Solid pattern yolk sac tumor: A morphologic and immunohistochemical study of 52 cases

American Journal of Surgical Pathology

Volumn 36, Issue 3, 2012, Pages 360-367

  Kao, Chia Sui ^a   Idrees, Muhammad T ^a   Young, Robert H ^b   Ulbright, Thomas M ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

mediastinum; solid pattern; testis; yolk sac tumor

Indexed keywords

TUMOR MARKER;

ADOLESCENT; ADULT; ARTICLE; CHEMISTRY; DIAGNOSTIC ERROR; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; MEDIASTINUM TUMOR; METASTASIS; MIDDLE AGED; PATHOLOGY; PREDICTIVE VALUE; SEMINOMA; TESTIS TUMOR; YOLK SAC TUMOR;

ADOLESCENT; ADULT; DIAGNOSTIC ERRORS; ENDODERMAL SINUS TUMOR; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MEDIASTINAL NEOPLASMS; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; SEMINOMA; TESTICULAR NEOPLASMS; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 84857648878     PISSN: 01475185     EISSN: 15320979     Source Type: Journal    
DOI: 10.1097/PAS.0b013e31823c510b     Document Type: Article

References (50)

1. Albers P, Miller GA, Orazi A, et al. Immunohistochemical assessment of tumor proliferation and volume of embryonal carcinoma identify patients with clinical stage A nonseminomatous testicular germ cell tumor at low risk for occult metastasis. Cancer. 1995;75:844-850.
2. Bosl GJ, Motzer RJ. Testicular germ-cell cancer. New Engl J Med. 1997;337:242-253.
3. Cao D, Li J, Guo CC, et al. SALL4 is a novel diagnostic marker for testicular germ cell tumors. Am J Surg Pathol. 2009;33:1065-1077.
4. Clement PB, Young RH. Pathology of extragonadal yolk sac tumors. In: Nogales FF, ed. The Human Yolk Sac and Yolk Sac Tumors. Berlin: Springer-Verlag; 1993:285-308.
5. Copeland LJ, Sneige N, Ordonez NG, et al. Endodermal sinus tumor of the vagina and cervix. Cancer. 1985;55:2558-2565.
6. de Riese WT, Albers P, Walker EB, et al. Predictive parameters of biologic behavior of early stage nonseminomatous testicular germ cell tumors. Cancer. 1994;74:1335-1341.
7. Dehner LP. Gonadal and extragonadal germ cell neoplasia of childhood. Hum Pathol. 1983;14:493-511.
8. Eglen DE, Ulbright TM. The differential diagnosis of yolk sac tumor and seminoma: usefulness of cytokeratin, alpha-fetoprotein, and alpha-1-antitrypsin immunoperoxidase reactions. Am J Clin Pathol. 1987;88:328-332.
9. Friedman NB, Moore RA. Tumors of the testis: a report on 922 cases. Milit Surgeon. 1946;99:573-593.
10. Gonzalez-Crussi F. The human yolk sac and yolk sac (endodermal sinus) tumors. A review. Perspect Pediatr Pathol. 1979;5:179-215.
11. Harms D, Janig U. Germ cell tumours of childhood: report of 170 cases including 59 pure and partial yolk-sac tumours. Virchows Arch [A]. 1986;409:223-229.
12. Hawkins EP, Finegold MJ, Hawkins HK, et al. Nongerminomatous malignant germ cell tumors in children: a review of 89 cases from the Pediatric Oncology Group, 1971 to 1984. Cancer. 1986;58:2579-2584.
13. Huntington RW Jr. Morgenstern L, Sargent JA, et al. Germinal tumors exhibiting the endodermal sinus pattern of Teilum in young children. Cancer. 1963;16:34-47.
14. Izquierdo MA, Van der Valk P, Van Ark-Otte J, et al. Differential expression of the c-kit proto-oncogene in germ cell tumours. J Pathol. 1995;177:253-258.
15. Jacobsen GK. Histogenetic considerations concerning germ cell tumours. Morphological and immunohistochemical comparative investigation of the human embryo and testicular germ cell tumours. Virchows Arch [A]. 1986;408:509-525.
16. Jacobsen GK, von der Maase H, Specht L, et al. Histopathological features in stage I seminoma treated with orchidectomy only. J Urol Pathol. 1995;3:85-94.
17. Jones TD, Ulbright TM, Eble JN, et al. OCT4 staining in testicular tumors: a sensitive and specific marker for seminoma and embryonal carcinoma. Am J Surg Pathol. 2004;28:935-940.
18. Kozakewich HP, Rice E, Vawter GF, et al. Yolk sac tumor of the testis in children. Lab Invest. 1984;50:32A.
19. Kurman RJ, Norris HJ. Endodermal sinus tumor of the ovary: clinical and pathologic analysis of 71 cases. Cancer. 1976;38:2404-2419.
20. Lau SK, Weiss LM, Chu PG. D2-40 immunohistochemistry in the differential diagnosis of seminoma and embryonal carcinoma: a comparative immunohistochemical study with KIT (CD117) and CD30. Mod Pathol. 2007;20:320-325.
21. Leroy X, Augusto D, Leteurtre E, et al. CD30 and CD117 (c-kit) used in combination are useful for distinguishing embryonal carcinoma from seminoma. J Histochem Cytochem. 2002;50:283-285.
22. Looijenga LH, Stoop H, de Leeuw HP, et al. POU5F1 (OCT3/4) identifies cells with pluripotent potential in human germ cell tumors. Cancer Res. 2003;63:2244-2250.
23. Morris HH, La VC, Draper GJ. Endodermal sinus tumor and embryonal carcinoma of the ovary in children. Gynecol Oncol. 1985;21:7-17.
24. Neubecker RD, Breen JL. Embryonal carcinoma of the ovary. Cancer. 1962;15:546-556.
25. Niehans GA, Manivel JC, Copland GT, et al. Immunohistochemistry of germ cell and trophoblastic neoplasms. Cancer. 1988;62:1113-1123.
26. Nogales FF, Beltran E, Pavcovich M. Pathology of ovarian yolk sac tumors. In: Nogales FF, ed. The Human Yolk Sac and Yolk Sac Tumors. Berlin: Springer-Verlag; 1993:228-244.
27. Ota S, Hishinuma M, Yamauchi N, et al. Oncofetal protein glypican-3 in testicular germ-cell tumor. Virchows Arch. 2006;449:308-314.
28. Prat J, Bhan AK, Dickersin GR, et al. Hepatoid yolk sac tumor of the ovary (endodermal sinus tumor with hepatoid differentiation): a light microscopic, ultrastructural and immunohistochemical study of seven cases. Cancer. 1982;50:2355-2368.
29. Putti TC, To KF, Hsu HC, et al. Expression of epidermal growth factor receptor in head and neck cancers correlates with clinical progression: a multicentre immunohistochemical study in the Asia-Pacific region. Histopathology. 2002;41:144-151.
30. Remmele W, Stegner HE. Recommendation for uniform definition of an immunoreactive score (IRS) for immunohistochemical estrogen receptor detection (ER-ICA) in breast cancer tissue (German). Pathologe. 1987;8:138-140.
31. Scully RE, Young RH, Clement PB. Tumors of the Ovary, Maldeveloped Gonads, Fallopian Tube and Broad Ligament Atlas of Tumor Pathology. Washington, DC: Armed Forces Institute of Pathology; 1998:246-254.
32. Sung MT, MacLennan GT, Cheng L. Retroperitoneal seminoma in limited biopsies: morphologic criteria and immunohistochemical findings in 30 cases. Am J Surg Pathol. 2006;30:766-773.
33. Sung MT, MacLennan GT, Lopez-Beltran A, et al. Primary mediastinal seminoma: a comprehensive assessment integrated with histology, immunohistochemistry, and fluorescence in situ hybridization for chromosome 12p abnormalities in 23 cases. Am J Surg Pathol. 2008;32:146-155.
34. Talerman A. Germ cell tumors. In: Talerman A, Roth LM, eds. Pathology of the Testis and its Adnexa. New York: Churchill Livingstone; 1986:29-65.
35. Talerman A, Vang R. Germ cell tumors of the ovary. In: Kurman RJ, Ellenson LH, Ronnett BM, eds. Blaustein's Pathology of the Female Genital Tract. New York: Springer; 2011:;847-907.
36. Teilum G. Homologous tumors in the ovary and testis. Contributions to classification of the gonadal tumors. Acta Obstet Gynecol. 1944;24:480-503.
37. Teilum G. Gonocytoma: homologous ovarian and testicular tumors I: with discussion of "mesonephroma ovarii" (Schiller: Am J Cancer 1939). Acta Pathol Microbiol Scand. 1946;23:242-251.
38. Teilum G. "Mesonephroma ovarii" (Schiller): an extra-embryonic mesoblastoma of germ cell origin in the ovary and the testis. Acta Pathol Microbiol Scand. 1950;27:249-261.
39. Teilum G. Endodermal sinus tumors of the ovary and testis: comparative morphogenesis of the so-called mesonephroma ovarii (Schiller) and extraembryonic (yolk sac-allantoic) structures of the rat's placenta. Cancer. 1959;12:1092-1105.
40. Teilum G. Special Tumors of Ovary and Testis and Related Extragonadal Lesions. Philadelphia: J. B. Lippincott; 1976:44-47.
41. Ulbright TM. Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues. Mod Pathol. 2005;18(Suppl 2): S61-S79.
42. Ulbright TM, Amin MB, Young RH. Atlas of Tumor Pathology: Tumors of the Testis, Adenexa, Spermatic Cord and Scrotum Third Series. Washington, DC: Armed Forces Institute of Pathology; 1999:61-77.
43. Ulbright TM, Roth LM, Brodhecker CA. Yolk sac differentiation in germ cell tumors. A morphologic study of 50 cases with emphasis on hepatic, enteric, and parietal yolk sac features. Am J Surg Pathol. 1986;10:151-164.
44. Ulbright TM, Young RH. Seminoma with tubular, microcystic, and related patterns: a study of 28 cases of unusual morphologic variants that often cause confusion with yolk sac tumor. Am J Surg Pathol. 2005;29:500-505.
45. Woodward PJ, Mostofi FK, Talerman A, et al. Germ cell tumours. In: Eble JN, Sauter G, Epstein JI, et al, eds. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. Lyon: IARC Press; 2004:221-249.
46. Young PG, Mount BM, Foote FW Jr., et al. Embryonal adenocarcinoma in the prepubertal testis. A clinicopathologic study of 18 cases. Cancer. 1970;26:1065-1075.
47. Young RH, Scully RE. Testicular Tumors. Chicago: ASCP Press; 1990:10-24.
48. Yu H, Pinkus GS, Hornick JL. Diffuse membranous immunoreactivity for podoplanin (D2-40) distinguishes primary and metastatic seminomas from other germ cell tumors and metastatic neoplasms. Am J Clin Pathol. 2007;128:767-775.
49. Zynger DL, Dimov ND, Luan C, et al. Glypican 3: a novel marker in testicular germ cell tumors. Am J Surg Pathol. 2006;30:1570-1575.
50. Zynger DL, McCallum JC, Luan C, et al. Glypican 3 has a higher sensitivity than alpha-fetoprotein for testicular and ovarian yolk sac tumour: immunohistochemical investigation with analysis of histological growth patterns. Histopathology. 2010;56:750-757.