Optimized preparation method of platelet-concentrated plasma and noncoagulating platelet-derived factor concentrates: Maximization of platelet concentration and removal of fibrinogen

Tissue Engineering - Part C: Methods

Volumn 18, Issue 3, 2012, Pages 176-185

  Araki, Jun ^a   Jona, Masahiro ^a   Eto, Hitomi ^a   Aoi, Noriyuki ^a   Kato, Harunosuke ^a   Suga, Hirotaka ^a   Doi, Kentaro ^a   Yatomi, Yutaka ^a   Yoshimura, Kotaro ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; CENTRIFUGATION; CENTRIFUGES; CITRIC ACID; ETHYLENE; OPTIMIZATION; PEPTIDES; PLASMAS; TISSUE;

ACID CITRATE DEXTROSE; ANGIOGENESIS; FIBRIN GELS; FIBRIN GLUE; GROWTH FACTOR; PDGF BB'S; PLATELET ACTIVATION; PLATELET AGGREGATION; PLATELET-DERIVED GROWTH FACTORS; PLATELET-RICH PLASMA; PREPARATION METHOD; THERAPEUTIC EFFECTS; TISSUE REMODELING; WHOLE BLOOD; WOUND HEALING;

PLATELETS;

TETRA;

BLOOD CLOTTING FACTOR; FIBRINOGEN; PLATELET DERIVED GROWTH FACTOR;

ADULT; APHERESIS; ARTICLE; CALIBRATION; CHEMISTRY; EVALUATION; FEMALE; HUMAN; ISOLATION AND PURIFICATION; MALE; METABOLISM; METHODOLOGY; MIDDLE AGED; OSMOLARITY; PHYSIOLOGY; STANDARD; THROMBOCYTE; THROMBOCYTE COUNT; THROMBOCYTE RICH PLASMA;

ADULT; BLOOD COAGULATION FACTORS; BLOOD COMPONENT REMOVAL; BLOOD PLATELETS; CALIBRATION; FEMALE; FIBRINOGEN; HUMANS; MALE; MIDDLE AGED; OSMOLAR CONCENTRATION; PLATELET COUNT; PLATELET-DERIVED GROWTH FACTOR; PLATELET-RICH PLASMA;

EID: 84857582181     PISSN: 19373384     EISSN: 19373392     Source Type: Journal    
DOI: 10.1089/ten.tec.2011.0308     Document Type: Article

References (34)

1. Flatow, F.A., Jr., and Freireich, E.J. The increased effectiveness of platelet concentrates prepared in acidified plasma. Blood 27, 449, 1966.
2. Boldt, J., von Bormann, B., Kling, D., Jacobi, M., Moosdorf, R., and Hempelmann, G. Preoperative plasmapheresis in patients undergoing cardiac surgery procedures. Anesthesiology 72, 282, 1990.
3. Weibrich, G., Kleis, W.K., Hafner, G., and Hitzler, W.E. Growth factor levels in platelet-rich plasma and correlations with donor age, sex, and platelet count. J Craniomaxillofac Surg 30, 97, 2002.
4. Eppley, B.L., Woodell, J.E., and Higgins, J. Platelet quantification and growth factor analysis from platelet-rich plasma: implications for wound healing. Plast Reconstr Surg 114, 1502, 2004.
5. Aiba-Kojima, E., Tsuno, N.H., Inoue, K., Matsumoto, D., Shigeura, T., Sato, T., Suga, H., Kato, H., Nagase, T., Gonda, K., Koshima, I., Takahashi, K., and Yoshimura, K. Characterization of wound drainage fluids as a source of soluble factors associated with wound healing: comparison with platelet-rich plasma and potential use in cell culture. Wound Repair Regen 15, 511, 2007.
6. Gnecchi, M., Zhang, Z., Ni, A., and Dzau, V.J. Paracrine mechanisms in adult stem cell signaling and therapy. Circ Res 103, 1204, 2008.
7. Mimeault, M., and Batra, S.K. Recent advances on skinresident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti-aging and cancer therapies. J Cell Mol Med 14, 116, 2010.
8. Lucarelli, E., Beccheroni, A., Donati, D., Sangiorgi, L., Cenacchi, A., Del Vento, A.M., Meotti, C., Bertoja, A.Z., Giardino, R., Fornasari, P.M., Mercuri, M., and Picci, P. Platelet-derived growth factors enhance proliferation of human stromal stem cells. Biomaterials 24, 3095, 2003.
9. Anitua, E., Andia, I., Ardanza, B., Nurden, P., and Nurden, A.T. Autologous platelets as a source of proteins for healing and tissue regeneration. Thromb Haemost 91, 4, 2004.
10. Niemeyer, P., Fechner, K., Milz, S., Richter, W., Suedkamp, N.P., Mehlhorn, A.T., Pearce, S., and Kasten, P. Comparison of mesenchymal stem cells from bone marrow and adipose tissue for bone regeneration in a critical size defect of the sheep tibia and the influence of platelet-rich plasma. Biomaterials 31, 3572, 2010.
11. Marx, R.E., Carlson, E.R., Eichstaedt, R.M., Schimmele, S.R., Strauss, J.E., and Georgeff, K.R. Platelet-rich plasma: growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 85, 638, 1998.
12. Khalafi, R.S., Bradford, D.W., and Wilson, M.G. Topical application of autologous blood products during surgical closure following a coronary artery bypass graft. Eur J Cardiothorac Surg 34, 360, 2008.
13. Alio, J.L., Abad, M., Artola, A., Rodriguez-Prats, J.L., Pastor, S., and Ruiz-Colecha, J. Use of autologous platelet-rich plasma in the treatment of dormant corneal ulcers. Ophthalmology 114, 1286, 2007.
14. Nikolidakis, D., and Jansen, J.A. The biology of platelet-rich plasma and its application in oral surgery: literature review. Tissue Eng Part B Rev 14, 249, 2008.
15. Savarino, L., Cenni, E., Tarabusi, C., Dallari, D., Stagni, C., Cenacchi, A., Fornasari, P.M., Giunti, A., and Baldini, N. Evaluation of bone healing enhancement by lyophilized bone grafts supplemented with platelet gel: a standardized methodology in patients with tibial osteotomy for genu varus. J Biomed Mater Res B Appl Biomater 76, 364, 2006.
16. Eppley, B.L., Pietrzak, W.S., and Blanton, M. Platelet-rich plasma: a review of biology and applications in plastic surgery. Plast Reconstr Surg 118, 147, 2006.
17. Pallua, N., Wolter, T., and Markowicz, M. Platelet-rich plasma in burns. Burns 36, 4, 2010.
18. Foster, T.E., Puskas, B.L., Mandelbaum, B.R., Gerhardt, M.B., and Rodeo, S.A. Platelet-rich plasma: from basic science to clinical applications. Am J Sports Med 37, 2259, 2009.
19. Anitua, E., Sánchez, M., Nurden, A.T., Nurden, P., Orive, G., and Andía, I. New insights into and novel applications for platelet-rich fibrin therapies. Trends Biotechnol 24, 227, 2006.
20. Man, D., Plosker, H., and Winland-Brown, J.E. The use of autologous platelet-rich plasma (platelet gel) and autologous platelet-poor plasma (fibrin glue) in cosmetic surgery. Plast Reconstr Surg 107, 229, 2001.
21. Freymiller, E.G., and Aghaloo, T.L Platelet-rich plasma: ready or not? J Oral Maxillofac Surg 62, 484, 2004
22. Coombes, B.K., Bisset, L., and Vicenzino, B. Efficacy and safety of corticosteroid injections and other injections for management of tendinopathy: a systematic review of randomised controlled trials. Lancet 376, 1751, 2010.
23. Dohan Ehrenfest, D.M., Rasmusson, L., and Albrektsson, T. Classification of platelet concentrates: from pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF). Trends Biotechnol 27, 158, 2009.
24. Anitua, E., Sánchez, M., Orive, G, and Andía, I. The potential impact of the preparation rich in growth factors (PRGF) in different medical fields. Biomaterials 28, 4551, 2007.
25. Plötner, R. Handbuch der gesamter Hämatologie, Band 11/ 2, zweiter Halbband, M}unchen, Berlin: Urban & Schwanzenberg, 1960, p. 254.
26. Kurita, M., Aiba-Kojima, E., Shigeura, T., Matsumoto, D., Suga, H., Inoue, K., Eto, H., Kato, H., Aoi, N., and Yoshimura, K. Differential effects of three preparations of human serum on expansion of various types of human cells. Plast Reconstr Surg 122, 438, 2008.
27. Slichter, S.J., and Harker, L.A. Preparation and storage of platelet concentrates. I. Factors influencing the harvest of viable platelets from whole blood. Br J Haematol 34, 395, 1976.
28. Zimmermann, R., Reske, S., Metzler, P., Schlegel, A., Ringwald, J., and Eckstein, R. Preparation of highly concentrated and white cell-poor platelet-rich plasma by plateletpheresis. Vox Sang 95, 20, 2008.
29. Castillo, T.N., Pouliot, M.A., Kim, H.J., and Dragoo, J.L. Comparison of growth factor and platelet concentration from commercial platelet-rich plasma separation systems. Am J Sports Med 39, 266, 2011.
30. McShine, R.L., Sibinga, S., and Brozovic, B. Differences between the effects of EDTA and citrate anticoagulants on platelet count and mean platelet volume. Clin Lab Haematol 12, 277, 1990.
31. Catelas, I., Dwyer, J.F., and Helgerson, S. Controlled release of bioactive transforming growth factor beta-1 from fibrin gels in vitro. Tissue Eng Part C Methods 14, 119, 2008.
32. Hoben, G., Schmidt, V.J., Bannasch, H., and Horch, R.E. Tissue augmentation with fibrin sealant and cultured fibroblasts: a preliminary study. Aesthetic Plast Surg 2011 [Epub ahead of print]; DOI: 10.1007/S00266-011-9724-x.
33. Eto, H., Suga, H., Aoi, N, Kato, H., Araki, J., Doi, K., Higashino, T., and Yoshimura, K. Adipose injury-associated factors activate adipose stem/stromal cells, induce neoangiogenesis, and mitigate hypoxia in ischemic tissues. Am J Pathol 178, 2322, 2011.
34. Martínez-Zapata, M.J., Martí-Carvajal, A., Solà, I., Bolibar, I., Angel Expósito, J., Rodriguez, L., and García, J. Efficacy and safety of the use of autologous plasma rich in platelets for tissue regeneration: a systematic review. Transfusion 49, 44, 2009.