Rescue of social behavior impairment by clozapine and alterations in the expression of neuronal receptors in a rat model of neurodevelopmental impairment induced by GRPR blockade

Journal of Neural Transmission

Volumn 119, Issue 3, 2012, Pages 319-327

  Presti Torres, Juliana ^a   Garcia, Vanessa Athaíde ^a,b   Dornelles, Arethuza ^a,b   Halmenschlager, Luís Henrique ^a,b   Alcalde, Luisa Azambuja ^a   Vedana, Gustavo ^a   Rico, Eduardo Pacheco ^a   Bogo, Maurício Reis ^a,b   Schwartsmann, Gilberto ^b,c,d   Roesler, Rafael ^b,c,d   Schröder, Nadja ^a,b  

^a PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b National Institute for Translational Medicine INCT TM   (Brazil)

^c FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^d HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

Author keywords

Clozapine; EGFR; Gastrin releasing peptide receptor; Neurodevelopmental disorders; NMDA receptor; Social behavior

Indexed keywords

CLOZAPINE; EPIDERMAL GROWTH FACTOR RECEPTOR; GASTRIN RELEASING PEPTIDE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; RC 3095;

ADULTHOOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTISM; BRAIN CORTEX; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; DOSE RESPONSE; DRUG EFFECT; EXPERIMENTAL MODEL; GENE EXPRESSION; HIPPOCAMPUS; MALE; MEMORY; NERVOUS SYSTEM DEVELOPMENT; NEWBORN; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; RAT; RECOGNITION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOCIAL INTERACTION; SOCIOPATHY;

ANIMALS; ANTIPSYCHOTIC AGENTS; BEHAVIOR, ANIMAL; BOMBESIN; CEREBRAL CORTEX; CLOZAPINE; FEMALE; HIPPOCAMPUS; MALE; NEURONS; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR; RECEPTORS, BOMBESIN; RECOGNITION (PSYCHOLOGY); SOCIAL BEHAVIOR;

EID: 84857636270     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-011-0695-5     Document Type: Article

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