Health Effects of Mixed Fruit and Vegetable Concentrates: A Systematic Review of the Clinical Interventions

Journal of the American College of Nutrition

Volumn 30, Issue 5, 2011, Pages 285-294

  Esfahani, Amin ^a,b,d   Wong, Julia M W ^e,f   Truan, Jennifer ^a,b   Villa, Christopher R ^a   Mirrahimi, Arash ^a,b   Srichaikul, Korbua ^a,b   Kendall, Cyril W C ^a,b,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b ST MICHAEL'S HOSPITAL   (Canada)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

^d NEW YORK MEDICAL COLLEGE   (United States)

^e BOSTON CHILDREN S HOSPITAL   (United States)

^f HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Antioxidant; Concentrate; Fruit; Oxidative stress; Supplement; Vegetable

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; BETA CAROTENE; BIOLOGICAL MARKER; FOLIC ACID; HOMOCYSTEINE; ANTIOXIDANT; VITAMIN;

CARDIOVASCULAR RISK; DIET SUPPLEMENTATION; FOOD INTAKE; FRUIT; HUMAN; IMMUNITY; INFLAMMATION; LIPID OXIDATION; OXIDATION; REVIEW; VEGETABLE; VITAMIN BLOOD LEVEL; BLOOD; DIET; FEEDING BEHAVIOR; METABOLISM; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; RANDOMIZED CONTROLLED TRIAL (TOPIC);

ANTIOXIDANTS; ASCORBIC ACID; BETA CAROTENE; DIET; FOLIC ACID; FOOD HABITS; FRUIT; HOMOCYSTEINE; HUMANS; OXIDATION-REDUCTION; OXIDATIVE STRESS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; VEGETABLES; VITAMIN E; VITAMINS;

EID: 84857716991     PISSN: 07315724     EISSN: 15411087     Source Type: Journal    
DOI: 10.1080/07315724.2011.10719971     Document Type: Article

References (44)

1. Hung HC, Joshipura KJ, Jiang R, Hu FB, Hunter D, Smith-Warner SA, Colditz GA, Rosner B, Spiegelman D, Willett WC: Fruit and vegetable intake and risk of major chronic disease. J Natl Cancer Inst 96:1577-1584, 2004.
2. Block G, Patterson B, Subar A: Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence. Nutr Cancer 18:1-29, 1992.
3. Jenkins DJ, Kendall CW, Marchie A, Faulkner DA, Wong JM, de Souza R, Emam A, Parker TL, Vidgen E, Lapsley KG, Trautwein EA, Josse RG, Leiter LA, Connelly PW: Effects of a dietary portfolio of cholesterol-lowering foods vs lovastatin on serum lipids and C-reactive protein. JAMA 290:502-510, 2003.
4. Strain JJ, Elwood PC, Davis A, Kennedy O, Coulter J, Fehily A, Mulholland CW, Robson PJ, Thurnham DI: Frequency of fruit and vegetable consumption and blood antioxidants in the Caerphilly cohort of older men. Eur J Clin Nutr 54:828-833, 2000.
5. Brown L, Rosner B, Willett WW, Sacks FM: Cholesterol-lowering effects of dietary fiber: a meta-analysis. Am J Clin Nutr 69:30-42, 1999.
6. Jenkins DJ, Nguyen TH, Kendall CW, Faulkner DA, Bashyam B, Kim IJ, Ireland C, Patel D, Vidgen E, Josse AR, Sesso HD, Burton-Freeman B, Josse RG, Leiter LA, Singer W: The effect of strawberries in a cholesterol-lowering dietary portfolio. Metabolism 57:1636-1644, 2008.
7. Casagrande SS, Wang Y, Anderson C, Gary TL: Have Americans increased their fruit and vegetable intake? The trends between 1988 and 2002. Am J Prev Med 32:257-263, 2007.
8. Naska A, Vasdekis VG, Trichopoulou A, Friel S, Leonhauser IU, Moreiras O, Nelson M, Remaut AM, Schmitt A, Sekula W, Trygg KU, Zajkas G: Fruit and vegetable availability among ten European countries: how does it compare with the 'five-a-day' recommendation? DAFNE I and II projects of the European Commission. Br J Nutr 84:549-556, 2000.
9. Billson H, Pryer JA, Nichols R: Variation in fruit and vegetable consumption among adults in Britain. An analysis from the dietary and nutritional survey of British adults. Eur J Clin Nutr 53:946-952, 1999.
10. Liu RH: Health benefits of fruit and vegetables are from additive and synergistic combinations of phytochemicals. Am J Clin Nutr 78:517S-520S, 2003.
11. Oude Griep LM, Geleijnse JM, Kromhout D, Ocké MC, Verschuren WM. Raw and processed fruit and vegetable consumption and 10-year coronary heart disease incidence in a population-based cohort study in the Netherlands. PLoS One 5:e13609, 2010.
12. Wise J, Morin RJ, Sanderson R, Blum K: Changes in plasma carotenoid, alpha-tocopherol, and lipid peroxide levels in response to supplementation with concentrated fruit and vegetable extracts: a pilot study. Curr Ther Res Clin Exp 57:445-461, 1996.
13. Inserra PF, Jiang S, Solkoff D, Lee J, Zhang Z, Xu M, Hesslink R Jr, Wise J, Watson RR: Immune function in elderly smokers and nonsmokers improves during supplementation with fruit and vegetable extracts. Int Med 2:3-10, 1999.
14. Smith MJ, Inserra PF, Watson RR, Wise J, O'Neil KL: Supplementation with fruit and vegetable extracts may decrease DNA damage in the peripheral lymphocytes of an elderly population. Nutr Res 19:1507-1518, 1999.
15. Plotnick GD, Corretti MC, Vogel RA, Hesslink R Jr, Wise JA: Effect of supplemental phytonutrients on impairment of the flowmediated brachial artery vasoactivity after a single high-fat meal. J Am Coll Cardiol 41:1744-1749, 2003.
16. Kiefer I, Prock P, Lawrence C, Wise J, Bieger W, Bayer P, Rathmanner T, Kunze M, Rieder A: Supplementation with mixed fruit and vegetable juice concentrates increased serum antioxidants and folate in healthy adults. J Am Coll Nutr 23:205-211, 2004.
17. Kawashima A, Madarame T, Koike H, Komatsu Y, Wise JA: Four week supplementation with mixed fruit and vegetable juice concentrates increased protective serum antioxidants and folate and decreased plasma homocysteine in Japanese subjects. Asia Pac J Clin Nutr 16:411-421, 2007.
18. Wise JA, Kaats GR, Preuss HG, Morin RJ: Beta-carotene and alpha-tocopherol in healthy overweight adults; depletion kinetics are correlated with adiposity. Int J Food Sci Nutr 60(suppl 3):65-75, 2009.
19. Leeds AR, Ferris EAE, Staley R, Ayesh R, Ross F: Availability of micronutrients from dried, encapsulated fruit and vegetable preparations: a study in healthy volunteers. J Hum Nutr Dietet 13:21-27, 2000.
20. Panunzio MF, Pisano A, Antoniciello A, Di Martino V, Frisoli L, Cipriani V, Mongelli MA, Bronzetti G: Supplementation with fruit and vegetable concentrate decreases plasma homocysteine levels in a dietary controlled trial. Nutr Res 23:1221-1228, 2003.
21. Bloomer RJ, Goldfarb AH, McKenzie MJ: Oxidative stress response to aerobic exercise: comparison of antioxidant supplements. Med Sci Sports Exerc 38:1098-1105, 2006.
22. Goldfarb AH, McKenzie MJ, Bloomer RJ: Gender comparisons of exercise-induced oxidative stress: influence of antioxidant supplementation. Appl Physiol Nutr Metab 32:1124-1131, 2007.
23. Arendt BM, Boetzer AM, Lemoch H, Winkler P, Rockstroh JK, Berthold HK, Spengler U, Goerlich R: Plasma antioxidant capacity of HIV-seropositive and healthy subjects during longterm ingestion of fruit juices or a fruit-vegetable-concentrate containing antioxidant polyphenols. Eur J Clin Nutr 55:786-792, 2001.
24. Winkler P, Ellinger S, Boetzer AM, Arendt BM, Berthold HK, Rockstroh JK, Spengler U, Goerlich R: Lymphocyte proliferation and apoptosis in HIV-seropositive and healthy subjects during long-term ingestion of fruit juices or a fruit-vegetable-concentrate rich in polyphenols and antioxidant vitamins. Eur J Clin Nutr 58:317-325, 2004.
25. Samman S, Sivarajah G, Man JC, Ahmad ZI, Petocz P, Caterson ID: A mixed fruit and vegetable concentrate increases plasma antioxidant vitamins and folate and lowers plasma homocysteine in men. J Nutr 133:2188-2193, 2003.
26. Nantz MP, Rowe CA, Nieves C Jr, Percival SS: Immunity and antioxidant capacity in humans is enhanced by consumption of a dried, encapsulated fruit and vegetable juice concentrate. J Nutr 136:2606-2610, 2006.
27. Houston MC, Cooil B, Olafsson BJ, Raggi P: Juice powder concentrate and systemic blood pressure, progression of coronary artery calcium and antioxidant status in hypertensive subjects: A pilot study. Evid Based Complement Alternat Med 4:455-462, 2007.
28. Bamonti F, Novembrino C, Ippolito S, Soresi E, Ciani A, Lonati S, Scurati-Manzoni E, Cighetti G: Increased free malondialdehyde concentrations in smokers normalise with a mixed fruit and vegetable juice concentrate: a pilot study. Clin Chem Lab Med 44:391-395, 2006.
29. Lamprecht M, Oettl K, Schwaberger G, Hofmann P, Greilberger JF: Several indicators of oxidative stress, immunity, and illness improved in trained men consuming an encapsulated juice powder concentrate for 28 weeks. J Nutr 137:2737-2741, 2007.
30. Lamprecht M, Oettl K, Schwaberger G, Hofmann P, Greilberger JF: Protein modification responds to exercise intensity and antioxidant supplementation. Med Sci Sports Exerc 41:155-163, 2009.
31. Jin Y, Cui X, Singh U, Chumanevich A, Harmon B, Cavicchia P, Hofseth A, Kotakadi V, Stroud B, Volate S, Hurley T, Herbert J, Hofseth L: Systematic inflammatory load in humans is suppressed by consumption of two formulations of dried, encapsulated juice concentrate. Mol Nutr Food Res 54:1506-1514, 2010.
32. Roll S, Nocon M, Willich SN: Reduction of common cold symptoms by encapsulated juice powder concentrate of fruits and vegetables: a randomised, double-blind, placebo-controlled trial. Br J Nutr 105:118-122, 2011.
33. Goldfarb AH, Garten RS, Cho C, Chee PD, Chambers LA: Effects of a fruit/berry/vegetable supplement on muscle function and oxidative stress. Med Sci Sports Exerc, 43:501-508, 2011.
34. Halliwell B: Oxidative stress and cancer: have we moved forward? Biochem J 401:1-11, 2007.
35. Higgins JP, Green S: ''Cochrane Handbook for Systematic Reviews of Interventions,'' version 5.0.0 updated. [Location]: The Cochrane Collaboration, 2008.
36. Chevion M, Berenshtein E, Stadtman ER: Human studies related to protein oxidation: protein carbonyl content as a marker of damage. Free Radic Res 33(suppl):S99-108, 2000.
37. Dalle-Donne I, Rossi R, Giustarini D, Milzani A, Colombo R: Protein carbonyl groups as biomarkers of oxidative stress. Clin Chim Acta 329:23-38, 2003.
38. Lee SH, Blair IA: Oxidative DNA damage and cardiovascular disease. Trends Cardiovasc Med 11:148-155, 2001.
39. Herrmann W: The importance of hyperhomocysteinemia as a risk factor for diseases: an overview. Clin Chem Lab Med 39:666-674, 2001.
40. Herrmann W, Knapp JP: Hyperhomocysteinemia: a new risk factor for degenerative diseases. Clin Lab 48:471-481, 2002.
41. Malinow MR: Plasma concentrations of total homocysteine predict mortality risk. Am J Clin Nutr 74:3, 2001.
42. Marti-Carvajal AJ, Sola I, Lathyris D, Salanti G: Homocysteine lowering interventions for preventing cardiovascular events. Cochrane Database Syst Rev CD006612, 2009.
43. Helfand M, Buckley DI, Freeman M, Fu R, Rogers K, Fleming C, Humphrey LL: Emerging risk factors for coronary heart disease: a summary of systematic reviews conducted for the U.S. Preventive Services Task Force. Ann Intern Med 151:496-507, 2009.
44. Dary O: Nutritional interpretation of folic acid interventions. Nutr Rev 67:235-244, 2009.