Proteasome inhibition by quercetin triggers macroautophagy and blocks mTOR activity

Histochemistry and Cell Biology

Volumn 137, Issue 1, 2012, Pages 25-36

  Klappan, Anja K ^a   Hones, Stefanie ^a   Mylonas, Ioannis ^a   Brüning, Ansgar ^a,b  

^a UNIVERSITY OF MUNICH   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Autophagy; Bortezomib; MTOR; Nelfinavir; Proteasome; Quercetin

Indexed keywords

INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; PROTEASOME; QUERCETIN; S6 KINASE;

AGGRESOME; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; CELL ACTIVITY; CELL CYCLE ARREST; CELL DEATH; CELL PROLIFERATION; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; MACROAUTOPHAGY; PHAGOLYSOSOME; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION;

ANTINEOPLASTIC AGENTS; AUTOPHAGY; CELL CYCLE; CELL DEATH; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; HELA CELLS; HUMANS; PROTEASOME ENDOPEPTIDASE COMPLEX; QUERCETIN; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TOR SERINE-THREONINE KINASES; TUMOR CELLS, CULTURED;

EID: 84857627775     PISSN: 09486143     EISSN: 1432119X     Source Type: Journal    
DOI: 10.1007/s00418-011-0869-0     Document Type: Article

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