MicroRNA-650 expression is influenced by immunoglobulin gene rearrangement and affects the biology of chronic lymphocytic leukemia

Blood

Volumn 119, Issue 9, 2012, Pages 2110-2113

  Mraz, Marek ^a,b   Dolezalova, Dasa ^a   Plevova, Karla ^a,b   Kozubik, Katerina Stano ^a,b   Mayerova, Veronika ^a,b   Cerna, Katerina ^a,b   Musilova, Katerina ^a,b   Tichy, Boris ^a,b   Pavlova, Sarka ^a,b   Borsky, Marek ^b   Verner, Jan ^a,b   Doubek, Michael ^a,b   Brychtova, Yvona ^b   Trbusek, Martin ^a,b   Hampl, Ales ^a   Mayer, Jiri ^a,b   Pospisilova, Sarka ^a,b  

^a MASARYK UNIVERSITY   (Czech Republic)

^b UNIVERSITY HOSPITAL BRNO   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 1; IMMUNOGLOBULIN LAMBDA CHAIN; MICRORNA; MICRORNA 650; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; B LYMPHOCYTE; CELL FUNCTION; CELL SURVIVAL; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; DISEASE COURSE; FEMALE; GENE CONTROL; GENE EXPRESSION; GENE REARRANGEMENT; HUMAN; HUMAN CELL; IMMUNOGLOBULIN GENE; LYMPHOCYTE PROLIFERATION; MAJOR CLINICAL STUDY; MALE; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROGNOSIS; PROMOTER REGION;

EID: 84857724094     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-11-394874     Document Type: Article

References (25)

1. Stevenson FK, Krysov S, Davies AJ, Steele AJ, Packham G. B-cell receptor signaling in chronic lymphocytic leukemia. Blood. 2011;118(16):4313- 4320.
2. Vigorito E, Perks KL, Abreu-Goodger C, et al. microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells. Immunity. 2007;27(6):847-859. (Pubitemid 350258623)
3. Koralov SB, Muljo SA, Galler GR, et al. Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage. Cell. 2008;132(5):860- 874.
4. Xiao C, Rajewsky K. MicroRNA control in the immune system: basic principles. Cell. 2009;136(1): 26-36.
5. Calin GA, Croce CM. Chronic lymphocytic leukemia: interplay between noncoding RNAs and protein- coding genes. Blood. 2009;114(23):4761- 4770.
6. Calin GA, Ferracin M, Cimmino A, et al. A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N Engl J Med. 2005;353(17):1793-1801. (Pubitemid 41549891)
7. Mraz M, Malinova K, Kotaskova J, et al. miR-34a, miR-29c and miR-17-5p are downregulated in CLL patients with TP53 abnormalities. Leukemia. 2009;23(6):1159-1163.
8. Mraz M, Pospisilova S, Malinova K, Slapak I, Mayer J. MicroRNAs in chronic lymphocytic leukemia pathogenesis and disease subtypes. Leuk Lymphoma. 2009;50(3):506-509.
9. Vargova K, Curik N, Burda P, et al. MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia. Blood. 2011; 117(14):3816-3825.
10. Das S. Evolutionary origin and genomic organization of micro-RNA genes in immunoglobulin lambda variable region gene family. Mol Biol Evol. 2009;26(5):1179-1189.
11. Cummins JM, He Y, Leary RJ, et al. The colorectal microRNAome. Proc Natl Acad Sci U S A. 2006;103(10):3687-3692. (Pubitemid 43376616)
12. Feng L, Xie Y, Zhang H, Wu Y. Down-regulation of NDRG2 gene expression in human colorectal cancer involves promoter methylation and microRNA-650. Biochem Biophys Res Commun. 2011;406(4):534- 538.
13. Chien WW, Domenech C, Catallo R, et al. Cyclin-dependent kinase 1 expression is inhibited by p16(INK4a) at the post-transcriptional level through the microRNA pathway. Oncogene. 2011; 30(16):1880-1891.
14. Zhang X, Zhu W, Zhang J, et al. MicroRNA-650 targets ING4 to promote gastric cancer tumorigenicity. Biochem Biophys Res Commun. 2011; 395(2):275-280.
15. Chan E, Patel R, Nallur S, et al. MicroRNA signatures differentiate melanoma subtypes. Cell Cycle. 2011;10(11):1845-1852.
16. van Dongen JJ, Langerak AW, Brüggemann M, et al. Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia. 2003;17(12):2257-2317. (Pubitemid 38072572)
17. Mraz M, Malinova K, Mayer J, Pospisilova S. MicroRNA isolation and stability in stored RNA samples. Biochem Biophys Res Comm. 2009; 390(1):1-4.
18. Prestridge DS. Predicting Pol II promoter sequences using transcription factor binding sites. J Mol Biol. 1995;249(5):923-932.
19. Schug J. Using TESS to predict transcription factor binding sites in DNA sequence. Curr Protoc Bioinformatics. 2008;Chapter 2:Unit 2.6.
20. Rodriguez A, Griffiths-Jones S, Ashurst JL, Bradley A. Identification of mammalian microRNA host genes and transcription units. Genome Res. 2004;14(10A):1902-1910. (Pubitemid 39386503)
21. Stamatopoulos B, Meuleman N, Haibe-Kains B, et al. microRNA-29c and microRNA-223 downregulation has in vivo significance in chronic lymphocytic leukemia and improves disease risk stratification. Blood. 2009;113(21):5237- 5245.
22. Rossi S, Shimizu M, Barbarotto E, et al. microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival. Blood. 2010;116(6):945-952.
23. Huang dW, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc. 2009;4(1):44-57.
24. Hagman J, Lukin K. Early B-cell factor 'pioneers'the way for B-cell development. Trends Immunol. 2005;26(9):455-461. (Pubitemid 41139254)
25. Trbusek M, Smardova J, Malcikova J, et al. Missense mutations located in structural p53 DNA-binding motifs are associated with extremely poor survival in chronic lymphocytic leukemia. J Clin Oncol. 2011;29(19):2703-2708.