Lichen secondary metabolites are responsible for induction of apoptosis in HT-29 and A2780 human cancer cell lines

Toxicology in Vitro

Volumn 26, Issue 3, 2012, Pages 462-468

  Backorova M ^a   Jendzelovsky R ^a   Kello, M ^a   Backor M ^a   Mikes J ^a   Fedorocko P ^a  

^a P J AFÁRIK UNIVERSITY   (Slovakia)

Author keywords

Atranorin; Gyrophoric acid; Lichens; Oxidative stress; Parietin; Usnic acid

Indexed keywords

ANTINEOPLASTIC AGENT; ATRANORIN; CASPASE 3; GYROPHORIC ACID; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLSERINE; PHYSCION; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN P53; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; USNIC ACID;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LICHENS; LONG TERM EXPOSURE; METABOLITE; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; PHYTOCHEMISTRY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASE 3; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HT29 CELLS; HUMANS; LICHENS; MEMBRANE POTENTIAL, MITOCHONDRIAL; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES;

EID: 84857685183     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2012.01.017     Document Type: Article

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