; SIGNAL TRANSDUCTION; SPECIES SPECIFICITY; STAT6 TRANSCRIPTION FACTOR; TIME FACTORS; TRANSCRIPTIONAL ACTIVATION;

FUNGI; MUS; PNEUMOCYSTIS;

EID: 84857736768     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2011-0154OC     Document Type: Article

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