Adsorption and release of antibiotics from morselized cancellous bone

Acta Orthopaedica Scandinavica

Volumn 70, Issue 3, 1999, Pages 298-304

  Witsø, Eivind ^a   Persen, Leif ^a   Løseth, Kirsti ^a   Bergh, Kåre ^a  

^a TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CEFALOTIN; CIPROFLOXACIN; CLINDAMYCIN; DICLOXACILLIN; LACTAM; NETILMICIN; PENICILLIN G; RIFAMPICIN; VANCOMYCIN;

AGAR GEL DIFFUSION; ARTICLE; BIOASSAY; BONE ALLOGRAFT; CANCELLOUS BONE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG ADSORPTION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MICROBIOLOGY; MINIMUM INHIBITORY CONCENTRATION; ORTHOPEDICS; STAPHYLOCOCCUS AUREUS; THERMOSTABILITY;

EID: 0032793740     PISSN: 00016470     EISSN: None     Source Type: Journal    
DOI: 10.3109/17453679908997812     Document Type: Article

References (18)

1. Adams K, Couch L, Cierny G, Calhoun J, Mader J. In vitro and in vivo evaluation of antibiotic diffusion from antibiotic-impregnated polymethylmethacrylate beads. Clin Orthop 1992; 278: 244-52.
2. Becker P L, Smith R A, Williams R S, Dutkowsky J P. Comparison of antibiotic release from polymethylmethacrylate beads and sponge collagen. J Orthop Res 1994; 12: 737-41.
3. Buchholz H W, Elson R A, Engelbrecht E, Lodenkamper H, Rottger J, Siegel A. Management of deep infection of total hip replacement. J Bone Joint Surg (Br) 1981; 63 (7): 342-53.
4. Calhoun J H, Mader J T. Antibiotic heads in the management of surgical infections. Am J Surg 1989; 157: 443-9.
5. De Grood M. Het plomberen van resholten na osteomyelitis met "bone-chips". Ned Tijdschr V Gen 1947; 91.III.32: 2192-6.
6. Espehaug B, Engesaeter L B, Vollset S E, Havelin L I, Langeland N. Antibiotic prophylaxis in total hip arthroplasty. J Bone Joint Surg (Br) 1997; 79 (4): 590-5.
7. Humphrey J S, Mehta S, Seaber A V, Vail T P. Pharmacokinetics of a degradable drug delivery system in bone. Clin Orthop 1998; 349: 218-24.
8. Lindsey R W, Probe R, Miclau T, Alexander J W, Perren S M. The effects of antibiotic-impregnated autogenic can cellous bone graft on bone healing. Clin Orthop 1993; 291: 303-12.
9. McLaren A. Antibiotic-impregnated bone graft: Postop levels of vancomycin and tobramycin. Orthopaedic Trauma Assoc Annual Meeting 1988: 758-9.
10. McLaren A C, Miniaci A. In vivo study to determine the efficacy of cancellous bone graft as a delivery vehicle for antibiotics. The 12th annual meeting of the Society for Biomaterials. Minneapolis-St. Paul, Minnesota, USA. 1986: 102.
11. Miclau T, Dahners, L E, Lindsey, R W. In vitro pharmacokinetics of antibiotic release from locally implantable materials. J Orthop Res 1993; 11 (5): 627-32.
12. Mousset B, Benoit M A, Delloye C, Bouillet R, Gillard J. Biodegradable implants for potential use in bone infection. International Orthopaedics (SICOT). 1995; 19: 157-61.
13. Nie L, Nicolau D P, Nightingale C H, Browner B D, Quintiliani R. In vitro elution of ofloxacin from a bioabsorbable polymer. Acta Orthop Scand 1995; 66 (4): 365-8.
14. Penner M J, Masri B A, Duncan C P. Elution characteristics of vancomycin and tobramycin combined in acrylic bone-cement. J Arthroplasty 1996; 11 (8): 939-44.
15. Perry C R. Operative management of osteomyelitis. In: Bone and joint infections. Martin Dunitz Ltd, London 1996: 76-116.
16. Picknell B, Mizen L, Sutherland R. Antibacterial activity of antibiotics in acrylic bone cement. J Bone Joint Surg (Br) 1977; 59 (3): 302-7.
17. Tamashiro L. Broth microdilution MIC testing. In: Clinical microbiology procedures handbook (Ed. Isenberg H D). American Society for Microbiology, Washington. D.C. 1984: 521-29.
18. Walenkamp G H I M. Gentamicin-PMMA Beads. A clinical, pharmacokinetic and toxicological study. E. Merck. Darmstadt, Germany 1983: 43-6.