Local antibiotic delivery with demineralized bone matrix

Cell and Tissue Banking

Volumn 13, Issue 1, 2012, Pages 119-127

  Lewis, Christine S ^a   Supronowicz, Peter R ^a   Zhukauskas, Rasa M ^a   Gill, Elise ^a   Cobb, Ronald R ^a  

^a Research and Development Group   (United States)

Author keywords

Antibiotic; Demineralized bone matrix; Osteomyelitis; Staphylococcus aureus

Indexed keywords

ALKALINE PHOSPHATASE; ANTIINFECTIVE AGENT; GENTAMICIN;

ANIMAL; ARTICLE; BONE DEVELOPMENT; BONE MATRIX; BONE REGENERATION; CELL ADHESION; CELL PROLIFERATION; CYTOLOGY; DRUG DELIVERY SYSTEM; DRUG EFFECT; ENZYMOLOGY; HISTOLOGY; HUMAN; KINETICS; METABOLISM; METHODOLOGY; MICROBIOLOGICAL EXAMINATION; OSTEOBLAST; RAT; STAPHYLOCOCCUS AUREUS;

ALKALINE PHOSPHATASE; ANIMALS; ANTI-BACTERIAL AGENTS; BONE DEMINERALIZATION TECHNIQUE; BONE MATRIX; CELL ADHESION; CELL PROLIFERATION; DRUG DELIVERY SYSTEMS; GENTAMICINS; HUMANS; KINETICS; MICROBIAL SENSITIVITY TESTS; OSSEOINTEGRATION; OSTEOBLASTS; OSTEOGENESIS; RATS; STAPHYLOCOCCUS AUREUS;

EID: 84857647466     PISSN: 13899333     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10561-010-9236-y     Document Type: Article

References (45)

1. M Alexeeff N Mahomed E Morsi D Garbuz A Gross 1996 Structural allograft in two-stage revisions for failed septic hip arthroplasty J Bone Joint Surg Br 78 213 216 8666627 1:STN:280:DyaK283gvFCnuw%3D%3D (Pubitemid 26096994)
2. P Anguita-Alonso MS Rouse KE Piper DJ Jacofsky DR Osmon R Patel 2006 Comparative study of antimicrobial release kinetics from polymethylmethacrylate Clin Orthop Relat Res 445 239 244 16474225 (Pubitemid 44341351)
3. L Bunetel A Segui M Cormier E Percheron F Langlais 1989 Release of gentamicin from acrylic bone cement Clin Pharmacokinet 17 291 297 2591139 1:CAS:528:DyaK3cXkt1Gjsw%3D%3D (Pubitemid 19263892)
4. M Buttaro R Valentini F Piccaluga 2004 Persistent infection associated with residual cement after resection arthroplasty of the hip Acta Orthop Scand 75 427 429 15370586 (Pubitemid 39179528)
5. Chesmel KD, Branger J, Wertheim H, Scarborough N (1998) Healing response to various forms of human demineralized bone matrix in athymic rat cranial defects. J Oral Maxillofac Surg 56:857-863 (discussion 864-865)
6. CN Cornell 1999 Osteoconductive materials and their role as substitutes for autogenous bone grafts Orthop Clin North Am 30 591 598 10471764 1:STN:280:DyaK1MvgtlWmsA%3D%3D (Pubitemid 29471301)
7. JW Costerton PS Stewart EP Greenberg 1999 Bacterial biofilms: a common cause of persistent infections Science 284 1318 1322 10334980 1:CAS:528:DyaK1MXjs1Squ78%3D (Pubitemid 29289651)
8. Deirmengian C, Greenbaum J, Stern J, Braffman M, Lotke PA, Booth RE Jr., Lonner JH (2003) Open debridement of acute gram-positive infections after total knee arthroplasty. Clin Orthop Relat Res 416:129-134 (Pubitemid 37413630)
9. C Delloye P De Nayer N Allington E Munting L Coutelier A Vincent 1988 Massive bone allografts in large skeletal defects after tumor surgery: a clinical and microradiographic evaluation Arch Orthop Trauma Surg 107 31 41 3278701 1:STN:280:DyaL1c7kvFalsw%3D%3D (Pubitemid 18005680)
10. Dick HM, Strauch RJ (1994) Infection of massive bone allografts. Clin Orthop Relat Res 306:46-53 (Pubitemid 24324933)
11. FR Dimaio JJ O'Halloran JM Quale 1994 In vitro elution of ciprofloxacin from polymethylmethacrylate cement beads J Orthop Res 12 79 82 8113945 1:CAS:528:DyaK2cXktFOrsLs%3D (Pubitemid 24070791)
12. Edwards JT, Diegmann MH, Scarborough NL (1998) Osteoinduction of human demineralized bone: characterization in a rat model. Clin Orthop Relat Res 357:219-228 (Pubitemid 29022452)
13. P Gilbert J Das I Foley 1997 Biofilm susceptibility to antimicrobials Adv Dent Res 11 160 167 9524452 1:STN:280:DyaK1c7osFWgug%3D%3D
14. J Glowacki LB Kaban JE Murray J Folkman JB Mulliken 1981 Application of the biological principle of induced osteogenesis for craniofacial defects Lancet 1 959 962 6112384 1:STN:280:DyaL3M7ps1aitA%3D%3D (Pubitemid 11154966)
15. Hanssen AD (2005) Local antibiotic delivery vehicles in the treatment of musculoskeletal infection. Clin Orthop Relat Res 437:91-96 (Pubitemid 41099072)
16. Hanssen AD, Osmon DR, Patel R (2005) Local antibiotic delivery systems: where are we and where are we going? Clin Orthop Relat Res 437:111-114 (Pubitemid 41099075)
17. SL Henry KP Galloway 1995 Local antibacterial therapy for the management of orthopaedic infections. Pharmacokinetic considerations Clin Pharmacokinet 29 36 45 7586897 1:STN:280:DyaK28%2FmsFygsw%3D%3D
18. KE Kado LA Gambetta MD Perlman 1996 Uses of Grafton for reconstructive foot and ankle surgery J Foot Ankle Surg 35 59 66 8834189 1:STN:280: DyaK28vjtFWjtQ%3D%3D (Pubitemid 26066706)
19. Katz JM, Diegl EC, Nataraj C (2006) Time course of DBM induced intermuscular endochondral ossification (abs 912)
20. PD Levin 1975 The effectiveness of various antibiotics in methyl methacrylate J Bone Joint Surg Br 57 234 237 167026 1:STN:280: DyaE2M7ovFGksA%3D%3D
21. Lewis CS, Katz JM, Baker MI, Supronowicz PR, Gill E, Cobb RR (2010) Local antibiotic delivery with cancellous chips and cubes. J Biomater Appl (in publication)
22. D Logeart-Avramoglou F Anagnostou R Bizios H Petite 2005 Engineering bone: challenges and obstacles J Cell Mol Med 9 72 84 15784166 1:CAS:528:DC%2BD2MXlt1eqtLs%3D
23. M Lynch MP Esser P Shelley BM Wroblewski 1987 Deep infection in Charnley low-friction arthroplasty. Comparison of plain and gentamicin-loaded cement J Bone Joint Surg Br 69 355 360 3584184 1:STN:280:DyaL2s3it1CksA%3D%3D (Pubitemid 17098464)
24. W McGann HJ Mankin WH Harris 1986 Massive allografting for severe failed total hip replacement J Bone Joint Surg Am 68 4 12 3510213 1:STN:280: DyaL28%2Fos1Smsw%3D%3D (Pubitemid 16184120)
25. McLaren AC (2004) Alternative materials to acrylic bone cement for delivery of depot antibiotics in orthopaedic infections. Clin Orthop Relat Res 427:101-106 (Pubitemid 39362838)
26. T Miclau LE Dahners RW Lindsey 1993 In vitro pharmacokinetics of antibiotic release from locally implantable materials J Orthop Res 11 627 632 8410461 1:CAS:528:DyaK2cXhslehur0%3D (Pubitemid 23320910)
27. Nelson CL (2004) The current status of material used for depot delivery of drugs. Clin Orthop Relat Res 427:72-78 (Pubitemid 39362834)
28. MW Nijhof HP Stallmann HC Vogley A Fleer LM Schouls WJ Dhert AJ Verbout 2000 Prevention of infection with tobramycin-containing bone cement or systemic cefazolin in an animal model J Biomed Mater Res 52 709 715 11033554 1:CAS:528:DC%2BD3cXnt1Clurw%3D
29. Perry AC, Rouse MS, Khaliq Y, Piper KE, Hanssen AD, Osmon DR, Steckelberg JM, Patel R (2002) Antimicrobial release kinetics from polymethylmethacrylate in a novel continuous flow chamber. Clin Orthop Relat Res 403:49-53 (Pubitemid 35168355)
30. WH Petri III SJ Schaberg 1984 The effects of antibiotic-supplemented bone allografts on contaminated, partially avulsive fractures of the canine ulna J Oral Maxillofac Surg 42 699 704 6436455 (Pubitemid 15215825)
31. JS Price AF Tencer DM Arm GA Bohach 1996 Controlled release of antibiotics from coated orthopedic implants J Biomed Mater Res 30 281 286 8698690 1:CAS:528:DyaK28XhtlWru7c%3D (Pubitemid 26071916)
32. DA Puleo LA Holleran RH Doremus R Bizios 1991 Osteoblast responses to orthopedic implant materials in vitro J Biomed Mater Res 25 711 723 1874756 1:CAS:528:DyaK3MXlsVaiu7w%3D
33. Sassard WR, Eidman DK, Gray PM, Block JE, Russo R, Russell JL, Taboada EM (2000) Augmenting local bone with Grafton demineralized bone matrix for posterolateral lumbar spine fusion: avoiding second site autologous bone harvest. Orthopedics 23:1059-1064 (discussion 1064-1065)
34. CM Stevens KD Tetsworth JH Calhoun JT Mader 2005 An articulated antibiotic spacer used for infected total knee arthroplasty: a comparative in vitro elution study of Simplex and Palacos bone cements J Orthop Res 23 27 33 15607871 1:CAS:528:DC%2BD2cXhtVylu7fF (Pubitemid 40045073)
35. M Stigter J Bezemer K De Groot P Layrolle 2004 Incorporation of different antibiotics into carbonated hydroxyapatite coatings on titanium implants, release and antibiotic efficacy J Control Release 99 127 137 15342186 1:CAS:528:DC%2BD2cXnt1Kjt7s%3D (Pubitemid 39165739)
36. JJ Tiedeman KL Garvin TA Kile JF Connolly 1995 The role of a composite, demineralized bone matrix and bone marrow in the treatment of osseous defects Orthopedics 18 1153 1158 8749293 1:STN:280:DyaK28zmtlamtA%3D%3D
37. MR Urist 1965 Bone: formation by autoinduction Science 150 893 899 5319761 1:STN:280:DyaF28%2FhvFekuw%3D%3D
38. MR Urist TA Dowell 1968 Inductive substratum for osteogenesis in pellets of particulate bone matrix Clin Orthop Relat Res 61 61 78 4236465 1:STN:280:DyaF1M%2Fos1OrsQ%3D%3D
39. G Waertel 1996 The role of antibiotic-loaded cement in the treatment of an infection after a hip replacement J Bone Joint Surg Am 78 472 473 8613456 1:STN:280:DyaK283gtlOktg%3D%3D
40. BJ Waldman E Hostin MA Mont DS Hungerford 2000 Infected total knee arthroplasty treated by arthroscopic irrigation and debridement J Arthroplasty 15 430 436 10884201 1:STN:280:DC%2BD3M%2Fks1CitQ%3D%3D (Pubitemid 30413882)
41. H Winkler O Janata C Berger W Wein A Georgopoulos 2000 In vitro release of vancomycin and tobramycin from impregnated human and bovine bone grafts J Antimicrob Chemother 46 423 428 10980169 1:CAS:528:DC%2BD3cXmvV2kt7k%3D
42. E Wisto L Persen K Loseth K Bergh 1999 Adsorption and release of antibiotics from morselized cancellous bone. In vitro studies of 8 antibiotics Acta Orthop Scand 70 298 304 (Pubitemid 29327026)
43. E Wisto L Persen P Benum K Bergh 2002 Release of netilmicin and vancomycin from cancellous bone Acta Orthop Scand 73 199 205 (Pubitemid 34557062)
44. E Witso L Persen K Loseth P Benum K Bergh 2000 Cancellous bone as an antibiotic carrier Acta Orthop Scand 71 80 84 10743999 1:STN:280: DC%2BD3c3gsFyltA%3D%3D (Pubitemid 30150562)
45. Zalavras CG, Patzakis MJ, Holtom P (2004) Local antibiotic therapy in the treatment of open fractures and osteomyelitis. Clin Orthop Relat Res 427:86-93 (Pubitemid 39362836)