Efficacy and safety of the use of autologous plasma rich in platelets for tissue regeneration: A systematic review

Transfusion

Volumn 49, Issue 1, 2009, Pages 44-56

  Martínez Zapata, Ma José ^a   Martí Carvajal, Arturo ^b   Solà, Ivan ^b   Bolibar, Ignasi ^b   Ángel Expósito, José ^b   Rodriguez, Luciano ^b   García, Joan ^b  

^a HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADVERSE OUTCOME; ARTICLE; BLOOD TRANSFUSION; CHRONIC DISEASE; CLINICAL STUDY; DRUG EFFICACY; DRUG SAFETY; ELECTRONIC MEDICAL RECORD; EPITHELIZATION; GINGIVA DISEASE; HUMAN; MAXILLOFACIAL SURGERY; METHODOLOGY; ORAL SURGERY; PERIODONTITIS; RISK FACTOR; SENSITIVITY ANALYSIS; SKIN ULCER; SURGICAL WOUND; SYSTEMATIC REVIEW; THROMBOCYTE RICH PLASMA; TISSUE REGENERATION;

BLOOD TRANSFUSION, AUTOLOGOUS; CHRONIC DISEASE; CHRONIC PERIODONTITIS; HUMANS; PLATELET TRANSFUSION; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SAFETY; SKIN ULCER; SURGERY, ORAL; WOUND HEALING;

EID: 58149105331     PISSN: 00411132     EISSN: 15372995     Source Type: Journal    
DOI: 10.1111/j.1537-2995.2008.01945.x     Document Type: Article

References (57)

1. Marx RE, Carlson ER, Eichstaedt RM, Schimmele SR, Strauss JE, Georgeff KR. Platelet-rich plasma: growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998 85 : 638 46.
2. Anitua E, Andia I, Ardanza B, Nurden P, Nurden AT. Autologous platelets as a source of proteins for healing and tissue regeneration. Thromb Haemost 2004 92 : 1 12.
3. Savarino L, Cenni E, Tarabusi C, Dallari D, Stagni C, Cenacchi A, Fornasari PM, Giunti A, Baldini N. Evaluation of bone healing enhancement by lyophilized bone grafts supplemented with platelet gel: a standardized methodology in patients with tibial osteotomy for genu varus. J Biomed Mater Res B Appl Biomater 2006 76 : 364 72.
4. Hanna R, Trejo PM, Weltman RL. Treatment of intrabony defects with bovine-derived xenograft alone and in combination with platelet-rich plasma: a randomized clinical trial. J Periodontol 2004 75 : 1668 77.
5. Powell DM, Chang E, Farrior EH. Recovery from deep-plane rhytidectomy following unilateral wound treatment with autologous platelet gel: a pilot study. Arch Facial Plast Surg 2001 3 : 245 50.
6. Englert SJ, Estep TH, Ellis-Stoll CC. Autologous platelet gel applications during cardiovascular surgery: effect on wound healing. J Extra Corpor Technol 2005 37 : 148 52.
7. Knighton DR, Doucette M, Fiegel VD, Ciresi K, Butler E, Austin L. The use of platelet derived wound healing formula in human clinical trials. Prog Clin Biol Res 1988 266 : 319 29.
8. Robinson CJ. Growth factors: therapeutic advances in wound healing. Ann Med 1993 25 : 535 8.
9. Crovetti G, Martinelli G, Issi M, Barone M, Guizzardi M, Campanati B, Moroni M, Englert SJ, Estep TH, Ellis-Stoll CC. Autologous platelet gel applications during cardiovascular surgery: effect on wound healing. J Extra Corpor Technol 2005 37 : 148 52.
10. Korobelnik JF, Hannouche D, Belayachi N, Branger M, Guez JE, Hoang-Xuan T. Autologous platelet concentrate as an adjunct in macular hole healing: a pilot study. Ophthalmology 1996 103 : 590 4.
11. Munirah S, Samsudin OC, Chen HC, Sharifah Salmah SH, Aminuddin BS, Ruszymah BH, MD. Articular cartilage restoration in load-bearing osteochondral defects by implantation of autologous chondrocyte-fibrin constructs. J Bone Joint Surg Br 2007 89 B : 1099 109.
12. Sanchez AR, Sheridan PJ, Kupp LI. Is platelet-rich plasma the perfect enhancement factor? A current review. Int J Oral Maxillofac Implants 2003 18 : 93 103.
13. Whitman DH, Berry RL, Green DM. Platelet gel: an autologous alternative to fibrin glue applications in oral and maxillofacial surgery. J Oral Maxillofac Surg 1997 55 : 1294 9.
14. Imrey PB, Chilton NW. Design and analytic concepts for periodontal clinical trials. J Periodontol 1992 63 12 Suppl : 1124 40.
15. Robinson KA, Dickersin K. Development of a highly sensitive search strategy for the retrieval of reports of controlled trials using PubMed. Source Int J Epidemiol 2002 31 : 150 3.
16. Tarpila E, Jergovic D, Sjoberg F, Bjornsson A, Abildgard L, Rosseau A. Autologous platelet-derived wound healing factors in the treatment of leg ulcers with split-skin grafts. New Approaches to the Management of Chronic Wounds 1998 81 5.
17. Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, McQuay HJ. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996 17 : 1 12.
18. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986 7 : 177 88.
19. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ 2003 327 : 557 60.
20. Camargo PM, Lekovic V, Weinlaender M, Vasilic N, Madzarevic M, Kenney EB. A reentry study on the use of bovine porous bone mineral, GTR, and platelet-rich plasma in the regenerative treatment of intrabony defects in humans. Int J Periodontics Restorative Dent 2005 25 : 49 59.
21. Franchini M, Dupplicato P, Ferro I, De Gironcoli M, Aldegheri R. Efficacy of platelet gel in reconstructive bone surgery. Orthopedics 2005 28 : 161 3.
22. Froum SJ, Wallace SS, Tarnow DP, Cho SC. Effect of platelet-rich plasma on bone growth and osseointegration in human maxillary sinus grafts: three bilateral case reports. Int J Periodontics Restorative Dent 2002 22 : 45 53.
23. Lekovic V, Camargo PM, Weinlaender M, Vasilic N, Kenney EB. Comparison of platelet-rich plasma, bovine porous bone mineral, and guided tissue regeneration versus platelet-rich plasma and bovine porous bone mineral in the treatment of intrabony defects: a reentry study. J Periodontol 2002 73 : 198 205.
24. Maiorana C, Sommariva L, Brivio P, Sigurta D, Santoro F. Maxillary sinus augmentation with anorganic bovine bone (Bio-Oss) and autologous platelet-rich plasma: preliminary clinical and histologic evaluations. Int J Periodontics Restorative Dent 2003 23 : 227 35.
25. Monov G, Fuerst G, Tepper G, Watzak G, Zechner W, Watzek G. The effect of platelet-rich plasma upon implant stability measured by resonance frequency analysis in the lower anterior mandibles. Clin Oral Implants Res 2005 16 : 461 5.
26. Robiony M, Polini F, Costa F, Politi M. Osteogenesis distraction and platelet-rich plasma for bone restoration of the severely atrophic mandible: preliminary results. J Oral Maxillofac Surg 2002 60 : 630 5.
27. Sammartino G, Tia M, Marenzi G, di Lauro AE, D'Agostino E, Claudio PP. Use of autologous platelet-rich plasma (PRP) in periodontal defect treatment after extraction of impacted mandibular third molars. J Oral Maxillofac Surg 2005 63 : 766 70.
28. Atri SC, Misra J, Bisht D, Misra K. Use of homologous platelet factors in achieving total healing of recalcitrant skin ulcers. Surgery 1990 108 : 508 12.
29. Margolis DJ, Kantor J, Santanna J, Strom BL, Berlin JA. Effectiveness of platelet releasate for the treatment of diabetic neuropathic foot ulcers. Diabetes Care 2001 24 : 483 8.
30. Mazzucco L, Medici D, Serra M, Panizza R, Rivara G, Orecchia S, Libener R, Cattana E, Levis A, Betta PG, Borzini P. The use of autologous platelet gel to treat difficult-to-heal wounds: a pilot study. Transfusion 2004 44 : 1013 8.
31. Reutter H, Bort S, Jung MF, Klyscz T, Schippert W, Zuder D, Junger M. Questionable effectiveness of autologous platelet growth factors (PDHWF) in the treatment of venous leg ulcers. Hautarzt 1999 50 : 859 65.
32. Saldalamacchia G, Lapice E, Cuomo V, De Feo E, D'Agostino E, Rivellese AA, Vaccaro O. A controlled study of the use of autologous platelet gel for the treatment of diabetic foot ulcers. Nutr Metab Cardiovasc Dis 2004 14 : 395 6.
33. Steed DL, Goslen JB, Holloway GA, Malone JM, Bunt TJ, Webster MW. Randomized prospective double-blind trial in healing chronic diabetic foot ulcers. CT-102 activated platelet supernatant, topical versus placebo. Diabetes Care 1992 15 : 1598 604.
34. Ehrlich HP, Freedman BM. Topical platelet-derived growth factor in patients enhances wound closure in the absence of wound contraction. Cytokines Cell Mol Ther 2002 7 : 85 90.
35. Floryan KM, Berghoff WJ. Intraoperative use of autologous platelet-rich and platelet-poor plasma for orthopedic surgery patients. AORN J 2004 80 : 668 74 quiz 675 8.
36. Mishra A, Pavelko T. Treatment of chronic elbow tendinosis with buffered platelet-rich plasma. Am J Sports Med 2006 34 : 1774 78.
37. Wright-Carpentier T, Klein P, Schäferhoff P, Apell HJ, Mir LM, Wehling P. Treatment of muscle injures by local administration of autologous conditioned serum: a pilot study on sportsmen with muscle strains. Int J Sport Med 2004 25 : 588 93.
38. Castro FP Jr. Role of activated growth factors in lumbar spinal fusions. J Spinal Disord Tech 2004 17 : 380 4.
39. Lowery GL, Kulkarni S, Pennisi AE. Use of autologous growth factors in lumbar spinal fusion. Bone 1999 25 Suppl 1 : 47S 50S.
40. Anitua E. Plasma rich in growth factors: preliminary results of use in the preparation of future sites for implants. Int J Oral Maxillofacial Implants 1999 14 : 529 35.
41. Böhm S, Kurtulus I, Gonzales J, Meyle J. Effect of platelet-rich protein on early wound healing in intrabony defects. Annual Meeting of the American Academy of Peridontology. San Francisco. J Periodontol 2003. Abstract. Pg. 1705.
42. Wiltfang J, Schlegel KA, Schultze-Mosgau S, Nkenke E, Zimmermann R, Kessler P. Sinus floor augmentation with beta-tricalciumphosphate (beta-TCP): does platelet-rich plasma promote its osseous integration and degradation? Clin Oral Implants Res 2003 14 : 213 8.
43. Cheung WS, Griffin TJ. A comparative study of root coverage with connective tissue and platelet concentrate grafts: 8-month results. J Periodontol 2004 75 : 1678 87.
44. Simon D, Manuel S, Geetha V, Naik BR. Potential for osseous regeneration of platelet-rich plasma - a comparative study in mandibular third molar sockets. Indian J Dent Res 2004 15 : 133 6.
45. Huang LH, Neiva RE, Soehren SE, Giannobile WV, Wang HL. The effect of platelet-rich plasma on the coronally advanced flap root coverage procedure: a pilot human trial. J Periodontol 2005 76 : 1768 77.
46. Okuda K, Tai H, Tanabe K, Suzuki H, Sato T, Kawase T, Saito Y, Wolff LF, Yoshiex H. Platelet-rich plasma combined with a porous hydroxyapatite graft for the treatment of intrabony periodontal defects in humans: a comparative controlled clinical study. J Periodontol 2005 76 : 890 8.
47. Raghoebar GM, Schortinghuis J, Liem RS, Ruben JL, van der Wal JE, Vissink A. Does platelet-rich plasma promote remodeling of autologous bone grafts used for augmentation of the maxillary sinus floor? Clin Oral Implants Res 2005 16 : 349 56.
48. Steigmann M, Garg AK. A comparative study of bilateral sinus lifts performed with platelet-rich plasma alone versus alloplastic graft material reconstituted with blood. Implant Dent 2005 14 : 261 6.
49. Knighton DR, Ciresi K, Fiegel VD, Schumerth S, Butler E, Cerra F. Stimulation of repair in chronic, nonhealing, cutaneous ulcers using platelet-derived wound healing formula. Surg Gynecol Obstet 1990 170 : 56 60.
50. Krupski WC, Reilly LM, Perez S, Moss KM, Crombleholme PA, Rapp JH. A prospective randomized trial of autologous platelet-derived wound healing factors for treatment of chronic nonhealing wounds: a preliminary report. J Vasc Surg 1991 14 : 526 32 discussion 532 6.
51. Stacey MC, Mata SD, Trengove NJ, Mather CA. Randomised double-blind placebo controlled trial of topical autologous platelet lysate in venous ulcer healing. Eur J Vasc Endovasc Surg 2000 20 : 296 301.
52. Senet P, Bon FX, Benbunan M, Bussel A, Traineau R, Calvo F, Dubertret L, Dosquet C. Randomized trial and local biological effect of autologous platelets used as adjuvant therapy for chronic venous leg ulcers. J Vasc Surg 2003 38 : 1342 8.
53. Aguirre JJ, Francisco S, Cabezas A, Calleja A, Ayerdi E, Pena MA, Algorta J. Ensayo clínico piloto, aleatorizado, en grupos paralelos, ciego y controlado con tratamiento convencional para evaluar la eficacia de plasma rico en factores de crecimiento en el tratamiento de las úlceras cutáneas: resultados a las 4 semanas de seguimiento. XIX Congreso de la Sociedad Española de Farmacología Clínica. Santander 2004 28 30 Octubre. Abstract 19:12.
54. Weed B, Davis MD, Felty CL, Liedl DA, Pineda AA, Moore SB, Rooke TW. Autologous platelet lysate product versus placebo in patients with chronic leg ulcerations: a pilot study using a randomized, double-blind, placebo-controlled trial. Wounds-A Compend Clin Res Pract 2004 16 : 273 82.
55. Driver VR, Hanft J, Fylling CP, Beriou JM. A prospective, randomized, controlled trial of autologous platelet-rich plasma gel for the treatment of diabetic foot ulcers. Ostomy Wound Manage 2006 52 : 68 87.
56. Gunsolley J, Elswick RK, Davenport JM. Equivalence and superiority testing in regeneration clinical trials. J Periodontol 1998 69 : 521 7.
57. Plachokova AS, Nikolidakis D, Mulder J, Jansen JA, Creugers NH. Effect of platelet-rich plasma on bone regeneration in dentistry: a systematic review. Clin Oral Implants Res 2008 19 : 539 45.