Wnt2 accelerates cardiac myocyte differentiation from ES-cell derived mesodermal cells via non-canonical pathway

Journal of Molecular and Cellular Cardiology

Volumn 52, Issue 3, 2012, Pages 650-659

  Onizuka, Takeshi ^a   Yuasa, Shinsuke ^a   Kusumoto, Dai ^a   Shimoji, Kenichiro ^a   Egashira, Toru ^a   Ohno, Yohei ^a   Kageyama, Toshimi ^a   Tanaka, Tomofumi ^a   Hattori, Fumiyuki ^a   Fujita, Jun ^a   Ieda, Masaki ^a   Kimura, Kensuke ^a   Makino, Shinji ^a   Sano, Motoaki ^a   Kudo, Akira ^b   Fukuda, Keiichi ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Cardiomyocyte; Embryonic stem cell; Induced pluripotent stem cells; Mesodermal cells; Non canonical pathway; Wnt

Indexed keywords

STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; WNT2 PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DEVELOPMENTAL STAGE; EMBRYO; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; FEMALE; GENE SILENCING; HEART DEVELOPMENT; HEART MUSCLE CELL; HUMAN; HUMAN CELL; MESODERM; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; EMBRYONIC STEM CELLS; GENE EXPRESSION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE SILENCING; HEART; HUMANS; MAP KINASE SIGNALING SYSTEM; MESODERM; MICE; MICE, INBRED ICR; MICE, TRANSGENIC; MYOCYTES, CARDIAC; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION FACTOR AP-1; WNT2 PROTEIN;

MURINAE;

EID: 84857639549     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2011.11.010     Document Type: Article

References (48)

1. Laflamme M.A., Murry C.E. Regenerating the heart. Nat Biotechnol 2005, 23:845-856.
2. Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
3. Seki T., Yuasa S., Oda M., Egashira T., Yae K., Kusumoto D., et al. Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells. Cell Stem Cell 2010, 7:11-14.
4. Yuasa S., Fukuda K. Recent advances in cardiovascular regenerative medicine: the induced pluripotent stem cell era. Expert Rev Cardiovasc Ther 2008, 6:803-810.
5. Shimoji K., Yuasa S., Onizuka T., Hattori F., Tanaka T., Hara M., et al. G-CSF promotes the proliferation of developing cardiomyocytes in vivo and in derivation from ESCs and iPSCs. Cell Stem Cell 2010, 6:227-237.
6. Fukuda K., Yuasa S. Stem cells as a source of regenerative cardiomyocytes. Circ Res 2006, 98:1002-1013.
7. Cohen E.D., Tian Y., Morrisey E.E. Wnt signaling: an essential regulator of cardiovascular differentiation, morphogenesis and progenitor self-renewal. Development 2008, 135:789-798.
8. Marvin M.J., Di Rocco G., Gardiner A., Bush S.M., Lassar A.B. Inhibition of Wnt activity induces heart formation from posterior mesoderm. Genes Dev 2001, 15:316-327.
9. Schneider V.A., Mercola M. Wnt antagonism initiates cardiogenesis in Xenopus laevis. Genes Dev 2001, 15:304-315.
10. Foley A.C., Mercola M. Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex. Genes Dev 2005, 19:387-396.
11. Manisastry S.M., Han M., Linask K.K. Early temporal-specific responses and differential sensitivity to lithium and Wnt-3A exposure during heart development. Dev Dyn 2006, 235:2160-2174.
12. Tzahor E., Lassar A.B. Wnt signals from the neural tube block ectopic cardiogenesis. Genes Dev 2001, 15:255-260.
13. Yamashita J.K., Takano M., Hiraoka-Kanie M., Shimazu C., Peishi Y., Yanagi K., et al. Prospective identification of cardiac progenitors by a novel single cell-based cardiomyocyte induction. FASEB J 2005, 19:1534-1536.
14. Lickert H., Kutsch S., Kanzler B., Tamai Y., Taketo M.M., Kemler R. Formation of multiple hearts in mice following deletion of beta-catenin in the embryonic endoderm. Dev Cell 2002, 3:171-181.
15. Nakamura T., Sano M., Songyang Z., Schneider M.D. A Wnt- and beta-catenin-dependent pathway for mammalian cardiac myogenesis. Proc Natl Acad Sci U S A 2003, 100:5834-5839.
16. Naito A.T., Shiojima I., Akazawa H., Hidaka K., Morisaki T., Kikuchi A., et al. Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesis. Proc Natl Acad Sci U S A 2006, 103:19812-19817.
17. Ueno S., Weidinger G., Osugi T., Kohn A.D., Golob J.L., Pabon L., et al. Biphasic role for Wnt/beta-catenin signaling in cardiac specification in zebrafish and embryonic stem cells. Proc Natl Acad Sci U S A 2007, 104:9685-9690.
18. Kwon C., Arnold J., Hsiao E.C., Taketo M.M., Conklin B.R., Srivastava D. Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors. Proc Natl Acad Sci U S A 2007, 104:10894-10899.
19. Eisenberg C.A., Gourdie R.G., Eisenberg L.M. Wnt-11 is expressed in early avian mesoderm and required for the differentiation of the quail mesoderm cell line QCE-6. Development 1997, 124:525-536.
20. Eisenberg C.A., Eisenberg L.M. WNT11 promotes cardiac tissue formation of early mesoderm. Dev Dyn 1999, 216:45-58.
21. Pandur P., Lasche M., Eisenberg L.M., Kuhl M. Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis. Nature 2002, 418:636-641.
22. Terami H., Hidaka K., Katsumata T., Iio A., Morisaki T. Wnt11 facilitates embryonic stem cell differentiation to Nkx2.5-positive cardiomyocytes. Biochem Biophys Res Commun 2004, 325:968-975.
23. Moriyama A., Kii I., Sunabori T., Kurihara S., Takayama I., Shimazaki M., et al. GFP transgenic mice reveal active canonical Wnt signal in neonatal brain and in adult liver and spleen. Genesis 2007, 45:90-100.
24. Yuasa S., Onizuka T., Shimoji K., Ohno Y., Kageyama T., Yoon S.H., et al. Zac1 is an essential transcription factor for cardiac morphogenesis. Circ Res 2010, 106:1083-1091.
25. Niwa H., Miyazaki J., Smith A.G. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet 2000, 24:372-376.
26. Nagy A., Rossant J., Nagy R., Abramow-Newerly W., Roder J.C. Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc Natl Acad Sci U S A 1993, 90:8424-8428.
27. Hooper M., Hardy K., Handyside A., Hunter S., Monk M. HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells. Nature 1987, 326:292-295.
28. Hara M., Yuasa S., Shimoji K., Onizuka T., Hayashiji N., Ohno Y., et al. G-CSF influences mouse skeletal muscle development and regeneration by stimulating myoblast proliferation. J Exp Med 2011, 208:715-727.
29. Yuasa S., Itabashi Y., Koshimizu U., Tanaka T., Sugimura K., Kinoshita M., et al. Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells. Nat Biotechnol 2005, 23:607-611.
30. Monkley S.J., Delaney S.J., Pennisi D.J., Christiansen J.H., Wainwright B.J. Targeted disruption of the Wnt2 gene results in placentation defects. Development 1996, 122:3343-3353.
31. Alexandrovich A., Arno M., Patient R.K., Shah A.M., Pizzey J.A., Brewer A.C. Wnt2 is a direct downstream target of GATA6 during early cardiogenesis. Mech Dev 2006, 123:297-311.
32. Tian Y., Yuan L., Goss A.M., Wang T., Yang J., Lepore J.J., et al. Characterization and in vivo pharmacological rescue of a Wnt2-Gata6 pathway required for cardiac inflow tract development. Dev Cell 2010, 18:275-287.
33. Kispert A., Herrmann B.G. Immunohistochemical analysis of the Brachyury protein in wild-type and mutant mouse embryos. Dev Biol 1994, 161:179-193.
34. Saga Y., Miyagawa-Tomita S., Takagi A., Kitajima S., Miyazaki J., Inoue T. MesP1 is expressed in the heart precursor cells and required for the formation of a single heart tube. Development 1999, 126:3437-3447.
35. Recillas-Targa F., Pikaart M.J., Burgess-Beusse B., Bell A.C., Litt M.D., West A.G., et al. Position-effect protection and enhancer blocking by the chicken beta-globin insulator are separable activities. Proc Natl Acad Sci U S A 2002, 99:6883-6888.
36. West A.G., Gaszner M., Felsenfeld G. Insulators: many functions, many mechanisms. Genes Dev 2002, 16:271-288.
37. DasGupta R., Fuchs E. Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation. Development 1999, 126:4557-4568.
38. Maretto S., Cordenonsi M., Dupont S., Braghetta P., Broccoli V., Hassan A.B., et al. Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors. Proc Natl Acad Sci U S A 2003, 100:3299-3304.
39. Mohamed O.A., Clarke H.J., Dufort D. Beta-catenin signaling marks the prospective site of primitive streak formation in the mouse embryo. Dev Dyn 2004, 231:416-424.
40. Yamaguchi T.P., Takada S., Yoshikawa Y., Wu N., McMahon A.P. T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification. Genes Dev 1999, 13:3185-3190.
41. Arnold S.J., Stappert J., Bauer A., Kispert A., Herrmann B.G., Kemler R. Brachyury is a target gene of the Wnt/beta-catenin signaling pathway. Mech Dev 2000, 91:249-258.
42. Lindsley R.C., Gill J.G., Kyba M., Murphy T.L., Murphy K.M. Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm. Development 2006, 133:3787-3796.
43. 2+ pathway to antagonize Wnt/{beta}-catenin signaling. Mol Cell Biol 2003, 23:131-139.
44. Tzahor E. Wnt/[beta]-catenin signaling and cardiogenesis: timing does matter. Dev Cell 2007, 13:10-13.
45. Logan C.Y., Nusse R. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 2004, 20:781-810.
46. Wang H., Gilner J.B., Bautch V.L., Wang D.-Z., Wainwright B.J., Kirby S.L., et al. Wnt2 coordinates the commitment of mesoderm to hematopoietic, endothelial, and cardiac lineages in embryoid bodies. J Biol Chem 2007, 282:782-791.
47. Kispert A., Vainio S., Shen L., Rowitch D.H., McMahon A.P. Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips. Development 1996, 122:3627-3637.
48. Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872.