Protein profiles in human ovarian cancer cell lines correspond to their metabolic activity and to metabolic profiles of respective tumor xenografts

FEBS Journal

Volumn 279, Issue 5, 2012, Pages 882-891

  Fabian, Christian ^a   Koetz, Lisa ^a,c   Favaro, Elena ^b,d   Indraccolo, Stefano ^b   Mueller Klieser, Wolfgang ^a   Sattler, Ulrike G A ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b VENETO INSTITUTE OF ONCOLOGY IOV IRCCS   (Italy)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

extracellular flux analysis; induced metabolic bioluminescence imaging; lactate; ovarian cancer; tumor cell metabolism

Indexed keywords

GLUCOSE TRANSPORTER 1; HEXOKINASE; HEXOKINASE ISOENZYME; MONOCARBOXYLATE TRANSPORTER 4; PYRUVATE DEHYDROGENASE; PYRUVATE DEHYDROGENASE E1 BETA SUBUNIT; PYRUVATE DEHYDROGENASE KINASE; PYRUVATE DEHYDROGENASE KINASE 1; PYRUVATE KINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOENERGY; CANCER CELL CULTURE; CELL ENERGY; CELL METABOLISM; CONTROLLED STUDY; FEMALE; GLUCOSE METABOLISM; GLYCOLYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; OVARY CANCER; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SCID MOUSE; TUMOR XENOGRAFT;

ANIMALS; ENERGY METABOLISM; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GLYCOLYSIS; HUMANS; METABOLOME; MICE; MICE, SCID; OVARIAN NEOPLASMS; OXYGEN CONSUMPTION; PROTEINS; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

MUS;

EID: 84857647906     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2012.08479.x     Document Type: Article

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