Translatability scoring in drug development: Eight case studies

Journal of Translational Medicine

Volumn 10, Issue 1, 2012, Pages

  Wendler, Alexandra ^a   Wehling, Martin ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Dabigatran; Drug development; Gefitinib; Ipilimumab; Latrepirdine; Semagacestat; Translatability score; Translational medicine; Vilazodone

Indexed keywords

ACETYLSALICYLIC ACID; ANTIVITAMIN K; DABIGATRAN; DABIGATRAN ETEXILATE; DACARBAZINE; DIMEBON; DOCETAXEL; EPIDERMAL GROWTH FACTOR RECEPTOR; GEFITINIB; INTERLEUKIN 2; IPILIMUMAB; PHENPROCOUMON; PLACEBO; PLATINUM COMPLEX; SEMAGACESTAT; SEROTONIN 1A ANTAGONIST; SEROTONIN UPTAKE INHIBITOR; TORCETRAPIB; VARENICLINE; VILAZODONE; WARFARIN; BIOLOGICAL MARKER; DRUG;

ALZHEIMER DISEASE; ARTICLE; CARDIOVASCULAR DISEASE; CASE STUDY; CHEMOPROPHYLAXIS; COLITIS; DIARRHEA; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG MEGADOSE; DRUG POTENTIATION; DRUG RESEARCH; DRUG RESPONSE; DRUG SAFETY; EYE TOXICITY; GENE MUTATION; GENETIC MARKER; HEART ATRIUM FIBRILLATION; HUMAN; HYPERCHOLESTEROLEMIA; HYPOPHYSITIS; IC 50; IMMUNOPATHOLOGY; LUNG NON SMALL CELL CANCER; MAJOR DEPRESSION; MELANOMA; NONHUMAN; PANCREATITIS; PATIENT COMPLIANCE; PERSONALIZED MEDICINE; PHARMACOGENETICS; PREDICTION; RETROSPECTIVE STUDY; SCORING SYSTEM; STROKE; TOBACCO DEPENDENCE; TRANSLATIONAL RESEARCH; UNSPECIFIED SIDE EFFECT; VENOUS THROMBOEMBOLISM; ANIMAL; CLINICAL TRIAL (TOPIC); DISEASE MODEL; DRUG DEVELOPMENT;

ANIMALS; BIOLOGICAL MARKERS; CLINICAL TRIALS AS TOPIC; DISEASE MODELS, ANIMAL; DRUG DISCOVERY; HUMANS; INDIVIDUALIZED MEDICINE; PHARMACEUTICAL PREPARATIONS; TRANSLATIONAL MEDICAL RESEARCH;

EID: 84857708998     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-10-39     Document Type: Article

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